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    Protocol for differentiation of human embryonic stem cells into surface epithelium and functional keratinocytes by Jiafeng Liu, Huaxing Huang, Hong Ouyang

    Published 2025-09-01
    “…Here, we present a protocol to differentiate human embryonic stem cells (hESCs) into SE and subsequently into epidermal keratinocyte progenitors. …”
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    Functionality of endothelial cells differentiated from porcine epiblast stem cells, bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells by Yeon-Ji Lee, In-Won Lee, Tae-Suk Kim, Bo-Gyeong Seo, Sang-Ki Baek, Cheol Hwangbo, Joon-Hee Lee

    Published 2024-12-01
    “…The purpose of this study was to induce the differentiation of porcine epiblast stem cells (pEpiSCs), bone marrow-derived mesenchymal stem cells (pBM-MSCs) and adipose-derived mesenchymal stem cells (pA-MSCs) into ECs and then examine the functionality of vascular ECs. …”
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    MicroRNA functions in osteogenic differentiation of periodontal ligament stem cells: a scoping review by Pirawish Limlawan, Pirawish Limlawan, Anjalee Vacharaksa, Anjalee Vacharaksa, Anjalee Vacharaksa

    Published 2025-01-01
    “…This scoping review aimed to describe the differential microRNA (miRNA) functions in osteogenic differentiation of periodontal ligament stem cells (PDLSCs), and then analyze the potential of applying PDLSCs and miRNAs in bone regeneration. …”
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    Role of Toll-Like Receptors in Actuating Stem/Progenitor Cell Repair Mechanisms: Different Functions in Different Cells by Fabio Sallustio, Claudia Curci, Alessandra Stasi, Giuseppe De Palma, Chiara Divella, Roberto Gramignoli, Giuseppe Castellano, Anna Gallone, Loreto Gesualdo

    Published 2019-01-01
    “…In this review, we analyze the many different functions that the TLRs assume in SCs, pointing out that they can have different effects, depending on the background and on the kind of ligands that they recognize. …”
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    Extremely low-frequency electromagnetic fields facilitate proliferation and functional differentiation in spinal neural stem cells by Wenxu Tang, Dan He, Xiaofei Li, Yi Feng, Yue Xu, Jiawei Hu, Wei Xu, Lei Xue

    Published 2025-08-01
    “…Abstract Traumatic spinal cord injury (SCI), typically resulting from direct mechanical damage to the spine, often leads to disruption of neural signaling and axonal conduction, severely impairing nervous system function. In rodent models of SCI, neural stem cell (NSC) transplantation has demonstrated significant potential in restoring motor function and enhancing neural repair. …”
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    Regulation of stem cell fate and function by using bioactive materials with nanoarchitectonics for regenerative medicine by Wei Hu, Jiaming Shi, Wenyan Lv, Xiaofang Jia, Katsuhiko Ariga

    Published 2022-12-01
    “…Besides multipotent differentiation, immunomodulation is an important biological function of mesenchymal stem cells (MSCs). …”
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    Cardiac Differentiation of Pluripotent Stem Cells by Kristiina Rajala, Mari Pekkanen-Mattila, Katriina Aalto-Setälä

    Published 2011-01-01
    “…The ability of human pluripotent stem cells to differentiate towards the cardiac lineage has attracted significant interest, initially with a strong focus on regenerative medicine. …”
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    Dental pulp stem cells conditioned medium-functionalized microspheres for endodontic regeneration by Jing Gao, Jing Gao, Yuhan Wang, Yuhan Wang, Tongxing Zhang, Jiafei Qu, Jiafei Qu, Qian Liu, Yao Chen, Yao Chen, Baoshan Xu, Jing Shen, Jing Shen

    Published 2025-07-01
    “…However, recreating the native pulp microenvironment remains a critical challenge.MethodsThis study developed a novel strategy to mimic the dental pulp regeneration microenvironment using nucleus pulposus microspheres (NPM) loaded with conditioned medium (CM) for dental pulp stem cells (DPSCs). The biocompatibility of NPM and the effects of NPM-loaded CM on DPSCs differentiation and angiogenesis were systematically evaluated. …”
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    Uncoupling protein 2 and 4 expression pattern during stem cell differentiation provides new insight into their putative function. by Anne Rupprecht, Dana Sittner, Alina Smorodchenko, Karolina E Hilse, Justus Goyn, Rudolf Moldzio, Andrea E M Seiler, Anja U Bräuer, Elena E Pohl

    Published 2014-01-01
    “…To verify this hypothesis, we analyzed the expression of UCP1-5 in mouse embryonic stem cells before and after their differentiation to neurons. …”
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    PTPN21 Overexpression Promotes Osteogenic and Adipogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells but Inhibits the Immunosuppressive Function by Huafang Wang, Xiaohang Ye, Haowen Xiao, Ni Zhu, Cong Wei, Xiang Sun, Limengmeng Wang, Binsheng Wang, Xiaohong Yu, Xiaoyu Lai, Shan Fu, He Huang

    Published 2019-01-01
    “…In the study, we explored the effects of PTPN21 on human bone marrow-derived mesenchymal stem cells (BM-MSCs) via lentiviral-mediated overexpression and knock-down of PTPN21 in vitro. …”
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    Highly efficient generation of mature megakaryocytes and functional platelets from human embryonic stem cells by Chuxin Chen, Ning Wang, Xueyan Zhang, Yingjie Fu, Zhiyong Zhong, Haibin Wu, Yaming Wei, Yuyou Duan

    Published 2024-11-01
    “…Abstract Background Platelet transfusion therapy has made a great breakthrough in clinical practice, and the differentiation of human embryonic stem cells (hESCs) to produce functional platelets has become a new potential approach, however, efficient generation of functional platelets still faces great challenges. …”
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    The Multifaceted Roles of MicroRNA-181 in Stem Cell Differentiation and Cancer Stem Cell Plasticity by Chun Yang, Rui Wang, Pierre Hardy

    Published 2025-01-01
    “…Stem cells are undifferentiated or partially differentiated cells with an extraordinary ability to self-renew and differentiate into various cell types during growth and development. …”
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