Evaluation of the RIFER procedure in treating high intersphincteric anal fistulas by Yan Ding, Yahong Xue, Yaqiu Miao, Huiting Zhu, Rui Ye, Xiaofeng Wang

“…This study aimed to evaluate the efficacy and safety of the rectal incision, fistula excision, and reconstruction (RIFER) procedure for treating high intersphincteric anal fistulas.MethodsTwenty-six patients with high intersphincteric anal fistulas who were admitted to Nanjing Hospital of Traditional Chinese Medicine between September 2021 and March 2024 and underwent the RIFER procedure were included. …”
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Investigating the Relationship Between Kinesiophobia, Catastrophizing, Pain Intensity, Disability, and Gait Performance in Chronic Neck Pain by Mersad Ery, Maryam Saadat, Saiedeh Monjezi, Masumeh Hessam, Mohammad Mehravar, Negar Amirabadi

“…This study evaluates gait performance in patients with neck pain and explores the relationship between gait performance and kinesiophobia, pain catastrophizing, pain intensity, and disability. Materials and Methods: A cross-sectional study was conducted on 34 patients with chronic neck pain and 29 age- and sex-matched controls were recruited for this study. …”
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Interaction between apolipoprotein E genotypes, excessive daytime sleepiness, and cognitive function in obstructive sleep apnea patients by Fernanda Maurer Balthazar, Walter André dos Santos Moraes, James Richard Hunter, Gilmar Fernandes do Prado, Luciane Bizari Coin de Carvalho

“…Objective To examine the cognitive function of adults with and without EDS and with and without ApoEε4. Methods A total of 21 male and female patients aged between 33 and 79 years, underwent a clinical interview, ApoE genotyping, neuropsychological evaluation, polysomnography, and the application of the Epworth Sleepiness Scale. …”
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Evaluation of Anxiety Levels in Patients Undergoing Intravitreal Injections and Associated Risk Factors Related to the Disease by Juan-Carlos Herranz-Heras, Almudena de-Pablo-Cabrera, Beatriz Alonso-Martín, Beatriz de-Lucas-Viejo, Marta de-Castro-Liébana, Enrique Mencía-Gutiérrez, Manuel-Jesús Ferro-Osuna, Carmen Romero, Javier Sambricio

“…Methods. Cross-sectional observational study with consecutive sampling of patients who were going to receive an intravitreal injection. …”
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The Clinical Features of Graves’ Orbitopathy with Elevated Intraocular Pressure by Shu-Xian Fan, Peng Zeng, Zi-Jing Li, Jing Wang, Jia-Qi Liang, Yun-Ru Liao, Yu-Xin Hu, Ming-Tong Xu, Mei Wang

“…To investigate the clinical characteristics of Graves’ orbitopathy (GO) with elevated intraocular pressure (IOP) using the European Group of Graves’ Orbitopathy (EUGOGO) system. Methods. In this retrospective study, the clinical data of GO patients with elevated IOP (≥21 mmHg) were collected in Sun Yat-sen Memorial Hospital from January 2010 to June 2016. …”
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stormTB: a web-based simulator of a murine minimal-PBPK model for anti-tuberculosis treatments by Roberto Visintainer, Anna Fochesato, Anna Fochesato, Daniele Boaretti, Stefano Giampiccolo, Stefano Giampiccolo, Shayne Watson, Micha Levi, Federico Reali, Luca Marchetti, Luca Marchetti

“…Drug-specific models are often tied to commercial software and developed on various platforms and languages, potentially hindering access and complicating the comparison of different compounds.MethodsThis work introduces stormTB: SimulaTOr of a muRine Minimal-pbpk model for anti-TB drugs. …”
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Comparison of the Clinical Outcomes between Echelette Extended Range of Vision and Diffractive Bifocal Intraocular Lenses by Xin Liu, Xiaohui Song, Wei Wang, Yanan Zhu, Danni Lyu, Xingchao Shentu, Peiqing Chen, Yibo Yu, Ke Yao

“…To compare the clinical outcomes of echelette extended range of vision (ERV) and diffractive bifocal intraocular lenses (IOLs). Methods. This is a prospective, consecutive, nonrandomized clinical trial. …”
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Prolonged periods of shallow sleep are associated with diabetic carotid atherosclerosis by Bingge Fan, Lingbing Meng, Lei Bai, Yaping Du, Haiyan Ding, Yu Chen, Yuna Zhang

“…This study aims to investigate the relationship between sleep patterns and carotid atherosclerosis in diabetic patients. Methods Experiments were designed, and Huawei Band 9 bracelets were utilized to monitor the sleep patterns of patients. …”
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Surgical interventions for simple phakic fovea-splitting rhegmatogenous retinal detachment: a comparative study of scleral buckling and pars plana vitrectomy by Haiqin Zhu, Qintuo Pan, Zhaoliang Zhang, Zhaoliang Zhang, Zongduan Zhang, Zongduan Zhang, Xiaoyin Ma, Xiaoyin Ma, Xuting Hu, Xuting Hu

“…AimsTo compare the efficiency of scleral buckling (SB) and pars plana vitrectomy (PPV) with or without SB in patients with primary simple phakic fovea-splitting rhegmatogenous retinal detachment (RRD).MethodsA retrospective case–control study included 101 patients aged <55 years diagnosed with phakic fovea-splitting RRD. …”
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Search for the in-situ production of $$^{77}$$ 77 Ge in the GERDA neutrinoless double-beta decay experiment by M. Agostini, A. Alexander, G. Araujo, A. M. Bakalyarov, M. Balata, I. Barabanov, L. Baudis, C. Bauer, S. Belogurov, A. Bettini, L. Bezrukov, V. Biancacci, E. Bossio, V. Bothe, R. Brugnera, A. Caldwell, S. Calgaro, C. Cattadori, A. Chernogorov, P.-J. Chiu, T. Comellato, V. D’Andrea, E. V. Demidova, N. Di Marco, E. Doroshkevich, M. Fomina, A. Gangapshev, A. Garfagnini, C. Gooch, P. Grabmayr, V. Gurentsov, K. Gusev, J. Hakenmüller, S. Hemmer, W. Hofmann, J. Huang, M. Hult, L. V. Inzhechik, J. Janicskó Csáthy, J. Jochum, M. Junker, V. Kazalov, Y. Kermaïdic, H. Khushbakht, T. Kihm, K. Kilgus, I. V. Kirpichnikov, A. Klimenko, K. T. Knöpfle, O. Kochetov, V. N. Kornoukhov, P. Krause, V. V. Kuzminov, M. Laubenstein, M. Lindner, I. Lippi, A. Lubashevskiy, B. Lubsandorzhiev, G. Lutter, C. Macolino, B. Majorovits, W. Maneschg, G. Marshall, M. Misiaszek, M. Morella, Y. Müller, I. Nemchenok, M. Neuberger, L. Pandola, K. Pelczar, L. Pertoldi, P. Piseri, A. Pullia, C. Ransom, L. Rauscher, M. Redchuk, S. Riboldi, N. Rumyantseva, C. Sada, S. Sailer, F. Salamida, S. Schönert, J. Schreiner, A.-K. Schütz, O. Schulz, M. Schwarz, B. Schwingenheuer, O. Selivanenko, E. Shevchik, M. Shirchenko, L. Shtembari, H. Simgen, A. Smolnikov, D. Stukov, S. Sullivan, A. A. Vasenko, A. Veresnikova, C. Vignoli, K. von Sturm, T. Wester, C. Wiesinger, M. Wojcik, E. Yanovich, B. Zatschler, I. Zhitnikov, S. V. Zhukov, D. Zinatulina, A. Zschocke, K. Zuber, G. Zuzel, GERDA collaboration

“…New digital signal processing methods were employed to select and analyze pile-up signals. …”
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Pedigree investigation and predictive gene testing of the APC gene for colonic adenomatous polyposis by Fang Ruihua, Wang Zhaoming, Qiu Xiaoqian, Zhu Weiye, Ge Sai, Wang Chenglong, Qiu Geng, Gao Xianhua, Xu Xiaodong, Xing Junjie, Wang Hao, Zhang Wei, Yu Enda, Zhao Ziye

“…Subjects for predictive genetic testing included first-degree relatives who could be traced. The testing methods for APC gene encompassed Sanger sequencing, second-generation sequencing, and multiplex ligation-dependent probe amplification. …”
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Differential modification of perceptual thresholds by prolonged near threshold motion in healthy adults and after peripheral lesions by Andrew R. Wagner, Soroush G. Sadeghi, Daniel M. Merfeld, Daniel M. Merfeld, Daniel M. Merfeld, Daniel M. Merfeld

“…., suprathreshold conditioning) would cause an increase in thresholds.MethodsOne-Hz yaw rotation vestibular perceptual thresholds were measured before and immediately after 20-min blocks of passive whole-body motion (i.e., conditioning) in a cohort of 12 healthy adults (27 ± 8.19 years; 10 female). …”
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Surgical long-term outcomes of Hirschsprung Disease in the Democratic Republic of Congo: a case series of 31 patients in a resource-limited setting by Fabrice Gulimwentuga Cikomola, Arsene Daniel Nyalundja, Alliance Wani Bisimwa, Bijoux Safi Matabaro, Franck Masumbuko Mukamba, Costa Musilimu Sudi, Paul Budema Munguakonkwa, Leon-Emmanuel Mukengeshayi Mubenga, Kinja Nyamugabo, Désiré Munyali Alumeti, Théophile Kabesha, Marc Miserez, Dieudonné Mushengezi Sengeyi

“…We aimed at assessing the long-term follow-up outcomes following an innovate resection approach in South Kivu, eastern DRC. Methods In this case series, the authors elucidate the admissions for HD spanning from 2016 to 2021 at a Pediatric Surgical Center in the DRC. …”
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Application of multimodal deep learning in the auxiliary diagnosis and treatment of dermatological diseases by Ting Li, Bowei Li, Yuying Jia, Lian Duan, Ping Sun, Xiaozhen Li, Xiaodong Yang, Hong Cai

“…This review aimed to provide a comprehensive overview of multimodal data and deep learning methods that could help dermatologists diagnose and treat skin diseases.…”
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A rare case of keratitis due to co-infection with Plectosphaerella cucumerina and Acanthamoeba T5 genotype by Anita Raghavan, Jacob Lorenzo-Morales, Maitrayee Kaman Chabra, Shivaprakash Rudramurthy, Narendran Venkatapathy, Siddharth Narendran, Ram Rammohan

“…Aims: This report summarizes clinical findings, diagnosis, management, and long term outcomes of a recalcitrant Plectosphaerella and Acanthamoeba keratitis. Methods and materials: An otherwise healthy male patient presented with a corneal infiltrate with predominantly fungal characteristics, but atypical in terms of progression. …”
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Effect of laser acupuncture on pain, range of motion, and function in patellofemoral pain syndrome: a randomised controlled trial by Nesma M. Allam, Hadeel Alsirhani, Maani Batel Alruwaili, Dalal Mabkhout Dosh, Huriyyah Mislat Alruwaili, Wessal Hisham Almazyad, Rokaia A. Toson, Doaa Ayoub Elimy, Doaa Ayoub Elimy, Mohamed El-Sherbiny, Ateya Megahed Ibrahim, Ateya Megahed Ibrahim, Hasnaa Ali Ebrahim, Nermine Nosseir, Mohamed A. Eladl, Zeinab A. Ali

“…BackgroundPatellofemoral pain syndrome (PFPS) is a knee disorder characterised by pain behind or surrounding the patella that predominantly affects adolescents.ObjectivesThis study aimed to evaluate the impact of laser acupuncture (LA) on pain, range of motion (ROM), and function in patients diagnosed with PFPS.Materials and methodsSixty participants, predominantly young women aged 18–25 years, were randomly distributed into two equal groups: Group A (LA group), which received laser acupuncture (LA) applied to six knee acupoints at 4 J for 80 s/point, in conjunction with an exercise programme; and Group B (Sham LA group), which received LA with the device deactivated, along with an exercise programme including stretching and strengthening exercises. …”
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In vivo keratotomy by mid-infrared femtosecond laser resonant with amide vibrational mode by Jinmiao Guo, Pengfan Chen, Maoxing Xiang, Kan Tian, Zhongjun Wan, Linzhen He, Wenkai Li, Xu Peng, Yujie Peng, Xiangyi Wen, Longqian Liu, Qi Jie Wang, Yuxin Leng, Houkun Liang

“…Electroretinography and visual cliff test are performed for evaluating potential adverse effects on retinal and visual function. …”
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Safety Evaluation in Healthy Adults of Motion-Based Virtual Reality Dichoptic Training for Pediatric Patients With Amblyopia: Prospective Intervention Study by Masakazu Hirota, Yuichi Okumura, Ken Nagino, Takao Hayashi, Takashi Negishi, Shintaro Nakao, Hitoshi Kawasaki, Takenori Inomata

“… Abstract BackgroundAmblyopia, a unilateral or bilateral visual disorder, affects up to 5% of the general population and is a leading cause of childhood visual impairment. …”
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Retinoblastoma research trends from 1980 to 2023: a 44-year bibliometric study by Yun Zhao, Yining Wang, Yuchuan Wang, Yuchuan Wang, Yuchuan Wang, Jiagen Li, Jiagen Li, Hongxun Li, Hongxun Li, Hong Zhao, Hong Zhao, Hong Zhao, Hong Zhao

“…Our objective is to analyze research trends in the RB field and compare contributions from different countries, institutions and authors.MethodsWe extracted all RB-related publications published from 1980 to 2023 from the Web of Science database and applied VOSviewer, R software, Bibliometrix software, Origin 2024 and CiteSpace to review the publication data, analyze the publication trends, and visualize the relevant data. …”
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The inclusion of insect meal from Hermetia illucens larvae in the diet of laying hens (Hy-line Brown) affects the caecal diversity of methanogenic archaea by Tiziana Maria Mahayri, Jakub Mrázek, Fulvia Bovera, Giovanni Piccolo, Giovanni Andrea Murgia, Giuseppe Moniello, Kateřina Olša Fliegerová

“…The effect of the dietary inclusion of Hermetia illucens larvae meal on the diversity of the methanogenic archaea in the caecum of laying hens (Hy-line Brown) was investigated using molecular methods. A total of 27 hens, selected equally for slaughter from 162 birds which were divided equally into 3 treatment groups including control group C with a diet containing corn-soybean meal and 2 experimental groups, HI25 and HI50, in which 25% and 50% of the soybean meal protein was replaced by the protein from a Hermetia illucens larvae meal, respectively. …”
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