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23401
Perceptions of interdisciplinary critical thinking among biology and physics undergraduates
Published 2025-04-01“…However, physics students provided similar definitions of critical thinking in the two disciplines, while biology students provided similar and different definitions in almost equal numbers. The exception was related to the use of quantitative methods solely being associated with critical thinking in physics, despite both critical thinking assessments involving quantitative data analysis. …”
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23402
Evaluation of Nosocomial Infection Management Efficiency Based on the Data Envelopment Analysis Model
Published 2025-04-01“…Jin Wang,1,* Gan Wang,2,3,* Chaoyi Qi4 1Department of Healthcare-associated Infection Management, Qingdao Municipal Hospital, Qingdao, People’s Republic of China; 2Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, People’s Republic of China; 3School of Public Health, Fudan University, Shanghai, People’s Republic of China; 4Department of Anorectal Surgery, Taian Hospital of Traditional Chinese Medicine, Taian, People’s Republic of China*These authors contributed equally to this workCorrespondence: Gan Wang, Email gwangqd@163.comBackground: This study used data envelopment analysis (DEA), to assess relative efficiency of infection control in different clinical departments of the hospital for performance evaluation purposes.Methods: All wards and departments from January to December 2022 were selected as decision units, and five input and two output indicators related to infection prevention and control were determined using DEA. …”
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23403
Construction and Validation of a Nomogram Prediction Model for the Risk of Cefoperazone Sodium/Sulbactam Sodium-Related Coagulation Disorders
Published 2025-08-01“…Mengjun Min,1,* Jing Zeng,1,* Mingyue Zou,1 Yingxian Peng2 1Department of Pharmacy, The Sixth Hospital of Wuhan, Affiliated Hospital of Jianghan University, Wuhan, People’s Republic of China; 2Department of Pharmacy, Hubei No. 3 People’s Hospital of Jianghan University, Wuhan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yingxian Peng, Hubei No. 3 People’s Hospital of Jianghan University, No. 26 Zhongshan Road, Qiaokou District, Wuhan, Hubei, 430033, People’s Republic of China, Email pyx0316@163.comObjective: To construct and validate a nomogram prediction model for the risk of cefoperazone sodium/sulbactam sodium (CPZ/SAM)-related coagulation disorders in hospitalized patients.Methods: Patients treated with CPZ/SAM from January 2022 to December 2024 were enrolled and divided into a coagulation disorder group and a control group based on the occurrence of coagulation disorders. …”
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23404
The Effectiveness of Multimodality Treatment Including Stabilization Splint and Low‐Level Laser Therapies on Managing Temporomandibular Disorders: A Pilot Randomized Controlled Tri...
Published 2025-02-01“…This pilot trial aimed to evaluate the effectiveness of combining stabilization splint therapy (SST) with low‐level laser therapy (LLLT) in managing TMD. Material and Methods This pilot parallel randomized clinical trial included 30 patients with TMD. …”
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23405
Design and initial results of a multi-phase randomized trial of ceftriaxone in amyotrophic lateral sclerosis.
Published 2013-01-01“…Analysis of the pharmacokinetics, tolerability, and safety was used to determine the ceftriaxone dosage for Stage 3 efficacy testing.<h4>Methods</h4>In Stage 1, 66 subjects at ten clinical sites were enrolled and randomized equally into three study groups receiving intravenous placebo, ceftriaxone 2 grams daily or ceftriaxone 4 grams daily divided BID. …”
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23406
Nerve Complications with Regional Anesthesia in Foot and Ankle Surgery Avoiding the Popliteal Fossa
Published 2024-12-01“…An approach to block more distal nerves and avoid the popliteal fossa altogether may provide equal anesthetic and pain relief with fewer motor and sensory complications. …”
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23407
Atelocollagen Injection Enhances the Healing of Nonoperatively Treated Achilles Tendon Tears
Published 2024-12-01“…The purpose of this study is to evaluate the beneficial effects of injected atelocollagen on Achilles tendon healing and investigate the mechanism of atelocollagen on tendon healing. Methods: Percutaneous tenotomy of the right Achilles tendon in 66 rats was performed. …”
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23408
Clinical review of stroke care at National District Hospital, Bloemfontein
Published 2023-01-01“…The study aimed to describe the clinical characteristics, management and outcomes of patients presenting with stroke at NDH. Methods: In this retrospective descriptive study, emergency department registers were used to identify patients presenting with symptoms of a stroke between 01 January 2019 and 31 March 2019. …”
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23409
Clustering analysis of 100-year international seismic catalogue for Azerbaijan
Published 2025-03-01“…Due to this collision activity the seismic pattern of the region is observed with the occurrence of frequent moderate and occasionally strong earthquakes. Research methods. In this study, we used a catalog of International Seismological Centre through the Azerbaijan region including the neighbor parts and aquatory (Caspian Sea). …”
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23410
Tigulixostat Alleviates Hyperuricemic Nephropathy by Promoting M2 Macrophage Polarization
Published 2025-01-01“…Currently, xanthine oxidase (XO) inhibitors are the predominant uric-lowering medications on the market.Methods: In this study, we utilized single-cell RNA sequencing, spatial metabolomics, plasma metabolomics, flow cytometry to explore the effects of Tigulixostat on uric acid level and hyperuricemic nephropathy (HN) in Uox-KO mouse model.Results: In this study, we discovered that Tigulixostat (LC350189) more effectively reduced SUA levels and resulted in better renal outcomes compared to allopurinol, without inducing liver injury in urate oxidase knockout (Uox-KO) mice. …”
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23411
“I Haven’t Told Other People. I Want to Keep My Dignity”: HIV Related Stigma Among the Elderly in Uganda
Published 2024-12-01“…We therefore explored issues related to disclosure of HIV status and HIV-related stigma in the elderly.Patients and Methods: This was an exploratory qualitative study, employing Straussian Grounded Theory. …”
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23412
Intravenous tranexamic acid vs. sublingual misoprostol in high-risk women for postpartum haemorrhage following cesarean delivery; a randomised clinical trial
Published 2023-08-01“…Abstract Objective This study compares the effectiveness of administering sublingual misoprostol combined with oxytocin to that of IV tranexamic acid combined with oxytocin to reduce intra and post-operative blood loss in high-risk women for postpartum haemorrhage (PPH) following cesarean section (CS). Methods About 315 high-risk pregnant women undergoing CS participated in this trial. …”
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23413
Exploring the Predictive Potential of Systemic Immune Inflammation Index and Hematologic Markers in Preterm Labor Risk Assessment
Published 2025-04-01“…Objective: This study aimed to evaluate the potential association between the Systemic Immune Inflammation Index (SII) and preterm labor, given the growing interest in inflammatory biomarkers as possible predictors of pregnancy outcomes. Methods: Conducted as a retrospective observational study at University of Health Sciences Türkiye, Etlik Zübeyde Hanım Women`s Health and Research Hospital, the study included 200 participants, split equally between those with preterm labor and a control group with term births. …”
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23414
Role of RAPID score and adjusted RAPID score in management of infected pleural effusion
Published 2025-04-01“…Aim To assess the role of RAPID score in the detection of successful medical treatment of pleural infection without the need for surgical intervention. Patients and methods An analytical retrospective cross–sectional study for patients diagnosed with infected pleural effusion, both sexes aged above 21 years from those attending Cairo University hospitals, Department of Chest Diseases were included in this study after exclusion of the presence of frank pus, positive gram stain or culture and potential of hydrogen less than 7.2. …”
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23415
Causal Links Between Brain Functional Networks and Endometriosis: A Large-Scale Genetic-Driven Observational Study
Published 2025-02-01“…This study aims to explore these relationships using Mendelian Randomization (MR) analysis.Methods: Data from 191 resting-state functional MRI (rsfMRI) phenotypes and endometriosis genetic datasets were analyzed using both forward and reverse MR approaches. …”
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23416
Global antibiotic dosing strategies in hospitalised children: Characterising variation and implications for harmonisation of international guidelines.
Published 2021-01-01“…We investigated factors underlying variation in antibiotic dosing using data from five global point prevalence surveys.<h4>Methods & findings</h4>Data from 3,367 doses of the 16 most frequent intravenous antibiotics administered to children 1 month-12 years across 23 countries were analysed. …”
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23417
Immediate consecutive microvascular decompression for bilateral classical trigeminal neuralgia
Published 2024-11-01“…Microvascular decompression (MVD) is a well-established treatment for TN; however, the experience with immediate consecutive bilateral MVD procedures is limited and requires further evaluation.ObjectiveTo evaluate the safety and efficacy of immediate consecutive bilateral MVD in patients with severe BTN compared to non-consecutive bilateral MVD procedures.MethodsA retrospective analysis was conducted on 15 patients with BTN who underwent bilateral MVD. …”
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23418
Risky sexual behaviour amidst predicament of acceptable sexually transmitted infection partner notification modalities: A cross-sectional survey amongst minibus taxi drivers in Gau...
Published 2020-12-01“…This study assessed the perceived use of patient-initiated PN by using referral slips and measured the level of acceptability of provider-initiated PN by using short message service (SMS) to the personal mobile phones of sexual partners. Methods: A formative evaluation approach using a quantitative survey amongst 722 minibus taxi drivers in nine major taxi ranks in Tshwane Municipality, Gauteng Province. …”
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23419
Atopic Dermatitis and Psoriasis as Overlapping Syndromes
Published 2020-01-01“…This study aimed to present the clinical and immunological profiles of patients with concomitant AD and PS and compare them with those of patients with only one of the diseases. Methods. In this observational study, 38 children with concomitant AD and PS with a mean age of 6.5±3.2 yrs were compared with 41 similar patients with AD only (5.3±5.1 yrs) and 28 patients with PS only (6.4±4.3 yrs). …”
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23420
Hand-arm vibration and the risk of vascular and neurological diseases-A systematic review and meta-analysis.
Published 2017-01-01“…Moreover the aim was to estimate the magnitude of such an association using meta-analysis.<h4>Methods</h4>This systematic review covers the scientific literature up to January 2016. …”
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