Could the Injury Severity Score be a new indicator for surgical treatment in patients with traumatic splenic injury? by HyeJeong Jeong, SungWon Jung, Tae Gil Heo, Pyong Wha Choi, Jae Il Kim, Sung Min Jung, Heungman Jun, Yong Chan Shin, Eunhae Um

“…Purpose The purpose of this study was to determine whether a higher Injury Severity Score (ISS) could serve as an indicator of splenectomy in patients with traumatic splenic lacerations. Methods A total of 256 cases of splenic laceration were collected from January 1, 2005 to December 31, 2018. …”
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Acetylsalicylic acid and vorapaxar are less active, while 4-methylcatechol is more active, in type 1 diabetic patients compared to healthy controls by Markéta Paclíková, Lukáš Konečný, Alejandro Carazo, Kateřina Matoušová, Lenka Kujovská Krčmová, Vladimír Blaha, Alena Šmahelová, Přemysl Mladěnka

“…Abstract Introduction It is well known that platelets from diabetic patients can be resistant to clinically used antiplatelet drugs. Methods To assess the phenomenon in more detail, 50 adult patients suffering from type 1 diabetes mellitus (T1D) were recruited and their responses to 7 platelet aggregation inducers, as well as to 3 clinically used antiplatelet drugs (acetylsalicylic acid /ASA/, ticagrelor and vorapaxar) and one experimental compound, 4-methylcatechol, were assessed ex vivo. …”
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Does Gender Impact Intensity of Care Provided to Older Medical Intensive Care Unit Patients? by Kathleen M. Akgün, Terrence E. Murphy, Katy L. B. Araujo, Peter H. Van Ness, Margaret Pisani

“…No documented studies evaluate whether men and women are treated equally in the medical intensive care unit (MICU). …”
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Is European current climate regulation strategy feasible? A comparative analysis of “Fit for 55” green transition package for V4 and LEU4 by Jacek Brożyna, Jintao Lu, Wadim Strielkowski

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Topical clindamycin for acne vulgaris: analysis of gastrointestinal events by Natalia M. Pelet del Toro, Andrew Strunk, Jashin J. Wu, Linda Stein Gold, James Q. Del Rosso, Robert T. Brodell, George Han

“…This review provides background information and an overview of safety data of topical clindamycin for treating AV.Materials and Methods: Available safety data from published literature, previously unpublished worldwide pharmacovigilance data, and two retrospective cohort studies were reviewed.Results and Conclusions: According to pharmacovigilance data, the rate of GI adverse drug reactions with topical clindamycin-containing products was 0.000045% (64/141,084,533). …”
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Optimizing Energy Efficiency in UPA-Assisted SWIPT Massive MIMO Systems Over Rician Fading Channels by Mohammad Hassan Adeli, Dariush Abbasi-Moghadam, Hossein Fotouhi, S. Mohammad Razavizadeh

“…The Results also indicate a considerably higher growth rate on EE by increasing the number of antennas and Rician factors compared to the two other methods.…”
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Efficacy of adding ketamine to levobupivacaine in paravertebral block on acute and chronic pain in thoracotomy: a randomized controlled double-blinded trial by Saad Ahmed Moharam, Amgad Elshikh, Mohamed Abdelbadie, Ahmed Mohamed Ibrahim, Mostafa Mohamed Khedr Shaheen, Mohammed Said ElSharkawy

“…This work aimed to evaluate the effect of adding ketamine to TPVB on thoracotomy-related acute and chronic pain. Methods:. This randomized controlled double-blinded trial included 60 patients scheduled for open thoracotomy. …”
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Bilateral Variability of Quadriceps Angle and Impact of Height on it in Female Population of Uttarakhand by Chanchal Sharma, Sadakat Ali, Rubina Victor, Brijesh Thakur

“…The left and right legs are not always equal. Females tend to have a larger angle than men due to a broader pelvis. …”
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Neurological and psychological aspects of scleroderma of the face and neck in children by M. S. Pavlova, L. G. Khachatryan, M. K. Osminina, N. A. Geppe, N. S. Podchernyaeva, V. M. Trepilets, M. D. Bogdanova, E. V. Kasanave, E. N. Tjurina, M. D. Velikoretskaya

“…The list of mandatory examination methods for scleroderma of the face and neck should include brain MRI, EEG and psychological examination.…”
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Efficacy of 2‐Mercaptoethane Sulfonate Sodium (MESNA) in the Prevention of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography: A Randomized Open Label Trial by Amir Sadeghi, Hesamoddin Samar, Mohammad Abbasinazari, Parvaneh Mohammadi, Ali Abazarikia, Shadi Ziaie

“…The present clinical trial evaluated whether adding intravenous mesna to rectal indomethacin could prevent or alleviate PEP. Methods An open‐labeled clinical trial was done on 698 participants undergoing endoscopic retrograde cholangiopancreatography (ERCP). …”
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Community Urinary Tract Infections: Guideline Adjustment by Carina Lopes Cunha, Andreia M. Costa, Maria João Brandão, Hugo Lopes, Isabel Neves, Valquíria Alves

“…Our objective was to identify the most frequent microorganisms present in urine cultures in Primary Health Care, at a Local Health Unit and their sensitivity profile to some antibiotics. Methods: Observational and retrospective study based on bacteriological identification in urine cultures obtained between January/2020 and December/2021. …”
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Irisin: An influential perspective on the protective effect of metformin on aortic and cardiac aging in rats by Ozgur Baris, Gulcin Gacar, Burak Acar, Feride Ipek Komsuoglu Celikyurt, Yusufhan Yazir, Tijen Utkan

“…The predictive value of irisin for the effects of metformin on cardiac and aortic aging in an aged rat model was evaluated by quantitative and histological confirmation. Material and Methods: A total of twenty-four rats were used in our study. …”
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Pegylated Interferon-α Modulates Liver Concentrations of Activin-A and Its Related Proteins in Normal Wistar Rat by Bassem Refaat, Adel Galal El-Shemi, Ahmed Mohamed Ashshi, Elaf Wael Mahamid, Noha Mohammed Al-Qadi

“…To measure the expression of activin βA-subunit, activin IIA and IIB receptors, Smad4, Smad7, and follistatin in the liver and the liver and serum concentrations of mature activin-A and follistatin in normal rat following treatment with pegylated interferon-α (Peg-INF-α) and ribavirin (RBV). Materials and Methods. 40 male Wistar rats were divided equally into 4 groups: “control,” “Peg-only” receiving 4 injections of Peg-INF-α (6 µg/rat/week), “RBV-only” receiving ribavirin (4 mg/rat/day) orally, and “Peg & RBV” group receiving both drugs. …”
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Facial Expression Overrides Lumbopelvic Kinematics for Clinical Judgements about Low Back Pain Intensity by A. Courbalay, T. Deroche, M. Descarreaux, E. Prigent, J. O'Shaughnessy, M.-A. Amorim

“…Results showed that experienced clinicians relied equally on FEI and LK to estimate pain, whereas novice clinicians mostly relied on FEI. …”
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A Comparative Study of Deep Audio Models for Spectrogram- and Waveform-Based SingFake Detection by Minh Nguyen-Duc, Luong Vuong Nguyen, Huy Nguyen-Ho-Nhat, Tri-Hai Nguyen, O-Joun Lee

“…Our findings contribute to developing more effective deepfake singing detection methods, with implications for security, media authentication, and digital content protection.…”
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MALDI-TOF Mass Spectrometry as the Tool for the Identification of Features of Polymers Obtained by Inverse Vulcanization by Natalia Tarasova, Efrem Krivoborodov, Diana Kirakosian, Alexey Zanin, Ilya Toropygin, Yaroslav Mezhuev

“…Consequently, the registration and interpretation of MALDI-TOF spectra of inverse vulcanization products, either independently or in conjunction with the application of ¹H and ¹³C NMR spectroscopy methods, as well as the determination of the limiting number of sulfur atoms that can be bound to one molecule of an unsaturated compound, paves the way for new avenues of investigation into the structure and side reactions involved in the synthesis of high-sulfur polymers.…”
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Socio-economic disparities in prenatal prognosis and intervention accessibility by Simona Raluca Iacoban, Madalina Piron-Dumitrascu, Camil Laurentiu Bohiltea, Ioan Dumitru Suciu, Silviu Cristian Voinea, Nicolae Suciu

“…This study aimed to assess the impact of socio-economic factors on prenatal care accessibility and outcomes and to evaluate the effectiveness of specialized integrative prenatal care in mitigating these disparities. Materials and Methods. A prospective cohort study was conducted between 2020 and 2023 in Bucharest, Romania, involving 100 pregnant women. …”
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Racial (In)Equity in South Los Angeles—Community Centered Experiences with COVID-19 Syndemics by Dilara K. Üsküp, Yelba M. Castellon-Lopez, Oluwadamilola Jolayemi, Cheryl A. Branch, Oladunni Adeyiga, Steve Shoptaw

“…Objectives: To analyze community experiences involving COVID-19 vaccination access and equity in Black and Latina/o/x communities within South Los Angeles, using a socioecological framework. Methods: We conducted four virtual focus groups (n = 33 total participants) in 2021, with Black and Latina/o/x community members, community leaders, and community-based providers in South Los Angeles, a region highly impacted by the COVID-19 pandemic. …”
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Identification of novel potential hypoxia-inducible factor-1α inhibitors through machine learning and computational simulations by Yuxiang He, Shuning Diao, Shengzhen Hou, Taiying Li, Wenhui Meng, Jinping Zhang

“…IntroductionHypoxia-inducible factor-1α (HIF-1α) has become a significant therapeutic target for breast cancer and other cancers by regulating the expression of downstream genes such as erythropoietin, thereby improving cell survival in hypoxic conditions.MethodsWe jointly applied a multistage screening system encompassing machine learning, molecular docking, and molecular dynamics simulations to conduct virtual screening of the “Traditional Chinese Medicine Monomer Library” for potential HIF-1α inhibitors. …”
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Effect of Recycling Protocol on Mechanical Strength of Used Mini-Implants by Sérgio Estelita, Guilherme Janson, Kelly Chiqueto, Eduardo Silveira Ferreira

“…This study evaluated the influence of recycling process on the torsional strength of mini-implants. Materials and Methods. Two hundred mini-implants were divided into 4 groups with 50 screws equally distributed in five diameters (1.3 to 1.7 mm): control group (CG): unused mini-implants, G1: mini-implants inserted in pig iliac bone and removed, G2: same protocol of group 1 followed by sonication for cleaning and autoclave sterilization, and G3: same insertion protocol of group 1 followed by sonication for cleaning before and after sandblasting (Al2O3-90 µ) and autoclave sterilization. …”
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