Recent advances in dual response molecular probes for biothiols by Master Mwafulirwa, Khamis Abdalla, Wenhai Bian, Hongbei Wei, Liren Xu, Wanyi Yu, Zhang Hui, Qi Yang, Xiaolong Sun

“…We examine design techniques, sensing mechanisms, and imaging methods to assess their effectiveness and responsiveness to thiols. …”
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Deep multi-view feature fusion with data augmentation for improved diabetic retinopathy classification by Boualleg Yaakoub, Daouadi Kheir Eddine, Guehairia Oussama, Djeddi Chawki, Cheddad Abbas, Siddiqi Imran, Bouderah Brahim

“…The results demonstrate that our architecture significantly improves classification accuracy, surpassing existing methods. Our contributions highlight a promising approach for enhancing DR classification performance.…”
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An online intervention relationship enhancement couple therapy program versus systematic desensitization on sexual performance anxiety in women undergoing infertility treatment wit... by Maryam Afzal Dehkordi, Tahmineh Farajkhoda, Mahdi Khanabadi, Farimah Shamsi

“…Objective: This study aimed to compare the effectiveness of relationship enhancement couple therapy program (RECT) vs. systematic desensitization (SD) on sexual anxiety. Materials and Methods: A parallel randomized clinical trial was conducted on 68 women with infertility in Shahrekord, Iran, in January 2022. …”
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A comparative study of analgesic effect between ultrasound-guided posterior vis-a-vis lateral transversus abdominis plane block in patients undergoing total abdominal hysterectomy... by Rajib Sikder, Sankar Roy, Arunava Biswas, Dipasri Bhattacharya

“…Aims and Objectives: This study was done to compare the analgesic effect of posterior TAP block and lateral TAP block in TAH+BSO. Materials and Methods: A double-arm observational study was conducted on eighty patients (ASA 1 and 2) posted for TAH+BSO under spinal anesthesia. …”
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A Bibliometric Study of Interleukin Cytokines in the Treatment of Intervertebral Disc Degeneration by Wang H, Li X, Wang S, Liu J, Xie N

“…Systematic analysis of interleukin family cytokines and intervertebral disc degeneration and summary of related mechanisms will help to further promote the progress of related clinical treatment.Methods: The related articles published in 1 January 2015– 1 December 2024 were all from network science (WOS), and charts were made and analyzed by using social science statistics software package and GraphPad Prism 8 software. …”
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Heterogeneity in diabetic distal neuropathy and differential approach to its treatment by Oksana Evgen'evna Khutornaya, Vadim Borisovich Bregovskiy, A G Demina, I A Karpova

“…AIMS: To determine the prevalence of painful diabetic neuropathy (PDN), to evaluate the composition and efficacy of pharmacotherapy and to develop a differential algorithm for symptomatic treatment of PDN. MATERIALS AND METHODS: 4494 outpatient subjects participated in this study. …”
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Dynamic neurocognitive adaptation: A follow‐up exposome investigation in aging by Filippo Cieri, Chad Lee Cross, Giulia Di Francesco, Jessica Zoe Kirkland Caldwell

“…METHODS We used the dynamic Neurocognitive Adaptation (dNA) scale, our validated tool to explore protective factors in AD, in 410 older adult participants (50% women). …”
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Application of the 2021 AAPOS Guidelines in Clinics with Revision and Validation of SPOT Referral Criteria by Li R, Yan Q, Lin X, Wu Z, Zhu H, Guo W, Zhang P, Zuo F, Wu Z, Liu H, Huang D

“…Rui Li,1,* Qi Yan,2,* Xiao Lin,3,* Zhujian Wu,4 Hui Zhu,4 Wei Guo,4 Peibin Zhang,4 Feidi Zuo,5 Ziyan Wu,5 Hu Liu,4 Dan Huang4 1Department of Ophthalmology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People’s Republic of China; 2Department of Ophthalmology, Children’s Hospital of Soochow University, Suzhou, People’s Republic of China; 3Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA; 4Department of Ophthalmology, the First Affiliated Hospital with Nanjing Medical University, Nanjing, People’s Republic of China; 5The Fourth School of Clinical Medicine of Nanjing Medical University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hu Liu; Dan Huang, Department of Ophthalmology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, People’s Republic of China, Tel +86 (25) 68136470, Fax +86 (25) 83275171, Email liuhu@njmu.edu.cn; huangdan@njmu.edu.cnPurpose: This study aims to validate and revise the Spot Vision Screener referral criteria for detecting amblyopia risk factors (ARFs), visually significant refractive error (VSRE), and amblyopia.Methods: In clinics, we gathered data from children aged 12 months to 7 years. …”
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Neutrophils in Rheumatoid Arthritis Synovium: Implications on Disease Activity and Inflammation State by Deng Y, Li J, Wu R

“…This finding suggests that neutrophil involvement in RA pathogenesis is not universal but subtype-specific, potentially linked to distinct clinical phenotypes.Methods: We performed a retrospective analysis of synovial pathology and clinical data from 55 RA patients collected during 2023. …”
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Comparison of Two Manual Therapy Programs, including Tendon Gliding Exercises as a Common Adjunct, While Managing the Participants with Chronic Carpal Tunnel Syndrome by Fauzia Javed Sheereen, Bibhuti Sarkar, Pallavi Sahay, Mohammad Abu Shaphe, Ahmad H. Alghadir, Amir Iqbal, Taimul Ali, Fuzail Ahmad

“…This study aimed to compare the efficacy of the neurodynamic technique (NT) and carpal bone mobilization technique (CBMT) incorporated with tendon gliding exercises (TGE) as an effect-enhancing adjunct while managing the participants with chronic CTS. Methods. The study followed a two-arm parallel-group randomized comparative design. …”
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Oxidative Stress in Dry Eye Disease: A Bibliometric Analysis by Lei Y, Huang XY, Guo H, Huang R, Shi Y, Hong J, Yang Y, Ma X

“…Yifan Lei,1,* Xin Yun Huang,1,* Haodong Guo,1 Rongqing Huang,1 Yajun Shi,1 Jue Hong,1 Yanting Yang,1,2 Xiaopeng Ma1,2 1Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yanting Yang, Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, 650 Wanping South Road, Shanghai, 200030, People’s Republic of China, Email tcmyyt@126.com Xiaopeng Ma, Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, 650 Wanping South Road, Shanghai, 200030, People’s Republic of China, Email pengpengma@163.comPurpose: To study the knowledge structure and evolution of oxidative stress in dry eye disease (DED) using bibliometrics and explore prospective anti-oxidative stress strategies for future clinical interventions.Methods: The Web of Science Core Collection (WoSCC) was used as the data source to systematically retrieve and screen the research literature published between January 1, 1992, and December 31, 2024, related to oxidative stress research in DED. …”
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Ultrasonic Bone Scalpel in Anterior Cervical Discectomy and Fusion Enhances Outcomes and Foraminal Decompression in Cervical Radiculopathy: A Retrospective Cohort Study by Peng Z, Xiong Y, Jia Y, Li J, Liu Z, Wang G

“…No significant differences in complication rates, including dural tears or nerve root injuries, were found between the two groups.Conclusion: The ultrasonic bone scalpel-assisted decompression technique offers significant advantages over traditional methods in terms of surgical outcomes, including better pain relief, functional recovery, and foraminal enlargement, while maintaining comparable safety profiles.Keywords: ultrasonic bone scalpel, anterior cervical discectomy and fusion, ACDF, foraminotomy, smallest oblique sagittal area…”
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Single-Injection Adductor Canal Block Enhances Early Mobilization with Comparable Analgesia to Continuous Infusion in Unicompartmental Knee Arthroplasty: A Retrospective Cohort Stu... by Lan F, Chong Y, Liu F, Wang T

“…However, the comparative benefits of single-injection ACB (SACB) versus continuous ACB (CACB) remain unclear.Methods: In our retrospective cohort study, patients undergoing unilateral, primary UKA were allocated to group CACB or group SACB from January 2016 to December 2023. …”
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The efficacy of training on the four quadrant brain processes on cognitive functions of students with mathematical disorders by zohreh sadat moeini, farnaz Keshavarzi Arshadi, Masoud Gholam Ali Lavasani, SAEED hasanzadeh

“…Aims: This research aims to investigate the effectiveness of training on the four quadrant brain processes on the cognitive functions of students with mathematical learning disorders. Methods: This study falls into the category of semi-experimental research with a pre-test-post-test design and follow-up, using a matched group. …”
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Articaine Needle - Free Anesthesia Vs Conventional Anesthesia in Root Canal Treatment of Irreversible Pulpitis in Permanent Teeth: A Prospective Study on Anesthetic Efficacy and Ef... by Qian S, Meng Z, Zhang H, Li K, Zhang F, Zhang S, Liu J, Zhou Z

“…Suhui Qian,1,* Ziying Meng,2,* Haiyan Zhang,1 Kaicheng Li,1 Fei Zhang,1 Sen Zhang,1 Jianfei Liu,1 Zhou Zhou1 1Department of Stomatology, Huaibei People’s Hospital, Huaibei, Anhui, People’s Republic of China; 2Stomatology Department of Suixi County Hospital, Huaibei, Anhui, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhou Zhou, Email Zz178685@163.comObjective: This study aimed to compare the anesthetic efficacy of articaine needle-free anesthesia with conventional lidocaine nerve block anesthesia for root canal treatment in permanent teeth with irreversible pulpitis.Methods: In this prospective clinical trial, 94 patients were randomly allocated to receive either articaine needle-free anesthesia (n=47) or lidocaine nerve block anesthesia (n=47). …”
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Health Literacy, Label Comprehension, and Consumer Perceptions of Quasi-Drug Information Among Korean Adults: A Cross-Sectional Study by Ko Y, Kim HJ, Lee SM

“…This study aimed to evaluate HL and its impact on comprehending quasi-drug labels, assess consumer perceptions of key label elements and their perceived importance, and provide actionable recommendations for improving label design and health communication.Methods: An online cross-sectional survey of 500 Korean adults (aged 20– 69) was conducted in September 2023 using proportionate stratified sampling based on the 2020 Korean Census. …”
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Model-Informed Precision Dosing of Remimazolam in General Anesthesia Patients by Chen Y, Zhang ZJ, Zhang XF, Peng Y, Jiao Z, Wu JX

“…Yueting Chen,1,* Zuo-Jing Zhang,2,* Xiao-Feng Zhang,2 Yuan Peng,2 Zheng Jiao,1,* Jing-Xiang Wu2,* 1Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Department of Anesthesiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zheng Jiao, Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, People’s Republic of China, Email jiaozhen@online.sh.cn Jing-Xiang Wu, Department of Anesthesiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Xuhui District, Shanghai, 200030, People’s Republic of China, Tel +86 021-22200000-3302, Fax +86 021-32260806, Email wjx1132@163.comPurpose: This study aimed to characterize the pharmacokinetics/pharmacodynamics (PK/PD) of remimazolam in patients under general anesthesia using a population analysis and to develop a web-based dashboard tool that directly displays the optimal dosing regimen for general anesthesia.Patients and Methods: A total of 20 patients received remimazolam for general anesthesia, during which intensive arterial blood samples and bispectral index (BIS) values were collected. …”
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A Nomogram Model for Predicting Recurrent Coronary Thrombosis in Kawasaki Disease Patients by Zhou X, Peng Y, Yi Q

“…However, there are currently no studies predicting the recurrence of coronary thrombosis, so the aim of this study was to develop and validate a nomogram to predict recurrent coronary thrombosis in KD patients.Methods: This was a retrospective study of data from 149 KD patients who had a history of previous coronary disease at the Children’s Hospital of Chongqing Medical University from 2013 to 2020. …”
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Efficacy of Selective Nerve Root Block for Different Types of Lumbar Disc Herniation: Study Protocol for a Single-Blind, Prospective Cohort Study by Tan H, Zhou J, Pu Y, He L, Wang L

“…This study aims to evaluate the clinical efficacy of SNRB in treating various LDH subtypes, classified according to the Michigan State University (MSU) classification system, and to explore its potential as a safe and minimally invasive percutaneous treatment option.Methods: This is a single-blind, Prospective Cohort Study. …”
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Central Serous Chorioretinopathy from the Point of View of OCT-Angiography. Part 1. Chorioretinal Blood Flow Changes by A. G. Shchuko, S. I. Zhukova, T. N. Iureva, A. N. Zlobina

“…Purpose: to reveal the regularities of the change in the choroidal blood flow in patients with SCR according to the OCTA data, to assess their informativeness and role in the pathogenesis of the disease. Patients and methods: 26 patients with SCR aged 35–54 years were examined. …”
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