Network Pharmacology Combined With Metabolomics Reveals the Mechanism of Yangxuerongjin Pill Against Type 2 Diabetic Peripheral Neuropathy in Rats by Jin R, Pei H, Yue F, Zhang X, Zhang Z, Xu Y, Li J

“…Pharmaceutical Factory, Beijing, 100079, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yi Xu; Jinsheng Li, Beijing Tongrentang Technology Development Co., Ltd. …”
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Cardioprotective effects of CoQ10 in pediatric patients with lysosomal storage disorders by Yasmine Abuzaid, Ghada Abdul Moemn Suliman, Osama Abd Rab El Rasool Toulba, Ahmed Abd El Basset Abo Elezz, Alshimaa Badraldeen, Heba Dawoud

“…The aim of this study: was to study the possible effects of Coenzyme Q10 as a cardioprotective and an antioxidant drug in patients with LSDs. Methods This study was a prospective case-control study conducted on 30 patients with LSDs and an equal number of healthy subjects of matched age and sex served as a control group at the unit of Medical Genetics and inborn errors of metabolism at the Pediatric Department of Tanta University Hospital. …”
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Phantom-based training of ultrasound-guided breast biopsy in medical education: a randomized controlled trial comparing handheld and high-end ultrasound by Barbara Greiner, Michael Akers, Florian Zeman, Andrea Goetz, Moritz Brandenstein, Christian Stroszczynski, Ernst Michael Jung, Simone Hammer

“…The objective of this study was to investigate if guidance by HUD is on par with a cart-based high-end ultrasound scanner (HEUS) regarding performance times and success rates in video- and phantom-based training of novices in US-guided freehand breast biopsy. Methods 32 medical students without any experience in performing US-guided percutaneous biopsies, who had previously completed a standardized diagnostic US training program, were randomized into either a HUD-group (n = 16) or a HEUS-group (n = 16). …”
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Impact of climate change on the potential global prevalence of Macrophomina phaseolina (Tassi) Goid. under several climatological scenarios by Peter F. Farag, Dalal Hussien M. Alkhalifah, Shimaa K. Ali, Aya I. Tagyan, Wael N. Hozzein

“…Macrophomina phaseolina (Tassi) Goid. is one of the most pervasive and destructive soil-borne fungus that threatens food security, so predicting its current and future distribution will aid in following its emergence in new regions and taking precautionary measures to control it.MethodsThroughout this work, there are about 324 records of M. phaseolina were used to model its global prevalence using 19 environmental covariates under several climate change scenarios for analysis. …”
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Adherence to ADA Clinical Guidelines in Type 2 Diabetes Management in Public Health Clinics in Palestine by Abukhalil AD, Muhanna SA, Madi MN, Al-Shami N, Naseef HA, Rabba AK

“…Adherence to established guidelines is essential for effective management of this metabolic disease.Objective: This study aimed to evaluate the current practices of physicians in Palestine regarding their adherence to ADA guidelines for type 2 diabetes management.Methods: A retrospective, cross-sectional, multicenter study was conducted by reviewing patients’ medical records. …”
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Development of a Nomogram Integrating Modified Inflammation-Based Indexes for Predicting Overall Survival in Pancreatic Cancer: A Retrospective Study by Qin D, Huang K, Yao Z, Xi P, Jiang L, Wei R, Li S

“…Adjusting inflammation indices for liver function may enhance their clinical utility for predicting overall survival (OS) in PCA patients.Methods: Resected PCA cases were selected using specific criteria. …”
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Detecting early kidney injury due to host–virus interaction response in treatment-naive CHB—a pilot study by Puneet Gandhi, Kavita Peter, Subodh Varshney, Subodh Varshney, Mahendra Kumar Atlani, Mahendra Kumar Atlani, Kewal Krishan Maudar, Kewal Krishan Maudar

“…We aimed to evaluate and validate a set of protein biomarkers singularly and in combination for the early detection of subclinical kidney injury in patients with CHB naive to antiretroviral therapy.MethodsThis work is part of a prospective cross-sectional study for which 69 HBsAg-positive, treatment-naive patients with CHB with an equal number of age-matched healthy volunteers were considered. …”
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Digital Patient–Reported Cancer Symptom Management: Comparison of Black and White Participants by Mary Gullatte, Bridget Nicholson, Elizabeth Sloss, Natalya Alekhina, Ann Marie Moraitis, Eli Iacob, Gary Donaldson, Kathi Mooney

“…This secondary analysis compared engagement, satisfaction, and cancer symptom reduction benefits in Black and White participants utilizing an electronic capture of patient‐reported outcome (ePRO) reporting system, symptom care at home (SCH), throughout chemotherapy. Methods Participants undergoing cancer treatment at a comprehensive cancer center reported daily on the 11 common oncology symptoms via electronic patient reporting (ePRO) on a scale of 0–10. …”
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An Investigation into the Current Landscape, Challenges, and Training Imperatives of Clinical Research Among Anesthesiologists in China by Du Y, Chen R, Wu L, Chen Q, Yu T, Li H, Wang G

“…Yingjie Du,1,* Ruirong Chen,1,* Lili Wu,1 Quan Chen,2 Tiankuo Yu,1 He Li,1 Guyan Wang1 1Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Anesthesiology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guyan Wang, Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of China, Email guyanwang2006@163.comObjective: This study aimed to investigate the status of anesthesiologists in clinical research in China, identify challenges, and propose strategies to improve research quality and anesthesiology services.Materials and Methods: A cross-sectional online survey was conducted among registered clinical anesthesiologists in China from April to May 2023. …”
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Factors Influencing Early Diagnosis of Ruptured Abdominal Aortic Aneurysms: The Role of Neutrophils by Zhang J, He Z, Zheng L, He X, Li J, Zhang L

“…Jing Zhang,1,* Zhaopeng He,1,* Lihua Zheng,1,* Xinqi He,1 Jian Li,2 Lei Zhang1 1Department of General Surgery, Department of Vascular Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Department of Radiology, The First Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lei Zhang, Email 57002230@hebmu.edu.cnBackground: Currently, there is no effective and convenient indicator for the early differential diagnosis of ruptured abdominal aortic aneurysms (rAAAs) from unruptured abdominal aortic aneurysms (AAAs).Objective: The aim of this study was to explore indicators for the early differential diagnosis of rAAAs in a clinical setting.Methods: This case‒control study included 276 subjects within the last 5 years (220 patients with unruptured AAAs; 56 patients with rAAAs) in the initial analysis and 229 subjects (186 patients with unruptured AAA’s; 43 patients with rAAA’s) after subgroup analysis. …”
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Jackson–Vanik Amendment and Development of Soviet-American Relations in 1972-1975 by V. Yungblyud, D. Ilyin

“…Each of the parties involved regarded the Amendment differently: Soviet leaders saw it as a rude interference in the internal affairs of the USSR; Kissinger saw it as an untimely and too radical in form and methods attempt to transform the Soviet system; Jackson saw it as a good way to increase his popularity by exploiting a popular in the post-Vietnam era theme that was naturally consistent with American national values and traditions. …”
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The Effect of 3-Month Growth Hormone Administration and 12-Month Follow-Up Duration among Heart Failure Patients Four Weeks after Myocardial Infarction: A Randomized Double-Blinded... by Afshin Amirpour, Mehrbod Vakhshoori, Reihaneh Zavar, Hadi Zarei, Masoumeh Sadeghi, Behzad Yavari

“…They were randomly assigned equally to groups received 5 IU subcutaneous GH or placebo. …”
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D-Dimer/Platelet Ratio Predicts in-Hospital Death in Patients with Acute Type a Aortic Dissection by Zhao A, Peng Y, Luo B, Chen Y, Chen L, Lin Y

“…This study was aimed at the potential of the D-dimer to platelet count ratio (DPR) as a prognostic indicator of ATAAD.Patients and Methods: This study retrospectively analyzed ATAAD patients who were admitted to the Department of Cardiac Surgery, Fujian Medical University Union Hospital from January 2022 to April 2023. …”
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The impact of the number of aneurysms on the course of the acute period of subarachnoid hemorrhage in patients with multiple intracranial aneurysms by Yulia O. Solodovnikova, Anatoliy S. Son

“… Objective to determine the effect of the number of multiple intracranial aneurysms (MIA) on the course of the acute period of subarachnoid hemorrhage (SAH). Materials and methods: A cross-sectional retrospective study was conducted involving 92 patients in the acute phase of SAH due to the rupture of MIA. …”
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Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy by Ke C, Yu Y, Li J, Yu Y, Sun Y, Wang Y, Wang B, Lu Y, Tang M, Wang N, Chen Y

“…We aimed to identify the causal proteins and potential targets for Graves’ disease (GD) and Graves’ ophthalmopathy (GO) via systematic genetic analyses.Methods: Genome-wide association studies (GWASs) on the UK Biobank- Pharma Proteomics Project (UKB-PPP) collected 2923 Olink proteins from 54,219 participants. …”
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Electroacupuncture versus sham electroacupuncture in treating low anterior resection syndrome after rectal cancer surgery: Study protocol for a randomized controlled trial. by Zi-Yue Wang, Guang-Xia Shi, Yu Wang, Wei Pei, Ying-Chi Yang, Jing-Wen Yang, Xiao-Ya Wei, Jin-Ying Jia, Jian-Feng Tu, Cun-Zhi Liu

“…<h4>Study design and methods</h4>This multicenter, randomized, sham-controlled clinical trial will be carried out across the outpatient clinics of three tertiary medical centers in China. …”
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Predictors of perinatal mortality in emerging regions of Ethiopia: Evidence from EDHS 2016. by Fikreab Desta, Girma Beressa, Biniyam Sahiledengle, Telila Mesfin, Lemlem Daniel Baffa, Yordanos Sintayehu, Demisu Zenbaba, Daniel Atlaw, Lillian Mwanri

“…Therefore, this study aimed to assess the factors that contribute to perinatal mortality rate in emerging region (Afar, Gambela, Somali, and Benishangul Gumuz) of Ethiopia's.<h4>Methods</h4>This study relied on data from the 2016 Ethiopian Demographic and Health Survey (EDHS). …”
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The Combination of D-TACE-HAIC, Lenvatinib, and PD-1 Inhibitors Shows Significant Clinical Efficacy in Patients with Unresectable Hepatocellular Carcinoma by Wu Y, Zhu J, Zhang H, Xia N

“…Yintao Wu,&ast; Jianyong Zhu,&ast; Hong Zhang, Nianxin Xia Senior Department of Hepato-Pancreato-Biliary Surgery, the First Medical Center of PLA General Hospital, Beijing, 100853, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Nianxin Xia, Senior Department of Hepato-Pancreato-Biliary Surgery, the First Medical Center of PLA General Hospital, Beijing, 100853, People’s Republic of China, Email doctorxnx@163.comPurpose: This study was developed to compare the efficacy of combined D-TACE-HAIC + lenvatinib + PD-1 inhibitor treatment to that of TACE + sorafenib treatment for patients with intermediate and advanced HCC.Patients and Methods: Here, a retrospective analysis of patients with unresectable HCC who underwent transarterial chemoembolization (TACE) from March 2018 to March 2022 at the our hospital was conducted. …”
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Health behavior and disease self-management indicators in patients with cardiovascular diseases using a health app: Findings from an RCT by Sonia Lippke, Luisa Korte, Vinayak Anand Kumar, Andreas Fach, Tiara Ratz

“…Based on a multiple behavior change theory, an intervention in the form of a digital health application (app) was evaluated in a pilot trial, testing the following hypotheses (H): H1: Health behaviors (physical activity, sitting) and disease self-management (self-care maintenance, self-care confidence) are closely related; H2: changes in health behaviors and disease self-management indicators over time (T0 to T1) are more pronounced in the intervention group (IG, app users) than in the control group (CG); H3: within the IG, changes in systolic and diastolic blood pressure indicate a positive trajectory.MethodsA 12-week randomized controlled trial (RCT) was conducted with two measurement points. …”
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Mortality trends from 2003 to 2009 among adolescents and young adults in rural Western Kenya using a health and demographic surveillance system. by Penelope A Phillips-Howard, Frank O Odhiambo, Mary Hamel, Kubaje Adazu, Marta Ackers, Anne M van Eijk, Vincent Orimba, Anja van't Hoog, Caryl Beynon, John Vulule, Mark A Bellis, Laurence Slutsker, Kevin deCock, Robert Breiman, Kayla F Laserson

“…<h4>Background</h4>Targeted global efforts to improve survival of young adults need information on mortality trends; contributions from health and demographic surveillance system (HDSS) are required.<h4>Methods and findings</h4>This study aimed to explore changing trends in deaths among adolescents (15-19 years) and young adults (20-24 years), using census and verbal autopsy data in rural western Kenya using a HDSS. …”
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