Embryological considerations and evaluation of congenital anomalies of craniovertebral junction: A single-center experience by Reddy Ravikanth, Pooja Majumdar

“…The present study was undertaken to know the embryological basis of the CVJ and to identify commonly observed congenital CVJ abnormalities, their frequency, and mode of presentation. Materials and Methods: Diagnosed cases of CVJ anomalies on dynamic MDCT head were reviewed at a tertiary care center between January 2014 to December 2019. …”
Get full text

Impact of New-Onset Atrial Fibrillation on Mortality in Critically Ill Patients by Zhang HD, Ding L, Mi LJ, Zhang AK, Liu YD, Li XN, Yan XX, Shen YJ, Tang M

“…This study sought to evaluate the impact of new-onset AF on mortality in a critically ill population.Methods: This study identified 48018 adult patients admitted to the ICU from the Medical Information Mart for Intensive Care (MIMIC)-IV database. …”
Get full text

A Risk Model Based on sCD25 for Early Mortality in Adult Patients with Hemophagocytic Lymphohistiocytosis by Li C, Lv K, Zhou Y, Cheng X, Li F

“…We aim to investigate the characteristics of the early death (ED) in adults with HLH and develop a reliable risk model to predict early mortality.Materials and Methods: Between September 2013 and July 2024, 254 adult patients with HLH were examined. …”
Get full text

Preferences for home-based care services during China’s long-term care market transition: evidence from a discrete choice experiment by Zihan Ni, Xiuyuan Zhu, Jing Guo, Shiyu Xie, Shimeng Liu, Xiaoguang Yang

“…Objective This study examines the preferences of Chinese residents aged 25 or above for home-based care services, focusing on the relative importance of key service attributes, willingness to pay, and preference heterogeneity across demographic groups. Methods A discrete choice experiment (DCE) was conducted from September 2024 to January 2025, with 680 valid responses from 21 provinces in China we're included for analysis. …”
Get full text

EFFICACY AND SAFETY OF A NEW COMBINED MEDICATION WITH RECOMBINANT INTERFERON AND BETAMETHASONE IN THE TREATMENT OF HAY FEVER DURING PERIODS OF EXACERBATION by A. A. Ryabtseva, N. Y. Sotnikova, O. V. Chumikov, N. A. Stupakova

“…Objective: to assess the efficacy, safety and tolerability of the new combined medication Allergoferon® beta in patients with moderate-to-severe hay fever (seasonal allergic rhinitis and conjunctivitis) during periods of exacerbation. patients and methods: the object of our study was medication Allergoferon® beta (recombinant human interferon alpha-2b, not less than 5000 IU/ml + betamethasone sodium phosphate, 1.0 mg/ml) in the form of eye and nasal drops. …”
Get full text

TWELVE-WEEK MULTICENTER OPEN-LABEL RANDOMIZED COMPARATIVE STUDY OF THE EFFICACY AND SAFETY OF METHOTREXATE AS A CONCENTRATED SOLUTION FOR SUBCUTANEOUS ADMINISTRATION AND AS 15-MG T... by Yu. V. Muravyev, V. I. Mazurov, E. L. Nasonov

“…Objective: to evaluate of the efficacy of methotrexate (MTX) as a concentrated solution (50 mg/ml) for subcutaneous administration versus coated tablets at equal oral doses of 15 mg/week for rheumatoid arthritis (RA).Subjects and methods. …”
Get full text

Mean perfusion pressure in cardiopulmonary bypass as a factor of intraoperative acute kidney injury by D. V. Sokolov, R. V. Akmalova, N. S. Molchan, I. V. Bovkun, O. V. Galkina, Yu. S. Polushin

“…The OBJECTIVE was to evaluate the role of mean perfusion pressure in the development of acute kidney injury (AKI) in patients operated with CPB.METHODS AND MATERIALS. A retrospective monocenter observational study was conducted among patients CPB (n=97) who underwent planned heart surgery using CPB. …”
Get full text

Comparative Study and Transcriptomic Analysis on the Antifungal Mechanism of Ag Nanoparticles and Nanowires Against Trichosporon asahii by Han M, Xia Z, Zou Y, Hu P, Zhang M, Yang X, Ma MG, Yang R

“…However, the antifungal mechanism of silver nanomaterials with different morphologies still needs to be explored.Methods: Herein, the antifungal effect of silver nanomaterials against fungus was comparative investigated via silver nanowires and silver nanoparticles with a similar size (30 nm).Results: The optimal antifungal concentration of silver nanowires is 6.24 μg/mL, meanwhile the antifungal concentration of silver nanoparticles is 100 μg/mL. …”
Get full text

Graphene Oxide Nanosheets Induce Mitochondrial Toxicity in Human Ovarian Granulosa Cells: Implications for Female Reproductive Health by Li M, Lu H, Ye C, Wang X, Ji D, Zhang Z, Cao Y, Zou W

“…This study investigates the short-term effects of a single dose of GO nanosheets on human ovarian granulosa cells, focusing on mitochondrial damage.Materials and Methods: First, cell viability was detected by CCK-8 and apoptosis was detected by flow cytometry to assess the cytotoxicity of GO on KGN. …”
Get full text

A Psychometric Analysis of the Polish Online Version of the Aging Semantic Differential Scale (ASD) by Puto G, Wadelska-Kaczmarek A, Muszalik M

“…The aim of the study was to analyse the psychometrics of the Polish online version of the Aging Semantic Differential Scale (ASD).Methods: The study was conducted among 384 students of bachelor’s and master’s degree studies in nursing (94.3%) and other medical disciplines: midwifery and emergency medical services (5.7%). …”
Get full text

Diagnostic Performance of Infrared Thermography, Quantitative Sudomotor Axonal Reflex Testing, and 3-Phase Bone Scintigraphy for Complex Regional Pain Syndrome Diagnosis: A Retrosp... by Noh C, Lee J, Choi HY, Park E, Shin YS, Hong B, Ko Y, Oh C, Lee SY

“…This retrospective study aimed to elucidate the diagnostic validity and potential value of these modalities for the diagnosis of CRPS.Patients and Methods: The Budapest criteria were used to diagnose CRPS, and infrared thermography, QSART, and 3-phase bone scintigraphy were performed as ancillary tests. …”
Get full text

Effect and Safety of Finerenone in Patients with IgA Nephropathy by Guo Y, Zhang X, Zhao S, Wang Y, Wang L, Li Q, Yu L, Tang L

“…Yanhong Guo,* Xuewen Zhang,* Silu Zhao,* Yulin Wang, Liuwei Wang, Qiuhong Li, Lu Yu, Lin Tang Department of Nephropathy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lin Tang, Department of Nephropathy, the First Affiliated Hospital of Zhengzhou University, No. 1 East Jianshe Road, Zhengzhou, Henan, 450052, People’s Republic of China, Tel +8613838194409, Email tanglin@zzu.edu.cnPurpose: The study aimed to retrospectively evaluate the efficacy and safety of finerenone in patients diagnosed with IgA nephropathy.Methods: 42 IgA nephropathy patients treated with finerenone combined with renin–angiotensin system inhibitor (RASI) and 42 patients who received RASI monotherapy were included in this study. …”
Get full text

Childhood Maltreatment and Internet Addiction: A Moderated Mediation Model of Depression and Physical Activities by Li S, Zhang L, Song L, Fan T, Li Y, Shen Y

“…This study investigates the mediating role of depression and the moderating role of physical activity in the relationship between childhood maltreatment and adolescent internet addiction.Methods: Data from 1610 Chinese middle school students were analyzed using statistical software: Mplus 8.3 was used for SEM, while SPSS 26.0 and Hayes’ PROCESS Macro were used for correlation analyses, hierarchical regression, and moderated mediation model.Results: Results showed that emotional abuse was significantly positively associated with internet addiction and the association was mediated by depression. …”
Get full text

Is Race Associated with Referral Disparities for Patients with Diabetic Foot Ulcers? by Kyle M. Schweser MD, Mubinah Khaleel DO, Ashwin Garlapaty, Sam Hawkins, James Cook DVM, PhD, Kylee Rucinski PhD, MHA

“…This retrospective study was designed to determine 1) the associations of race and living status with rates of referral to specialists for DFU treatment, and 2) the severity of DFU at time of initial presentation. Methods: Patients were identified from the medical record based on a diagnosis related to diabetic foot ulcers made between January 01, 2018, and June 01, 2023, in the family medicine clinic, endocrinology clinic, or emergency department at a Midwest Level 1 Academic Hospital. …”
Get full text

The effect of a session of moderate intensity aerobic exercise on inflammatory factors and flow-mediated dilation in pre-menopausal and post-menopausal women by Arsalan Damirchi, Sanaz Shiravi

“…The aim of this research was to determine the effect of a session of aerobic exercise with moderate intensity on interleukins 6 and 8, TNF-α, as well as vascular function (flow mediated dilation) in premenopausal and postmenopausal women.Materials and methods: In this semi-experimental study, 30 inactive women without any cardiovascular disease participated in the study voluntarily, which were allocated into two equal groups (n=15) of premenopausal women (age, 47.7±1.3 years) and postmenopausal women (age, 56.8±1.5 years). …”
Get full text

Robot-Assisted Surgery for Endometrial Cancer Using KangDuo versus Da Vinci Systems: A Retrospective Comparative Study by Liu T, Ma L, Wang Y, Wang B, Xu Y, Gao Y, Yu G, Gao J, Chen J

“…This retrospective comparative study aimed to evaluate the efficacy, safety, and functional outcomes of two robotic systems—Kangduo (KD-RAS) and Da Vinci (DV-RAS)—in the treatment of EC.Methods: This study included patients with stage T1 EC who underwent robotic-assisted surgery using either the Kangduo or Da Vinci system at Harbin Medical University Cancer Hospital. …”
Get full text

Ancient Medicinal Insect Steleophaga Plancyi (Boleny)-Derived Extracellular Vesicle-Like Particles Enhances Autophagic Activity to Promote Osteogenic Differentiation via Melatonin... by Lu J, Chen J, Jiang Y, Liu Y, Yu S, Shi Z, Chen P, Lin H, Li P

“…Steleophaga plancyi (Boleny) (SP), a component of traditional Chinese medicine, is known to enhance bone health, but the molecular mechanisms behind its osteoprotective effects are not well understood.Methods: We isolated extracellular vesicle (EV)-like particles from SP (SP-EVLP) using differential velocity centrifugation and investigated their effects on human bone marrow stromal cells (hBMSCs) in vitro. …”
Get full text

Injectable Polyhydroxyalkanoate-Nano-Clay Microcarriers Loaded with r-BMSCs Enhance the Repair of Cranial Defects in Rats by Ci H, Jie J, Zhang G, Wu L, Wang Z, Sun J

“…Open porous microspheres, characterized by their high specific surface area and osteo-inductive properties, offer an optimal microenvironment for cell ingrowth and efficient ossification, potentially accelerating bone regeneration.Materials and Methods: An in vitro investigation was conducted to assess the physicochemical properties, porosity, and biocompatibility of PHA-nano-clay open porous microspheres. …”
Get full text

Evaluation of the Anti-inflammatory Effect of Aqueous Extract of Pistacia atlantica Gum in an Experimental Model of Ulcerative Colitis by Shabnam Bahrami, Nahid Babaei, Hadi Esmaeili Gouvarchin Ghaleh, Jaleh Mohajeri Borazjani, Mahdieh Farzanehpour

“…This study aimed to assess the anti-inflammatory effects of the aqueous extract of Pistacia atlantica gum in an experimental model of ulcerative colitis. Materials and Methods: In this study, 20 male BALB/c mice were assigned to four equal groups. …”
Get full text

Сomparative evaluation of different soy protection schemes by V. Sergienko, O. Shita

“…Evaluate the effectiveness of various soybean protection schemes using preventive measures for seedlings and control measures during the growing season. Methods. Field, phytopathological, herbological, mathematical and statistical. …”
Get full text