Ultrasound and single‐port laparoscopic‐guided microwave ablation of abdominal wall endometriosis lesions: A single‐center observational study by Shunshi Yang, Jueying Li, Jingjing Li, Xiaoyu Zhao, Mengying Li, Yi Zhang, Xiong Li, Ying Chen

“…The adverse events and complications were Common Terminology Criteria for Adverse Events grade 1 or Society of Interventional Radiology classification grade A. Material and Methods This historical study included 30 patients with abdominal wall endometriosis who underwent ultrasound and single‐port laparoscopic‐guided microwave ablation at the Ultrasonography and Gynecology Department of the Wuhan Central Hospital between October 2017 and February 2022. …”
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Features of pathological changes of fibro-cartilaginous tissue knee in patients with Baker cyst by S. A. Chernyad'ev, A. I. Chernookov, E. A. Grebenev, N. I. Sivkova, A. V. Zhilyakov, D. A. Babushkin, N. Yu. Korobova, O. A. Vinogradov

“…Objective: using magnetic resonance imaging (MRI) to evaluate the characteristics of pathological changes of fibro-cartilage of the knee in patients with Baker cyst, to assess the compliance of degrees of damage stages of osteoarthritis on a scale of Kellgren–Lawrence (K–L), and compare the results with the data of other researchers.Material and methods. This study included patients (38–82 years) with a cyst Baker accidentally detected during ultrasound veins of the lower extremities. …”
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Predictive factors for response to viscosupplementation in patients with knee osteoarthritis: an analysis of clinical and imaging factors by Gustavo Rossanese Pinto, Guilherme Conforto Gracitelli, Fernando Cury Rezende, Claudio Gattas, Thais Cristina Pereira Vasques, Flavio Duarte Silva, Carlos Eduardo da Silveira Franciozi, Marcus Vinicius Malheiros Luzo

“…Results: The results showed a significant reduction in WOMAC and Visual Analog Scale scores for all evaluated times after VS compared to baseline. …”
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Virtual Reality and Sound Intervention under Chemotherapy (ViSu): study protocol for a three-arm randomised-controlled trial by Andre Karger, Luisa Ernsten, Steffen Holsteg, Nora K Schaal, Luisa M Keßling, Nele Schmutzler, Tanja N Fehm, Verena Friebe, Norbert Gattermann, Eugen Ruckhäberle

“…Virtual reality (VR) offers the potential to visually and audibly disengage from the surrounding environment and can create an alternative sense of presence. …”
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Acanthamoeba keratitis in a tertiary referral hospital in central China: demographics, risk factors, clinical presentation, treatments and outcomes by Jia-Song Wang, Dan Zhao, Tian-Yu Yao, Xiao-Ying Jiang, Hua-Tao Xie, Ming-Chang Zhang

“…AIM: To investigate the demographics, risk factors, clinical presentation, treatments and outcomes of Acanthamoeba keratitis (AK) in a tertiary referral hospital in central China. METHODS: In this noncomparative, retrospective study, a total of 21 AK patients were enrolled between April 2020 and March 2023. …”
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Exploring Molecular Pathways in Refractive Errors Associated with Inherited Retinal Dystrophies by Fabiana D’Esposito, Caterina Gagliano, Alessandro Avitabile, Giuseppe Gagliano, Mutali Musa, Matteo Capobianco, Federico Visalli, Edoardo Dammino, Marco Zeppieri, Maria Francesca Cordeiro

“…We also discuss the therapeutic implications of refractive defects in individuals with IRD, including possible approaches to treating visual impairments. In addition, we address the value of using cutting-edge imaging methods and animal models to examine refractive errors linked to IRDs and suggest future lines of inquiry for identifying new targets for treatment. …”
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Honey, Gellan Gum, and Hyaluronic Acid as Therapeutic Approaches for Skin Regeneration by Patrícia Sousa, Alicia Moreira, Bruna Lopes, Ana Catarina Sousa, André Coelho, Alexandra Rêma, Maria Balça, Luís Atayde, Carla Mendonça, Lucília P. da Silva, Cristiana Costa, Alexandra P. Marques, Irina Amorim, Rui Alvites, Filipa Batista, Filipa Mata, João Transmontano, Ana Colette Maurício

“…The formulations were designed to balance therapeutic efficacy with cost-effectiveness, leveraging low-cost raw materials and straightforward production methods.…”
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LianChuang ZhiXue Liquid Enema Modulates the Macrophage Polarization of Ulcerative Colitis via Inhibiting the Jagged-1/Notch1 Signaling Pathway by Zhang Y, Liu J, Zhang D, Qian H

“…However, its specific molecular mechanism has not been clarified to explore the underlying macular mechanism of LCZXL enema effect on UC, based on Jagged-1/Notch1 signaling pathway and the macrophage polarization.Methods: After modeling of UC mice, the experiment was conducted in two parts: Experiment I: Control, Model, Mesalazine, Low dose of LCZXL (LCZXL-L), High dose of LCZXL (LCZXL-H); Weight and Disease Activity Index (DAI) scores were recorded on days 1, 3, 5, 7, 9, 11, and 13. …”
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Identification of Ferroptosis -Related Genes in MAFLD/MASH and HQHF Validation by Liu S, Zhang L, Xu J, Zhao Q, Shang D, Liu X, Zhang Q, Liu M, Zhao W

“…This study aims to identify differentially expressed genes (DEGs) associated with MAFLD/MASH and explore their potential link to ferroptosis, a form of regulated cell death.Methods: We conducted differential expression analysis using two datasets from the GEO database. …”
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The Adjunctive Effect of Quercetin on Postoperative Pain Management Following Cesarean Section: A Randomized Controlled Study by Mohamed Elmokadem E, Khaled Abou El Fadl D, Bassiouny AM, Mahmoud MMAE, Samy M, El Said NO

“…The primary outcome was postoperative pain intensity assessed using a 10 cm Visual Analog Scale (VAS) at 2, 6, 12, and 24 hours after surgery. …”
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The Different Immune Response Between Onset and Remission of AQP4 Antibody-Positive Optic Neuritis Based on RNA Sequencing of Whole Blood by Shi R, Luo Y, Chen Y, Chen X, Li S, Chen Z, Wang K, Zou W

“…Ruohan Shi,1,* Yidan Luo,2,3,* Yusheng Chen,1,2,* Xuelian Chen,4 Shiyi Li,5 Ziqing Chen,1 Ke Wang,6,7 Wenjun Zou1,2 1Department of Ophthalmology, Wuxi No.2 People’s Hospital, Jiangnan University Medical Center(JUMC), Wuxi, Jiangsu, People’s Republic of China; 2Department of Ophthalmology, Affiliated Wuxi Clinical College of Nantong University, Wuxi, Jiangsu, People’s Republic of China; 3Department of Comprehensive Ophthalmology, Wuhan Bright Eye Hospital, Wuhan, Hubei, People’s Republic of China; 4Department of Ophthalmology, PuNan Branch of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 5Department of Ophthalmology, Jingjiang People’s Hospital Affiliated to Yangzhou University, Taizhou, Jiangsu, People’s Republic of China; 6National Health Commission (NHC) Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, People’s Republic of China; 7Department of Radiopharmaceuticals, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wenjun Zou, Department of Ophthalmology, Wuxi No.2 People’s Hospital, Jiangnan University Medical Center (JUMC), Wuxi, Jiangsu, People’s Republic of China, Tel +86-510-6856-3091, Fax +8668562052, Email wenjunzou2022@163.comPurpose: We aimed to investigate differences in the immune response between the onset and remission phases of AQP4 antibody-positive optic neuritis (AQP4-ON).Methods: Whole blood samples were collected from 7 healthy volunteers, 6 patients with AQP4-ON in the acute phase and 6 patients with AQP4-ON in the remission phase. …”
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Clinical Efficacy of Acupuncture in the Treatment of Uterine Contraction Pain Post-Cesarean Section: Protocol of a Randomized Controlled Trial by Deng Y, Li Z, Zhang T, Tang X, Luo Y, Li Q, Zhang S, Liu Z, Tang D, Ai Z, Guo T, Liang F

“…This study uses acupuncture as an intervention and aimed to provide strong evidence for the clinical efficacy of acupuncture in treating UCPCS.Patients and Methods: This single-blind, randomized controlled trial (RCT) was conducted at the Ludian County Hospital of Traditional Chinese Medicine, China. …”
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The results of investigating the efficacy and safety of non-medical switching from the original rituximab to its biosimilar in rheumatoid arthritis patients (AMBIRA study) by M. A. Korolev, Yu. B. Ubshaeva, N. Y. Banshchikova, E. A. Letyagina, A. A. Mullagaliev

“….”, Switzerland) to its biosimilar (Acellbia®, “BIOCAD”, Russia) by non-medical reasons in rheumatoid arthritis patients.Subjects and methods. 40 rheumatoid arthritis patients on basic therapy who had taken at least one course of original rituximab (MabThera®) 1000 mg twice in 2 weeks more than 6 months ago were included. …”
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Integrating Deep Learning and Radiomics in Differentiating Papillary Thyroid Microcarcinoma from Papillary Thyroid Carcinoma with Ultrasound Images by Yu B, He H, Zheng Q, Ai Y, Yu X, Li S, Zhang J, Jin J, Jin X, Yu W

“…Bing Yu,1,2,* Huijuan He,3,* Qiao Zheng,2,* Yao Ai,2 Xianwen Yu,2 Sunjun Li,4 Ji Zhang,2 Juebin Jin,5 Xiance Jin,2,6 Wenliang Yu3 1Purchasing Center Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310020, People’s Republic of China; 2Radiation and Medical Oncology Department, Wenzhou Medical University First Affiliated Hospital, Wenzhou, 325000, People’s Republic of China; 3Radiation Oncology Department, Quzhou People’s Hospital, Quzhou, 324002, People’s Republic of China; 4Alberta College, Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China; 5Medical Engineering Department, Wenzhou Medical University First Affiliated Hospital, Wenzhou, 325000, People’s Republic of China; 6School of Basic Medical Science, Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiance Jin, Radiation and Medical Oncology Department, Wenzhou Medical University First Affiliated Hospital, Wenzhou, 325000, People’s Republic of China, Email jinxc1979@hotmail.com Wenliang Yu, Radiation Oncology Department, Quzhou People’s Hospital, Quzhou, 324002, People’s Republic of China, Email wlyu1982@aliyun.comPurpose: The feasibility and accuracy of ultrasound-based radiomics, deep learning, and combined deep learning radiomics models were investigated in the differentiation of papillary thyroid carcinoma and papillary thyroid microcarcinoma to decrease the risk of overtreatment of papillary thyroid microcarcinoma.Methods: A total of 549 patients with confirmed 180 papillary thyroid carcinoma and 436 papillary thyroid microcarcinoma nodules from Hospital One were enrolled and randomly divided into training and validation cohorts at a ratio of 8:2 with 56 patients left as independent testing set 1. …”
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Predicting Short-Term Risk of Cardiovascular Events in the Elderly Population: A Retrospective Study in Shanghai, China by Zhu W, Tan S, Zhou Z, Zhao M, Wang Y, Li Q, Zheng Y, Shi J

“…This study aimed to develop a short-term risk prediction model for CVD events among individuals aged ≥ 60 years in Shanghai, China.Methods: Stratified random sampling recruited elderly individuals. …”
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Pre-clinical safety studies of intranasal virus-like particles based vaccine for prevention of COVID-19 by Yana Y. Chernoryzh, Valeria M. Kondratieva, Аnastasia P. Malkova, Tatyana E. Savochkina, Olesya V. Eliseeva, Oleg E. Latyshev, Dmitriy Y. Yakunin, Olga N. Zaykova, Ekaterina S. Sludnyakova, Tatyana V. Grebennikova

“…The aim of the study is to conduct preclinical acute and subchronic toxicity studies assessing local tolerability of an intranasal VLP vaccine against COVID-19 in accordance with good laboratory practice. Materials and methods. Study was performed on adult outbreed mice (30 males, 30 females) and rats (45 males, 45 females). …”
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Inhibition of Rho Kinase Induces Antioxidative Molecules and Suppresses Reactive Oxidative Species in Trabecular Meshwork Cells by Tomokazu Fujimoto, Toshihiro Inoue, Saori Ohira, Nanako Awai-Kasaoka, Takanori Kameda, Miyuki Inoue-Mochita, Hidenobu Tanihara

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Meibomian Gland Dysfunction in Type 2 Diabetic Patients by Xiaolei Lin, Binbin Xu, Yuxi Zheng, Terry G. Coursey, Yinying Zhao, Junhua Li, Yana Fu, Xuewen Chen, Yun-e Zhao

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Optical coherence tomography angiography study on retinochoroidal thickness and blood flow changes after posterior scleral reinforcement surgery by Yongqi Mao, Hao Chen, Yunhua Tang, Haoming Geng, Fuwen Zhang

“…Purpose: Based on optical coherence tomography angiography (OCTA), we investigate the effects of posterior scleral reinforcement surgery on the fundus structure and function in patients with high myopia. Methods: Retrospective clinical study. Forty cases (41eyes) of high myopia patients who underwent posterior scleral reinforcement surgery at Chengdu University of Traditional Chinese Medicine Affiliated Silver Eye Hospital from January 2022 to January 2025 were selected. …”
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Association of different kinds of obesity with diabetic retinopathy in patients with type 2 diabetes by Xiaoling Liang, Wei Wang, Ling Jin, Wenyong Huang, Wangting Li, Lanhua Wang, Xia Gong, Jie Meng, Yuting Li, Kun Xiong

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