Intravesical Tumor-Selective Mucoadhesive Hydrogel for Effective Chemotherapy In Murine Model by Zheng B, Chen Z, Sun L, Quan J, Wei J, Huang B, Zhang D, Zhang P, Zhuo Y

“…Consequently, an effective drug delivery system must possess both tumor-targeting and adhesion properties to overcome these limitations.Methods: In this study, we investigated a tumor-selective hydrogel as a potential vehicle for BCa treatment. …”
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Inter-laboratory harmonization of microsphere immunoassays for SARS-CoV-2 antibody detection in contrived dried blood spots and oral fluids by Kate L. DeRosa, Nora Pisanic, Kate Kruczynski, Christopher D. Heaney, Linda M. Styer, Nicholas J. Mantis

“…Furthermore, assays were transferred between labs, including methods and reagents, and a subset of cDBS and cOF samples (n = 52) were tested. …”
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Disorders of esophageal clearance in gastroesophageal reflux disease and option of their treatment by O. A. Storonova, A. S. Trukhmanov, N. L. Dzhahaya, V. T. Ivashkin

“…To estimate esophageal clearance in patients with reflux-esophagitis (RE) and its changes at intake of «Smecta®» in standard dose. Material and methods. Overall 30 patients whose symptoms included heartburn (100%), burning chest pain (70%), belching (30%) were enrolled in original study. …”
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Couples and parenting dynamics during Covid-19 pandemic: A systematic review of the literature. by Maria Leonor Sentieiro, Luana Cunha Ferreira, Mariana Pires de Miranda, Beatriz Araújo Vitória

“…Within 381 articles, 58 studies met the inclusion criteria, which 50 were quantitative, four qualitative, and four mixed methods studies. A qualitative thematic analysis of the reviewed articles identified 12 categories that were organized by stress sources, mediators, and outcomes. …”
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Epidemiological Changes in Hospitalized Bronchiolitis in Children Under 2 Years of Age in Hangzhou Before and After COVID-19 Restriction Easing by Xu X, Chen X, He J, Su L, Tong X, Sun Y, Huang S, Bai G, Chen Z

“…This study aimed to analyze the changes in the viral etiology of bronchiolitis in Hangzhou during the COVID-19 restriction period (2022) compared to the period following the easing of restrictions(2023).Methods: This study collected data on patients under 2 years of age who were admitted for bronchiolitis to the Department of Pulmonology at the Children’s Hospital, Zhejiang University School of Medicine (Hangzhou) from January, 1, 2022, to December 31, 2023. …”
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Biomechanical evaluation of novel construct for stabilizing subcapital femoral neck fractures: a synthetic bone model by Anjan R. Shah, Miguel A. Diaz, Douglas L. Cerynik, Blake Schultz

“…The objective was to evaluate the biomechanical performance of a novel femoral neck fracture fixation device by comparing to a clinically relevant construct using commercially available cannulated screws. Methods Twelve Sawbones femurs were equally divided into two groups where Group I was instrumented with a new fixation system consisting of two partially threaded cannulated screws and a cross-screw and Group II was instrumented with three partially threaded cannulated screws. …”
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DNA-PKcs Dysfunction Enhances the Antitumor Activity of Radioimmunotherapy by Activating the cGAS-STING Pathway in HNSCC by Chen L, Lin J, Wen Y, Guo ZQ, Lan B, Xiong J, Chen CB, Chen Y

“…The potential improvement of radioimmunotherapy by inhibiting the DDR pathway is still unclear.Methods: The effectiveness of different treatments on tumor growth and survival was tested using the C3H/HeN mouse tumor model. …”
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When midwives ask permission to discuss weight with pregnant women with high body weight: a qualitative study by Sofie Gyrup, Anne-Sofie Kortegaard, Sissel Due Jensen, Pernille Andreassen, Dorte Hvidtjørn

“…Methods We observed nine midwifery consultations and, by way of purposive sampling, interviewed six pregnant women with high body weight, while nine midwives participated in two focus group interviews. …”
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Developing an Algorithm for Detecting Suspicious Trades in Tehran Stock Exchange Based on Spoof Trading Model by Reza Tehrani, Saeed Fallahpour, Hamid Nouralidokht

“…The ultimate goal of this paper is to help the “Securities and Exchange Organization” (SEO) of Iran to reform market regulations in order to prevent the occurrence of suspicious trades in the market. Methods: This research relies on price data placed by investors in the market. …”
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Deficits in prosodic speech-in-noise recognition in schizophrenia patients and its association with psychiatric symptoms by Shenglin She, Bingyan Gong, Qiuhong Li, Yu Xia, Xiaohua Lu, Yi Liu, Huawang Wu, Chao Wu, Yingjun Zheng

“…Both participant groups had equal SR between the neutral and happy prosody conditions. …”
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Dynamics of Myopia Progression in Ghana—Evidence From Clinical Practice: A Retrospective Cohort Study by Samuel Kyei, Godwin Avornyo, Randy Asiamah, Samuel B. Boadi‐Kusi, Michael Agyemang Kwarteng

“…ABSTRACT Background and Aim To investigate the pattern of progression of myopia among a Ghanaian clinical cohort. Methods A retrospective cohort analysis of a clinical data set of all healthy myopic participants attending a tertiary eye care center was performed. …”
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The Association of Latent Tuberculosis Infection with Air Pollutant Exposure, Meteorological and Other Factors: A Retrospective Study in Eastern China of College Students by Qiu B, Xu Z, Miao R

“…This study aimed to assess the association of meteorological factors, air pollutant indicators, and other factors with LTBI among college students.Methods: We selected 5,193 freshmen randomly who originated from key tuberculosis areas in nine colleges in Nanjing. …”
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Body Image and Negative Emotions in Chinese Deaf and Hard-of-Hearing College Students: The Mediating Role of Core Self-Evaluation and the Moderating Role of Self-Compassion by Bu X, Zhang Y, Zeng T, Zhou L, Ma H, Du Y

“…The present study aimed to explore the impact of body image on negative emotions as well as the mediating role of core self-evaluation and the moderating role of self-compassion by using a sample of DHH college students.Materials and Methods: A sample of 357 Chinese DHH students completed the measures of body image, core self-evaluation, self-compassion, depression, and anxiety. …”
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Latent Health Status Trajectories in Individuals With New or Worsening Claudication Symptoms by Scott Grubman, Gaëlle Romain, Jacob Cleman, Lindsey Scierka, Carmen Pajarillo, Jonathan Kluger, Carlos Mena‐Hurtado, Kim G. Smolderen

“…We aimed to determine health status trajectories and explore baseline factors associated with treatment nonresponsiveness. Methods Data were derived from the PORTRAIT (Patient‐Centered Outcomes Related to Treatment Practices in Peripheral Arterial Disease: Investigating Trajectories) registry of patients with claudication symptoms presenting to vascular specialty clinics across the United States, Australia, and Netherlands. …”
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Bed Partners’ Perspectives and Sleep Quality After Hypoglossal Nerve Stimulation Therapy for Obstructive Sleep Apnea by Seifen C, Ludwig K, Ruckes C, Matthias C, Gouveris H

“…We aimed at evaluating the bed partner’s perspective on HGNS therapy.Methods: In a cross-sectional exploratory prospective study (Clinical Trial Registration: DRKS00030554), 33 consecutive bed partners of patients treated with a unilateral, respiratory-coupled HGNS device in a tertiary medical center completed a 23-item custom-made questionnaire with questions that addressed the bed partner’s perceptions and their satisfaction with HGNS therapy.Results: Bed partners reported that the patients were more comfortable with HGNS therapy (97.0%) compared to PAP therapy, their own sleep quality was better (90.9%) and their sexual partnership was equivalent in 69.0% and better in 27.3%. …”
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Cost-effectiveness analysis of penpulimab plus carboplatin-paclitaxel as first-line treatment for metastatic squamous non-small-cell lung cancer in China by Luwei Wang, Jiasheng Chen, Lihui Lin, Xiaowei Huang

“…CP from the Chinese healthcare perspective. Methods A three-state Markov model was developed to evaluate the cost-effectiveness of PEN-CP as a first-line treatment for metastatic sqNSCLC. …”
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Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial. by A David Smith, Stephen M Smith, Celeste A de Jager, Philippa Whitbread, Carole Johnston, Grzegorz Agacinski, Abderrahim Oulhaj, Kevin M Bradley, Robin Jacoby, Helga Refsum

“…<h4>Objective</h4>To determine whether supplementation with B vitamins that lower levels of plasma total homocysteine can slow the rate of brain atrophy in subjects with mild cognitive impairment in a randomised controlled trial (VITACOG, ISRCTN 94410159).<h4>Methods and findings</h4>Single-center, randomized, double-blind controlled trial of high-dose folic acid, vitamins B(6) and B(12) in 271 individuals (of 646 screened) over 70 y old with mild cognitive impairment. …”
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Folate-Functionalized CS/rGO/NiO Nanocomposites as a Multifunctional Drug Carrier with Anti-Microbial, Target-Specific, and Stimuli-Responsive Capacities by Obireddy SR, Ayyakannu A, Kasi G, Sridharan B, Lai WF, Viswanathan K

“…CS, rGO, and NiO nanoparticles are selected due to their pH-responsiveness, large surface area, and ROS generating-capacity, respectively.Methods: The CS/rGO/NiO nanocomposites (NCs) are synthesized using a solvothermal approach. …”
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Intrinsic Links Between Non-Suicidal Self-Injury and Sleep Quality and Cytokines: A Network Analysis Based on Chinese Adolescents with Depressive Disorders by Zhang Y, Suo X, Wang X, Xu J, Xu W, Pan L, Gao J

“…This study aimed to assess the interactions between NSSI and sleep quality and cytokines and explore the association of these factors with cognitive flexibility.Methods: A cross-sectional survey was conducted from January 2022 to September 2024 in Qingdao, China. …”
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Titanium Dioxide Nanoparticle Exposure Provokes Greater Lung Inflammation in Females Than Males in the Context of Obesity by Jeong JS, Jegal H, Ko JW, Kim JW, Kim JH, Chung EH, Boo SY, Lee SH, Lee GW, Park SM, Choi MS, Han HY, Kim TW

“…This study investigated the effect of pre-existing obesity on respiratory toxicity and explored whether sex differences exist in the response to titanium dioxide nanoparticles (TiO2-NPs), a component of air pollutants.Methods: Male and female mice were fed a normal diet (ND) or a high-fat diet (HFD) for 26 weeks and then intratracheally instilled with TiO2-NPs at concentrations of 0, 0.1, 0.2, and 0.4 mg/50 μL on days 1, 4, 6, 9, 11, and 13. …”
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