Mortality in the Volgograd Region Against the COVID-19 Pandemic by A. V. Alpatov

“…Estimation of excess mortality was carried out taking into account the dynamics of age-specific mortality rates.Materials and methods. The main sources of information for the study of mortality were the Russian database on fertility and mortality and Rosstat data. …”
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Pretreatment of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes with Quercetin Enhances the Healing of Diabetic Skin Wounds by Modulating Host-Microbiota Interactions by Wu S, Zhou Z, Li Y, Wu R, Jiang J

“…This study delves into the role of quercetin-pretreated MSC-derived exosomes (MSCsQr-exo) in accelerating the healing of diabetic wounds.Methods: MSCsQr-exo were isolated from quercetin-pretreated MSCs and applied to fibroblasts to evaluate changes in cell function. …”
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PREDICTION OF THE INFLUENCE OF ORIGINAL AND GENERIC ROSUVASTATIN ON DIRECT MEDICAL COSTS OF SECONDARY PREVENTION IN PATIENTS WITH CHRONIC TYPES OF ISCHEMIC HEART DISEASE by E. I. Tarlovskaya, G. I. Nechaeva, S. V. Malchikova, А. А. Semenkin

“…To study therapeutic equivalence of rosuvastatin generic and original medication and to conduct the pharmacoeconomic analysis to compare the impact of the drug on direct expenses in secondary prevention for the patients with chronic ischemic heart disease (CHD). Material and methods. The open label, prospective observational study performed with the switch of medication, that included 38 patients with chronic CHD and duration of 6 months. …”
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Analysis and Validation of a Diagnostic Nomogram for Predicting the Risk of Acute Respiratory Failure for Non-HIV Related Pneumocystis Jirovecii Pneumonia Patients by Bian W, Xin Y, Bao J, Gong P, Li R, Wang K, Xi W, Chen Y, Ni W, Gao Z

“…In this article, we explore the risk factors of ARF and propose a prognostic model of ARF for PCP patients.Methods: In this multi-center, retrospective study in 6 secondary or tertiary academic hospitals in China, 120 PCP patients were screened from the Dryad database for the development of a predictive model. …”
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Comparison of laparoscopic surgical skills acquired on a virtual reality simulator and a box trainer: an analysis for obstetrics-gynecology residents by M. Varras, C. Loukas, N. Nikiteas, V.K. Varra, F.N. Varra, E. Georgiou

“…The aim of this study was to compare the training efficacy of virtual reality (VR) simulators and box-trainers (BTs) for skills acquisition in gynecologic surgery, and also to study the transferability of these skills in the performance of more advanced gynecologic operations. Methods: Twenty residents in obstetrics-gynecology with minimal laparoscopic experience were randomized into two equal groups to be trained on either a VR simulator (Group-A) or a BT (Group-B). …”
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EPIDEMIOLOGY OF MALIGNANT TUMORS OF LARGE SALIVARY GLANDS (POPULATION-BASED STUDY) by V. M. Merabishvili, O. F. Chepik, E. N. Merabishvili

“…These values were 0000 equal to 0.7 and 0.4 0/ in Russia (2014), and 0.6 and 0.5 0/ in St. …”
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Serum afamin levels in women with polycystic ovary syndrome by Md. Jaminur Rashid, Md. Shahed-Morshed, Hurjahan Banu, Muhammad Abul Hasanat

“…This study aimed to assess the diagnostic performance of serum afamin in PCOS and the association of IR and metabolic syndrome (MS) in patients versus controls. Methods: This cross-sectional study included 40 women with PCOS based on the International Evidence-based Guideline, 2018, and an equal number of matched healthy controls from a university hospital between July 2020 and September 2021. …”
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Cost‐Effectiveness of Computer‐Assisted Cytology in a Primary hrHPV‐Based Cervical Cancer Screening Programme by Ellen M. G. Olthof, S. Kaljouw, Folkert J. vanKemenade, Anne M. Uyterlinde, Inge M. C. M. deKok

“…ABSTRACT Background Computer‐assisted screening (CAS) shows equal performance compared to manual screening, although results are heterogeneous. …”
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Treating overactive bladder symptoms after transurethral prostatic surgery for benign prostatic hyperplasia – Which medication to choose? by Cheng-Ling Lee, Hann-Chorng Kuo

“…This study compared the safety and efficacy between solifenacin and mirabegron in men undergoing TUR-P or TUI-P. Materials and Methods: This prospective, randomized trial compared the safety and efficacy of OAB medication on the reduction in Urgency Severity Score (USS), OAB Symptoms Score (OABSS), International Prostate Symptom Score, and urgency urinary incontinence episodes in men with BPO undergoing surgical intervention. …”
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Accuracy of physician self‐estimation of time spent during patient care in the emergency department by Martin A. Reznek, Virginia Mangolds, Kevin A. Kotkowski, Kian D. Samadian, James Joseph, Celine Larkin

“…Direct observation is time consuming and cost prohibitive, so we sought to determine if physician self‐estimation of time spent during patient care was accurate. Methods We performed a prospective, convenience‐sample study in which research assistants measured time spent by ED physicians in patient care. …”
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Comparative evaluation of push-out bond strength after root perforation repair using recently introduced bioceramic and calcium silicate-based materials – An in vitro study by Gurinder Kaur, Deepak Kurup, Deepyanti Dubey, Ajit Hindlekar, Ganesh Ranganath Jadhav, Priya Mittal, Siddharth Shinde

“…Aim: This study was planned to comparatively evaluate the push-out bond strength (PBS) after perforation (PF) repair using mineral trioxide aggregate (MTA) repair high plasticity (HP), Biodentine, and EndoSequence Bioceramic (BC) root repair material (ERRM). Methods: Ninety freshly extracted, intact, human molars were collected. …”
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Development and Characterization of 4A7: A High-Affinity Monoclonal Antibody Targeting Claudin18.2 by Wu Y, Tian J, Zhou Y, Zhang R, Gao X, Luo L

“…However, patients with advanced, unresectable, or metastatic GC or PC face poor prognoses, highlighting the urgent need for more effective Claudin18.2-targeted therapies.Methods and Results: We developed 4A7, a fully human monoclonal antibody with superior affinity and specificity for Claudin18.2, using a rigorous positive and negative screening strategy to eliminate cross-reactivity with Claudin18.1. …”
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Identification of Anoikis-Related Genes in Driving Immune-Inflammatory Responses in Ulcerative Colitis Based on Bioinformatics Analysis and Machine Learning by Diao W, Huang X, Huang W, Jiang J, Li W, Liu H, Yan B, Shen L

“…This study aims to explore the biological and clinical implications of anoikis-related genes (ARGs) in UC.Methods: Gene expression microarrays from normal and UC mucosal tissues focused on ARGs. …”
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Association of Tumor Necrosis Factor Alpha and Lymphotoxin Alpha Gene Polymorphisms with the Presence of Chronic Obstructive Pulmonary Disease by Amira P Tarigan, Tamsil Syafiuddin, Faisal Yunus, Suradi Suradi

“… Aim: to analyze the occurrence of chronic obstructive pulmonary disease (COPD) and its association with the polymorphisms of -308G/A, -238G/A of TNFα gene and +252A/G LTα gene polymorphism in smokers. Methods: cross-sectional study, comparing the genetic group of people who have COPD and who do not have COPD with the same smoking history. …”
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A Pharmaco-Economic Analyzis of Treating Severe Uncontrolled Child Asthma with Omalizumab — Actual Russian Clinical Practice Data by A. S. Kolbin, L. S. Namazova-Baranova, E. A. Vishneva, M. Y. Frolov, T. L. Galankin, A. A. Alekseeva, E. A. Dobrynina

“…The clinical-economic expediency of using omalizumab in asthmatic children has not been previously studied in Russia.Objective: Our aim was to evaluate the clinical and economic expediency of using omalizumab as additive treatment (to basic or supporting therapy) in children with severe uncontrolled atopic asthma under the Russian economic conditions.Methods: We conducted a mathematical simulation of asthma treatment in children with an increased frequency of hospitalization (9 times per year) with an average monthly omalizumab requirement of 558 mg. …”
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Making Hospitals More Dementia Friendly: An Inclusive, User-Centered Approach by Farsetta DL, Endicott SE, Woywod P, Bratzke LC

“…This contributes to poor outcomes for patients living with dementia, frustration and confusion for care partners, and distress for hospital staff.Patients and Methods: An academic project team with expertise in education, geriatrics, simulation, and community engagement, who had previously developed dementia-friendly training materials for classroom and community use, designed a dementia-friendly hospital toolkit. …”
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Data on Swiss consumers’ perception of different types of sustainability levies, agriculture and willingness to choose suboptimal potatoes in different settingsZenodo by Jeanine Ammann, Gabriele Mack, Rita Saleh

“…Specifically, participants’ trust in crop and livestock production farmers and their perceived knowledge about production methods and their affect towards farmers was assessed.In a second part, we collected quantitative data on participants’ preference for different sustainability levies. …”
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Effect of whey protein beverages on surface roughness of a packable resin composite by Michael Zacharia Mathew, Balaji Ganesh Subramanian, Somasundaram Jayalakshmi

“…Objective: This study aimed to analyze the effect of whey protein beverages on the surface roughness of a packable resin composite restorative material.Methods: Twenty disc-shaped specimens were prepared from a resin composite (Ivoclar Te-Econom Plus). …”
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The effect of vigorous continuous and interval exercise training along with resveratrol on SIRT3 and OGG1 proteins in the liver tissue of male Wistar rats by Mohammad Esmaeil Afzalpour, Hadi Sarir, Zoufa Zanjirian, Mohsen Moammadnia Ahmadi, ELHAM GHASEMI

“…The purpose of this study was to evaluate the effect of vigorous continuous and interval exercise training along with resveratrol on SIRT3 and OGG1 proteins in the liver tissue of male Wistar rats. Methods: In this research, forty-eight male Albino Wistar rats divided into six equal of eight groups including sedentary control, supplement, interval exercise, interval exercise + supplement, continuous training and continuous training+ supplement. …”
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Prevalence and Related Factors of Hypokalemia in Patients with Acute Ischemic Stroke by Luo Y, Hao J, Su Z, Huang Y, Ye F, Qiu Y, Liu Z, Chen Y, Sun R, Qiu Y

“…Yanfang Luo,1,* Jianru Hao,2,* Zhenzhen Su,1,* Yujuan Huang,1 Fen Ye,1 Yanhui Qiu,2 Zhimin Liu,2 Yuping Chen,3 Renjuan Sun,1 Yuyu Qiu2 1Department of Neurology, Affiliated Hospital of Jiangnan University, Wuxi, 214122, People’s Republic of China; 2Wuxi School of Medicine, Jiangnan University, Wuxi, 214126, People’s Republic of China; 3Department of Basic Medicine, Jiangsu Vocational College of Medicine, Yancheng, 224005, People’s Republic of China*These authors contributed equally to this workCorrespondence: Renjuan Sun; Yuyu Qiu, Email 15061885987@163.com; yuyuqiu@jiangnan.edu.cnAim: This study aimed to investigate the prevalence and associated factors of hypokalemia in patients with acute ischemic stroke.Methods: A cohort of 996 patients was assessed using a general data questionnaire, laboratory indicators, the NIH Stroke Scale (NIHSS), the Barthel Index (BI), the Frail scale, Nutritional Risk Screening (NRS-2002), and the Kubota drinking water test.Results: Among the 996 patients, 205 (20.6%) were found to have hypokalemia. …”
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