Evaluation of virtual non-contrast detector-based spectral CT images in comparison to true unenhanced images in 20 rabbits by Manon Mikić, Philipp Lietz, Julie-Ann Dierig, Sebastian Meller, Michael Pees, Kristina Merhof

“…Our hypothesis were that the VNC series would be comparable to TUE series and that the quality of the VNC images would be equal to or even superior to the native images.MethodsAttenuation values of VNC and TUE series were assessed using a two one-sided t-test (TOST) and the signal-to-noise ratio was calculated for each ROI in the different series. …”
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Deep Learning Models for Predicting the Recurrence of Idiopathic Granulomatous Mastitis by Li L, Yang W, Jia H

“…This study aims to evaluate and compare the performance of different machine learning models, including logistic regression, random forest, and neural networks, in predicting IGM recurrence using patient data.Methods: A retrospective analysis was conducted on 212 patients diagnosed with IGM. …”
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Clinical characteristics of postmenopausal women with endometrial polyps by E. G. Kobaidze, Y. N. Matveeva, E. V. Shirinkina, N. V. Statnykh, N. M. Pirozhnikova

“…The issues of rise in incidence and malignant transformation of endometrial pathology along with elevating proportion of postmenopausal women in global population remain relevant.Aim: to evaluate clinical and laboratory data of postmenopausal patients with endometrial polyp.Materials and Methods. There were enrolled 156 cases of morphologically verified endometrial polyp; the age of the study patients averaged 61.39 ± 7.78 years. …”
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Model-Informed Precision Dosing of Levamlodipine Besylate in Smoking Patients by Li G, Guan Y, Yang Y, Xiang Q, Chen S, Shao J, Chen Y, Yu X

“…Using models to promote rational and accurate medication dosing in smoking patients when administered as initial monotherapy.Methods: A prospective study (NCT05126381) enrolled 43 patients receiving levamlodipine monotherapy. …”
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Multiculturalism, prejudice, and teachers’ expectations for the acculturation strategies of the refugee students by Petroula Giannousi

“…The aim of this study is to assess teachers’ attitudes toward intercultural relations in the school context, focusing on their views on multiculturalism, their prejudices toward refugees, and their expectations regarding the acculturation of refugee students. Research methods: This study employs a quantitative methodology and a synchronic research design. …”
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DINAMIKA TARI REMO BOLET SANGGAR RAFF DANCE COMPANY INDONESIA : SEBUAH KAJIAN STRUKTUR GERAK TARI by R. indri yanto indriyanto, Lia Ayu Agustin Lia Ayu Agustin

“…This research aims to find out and describe how to study the dynamics of the Remo Bolet Dance movements using qualitative research methods with a structural approach as well as an ethical and emic approach. …”
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Development and Testing a New Online Dynamic Nomogram for Contrast-Induced Acute Kidney Injury in Elderly Patients with ST-Segment Elevation Myocardial Infarction by Jin J, Ding J, Zhang X, Wang L, Zhang X, Li W, Li S

“…However, contrast-induced acute kidney injury (CI-AKI), the third most common cause of hospital-acquired renal failure, remains a critical complication of PCI.Objective: To develop a machine learning model predicting CI-AKI risk in elderly patients with STEMI patients using clinical features.Methods: Data from 2120 elderly patients with STEMI treated with PCI at Xuzhou Medical University Affiliated Hospital (2019– 2023) were used for model development and testing. …”
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Effect of Donor Sperm on Quality of Life in Patients with Severe Oligoasthenosperm After ICSI Failure by Wang K, Xu Y, Qin N, Guo Y, Bai J, Li Z

“…Ke Wang,1– 3,* Yan Xu,2,3,* Ningxin Qin,1 Yi Guo,1 Jie Bai,3 Zheyuan Li4 1Center of Reproductive Medicine, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China; 2Department of Nursing, Shanghai Sanda University, Shanghai, 201209, People’s Republic of China; 3School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China; 4Intensive Care Unit, Zhongshan Hospital, Fudan University, Shanghai, 200032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ningxin Qin, Email ningxinqin@51mch.comObjective: To explore the effects of donor sperm on reproductive quality of life, sleep quality and erectile function in patients with severe oligoasthenospermia after the failure of intracytoplasmic sperm injection (ICSI), and to provide targeted reference for intervention.Methods: From January 2021 to December 2023, patients with severe oligoasthenospermia who received assisted pregnancy treatment in Obstetrics and Gynecology Hospital Affiliated to Tongji University were selected as the study objects. …”
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Continuous Anlotinib Combined with Oral Vinorelbine has Shown Anti-Tumor Efficiency in Refractory HER2 Negative Advanced Breast Cancer by Huang JY, Zhang Y, Du CW

“…Jia-Yi Huang,1,* Yan Zhang,2,* Cai-Wen Du1 1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, Guangdong, 518116, People’s Republic of China; 2Department of Emergency, Shenzhen Longhua District People’s Hospital, Shenzhen, Guangdong, 518109, People’s Republic of China*These authors contributed equally to this workCorrespondence: Cai-Wen Du, Email dusumc@aliyun.comPurpose: To explore the efficacy and safety of continuous administration of anlotinib combined with oral vinorelbine in refractory human epidermal growth factor-2 (HER2) negative advanced breast cancer (ABC).Patients and Methods: This retrospective study included 41 HER2 negative ABC patients who received anlotinib (8mg orally per day without interruption) plus oral vinorelbine during November 2019 and February 2023. …”
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Early Warning of Axillary Lymph Node Metastasis in Breast Cancer Patients Using Multi-Omics Signature: A Machine Learning-Based Retrospective Study by Ke Z, Shen L, Shao J

“…Therefore, additional research is needed to accurately predict ALN metastasis before surgery and construct predictive models to assist in surgical decision-making and optimize patient care.Methods: We retrospectively analyzed the clinical data, radiomics, and pathomics of the patients diagnosed with breast cancer in the Breast Cancer Center of Hubei Cancer Hospital from January 2017 to December 2022. …”
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Chronic depression treated successfully with novel taping therapy: a new approach to the treatment of depression by Han CH, Hwang HS, Lee YJ, Lee SN, Abanes J, Lee BH

“…We report cases where patients with severe depressive symptoms were successfully treated by taping therapy, a new approach.Methods: In case 1, a patient was taking several psychiatric medications for 10 years and admitted often to the psychiatric hospital with a leaning head, flexible legs, and nearly closed eyes; in case 2, a patient after a hysterectomy complained with heart palpitations, depressive- and anxiety-like behaviors, insomnia, and gastrointestinal problems; and in case 3, a patient with complaints of adverse effects from antidepressant medications had suicidal thoughts frequently. …”
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A PROSPECTIVE, OBSERVATIONAL STUDY OF ADVERSE REACTIONS TO DRUG REGIME FOR MULTI-DRUG RESISTANT PULMONARY TUBERCULOSIS IN CENTRAL INDIA. by Dr. Rohan C. Hire, Dr. A. S. Kale, Dr. G. N. Dakhale, Dr. Nilesh N. Gaikwad

“…Abstract Objective: 1) To assess the adverse drug reactions of second line anti-tubercular drugs used to treat Multi-drug resistant Tuberculosis (MDR TB) in central India on the basis of causality, severity and avoidability scales. 2) To study the relationship of type of MDR TB (primary or secondary) and presence of diabetes mellitus (DM) with mean smear conversion time. Material and Methods: A prospective, observational study was carried out on diagnosed multidrug resistant tuberculosis patients enrolled for DOTS‑Plus regimen at TB and Chest Disease Department from January to December 2012. …”
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Persistent oral health inequality in children—repeated cross-sectional studies in 2010 and 2019 by Caroline Blomma, Thomas Davidson, Elisabeth Wärnberg Gerdin, Mats Bågesund, Johan Lyth

“…The aim was therefore to analyse the association between 6-year-olds´ caries prevalence and socioeconomic variables at family and residential area levels in 2010 and 2019 as well as potential differences in the association between 2010 and 2019. Methods The study design is an epidemiological registry-based, repeated cross-sectional study based on caries data (grouped as 0, 1–3 and > 3 dmft) for the population of 6-year-olds in 2010 (n = 4,408, 95% coverage) and 2019 (n = 5,199, 94% coverage) in a Swedish region. …”
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Immunoglobulin G N-Glycosylation and Inflammatory Factors: Analysis of Biomarkers for the Diagnosis of Moyamoya Disease by Zan X, Liu C, Wang X, Sun S, Li Z, Zhang W, Sun T, Hao J, Zhang L

“…This research aimed to evaluate the diagnostic efficacy of IgG N-glycosylation for MMD.Methods: Ultra-high-performance liquid chromatography (UPLC) was employed to examine the properties of IgG N-glycans in blood samples from 116 patients with MMD and 126 controls, resulting in the quantitative determination of 24 initial glycan peaks (GP). …”
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Reversing Pathology in an Aggravated Fabry Mouse Model Using Low-Dose Engineered Human Alpha-Galactosidase A AAV Gene Therapy by Wanida Ruangsiriluk, Mugdha Deshpande, Natalia Boukharov, Girija Rajarshi, Shreya Mukherji, Shipeng Yuan, Jennifer Wiseman, Nancy Chen, Eric Park, Hyelim Cho, Rizwana Islam

“…Efficacy of the Eng-C AVV GT was equal to or greater than the efficacy of the higher doses of the AAV GT with native α-GAL. …”
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Hypotensive Effects of Statins: A Rapid Review by Smruti Besekar, Sangita Jogdand, Satyawan Singh Patel

“…Aim: To explore the hypotensive effects of statins on BP and to determine whether they can serve as an adjunct to antihypertensive drugs. Materials and Methods: This study was conducted in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-analysis Statement (PRISMA-S) guidelines. …”
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Serum Glucose-Phosphate Ratio on Admission as a Potential Biomarker for Severity, Functional Outcome, and Recurrence in Acute Ischemic Stroke by Li J, Ma W, Tang W, Yang K, Gu H, Shi J, Chen F, Xu C, Gu S, Wang Y

“…Therefore, this prospective study aimed to investigate the association between admission serum glucose-phosphate ratio and the severity and 1-year clinical outcome of AIS.Methods: All the patients with AIS were enrolled from the Third China National Stroke Registry III. …”
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Effect of Jian-Pi-Zhi-Dong Decoction on striatal glutamate and γ-aminobutyric acid levels detected using microdialysis in a rat model of Tourette syndrome by Zhang W, Wei L, Yu W, Cui X, Liu X, Wang Q, Wang S

“…This study evaluated the effect of JPZDD on glutamate (Glu) and γ-aminobutyric acid (GABA) and their receptors in a TS rat model.Materials and methods: Rats were divided into four groups (n=12 each). …”
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Exosomes from Adipose-Derived Mesenchymal Stromal Cells Prevent Medication-Related Osteonecrosis of the Jaw by Inhibiting Macrophage M1 Polarization and Pyroptosis by Zheng Y, Wang X, He Y, Chen S, He L, Zhang Y

“…In this study, our aim was to explore the mechanisms of exosomes derived from adipose-derived mesenchymal stromal cells (ADSCs) in preventing MRONJ by focusing on macrophage M1 polarization and pyroptosis.Methods: The MRONJ model was established by the administration of zoledronate and tooth extraction. …”
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Fumarate Hydratase Restrains mtDNA Attenuates LPS-Induced Acute Lung Injury Through cGAS-STING Pathways by Jiang Z, He R, Zhong Y, Liu B, He Z

“…Fumarate hydratase (FH), a key enzyme catalyzing fumarate-to-malate conversion in the TCA cycle, is implicated in macrophage inflammatory responses, but its specific role in ALI remains unclear.Methods: We employed FHIN1 to assess its regulatory effects in LPS-induced ALI models. …”
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