Efficacy and Comfort Level with the Non-Sliding Lingual Orthodontic Technique (BRIUS™) Versus Labial Full Fixed Appliances: A Pilot Randomized Controlled Clinical Trial by Mohammed Hussain Alzainal, Stephen Warunek, David A. Covell, William Tanberg, Aron Aliaga-Del Castillo, Lucia Cevidanes, Thikriat Al-Jewair

“…<b>Introduction:</b> This pilot two-arm, parallel group, randomized clinical trial aimed to compare the efficacy of tooth movement and patient comfort during orthodontic leveling and alignment with the BRIUS™ lingual system (BR) versus labial full fixed appliances (LFFAs). <b>Methods:</b> Patients in the permanent dentition with mild to moderate crowding were recruited at the University at Buffalo and randomly assigned into the BR group (seven patients) or LFFAs group (six patients). …”
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Effect of Metformin on Handgrip Strength, Gait Speed, Myostatin Serum Level, and Health-related Quality of Life: A Double Blind Randomized Controlled Trial among Non-diabetic Pre-f... by Purwita Wijaya Laksmi, Siti Setiati, Tirza Z Tamin, Pradana Soewondo, Wasilah Rochmah, Nafrialdi Nafrialdi, Joedo Prihartono

“…One-hundred-twenty subjects who met the research criteria were randomized and equally assigned into 3 x 500 mg metformin or placebo group. …”
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Evaluation of Physical and Mental Health in Adults Who Underwent Limb-Lengthening Procedures with Circular External Fixators During Childhood or Adolescence by Alessandro Depaoli, Marina Magnani, Agnese Casamenti, Marco Ramella, Grazia Chiara Menozzi, Giovanni Gallone, Marianna Viotto, Gino Rocca, Giovanni Trisolino

“…This study evaluated the Health-Related Quality of Life (HRQoL) and physical functioning of adults who underwent unilateral limb lengthening with circular external fixators (EFs) in childhood. Methods: Fifty patients treated at a median age of 14.9 years completed the Short Form 36 (SF-36) and Stanmore Limb Reconstruction Score (SLRS) questionnaires in adulthood, with a median follow-up of 8.9 years. …”
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Analysis results of surgical treatment and chemoradiotherapy with assessment of prognostic factors in localy advanced laryngeal cancer by Z. A.‑G. Radzhabova, M. A. Kotov, M. M. Girshovich, O. I. Ponomareva, E. V. Kostromina, M. A. Radzhabova, A. S. Mitrofanov, V. V. Klimenko, E. V. Levchenko

“…The study objective – to analyze the treatment results and prognostic factors of survival in patients with locally advanced laryngeal cancer who received surgical treatment and chemoradiotherapy.Materials and methods. The retrospective study included patients with locally advanced laryngeal cancer treated at the N. …”
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Investigating the Knowledge of General Dental Students and Residents Regarding Practical Self-Assessment Skills by Fatemeh Sadat Sajadi, Zahra Salari, MohadeseSadat TabatabaeiRad, Ali Abedi, Reyhaneh Aftabi

“…Background: Self-assessment (SA) means assessing or judging efficiency, and identifying strengths and weaknesses to improve learning outcomes.Objectives: The present study aims to investigate the knowledge, and attitude of the students of Kerman Dental Faculty regarding practical self-assessment skills.Methods: This cross-sectional descriptive-analytic study included 220 residents, and general students of Kerman Faculty of Dentistry. …”
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Molecular profile of Epstein–Barr virus in representatives of four ethnic groups of Russia: virus types, <i>LMP1</i> gene variability and malignancies by K.  V. Smirnova, A. K. Lubenskaya, N. B. Senyuta, T. E. Dushenkina, V. E.  Gurtsevitch

“…To study EBV-1 and EBV-2 in representatives of four ethnic groups of Russia, sequence analysis of the LMP1 oncogene in virus isolates, and search for a correlation between the types of EBV and the incidence of certain types of malignant tumors in four ethnic groups.Materials and methods. From total DNA obtained from oral washings of Adygeans, Kalmyks, Tatars and Slavs, representatives of 3 Russian republics and the Moscow region, EBV DNA was amplified; its presence and concentration were analyzed by nested PCR, and each product was examined for the virus type and LMP1 variant. …”
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JAK2V617F-positive clonal hematopoiesis of indeterminate potential in pregnant women by I. A. Olkhovskiy, J. G. Garber, A. S. Gorbenko, M. A. Stolyar, O. M. Miller, E. S. Kostina, Yu. Yu. Komarovskiy, V. V. Potilitsina

“…Aim: to assess the prevalence of V617F somatic mutation of the JAK2 gene in pregnant women.Materials and methods. This non-interventional study was performed in the framework of routine clinical practice and included 1532 samples of venous blood from pregnant women who applied for medical assistance at Krasnoyarsk Regional Clinical Center for Maternal and Child Welfare. …”
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Apolipoprotein E dysfunction in Alzheimer’s disease: a study on miRNA regulation, glial markers, and amyloid pathology by Printha Wijesinghe, Hao Ran Li, Zhengyuan Ai, Matthew Campbell, Si Xuan Chen, Jeanne Xi, Wellington Pham, Wellington Pham, Joanne A. Matsubara, Joanne A. Matsubara

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Influence of preoperative variables on the 3-month functional outcomes of the Vivity extended depth-of-focus intraocular lens: a prospective case series by Giacomo Savini, Alice Galzignato, Catarina P. Coutinho, Jinhai Huang, Yue Wu, Piero Barboni, João Mendanha Dias, Filomena J. Ribeiro, Domenico Schiano-Lomoriello

“…Visual disturbances and spectacle independence were assessed with McAlinden and IOLSAT questionnaires, respectively. …”
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Comparison of retinal vascular abnormalities in the fellow eyes of children with Coats’ disease and normal subjects using ultra-widefield fundus fluorescein angiography by Shenshen Yan, Haixia Ji, Yuzhu Liu, Haicheng She, Haiying Zhou

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A novel mesothelioma molecular classification based on malignant cell differentiation by Jun Liu, Yifan Liu, Yuwei Lu, Wei Zhang, Jiale Yan, Bingnan Lu, Yuntao Yao, Shuyuan Xian, Donghao Lyu, Jiaying Shi, Yuanan Li, Xinru Wu, Chenguang Bai, Jie Zhang, Yuan Zhang

“…However, a molecular classification based on differentiated states of tumor cells remains void. Methods We performed dimensionality reduction analysis on the single-cell RNA sequencing profiles available from the GEO database, to visualize the cell types in MESO. …”
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Automated Assessment to Predict Lethal Arrhythmias in Brugada Syndrome: Significance of R' in Lead III by Daiki Shako, Satoshi Nagase, Naoya Kataoka, Toshihiro Nakamura, Satoshi Oka, Yuichiro Miyazaki, Akinori Wakamiya, Kenzaburo Nakajima, Nobuhiko Ueda, Tsukasa Kamakura, Mitsuru Wada, Kohei Ishibashi, Yuko Inoue, Koji Miyamoto, Takeshi Aiba, Kengo Kusano

“…This study aimed to examine predictive factors for SCA in BrS using automated ECG measurements. Methods In 270 patients with BrS, ECGs were recorded using the same electrocardiograph when a Type 1 ECG was initially observed. …”
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Liraglutide for idiopathic intracranial hypertension: a real‐world propensity score‐matched study by Ahmed Y. Azzam, Muhammed Amir Essibayi, Dhrumil Vaishnav, Mohammed A. Azab, Mahmoud M. Morsy, Osman Elamin, Adam Elswedy, Oday Atallah, Hana J. Abukhadijah, Adam A. Dmytriw, Amanda Baker, Deepak Khatri, Neil Haranhalli, David J. Altschul

“…We investigated the efficacy of liraglutide as an adjunctive therapy in IIH management. Methods We conducted a retrospective cohort study, analyzing adult patients with IIH. …”
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Bringing climate health conversations to frontline clinics: A qualitative post-intervention assessment of utilization of the Climate Resilience for Frontline Clinics Toolkit by Yi-Ting Hana Lee, Mingyue Ma, Caroline Sarpy, Casey Dai, Jinia Sarkar, Chelsea Heberlein, Theodore Miles, Caleb J. Dresser

“…The objectives of this study were to assess the utilization and challenges in the implementation of the toolkit in real-world clinic settings and to guide further development of clinic-based risk reduction resources. Methods: A qualitative, semi-structured interview and post-intervention assessment approach was used to interview 28 clinicians and staff from 15 clinics across six states. …”
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Therapeutic effect of two muscle strengthening programs in patients with patellofemoral pain syndrome. A randomized controlled clinical trial by Luisa Fernanda Prieto-García, Edgar Cortés-Reyes, Gilberto Lara-Cotacio, Lizeth Catherine Rodríguez-Corredor

“…The level of pain was measured using the Visual Analog Scale and the Kujala Anterior Knee Pain Scale. …”
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Evaluating the Effectiveness of Erector Spinae Block vs Local Infiltration in Enhancing Early Recovery Following Vertebroplasty: A Randomized Controlled Trial by Hariharan Subramanian, Sudhakaran Ramasamy, Yogadeepan Dhakshinamurthi, Muthu S Meignanaguru, Nandhakumar Murugesan, Ganesh R Shetty, Deepak Srinivasan

“…Erector spinae block, which provides segmental analgesia to the affected vertebrae, provides a novel approach to better patient experience in patients undergoing vertebroplasty. Materials and methods: The 42 patients enrolled in the study were split into two groups of 21 each: (1) Erector spinae plane (ESP) group—patients receiving erector spinae block before vertebroplasty and (2) L group—patients receiving local infiltration. …”
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Metabolic correlations between kidney and eye in a mouse model of oxygen-induced retinopathy and retinopathy of prematurity by Jie Sun, Guoming Zhang, Yulin Zhang, Xiaofeng Lu, Zixin Fan, Yuhang Yang, Lijun Dong, Hui Qi, Yinsheng Zhang, Xiaoyan Chai, Dongting Wu, Hetian Lei

“…Introduction Retinopathy of prematurity (ROP) is one of the leading causes of babies’ visual impairment and blindness. There is no effective prevention and treatment of ROP so far, and the shared genetic and developmental similarities among the brain, kidneys and retina may offer novel potential therapeutic approaches to ROP.Objectives The aim of this study is to explore a correlation of ROP patients and the renal, eye tissue of the mouse model of oxygen-induced retinopathy (OIR).Methods and analysis We used renal and vitreous untargeted/targeted metabolomics in OIR to conduct our study. …”
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Various classes of removable partial dentures: A study of prevalence among patients attending a dental and educational institute in Riyadh, Saudi Arabia by Nadia Al-Angari, Saeed Algarni, Anas Andijani, Abdulwahab Alqahtani

“…The aim was to determine the prevalence of various Kennedy classifications among patients attending clinics at the College of Dentistry at King Saud bin Abdulaziz University for Health Sciences and King Abdulaziz Dental Center, National Guard Health Affairs, who were seeking treatment for partial edentulism. Methods: An observational cross-sectional study was conducted by visualizing cast models for partially edentulous patients. …”
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A specific dual-mobility prosthesis design in trapeziometacarpal joint osteoarthritis by Giuseppe Rovere, Francesco Bosco, Alessio Cioffi, Fortunato Giustra, Francesco Liuzza, Lawrence Camarda

“…The aim of the study was to analyze the clinical, functional, and radiological outcomes and complications of a specific dual-mobility prosthesis for TMJ OA to support the correct hand surgeon decision. Methods: Between January 2019 and January 2022, a retrospective study was conducted on a consecutive series of 14 patients affected by TMJ OA and treated with the implantation of TOUCH® dual mobility TMJ prosthesis (KeriMedical Switzerland-HQ, Geneve, Switzerland). …”
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Comparative meta-analysis of TightRope vs. hook plate for acromioclavicular joint dislocation by Manuel Alejandro Villagrán-Luján, Alejandro Alarcon-Mendoza, Edgar Azael Perez-Gutierrez, Manuel Alberto Gutierrez-Moreno, Nadia Karina Portillo-Ortiz, Edmundo Berumen-Nafarrate

“…Objective: This study aims to compare the clinical and radiographic outcomes of the tight-rope system versus internal fixation with a hook plate for treating grade III-VI acute acromioclavicular dislocation. Methods: Relevant studies were identified by searching PubMed, Cochrane, and Google Scholar, from January 2017 to December 2023. …”
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