Identification and experimental validation of ulcerative colitis-associated hub genes through integrated WGCNA and lysosomal autophagy analysis by Yuanpei Zhao, Yijun Li, Qingwen Xu, Lili Ding, Weiming Li, Qinghua Zou, Yichen Hu, Kaiwen Shi, Hongyuan Liu

“…Immune cell infiltration of these gene sets was evaluated using the CIBERSORT algorithm. Lysophagy-related genes set were retrieved from the GeneCards database. …”
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VisME: Visual microsaccades explorer by Tanja Munz, Lewis L. Chuang, Sebastian Pannasch, Daniel Weiskopf

“…Even when the same algorithms are employed, different parameter values might be adopted across different studies. …”
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A systematic review of data privacy in Mobility as a Service (MaaS) by Zineb Garroussi, Antoine Legrain, Sébastien Gambs, Vincent Gautrais, Brunilde Sansò

“…Using the PRISMA framework, a comprehensive literature search across Web of Science, Elsevier, and IEEE Xplore databases resulted in the selection of 32 studies for detailed analysis.The review is structured around three main themes: (1) Privacy-Preserving Techniques, including anonymization strategies (k-anonymity, differential privacy, obfuscation), encryption methods (blockchain, cryptographic protocols), federated learning for decentralized data processing, and advanced algorithms for optimizing privacy budgets and balancing utility-privacy trade-offs; (2) User Trust and Privacy Perceptions, highlighting that trust in service providers is essential for MaaS adoption, privacy concerns may impact adoption but do not necessarily prevent it (the “privacy paradox”), and awareness of data misuse affects user trust and willingness to adopt MaaS; and (3) Regulatory Frameworks, focusing on the importance of GDPR compliance to ensure strict data protection through consent and transparency, and embedding privacy-by-design principles within MaaS architectures to safeguard user data from the outset.This review emphasizes the need for a holistic approach, integrating technological innovation, user-centered design, and strong regulatory oversight to effectively address privacy challenges in MaaS. …”
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Disrupted fetal carbohydrate metabolism in children with autism spectrum disorder by Serena B. Gumusoglu, Brandon M. Schickling, Donna A. Santillan, Lynn M. Teesch, Mark K. Santillan

“…Untargeted principle components analysis of all metabolites did not reveal group differences, while targeted biomarker assessment (using only Fructose 6-phosphate, D-Mannose, and D-Fructose) by a Random Forest algorithm generated an area under the curve (AUC) = 0.766 (95% CI: 0.612–0.896) for ASD prediction. …”
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Effective Prediction on Time Series Data Using Deep Learning: An Incisive Review by Rupa Rajakumari, Ujwal Ambadas Lanjewar

“…Time-series evaluation explores the way in which data differs over time and optimal prediction could determine the pathway wherein the data seems to be changing. …”
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Edges are all you need: Potential of medical time series analysis on complete blood count data with graph neural networks. by Daniel Walke, Daniel Steinbach, Sebastian Gibb, Thorsten Kaiser, Gunter Saake, Paul C Ahrens, David Broneske, Robert Heyer

“…Finally, we discovered that feature slope and importance highly differ between trained algorithms (e.g., XGBoost and GNN) on the same data basis.…”
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Metabolomic Profiling Reveals Serum Tryptophan as a Potential Therapeutic Target for Systemic Lupus Erythematosus by Wang K, Zhu R, Xu M, Zhu K, Li J, Li C, Meng D, Chen H, Sun L

“…Kai Wang,1,2 Rujie Zhu,1 Min Xu,3 Kexin Zhu,1 Ju Li,2 Chang Li,4 Deqian Meng,2 Hongwei Chen,1,3,5 Lingyun Sun1,5 1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, 210008, People’s Republic of China; 2Department of Rheumatology and Immunology, The Affiliated Huai’an No.1 People’s Hospital of Nanjing Medical University, Huai’an, 223001, People’s Republic of China; 3Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, People’s Republic of China; 4Department of Medical Laboratory, The Affiliated Huai’an No.1 People’s Hospital of Nanjing Medical University, Huai’an, 223001, People’s Republic of China; 5Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, People’s Republic of ChinaCorrespondence: Lingyun Sun, Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Zhongshan Road 321, Nanjing, 210008, People’s Republic of China, Email lingyunsun@nju.edu.cn Hongwei Chen, Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, People’s Republic of China, Email chenhw@nju.edu.cnObjective: This study aimed to identify potential diagnostic biomarkers for systemic lupus erythematosus (SLE) using metabolomics approaches and machine learning algorithms, and to evaluate therapeutic targets for SLE treatment.Methods: Serum samples from 44 SLE patients with lupus nephritis, 40 rheumatoid arthritis patients, 39 primary Sjögren’s syndrome patients, and matched healthy controls were analyzed using ultra-performance liquid chromatography-high resolution mass spectrometry (UPLC-HRMS). …”
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Comment on “Odontogenic Tumors: A Challenge for Clinical Diagnosis and an Opportunity for AI Innovation” by Hinpetch Daungsupawong, Viroj Wiwanitkit

“…Additionally, a more thorough exploration of the current limitations in diagnosing these tumors would have provided a more comprehensive understanding of the issue.Moving forward, future research should focus on developing AI algorithms that can accurately differentiate between different types of odontogenic tumors based on their unique characteristics. …”
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Effects of Drought and Fire Severity Interaction on Short-Term Post-Fire Recovery of the Mediterranean Forest of South America by Ana Hernández-Duarte, Freddy Saavedra, Erick González, Alejandro Miranda, Jean-Pierre Francois, Marcelo Somos-Valenzuela, Jason Sibold

“…Using the LandTrendr algorithm, we assessed post-fire forest recovery based on NDVI changes between pre-fire values and subsequent years. …”
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Computed Tomography‐Based Habitat Analysis for Prognostic Stratification in Colorectal Liver Metastases by Chaoqun Zhou, Hao Xin, Lihua Qian, Yong Zhang, Jing Wang, Junpeng Luo

“…An unsupervised K‐means clustering algorithm classified the tumors into two clusters based on their habitat characteristics. …”
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Automated satellite remote sensing of giant kelp at the Falkland Islands (Islas Malvinas). by Henry F Houskeeper, Isaac S Rosenthal, Katherine C Cavanaugh, Camille Pawlak, Laura Trouille, Jarrett E K Byrnes, Tom W Bell, Kyle C Cavanaugh

“…Using the remote sensing approaches evaluated herein, we present the first continuous timeseries of giant kelp observations in the FLK region using Landsat imagery spanning over three decades. …”
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Private Data Incrementalization: Data-Centric Model Development for Clinical Liver Segmentation by Stephanie Batista, Miguel Couceiro, Ricardo Filipe, Paulo Rachinhas, Jorge Isidoro, Inês Domingues

“…However, these models often face challenges in adapting to diverse clinical data sources as differences in dataset volume, resolution, and origin impact generalization and performance. …”
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Validity of the International Classification of Diseases 10th revision code for hospitalisation with hyponatraemia in elderly patients by Amit X Garg, Salimah Z Shariff, Sonja Gandhi, Jamie L Fleet, Matthew A Weir, Arsh K Jain

“…Objective To evaluate the validity of the International Classification of Diseases, 10th Revision (ICD-10) diagnosis code for hyponatraemia (E87.1) in two settings: at presentation to the emergency department and at hospital admission.Design Population-based retrospective validation study.Setting Twelve hospitals in Southwestern Ontario, Canada, from 2003 to 2010.Participants Patients aged 66 years and older with serum sodium laboratory measurements at presentation to the emergency department (n=64 581) and at hospital admission (n=64 499).Main outcome measures Sensitivity, specificity, positive predictive value and negative predictive value comparing various ICD-10 diagnostic coding algorithms for hyponatraemia to serum sodium laboratory measurements (reference standard). …”
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Modeling the Electricity Generation Processes of a Combined Solar and Small Hydropower Plant by Mykola Dyvak, Volodymyr Manzhula, Andriy Melnyk, Nataliia Petryshyn, Tiande Pan, Arkadiusz Banasik, Piotr Pikiewicz, Wojciech M. Kempa

“…A methodology is proposed for evaluating the joint operation of a solar power plant and a small hydropower plant. …”
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Computer guided versus freehand dental implant surgery: Randomized controlled clinical trial by Nermine Ramadan Mahmoud, Mohamed Hatem Kamal Eldin, Mai Hassan Diab, Omar Samy Mahmoud, Yasser El-Sayed Fekry

“…A secondary aim is to propose an algorithm for predicting the accuracy of implant placement. …”
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Revealing key regulatory factors in lung adenocarcinoma: the role of epigenetic regulation of autophagy-related genes from transcriptomics, scRNA-seq, and machine learning by Xianchang Zeng, Lingyun Wei, Lu Lv, Di Wu, Yingying Shen, Xinliang Lu, Xianghui Kong, Zhijian Cai, Jianli Wang, Jianli Wang

“…Single-cell RNA sequencing was further employed to evaluate the heterogeneity of immune cells. Machine learning algorithms were utilized to construct and identify diagnostic markers for LUAD, which were then validated by receiver operating characteristic (ROC) curve analysis. …”
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Integrated DDPG-PSO energy management systems for enhanced battery cycling and efficient grid utilization by Oladimeji Ibrahim, Mohd Junaidi Abdul Aziz, Razman Ayop, Wen Yao Low, Nor Zaihar Yahaya, Ahmed Tijjani Dahiru, Temitope Ibrahim Amosa, Shehu Lukman Ayinla

“…The results show that the integrated DDPG-PSO EMS outperforms the traditional DDPG in terms of battery scheduling and grid utilization efficiency. Cost evaluations under critical peak tariffs indicate that both EMS algorithms achieved a 34 % cost saving compared to a grid-only system. …”
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Enhancing Corn Image Resolution Captured by Unmanned Aerial Vehicles With the Aid of Deep Learning by Emilia Alves Nogueira, Bruno Moraes Rocha, Gabriel da Silva Vieira, Afonso Ueslei da Fonseca, Juliana Paula Felix, Antonio Oliveira-Jr, Fabrizzio Soares

“…In future investigations, we hope to refine the accuracy of the proposed approaches, as well as expand the comparisons with other super-resolution algorithms. In addition, tests will be carried out with different datasets, including satellite images, to evaluate the specificity in apply these techniques in different scenarios. …”
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Sound-Based Unsupervised Fault Diagnosis of Industrial Equipment Considering Environmental Noise by Jeong-Geun Lee, Kwang Sik Kim, Jang Hyun Lee

“…The DANN evaluated interdomain similarity using cosine similarity, enabling the accurate classification of fault states in the target domain. …”
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Impact of antibiotic-loaded bone cement prophylaxis on infection rates after curettage and cementation for bone tumor by Sermsak Sukpanichyingyong, Thanate Poosiripinyo, Krits Salang, Saksin Simsin

“…Background: Infection rates post-surgery differ markedly between routine orthopaedic procedures and bone tumor surgeries, the latter significantly raising morbidity rates. …”
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