Preovulatory uterine flushing with saline as a treatment for unexplained infertility: a randomised controlled trial protocol by Lynne Moore, Jessica Lefebvre, Sarah Maheux-Lacroix, Marie-Ève Bergeron, Emmanuel Bujold, Sylvie Dodin

“…Our objective is to assess the efficacy of preovulatory uterine flushing with physiological saline for the treatment of unexplained infertility.Methods and analysis We will perform a randomised controlled trial based on consecutive women aged between 18 and 37 years consulting for unexplained infertility for at least 1 year. …”
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Serum Lipid Profile of Newly Diagnosed Hypertensive Patients in Nnewi, South-East Nigeria by Charles U. Osuji, Emeka G. Omejua, Emmanuel I. Onwubuya, Gladys I. Ahaneku

“…The objective of this study was to examine the serum lipid patterns of newly diagnosed hypertensive patients attending a tertiary healthcare centre in South East Nigeria. Methods. Two hundred and fifty newly diagnosed adult hypertensive patients and an equal number of age- and sex-matched controls without hypertension were consecutively recruited from the Medical and General Outpatient Clinics of Nnamdi Azikiwe University Teaching Hospital, Nnewi. …”
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Compulsive sexual behavior disorder: rates and clinical correlates in a community sample by Jon E. Grant, Sophie Boutouis, Madison Collins, Samuel R. Chamberlain, Samuel R. Chamberlain

“…BackgroundThis study sought to examine the rate of compulsive sexual behavior disorder (CSBD) in a sample of adults drawn from the community and its associated mental health correlates.MethodsAn online survey of “Personality, Mental Health, and Well-Being” was distributed via Prolific to 300 adults aged 18 to 75 years. …”
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Diagnostic Yield of Next-Generation Sequencing for Rare Pediatric Genetic Disorders: A Single-Center Experience by Milena Stoyanova, Dinnar Yahya, Mari Hachmeriyan, Mariya Levkova

“…However, its success rate varies based on the underlying genetic etiology and the population studied. <b>Methods</b>: This retrospective study evaluated the diagnostic yield of NGS in a cohort of 137 pediatric patients with suspected rare genetic disorders in Bulgaria, a setting where such testing is not reimbursed and must be self-funded. …”
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Inhibitory Effect of Exosomes Loaded with Ginsenoside Rh2 on Growth of Hepatocellular Carcinoma Cells by Meile LI, Ziyue ZHAO, Kai JIN, Yu’an XIE

“…ObjectiveTo explore the effects of exosomes loaded with ginsenoside Rh2 on the biological functions of hepatocellular carcinoma cells. MethodsBoth Huh7 and PLC/PRF/5 cell were equally divided into control group, exosome group (Exos group), drug group (G-Rh2 group), and exosomes-loaded-with-ginsenoside Rh2 group (Exos@G-Rh2 group). …”
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Incidence rate of different forms of idiopathic childhood focal epilepsy by K. Yu. Mukhin, M. B. Mironov, . ., . ., . ., . ., . ., . .

“…Their age enabled to monitor the debut of seizures. The methods of investigation included clinical examination, video EEG-monitoring, testing by neuropsychologist and, when necessary, neurovisualization. …”
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Effect of early versus standard central line removal on growth of very low birthweight premature infants: a protocol for a non-inferiority randomised controlled trial by Paweł Krajewski, Justyna Romańska, Wojciech Margas, Joanna Seliga-Siwecka

“…The aim of this study is to determine whether earlier central line removal is non-inferior to its removal after reaching full enteral intake, in respect to growth outcome of preterm infants.Methods and analysis Very low birthweight premature infants will be recruited. …”
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Hydrogen and syngas production from gasification of lignocellulosic biomass in supercritical water media by Farid Safari, Ahmad Tavasoli, Abtin Ataei, Jun-Ki Choi

“…The purpose of this study is to investigate the production of hydrogen-rich syngas from wheat straw, walnut shell, and almond shell. Methods Supercritical water gasification is a promising technology to convert biomass into useful fuels. …”
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Challenges to ethical public engagement in research funding: a perspective from practice [version 2; peer review: 2 approved, 1 approved with reservations] by Neelke Doorn, Martijn Wiarda, Kalli Giannelos

“…To address these challenges, we propose the following seven interventions: (1) developing comprehensive recruitment strategies with experienced recruiters and community organizations; (2) establishing clear communication of roles, expectations, and outcomes through codes of conduct; (3) training mediators to address power imbalances; (4) designing flexible engagement methods and providing tailored support; (5) implementing collaborative feedback loops for inclusive funding call formulation; (6) enhancing ethical standards through internal expertise and external advisory inputs; and (7) developing adaptive strategies for flexible and ethical public engagement. …”
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Effect of industrial processing of crackers on the recovery and quantitation of allergens with ELISA kits by Cindy Hidalgo-Víquez, Rebeca López-Calvo, Adrián Roda-Brenes, Carolina Cortés-Herrera, Andrea Chacón

“…To determine the effect of processing on the recovery and quantification of allergens. Materials and methods. Study conducted in Costa Rica between 2020 and 2021 in the Compañía de galletas Pozuelo DCR. …”
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Breast silicone explant: a multicenter longitudinal study by Denis Souto Valente, William Massami Itikawa, Fabiana Catherino, Ricardo Votto, Anne Groth

“…This study aims to analyze the historical symptoms and ascertain breast explant patients’ impressions at three different times: before breast implant placement while having the implants, and after the explant surgery. Methods: This survey was designed as a multicenter longitudinal observational study using an online voluntary participation questionnaire sent by e-mail. …”
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The Axial Length of the Eyeball and Bioelectrical Activity of Masticatory and Neck Muscles: A Preliminary Report by Grzegorz Zieliński, Michał Baszczowski, Maria Rapa, Anna Matysik-Woźniak, Magdalena Zawadka, Jacek Szkutnik, Piotr Gawda, Robert Rejdak, Piotr Majcher, Michał Ginszt

“…The present study aimed to evaluate the correlation of eye length and bioelectric activity of temporalis, masseter, digastric, and sternocleidomastoid muscles in women with myopia compared to healthy women. Methods. Based on the exclusion and inclusion criteria, 42 women aged 24 years (±2 years) were eligible for the study. …”
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A Comparison of Intralesional Triamcinolone Acetonide Injection for Primary Chalazion in Children and Adults by Jacky W. Y. Lee, Gordon S. K. Yau, Michelle Y. Y. Wong, Can Y. F. Yuen

“…To investigate outcome differences of intralesional triamcinolone acetonide (TA) injection for primary chalazia in children versus adults. Methods. A retrospective review of consecutive subjects with primary chalazion who received intralesional TA injection was conducted. …”
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Two-Hour Lactate Clearance Predicts Negative Outcome in Patients with Cardiorespiratory Insufficiency by Sean Scott, Vittorio Antonaglia, Giovanna Guiotto, Fiorella Paladino, Fernando Schiraldi

“…Emergency Department (ED) and 16-bed medical High Dependency Unit (HDU). Methods and Main Results. 95 consecutive admissions from the ED for acute cardiorespiratory insufficiency were prospectively enrolled. …”
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Finite‐temperature properties of NbO2 from a deep‐learning interatomic potential by Xinhang Li, Yongqiang Wang, Tianyu Jiao, Zhaoxin Liu, Chuanle Yang, Ri He, Liang Si

“…These findings elucidate the structural and dynamical mechanisms underlying the structural properties of NbO2 and highlight the utility of combining DFT and deep potential MD methods for studying complex phase transitions in transition metal oxides.…”
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Analysing EU Countries’ Digital Progress Towards Sustainable Development Goals by Alexandra-Nicoleta Ciucu (Durnoi), Cosmin Alexandru Teodorescu, Vanesa Madalina Vargas, Corina Ioanas

“…The next step carried out in the current article was to conduct a three-year forecast of the indicators listed previously. The methods used to make predictions are Autoregressive Integrated Moving Average (ARIMA) and Double Exponential Smoothing. …”
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Impact of Active Case Finding on Treatment Outcomes in Adult Pulmonary Tuberculosis Patients by S. А. Sterlikov, V. B. Gаlkin, B. M. Mаliev, А. А. Shirokovа, V. А. Khorotetto, А. S. Mаyzhegishevа

“…The objective: to assess the effect of active finding of tuberculosis cases on the frequency of bacterial excretion, lung tissue destruction, and treatment outcomes.Subjects and Methods. The characteristics of adult patients (newly detected - new cases and those with relapsed pulmonary tuberculosis) were studied in 2 phases: a) 1,404 cases, including 814 actively found, at detection; b) the outcomes of the completed first course of chemotherapy in 946 patients, including 565 actively detected, registered for treatment in 2017 and 2018. …”
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Decision-making process of tomatoes purchase by generation Z: case study in the Slovak Republic by Michaela Šugrova, Marek Plachy, Ľudmila Nagyova, Jozef Šumichrast

“…The accuracy of provided hypotheses was verified using the following mathematical-statistical methods: Chi-Square test of independence, Mann-Whitney U-test, and as Chi test for equality of proportions between two samples. …”
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Combination of Clopidogrel and Nicorandil Improves Post-Procedure Platelet Activation and Cardiac Function Impairment in Patients with Acute Coronary Syndrome Undergoing PCI by Zhenhao Cai, Jie Zhao, Xiang Zhang, Changpeng Zuo, Wei Zhang

“…The effects of nicorandil combined with clopidogrel on platelet activation and cardiac function injury in patients with ACS after PCI were examined. Methods 174 patients with ACS receiving PCI were equally divided into control group (taking clopidogrel before PCI) and active group (nicorandil and clopidogrel in combination before PCI). …”
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Among Ectasia Patients with Coexisting Coronary Artery Disease, TIMI Frame Count Correlates with Ectasia Size and Markis Type IV Is the Commonest by Hasahya Tony, Kai Meng, Bangwei Wu, Qiutang Zeng

“…In ectasia patients, there is delayed coronary flow with increased TFC. Methods. We evaluated angiograms of 789 patients for presence of CAE, coronary artery disease (CAD), and Markis type of CAE. …”
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