Gram-negative bacteria activate cellular pathways in plaque microenvironment; Systems biology approach by Reza Ganjali, Mohammad Elahimanesh, Hamidreza Aghazadeh, Mohammad Najafi

“…Moreover, it aimed at cross-talking and enriching the pathways on the cellular and plaque networks. Methods and Materials High-throughput expression data series (n = 9) were selected through GEO and MAT data repositories. …”
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In-depth meta-analysis: unilateral PKP demonstrates significant advantages in treating osteoporotic vertebral compression fractures—an expanded RCT study with GRADE scoring by Lin Xiao, Wei Li, Jingxin Yan, Lei Luo, Ting Li

“…While existing systematic reviews comparing unilateral and bilateral PKP approaches provide preliminary insights, they are limited by methodological inconsistencies and inconclusive evidence regarding comparative efficacy.MethodsWe conducted a comprehensive systematic review of randomized controlled trials (RCTs) up to July 2024, searching major English databases (Cochrane Library, Embase, PubMed, Scopus, Web of Science) and Chinese databases (CNKI, VIP, and Wanfang).ResultsThe pooled analysis of 35 RCTs (N = 3,362) revealed no statistically significant differences between unilateral and bilateral PKP in long-term outcomes, including visual analog scale scores (P = 0.62), Oswestry Disability Index scores (P = 0.77), and Cobb angle correction (P = 0.64). …”
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Bias in carnivore diet analysis resulting from misclassification of predator scats based on field identification by Dana J. Morin, Summer D. Higdon, Jennifer L. Holub, David M. Montague, Michael L. Fies, Lisette P. Waits, Marcella J. Kelly

“…Advancements in noninvasive genetic sampling allow for molecular identification of predator scat, eliminating many issues associated with field identification methods. We collected scat samples once per month from June 2011 to May 2012 in western Virginia, USA, using morphological characteristics for field identification of the predator. …”
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Outcomes of Ureteral Stent Removal by Flexible Cystoscope Versus Semirigid Ureteroscope: A Prospective Randomized Clinical Trial by Ketan Mehra, Neeraj Agarwal, Ramanitharan Manikandan

“…In this study we compared semirigid ureteroscope with a flexible cystoscope for retrieving stents.Materials and Methods:It was a prospective randomized clinical trial including 100 patients. …”
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Is partial excision of the radial head safe and effective in all-arthroscopic treatment of terrible triad fractures? by Hyung Gyu Cho, Gyeong Hoon Lim, Min Su Joo, Jae Won Kim, Jun Ho Park, Jeong Woo Kim

“…Background Our study aimed to evaluate the clinical and radiologic results of all-arthroscopic treatment of terrible triad injuries followed-up for a minimum of 5 years and investigate how arthroscopic partial excision for radial head fractures affects the results at the final follow-up. Methods We retrospectively reviewed consecutive patients with terrible triad injuries who underwent all-arthroscopic treatment between January 2011 and June 2018. …”
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Correlation between the number of intravitreal injections and acquired blepharoptosis caused by eyelid speculum: a prospective study by Batuhan Aksoy, Senihe R. Yildirim

“…Objectives To investigate the correlation between the number of intravitreal injection applications and possible involutional blepharoptosis secondary to the eyelid speculum used during this procedure with real-life data. Patients and methods This prospective study consisted of 34 eyes of 30 patients. …”
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159 Benefits of career development grant coaching groups for early career clinical and translational investigators beyond funding success by Sudeshna De, Kharma Foucher

“…We evaluated the impact of early career grant coaching on applicants’ perceived preparedness for grant submission, confidence in securing grants, and self-reported benefits. Methods/Study Population: Modeled after the National Research Mentoring Network, groups of ~5 investigators who wanted to submit a career development grant proposal met weekly for ~12 weeks with a senior faculty coach to refine aims pages, biosketches, and career development plans using a real-time peer review process. …”
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Intermediate and Long-Term Outcomes of Glaucoma Drainage Device Implantation by Glaucoma Fellows at a Tertiary Eye Center by Cris Martin P. Jacoba, MD, John Mark S. de Leon, MD, DPBO

“…Objective: To describe surgical outcomes of glaucoma drainage device (GDD) implantation performed by glaucoma fellows, and to identify factors influencing success. Methods: This is a retrospective case series of eyes with GDDs implanted by glaucoma fellows at a tertiary eye center in the Philippines from February 2015 to March 2017. …”
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Phacovitrectomy vs. consecutive vitrectomy for idiopathic macular holes: short and long-term outcomes and OCT image quality assessment by Vishma Prabhu, Priyanka Gandhi, Rupal Kathare, Kanika Godani, Prathiba Hande, Naresh Kumar Yadav, Jay Chhablani, Ramesh Venkatesh

“…Also, to evaluate the role of preoperative optical coherence tomography (OCT) image quality in guiding surgical selection. Methods This retrospective study analyzed 183 phakic MH eyes operated between 2012 and 23, with patients divided into PVS and CVS groups. …”
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Bedside ultrasound-guided genicular nerve block with corticosteroids and lignocaine for knee osteoarthritis improves pain and participation, and is safe in inpatient rehabilitation... by Edmund J. R. Neo, Trier T. N. Lau, Khin Yamin Thein, San San Tay

“…This is the first effort to document its application in the inpatient rehabilitation setting.MethodsThis was a retrospective case series. We reviewed the medical records of inpatients undergoing rehabilitation who underwent the US GNB for disabling knee OA between July 1, 2022, and August 31, 2023. …”
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The use of symptomatic slow-acting drugs for osteoarthritis of the joints of the hands: Accent on microcirculation parameters by A. S. Trofimova, V. I. Mazurov, A. A. Shokhin, E. A. Trofimov

“…The aim of the study – to evaluate the effectiveness of the drug Alflutop (bioactive concentrate of small marine fish), as well as its effect on microcirculation parameters in patients with osteoarthritis (OA) of small joints of the hands.Patients and methods. The study included 80 patients aged 35 to 65 years with OA of small joints of the hands, stage I– II according to Kellgren – Lawrence, with pain ≥40 mm and ≤90 mm on a visual analogue scale (VAS). …”
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A Machine Learning–Based Prediction Model for Acute Kidney Injury in Patients With Community-Acquired Pneumonia: Multicenter Validation Study by Mengqing Ma, Caimei Chen, Dawei Chen, Hao Zhang, Xia Du, Qing Sun, Li Fan, Huiping Kong, Xueting Chen, Changchun Cao, Xin Wan

“…ObjectiveThis study aimed to establish and validate predictive models for AKI in hospitalized patients with CAP based on machine learning algorithms. MethodsWe trained and externally validated 5 machine learning algorithms, including logistic regression, support vector machine, random forest, extreme gradient boosting, and deep forest (DF). …”
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Toward Real-Time Recognition of Continuous Indian Sign Language: A Multi-Modal Approach Using RGB and Pose by M. Geetha, Neena Aloysius, Darshik A. Somasundaran, Amritha Raghunath, Prema Nedungadi

“…Sign language recognition (SLR) involves translating visual gestures into meaningful text or speech, bridging the communication gap between signers and non-signers. …”
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Baseline characteristics associated with the first year treatment interval of intravitreal faricimab in neovascular age-related macular degeneration (nAMD) by Sobha Sivaprasad, Philippe Margaron, Aachal Kotecha, Thibaud Mathis, Parth Shah, Neala Rafijah, Yannan Tang

“…Aims To identify baseline characteristics that best correlate to treatment interval for naive neovascular age-related macular degeneration patients treated with faricimab in the first year (Y1) of the TENAYA and LUCERNE phase 3 trials, and to further understand how these characteristics may impact treatment intervals.Methods This post-hoc analysis of Y1 data from the TENAYA and LUCERNE trials evaluated ocular baseline characteristics associated with Y1 treatment intervals. …”
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Prognostic Factors of Percutaneous Vertebroplasty for Vertebral Compression Fracture and Risk Factors of New Symptomatic Compression Fracture by Wen-Chien Wang, Cheng-Hung Lee, Kun-Hui Chen, Chien-Chou Pan, Cheng-Min Shih, Wen-Hsien Lu, Wei-En Hsu

“…Objectives: This study aimed to identify the prognostic factors for the outcomes of PVP in patients with VCFs and evaluate the risk factors associated with new symptomatic compression fractures. Materials and Methods: We conducted a retrospective analysis of patients who underwent single level PVP performed by five surgeons for symptomatic VCFs between June 2013 and January 2015. …”
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Resilience Enhancement Strategies for Energy Systems in the Face of Natural Calamities and Cyber Threats: A Comprehensive Review by Mostafa Shabanian-Poodeh, Rahmat-Allah Hooshmand, Miadreza Shafie-Khah, Pierluigi Siano

“…Since uncertainties play a crucial role in decision-making within this field, this paper broadly explores methods for addressing them as presented in previous studies. …”
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Impact of Chronic Smoking on Choroidal Thickness: A Comparative Analysis Using Optical Coherence Tomography by Ranabir Mazumdar, Subhamitra Maulik, Nazir Abdul Wasim

“…Methods: This was a case-control study conducted at the Regional Institute of Ophthalmology, Medical College, Kolkata, India between January 2023 and June 2024. …”
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Degenerate cases in discrete Lotka – Volterra dynamical systems by Ganikhodzhaev, Rasul Nabiyevich, Eshmamatova, Dilfuza Bakhromovna, Муминов, Улугбек Рахимжонович, Masharipov, Sirojiddin Ismoyiljon ugli

“…At the same time, the limiting sets of positive and negative orbits are of particular interest. Methods. It is known that for Lotka–Volterra mappings it is possible to define limit sets, which in the case of non-degenerate mappings consist of a single point. …”
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Quantifying Suicide Risk in Prostate Cancer: A SEER-Based Predictive Model by Jiaxing Du, Fen Zhang, Weinan Zheng, Xue Lu, Huiyi Yu, Jian Zeng, Sujun Chen

“…This study aimed to develop a nomogram for identifying high-risk patients and providing empirical evidence to guide effective intervention strategies. Methods We analyzed data from 176,730 prostate cancer patients diagnosed between 2004 and 2021, sourced from the Surveillance, Epidemiology, and End Results (SEER) database. …”
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Immediate effects of exercise snacking on physical fatigue, mood, and pain in elderly adults with knee osteoarthritis by Ayoola Ibifubara Aiyegbusi, Francis Oluwatosin Kolawole, Israel Kayode Oke, Henrietta O. Fawole

“…The aim of this study was to investigate the immediate impact of exercise snacking versus continuous exercise on physical fatigue, mood, and pain level in elderly adults with KOA. Methods This was a randomized experimental study, with 37 participants aged 60 years and above with KOA. …”
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