Clinical Characteristics of Neovascular Age-Related Macular Degeneration without Typical Drusen by Hiroyuki Kamao, Katsutoshi Goto, Kento Matsuno, Kenichi Mizukawa, Atsushi Miki, Junichi Kiryu

“…To evaluate the clinical characteristics of neovascular age-related macular degeneration (nAMD) patients without typical drusen. Methods. We retrospectively studied 165 eyes in 165 patients with treatment-naïve nAMD, including typical AMD and polypoidal choroidal vasculopathy (PCV). …”
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Coping with pain among adults with chronic tic disorders by Agnieszka Małek

“…The aims of this study were to assess tic-related pain, pain coping strategies and beliefs, and to investigate whether individuals experiencing pain seek professional help and how effective they perceive such interventions to be.MethodsA total of 76 participants diagnosed with GTS and CMTD participated in the study. …”
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Tolerability of Transperineal Prostate Biopsy Under Local Anaesthetic Using Pre-Emptive Over-the-Counter Analgesia: An Interventional Study in Patients with Abnormal Clinical Prost... by Shelley Ting-Li Wang, Yuxi Xu, Meredith J. Cheng, Anika Jain, Henry H. Woo

“…The objective of this study was to investigate the effects of over-the-counter analgesia on TP biopsies conducted under LA. <b>Methods</b>: This interventional single-centre study investigated 160 participants who undertook a TP biopsy under LA, with and without pre-emptive analgesia (1 g of paracetamol and 400 mg of ibuprofen). …”
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User-centered design and development of a web-based tool to support healthy feeding practices by parents of urban minority youth at risk for childhood obesity by Katrina F Mateo, Helene Vilme, Sandra Verdaguer, Abigail Fuqua, Kris Hoyt, Jacquelyn Davis, May May Leung

“…Thus, the objective of this manuscript is to provide valuable insights about the development of a parent–child web-based tool to promote healthy eating among preadolescents. Methods The tool development was an iterative process and comprised of two phases. …”
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Sounds of comfort: the impact of music therapy on labor pain and anxiety in primigravida women during vaginal delivery: a systematic review and meta-analysis by Rayyan Vaid, Areeba Fareed, Solay Farhat, Zeinab Hammoud, Muhammad Iqbal Asif, Sidhant Ochani, Mohammed Hammad Jaber

“…This systematic review and meta-analysis aim to comprehensively evaluate the impact of music therapy on labor pain in primigravida women during vaginal delivery. Methods Following PRISMA guidelines, a thorough literature search was conducted in Google Scholar, PubMed, and Cochrane Central Register of Controlled Trials up to November 2023. …”
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The Impact of Listening to Music During MRI-Fusion Prostate Biopsy Procedures on Pain and Anxiety Levels: A Randomized Controlled Trial by Çağrı Coşkun, Ender Cem Bulut, Serhat Çetin, Uğur Aydın, Bora Küpeli

“…This situation leads to the need to evaluate pain and anxiety. Methods: In a tertiary hospital in Turkey, 149 patients with suspicious lesions (PI-RADS ≥ 3 on MpMRI) who underwent transrectal CBx were included between May 2023 and August 2023. …”
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Using the LTO Network Level 1 Blockchain to Automate Inter-Organizational Business Processes by Khrypko Serhii L., Shcherbakov Serhii S.

“…The author explains the operation of a private event chain as an ad-hoc private blockchain that ensures the consistency of the process state between nodes. Methods of ensuring data privacy are discussed. The second part of the article is devoted to the global public blockchain LTO to confirm information from private event chains. …”
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Conversion hip arthroplasty in the treatment of adverse effects of proximal femoral fractures by A. N. Tsed, N. E. Mushtin, I. Yu. Zhukovets, A. K. Dulaev

“…Currently, there are no uniform algorithms for surgical tactics of conversion hip arthroplasty.The OBJECTIVE was to evaluate the mid-term results of conversion hip arthroplasty in patients with adverse effects of proximal femoral fractures.METHODS AND MATERIALS. A retrospective study of the treatment results of 58 patients who underwent conversion hip arthroplasty was conducted. …”
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Intraarticular leukocyte-poor platelet-rich plasma injection is more effective than intraarticular hyaluronic acid injection in the treatment of knee osteoarthritis: a systematic r... by Yu-Ning Peng, Yu-Hsiang Peng, Jean-Lon Chen, Carl P. C. Chen

“…Abstract Purpose We aim to compare the clinical effects of intraarticular leukocyte-poor platelet-rich plasma (LP-PRP) injection with those of intraarticular hyaluronic acid (HA) injection in adult patients with knee osteoarthritis. Methods Two authors independently reviewed databases, including PubMed, Web of Science, and the Cochrane Library. …”
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En bloc resection of the ligamentum flavum for bilateral decompression in unilateral biportal endoscopic transforaminal lumbar interbody fusion: a 2-year follow-up study by Chao Li, Beiyu Xu, Yao Zhao, Longtao Qi, Lei Yue, Ranlyu Zhu, Chunde Li, Zhengrong Yu

“…This study has refined UBE-TLIF to incorporate en bloc resection of the ligamentum flavum for bilateral decompression and aim to detail the surgical procedure and evaluate the clinical outcomes of this modification. Methods This study analyzes the outcomes of 109 consecutive patients treated by a single surgeon for lumbar degenerative disease using UBE-TLIF. …”
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Sex differences in the efficacy of antihypertensive treatment in preventing cardiovascular outcomes and reducing blood pressure: protocol for a systematic review and meta-analysis by Karina Gasbarrino, Christopher Labos, Victoria Mastropietro, Lindsay Hales, Doreen Rabi, Stella S Daskalopoulou

“…Publication bias will be assessed by visual inspection of funnel plots and by Begg’s and Egger’s statistical tests. …”
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Desflurane general anesthesia for deep brain stimulation in Parkinson′s disease patients by TONG Yuanyuan, XIONG Wei, LI Xiangjiahui, CHEN Liang, FAN Yifang, HAN Ruquan, XIE Sining

“…Objective Feasibility application of microelectrode recording (MER) during sub thalamic nucleus deep brain stimulation (STN-DBS) implantation under desflurane general anesthesia(GA) in patients with Parkinson′s disease (PD). Methods A prospective cohort of 20 PD patients undergoing STN-DBS under desflurane general anesthesia were enrolled. …”
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Cerebral palsy in preterm infants by Demeši-Drljan Čila, Mikov Aleksandra, Filipović Karmela, Tomašević-Todorović Snežana, Knežević Aleksandar, Krasnik Rastislava

“…Methods. The sample size was 206 children with CP. …”
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Evaluating Dexmedetomidine and Ketamine for Control of Post-Operative Pain in Lower Segment Caesarean Section Surgeries by Ahmed Naeem, Amna Batool, Syed Muhammad Ali, Muhammad Ahmad Saroosh Saleem, Ayesha Shafqat, Khalid Javid Siddiqi

“…To compare the analgesic efficacy and safety of three different doses of dexmedetomidine combined with a fixed dose of ketamine for postoperative pain control after LSCS. Methods: In this randomized controlled trial RCT Registered (NCT07022821), 90 participants undergoing elective LSCS under spinal anesthesia were assigned to one of three groups (n=30 each) from March to May 2025 at Department of Anesthesia FMH Lahore. …”
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Influence of Aging and Diabetes on the Mechanical Properties of Mouse Skin by Sarah Miny, Gaël Runel, Julien Chlasta, Christelle Bonod

“…We therefore investigated whether it was possible to detect differences in the biomechanical properties of the reticular dermis by comparing C57/BL6 control mice, type 1 and type 2 diabetic mice, and aged mice. Methods: To investigate this, we used an Atomic Force Microscope (a type of local probe microscope used to visualize the surface topography of a sample) to measure the elastic modulus of each skin sample. …”
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Comparison between Transepithelial Photorefractive Keratectomy versus Alcohol-Assisted Photorefractive Keratectomy in Correction of Myopia and Myopic Astigmatism by Ashraf M. Bakhsh, Shaaban A. M. Elwan, Ahsan A. Chaudhry, Tamer M. El-Atris, Taghleb M. Al-Howish

“…Prospective, nonrandomized case-control comparative study. Methods. A total of 200 eyes of 100 consecutive patients were included. …”
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ANALYSIS OF SURFACE DEFECTS OF ALUMINUM AND ITS ALLOYS WITH A SCANNING KELVIN PROBE by A. K. Tyavlovsky, A. L. Zharin, O. K. Gusev, R. I. Varabei, N. I. Muhurov, G. V. Sharonov, K. U. Pantsialeyeu

“…The study aims to the use of probe electrometry methods for nondestructive testing and analysis of precision metal surfaces’ defects after different treatment or processing.Control of surface defects of aluminum and its alloys was performed with a scanning Kelvin probe technique. …”
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Effect of a Modern Palaeolithic Diet in Combination with a Sprint Interval Training on Metabolic and Performance-Related Parameters in Male Athletes: A Pilot Trial by Denise Zdzieblik, Tobias Waldvogel, Anna Zierke, Albert Gollhofer, Daniel König

“…Objective: This study examined the impact of a 6-week palaeolithic diet (PD-G) versus a mixed diet (MD-G), both paired with Sprint interval training (SIT), on various metabolic and performance-related parameters. Methods: Body composition, time trial (TT) performance (covered distance during a 60-minute run on a 400-metre track) and changes in metabolic (respiratory exchange ratio [RER], substrate oxidation rates) and performance-related (time at ventilatory threshold [VT] and respiratory compensation point [RCP], maximum oxygen uptake (V̇O 2max ) and time to exhaustion [TTE]) parameters during a ramp incremental running test were assessed in 14 male endurance athletes. …”
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ESTIMATION OF DIACEREIN TOLERABILITY IN REAL CLINICAL PRACTICE: RESULTS OF THE RACADA (RETROSPECTIVE ASSESSMENT OF CLINICAL ASPECTS OF USING DIAFLEX IN OSTEOARTHRITIS) by A. E. Karateev, L. I. Alekseeva

“…However,Russiahas not conducted  its own large-scale trials of the safety of DR despite its popularity.Objective: to estimate the frequency of AE of DR (Diaflex®, Romfarm) in real clinical practice.Subjects and methods. The use of DR was retrospectively analyzed in 3479 patients (60.4% women and 39.6% men; mean age 57.6±12.6 years) with OA and back pain. …”
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Cognitive Decline in Patients With Trigeminal Neuralgia: A Resting‐State fMRI Study by Xueyun Deng, Lihua Liu, Jiafei Chen, Zhi Liu, Hua Feng

“…ABSTRACT Objective This study utilized functional magnetic resonance imaging (fMRI) data to investigate cognitive function changes in trigeminal neuralgia (TN) patients and healthy controls (HCs), and to elucidate the potential mechanism. Materials and Methods The cognitive function of 34 patients with TN and 30 HCs was evaluated. …”
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