Assessment of Brazilian children’s anxiety during the second year of the COVID-19 pandemic through cross-sectional interviews at schools by Patrícia Aparecida Francelino Crepalde, Marla Andréia Garcia de Avila, Michelle Cristine de Oliveira Minharro, Meire Cristina Novelli Castro, Tatiane Roberta Fernandes Teixeira, Pedro Tadao Hamamoto Filho, Stefan Nilsson, Stefan Nilsson, Stefan Nilsson

“…IntroductionThis cross-sectional study aimed to assess anxiety prevalence among schoolchildren and associated factors following their return to in-person classes during the COVID-19 pandemic.MethodsThis study was conducted in June 2022 and involved children aged 6–12 years and their parents at four public schools in Brazil. …”
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Clinical observation on the therapeutic effect of open intersphincteric groove incision in the LIFT procedure for transsphincteric anal fistula by Zhang Yang, Zhao Tuanjie, Dong Wanqing, Su Yue, Zhang Zhiliang, Liu Zixi

“…[Objectives] To observe the clinical effect of open intersphincteric groove incision in the ligation of the intersphincteric fistula tract (LIFT) procedure for transsphincteric anal fistula. [Methods] A total of 97 patients with transsphincteric anal fistula were randomly divided into an observation group (treated with modified LIFT with open intersphincteric groove incision, n=49) and a control group (treated with conventional LIFT with closed intersphincteric groove incision, n=48). …”
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Effects of Night-Time Use of Rotigotine on Nocturnal Symptoms in Parkinson’s Disease by Francesc Vallderiola, Yaroslau Compta, Javier Aparicio, Jaume Tarradellas, Gabriel Salazar, Josep María Oliver, Antonio Callén, Tania Delgado, Fritz Nobbe

“…This open-label study assessed the efficacy and safety of exclusive night-time administration of transdermal rotigotine in patients with nocturnal and early morning PD symptoms. Methods. Patients with PD and nocturnal and early morning symptoms received transdermal rotigotine patches (2–16 mg/24 h) applied in the evening and removed in the morning for 3 months. …”
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Unveiling GFAP Astrocytopathy: Insights from Case Studies and a Comprehensive Review of the Literature by Panagiotis Gklinos, Fotios Athanasopoulos, Vagia Giatrakou, Nikolaos-Achilleas Arkoudis, Dorothea Pournara, Eirini Giagkou, Argyro Tountopoulou, Sofia Vassilopoulou, Dimos-Dimitrios Mitsikostas

“…Other symptoms include headache, visual disturbances, extrapyramidal or brainstem syndromes, and psychiatric manifestations including psychosis. …”
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Explainable AI-Based Skin Cancer Detection Using CNN, Particle Swarm Optimization and Machine Learning by Syed Adil Hussain Shah, Syed Taimoor Hussain Shah, Roa’a Khaled, Andrea Buccoliero, Syed Baqir Hussain Shah, Angelo Di Terlizzi, Giacomo Di Benedetto, Marco Agostino Deriu

“…Traditional diagnostic methods, based on visual examination, are subjective, time-intensive, and require specialized expertise. …”
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Reshaping research in crisis: bibliometric analysis of Ecuadorian public universities during COVID-19 (2019–2021) by Bill Serrano-Orellana, Jorge Guido Sotomayor-Pereira, Oscar Geovanny Riofrio Orozco, Luis Brito-Gaona, Patricio Alvarez-Muñoz, Patricio Alvarez-Muñoz, Marco Faytong-Haro

“…IntroductionEcuadorian public universities have significantly expanded their scientific output in recent years; however, few studies have conducted a multivariate bibliometric analysis to assess how these institutions adapted their research agendas during the COVID-19 pandemic.MethodsThis study examines publication patterns from 2019 to 2021 using data from the Web of Science, focusing on four primary research areas: Education, Social Sciences, Engineering, and Multidisciplinary Sciences. …”
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CLINICAL AND MORPHOLOGICAL ASPECTS OF THE APPLICATION OF PLATELET GROWTH FACTORS IN PATIENTS WITH PILONIDAL CYST WITH ABSCESS by E. E. Achkasov, A. Ya. Solomka, A. A. Ulyanov, Е. N. Bezuglov, E. V. Orekhova, T. M. Zharikova

“…The objective of this study is to investigate the surgical management of pilonidal cyst with abscess and to improve short-term and long-term outcomes.MATERIAL AND METHODS. The initial sample consisted of 353 patients operated for pilonidal cyst with abscess. …”
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Combined Phacoemulsification and Intravitreal Dexamethasone Implant (Ozurdex®) in Diabetic Patients with Coexisting Cataract and Diabetic Macular Edema by Claudio Furino, Francesco Boscia, Alfredo Niro, Ermete Giancipoli, Maria Oliva Grassi, Giuseppe D’amico Ricci, Francesco Blasetti, Michele Reibaldi, Giovanni Alessio

“…To investigate the effectiveness and safety of combined phacoemulsification and dexamethasone intravitreal implant in patients with cataract and diabetic macular edema. Methods. In this two-center, retrospective, single-group study, the charts of 16 consecutive patients who underwent combined phacoemulsification and intravitreal dexamethasone implant were retrospectively reviewed. …”
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Improved colorization and classification of intracranial tumor expanse in MRI images via hybrid scheme of Pix2Pix-cGANs and NASNet-large by Mavra Mehmood, Nasser Alshammari, Saad Awadh Alanazi, Asma Basharat, Fahad Ahmad, Muhammad Sajjad, Kashaf Junaid

“…The tumor can be curable if its stage and form can be identified on time, and for this purpose, researchers have been developing sophisticated techniques and methods. An automatic detection, segmentation, colorization, and classification of tumor region are done to identify abnormalities in a medical image using T1-CE, an MRI dataset that assists in diagnosis. …”
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Painful shoulder syndrome and upper limb function in competitive Painful shoulder syndrome and upper limb function in competitive swimmers by Beata POŻAROWSZCZYK-KUCZKO, Martyna KUMOREK, Dariusz MROCZEK, Filipe CLEMENTE, Wioletta DZIUBEK

“…The aim of this study was to evaluate whether PSS affects upper limb function in competitive swimmers. Material and methods. Thirty-two swimmers aged 17–24 years with at least 2nd sport class participated in the study. …”
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DeepVinci: Organ and Tool Segmentation with Edge Supervision and a Densely Multi-Scale Pyramid Module for Robot-Assisted Surgery by Li-An Tseng, Yuan-Chih Tsai, Meng-Yi Bai, Mei-Fang Li, Yi-Liang Lee, Kai-Jo Chiang, Yu-Chi Wang, Jing-Ming Guo

“…This study focuses on the first step in automated surgical navigation by identifying organs in gynecological surgery. <b>Methods</b>: Due to the difficulty of collecting da Vinci gynecological endoscopy data, we propose DeepVinci, a novel end-to-end high-performance encoder–decoder network based on convolutional neural networks (CNNs) for pixel-level organ semantic segmentation. …”
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Big Bubble Deep Anterior Lamellar Keratoplasty for Management of Deep Fungal Keratitis by Hua Gao, Peng Song, Jose J. Echegaray, Yanni Jia, Suxia Li, Man Du, Victor L. Perez, Weiyun Shi

“…To evaluate the therapeutic effect of big bubble deep anterior lamellar keratoplasty (DALK) in patients with deep fungal keratitis. Methods. Consecutive patients who had DALK for deep fungal keratitis at Shandong Eye Hospital between July 2011 and December 2012 were included. …”
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Gamelan Notation Reading Training for Elementary School Students at SDN Kedunglosari, Tembelang, Jombang by Wahyudi Wahyudi, Ayu Titis Rukmana Sari, Sutrisno Sahari, Bagus Amirul Mukmin, Wahid Ibnu Zaman, Abdul Aziz Hunaifi, Kukuh Andri Aka, Ronny Mahardika

“…The main objective was to provide basic understanding of the numerical symbols (1–7) in Javanese gamelan notation and to improve students' ability to read and perform gamelan notation collaboratively. The methods used included demonstrative and participatory approaches through hands-on practice, tone-based educational games, and visual media. …”
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A universal fluorescent lateral flow strip approach based on molecular beacon-assisted rolling circle amplification for point-of-care nucleic acid detection by Xiaopeng Chen, Wentao Wang, Pin Zhang, Qionglin Wang, Kangbo Liu, Fengfang Ding, Xianwei Zhang, Ligong Hou, Yingyu Zhang, Wancun Zhang

“…As a proof of concept, RCA-F-LFS can detect other nucleic acid targets by simply changing the target sequence, offering a robust and versatile strategy for the development of novel clinical POCT detection methods.…”
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Effectiveness and safety of a hydrophobic aspheric monofocal intraocular lens with molding process for cataract surgery by Liang-ping Liu, Ying-yan Qin, Qiang Lu, Qiang Wu, Guang-ying Zheng, Yi-yong Qian, Ying-zi Pan, Zhe-ming Wu, Jie-wei Liu, Hong-pei Ji, Xu-dong Huang, Ming-xing Wu

“…Abstract Background To evaluate the effectiveness and safety of a novel hydrophobic aspheric monofocal intraocular lens (IOL) in cataract surgery. Methods This is a prospective, multicenter, randomized, open-label, parallel-controlled clinical study, conducted at nine sites in P.R. …”
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Comparison of hair steroid levels among Wistar rats exposed to different environmental enrichment settings by Alberto Elmi, Niccolò I. Vannetti, Viola Galligioni, Nadia Govoni, Camilla Aniballi, José M. Sánchez-Morgado, Maria L. Bacci, Domenico Ventrella

“…This study aimed to compare the hair steroid profiles, specifically corticosterone, cortisol, and dehydroepiandrosterone (DHEA), of Wistar rats exposed to two different EE settings. Materials and Methods: Twenty (n = 20) outbred Wistar rats were enrolled in this study. …”
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Dysregulation of Retinal Melatonin Biosynthetic Pathway and Differential Expression of Retina-Specific Genes Following Blast-Induced Ocular Injury in Ferrets by Chetan Pundkar, Rex Jeya Rajkumar Samdavid Thanapaul, Manoj Govindarajulu, Gaurav Phuyal, Joseph B. Long, Peethambaran Arun

“…Similarly, retina-specific genes, such as <i>Rhodopsin</i>, <i>Melanopsin</i>, and RPE65, are essential for photoreceptor function, visual signaling, and the visual cycle. However, their responses to blast exposure have not been thoroughly investigated. …”
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Lycium barbarum polysaccharide inhibits retinal neovascularization and inflammation in vitro and in vivo by Bin Wu, Xue Wang, Wei Zhang, Xin Wang, Qi-Miao Wang, Ya-Ju Pang, Yi-Chun Kong

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Analysis of control arms in oncology randomised trials in Brazil: a cross-sectional study by Ana Elisa Boracini Sanches, Luiza Aleixo Barros Leite Fadul, Debora Aparecida Pires de Campos Zuccari, Beatriz de Menezes Dobbert, Lorena Forner, Júlia Belone Lopes, Daniel Vilarim Araujo

“…This trial aims to describe the control arms of randomised oncology trials recruiting in Brazil, an LMIC where the majority of patients receive care through the public health system, the Unified Health System (SUS), which provides limited access to cancer treatments.Methods and analysis This cross-sectional study included randomised clinical trials recruiting in Brazil on 4 December 2023 (ClinicalTrials.gov). …”
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Treatment Efficacy of Open Kinetic Chain Combined with Closed Kinetic Chain Exercise Training on Patients after Anterior Cruciate Ligament Reconstruction by GAO Peng, JIANG Xin, WANG Junzhe, WANG Hongyu, LIU Chengyao

“…ObjectiveTo observe the effect of open kinetic chain (OKC) combined with closed kinetic chain (CKC) exercise training on motor function of knee or lower limb, balance function, quadriceps isokinetic muscle strength and atrophy degree after anterior cruciate ligament (ACL) reconstruction.MethodsA total of 84 patients who underwent knee ACL reconstruction in the Jinan Zhangqiu District People's Hospital from January 2020 to October 2021 were randomly divided into OKC group, CKC group, equal combination group and adjusted combination group, with 21 cases in each group. …”
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