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501
Gene Profiling of Aortic Valve Interstitial Cells under Elevated Pressure Conditions: Modulation of Inflammatory Gene Networks
Published 2011-01-01“…Linear, two-cycle amplification of total RNA, followed by microarray was performed for transcriptome analysis (with qRT-PCR validation). …”
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502
Cytogenomic characterization of mosaic X-ring chromosomes in seventeen patients with Turner syndrome (TS)-42 years of experience at a single-site institution
Published 2025-04-01“…Current guidelines recommend karyotype as the first-line test rather than SNP microarray analysis when aneuploidy is suspected. Conventional cytogenetics is still necessary to understand structural abnormalities, provide genomic context, and detect low-level mosaicism. …”
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503
Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology
Published 2009-06-01“…We collected protein and mRNA expression data through shot‐gun proteomics and microarray expression analysis of the highly vascular exchange region, microdissected from the human and mouse near‐term placenta. …”
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504
A very rare case of a newborn with tetrasomy 9p and literature review
Published 2022-02-01“…Microarray analysis revealed 38,584 kb tetrasomic region at 9p24.3p13.1. …”
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505
Informative value of rapid microbiological diagnostic tests and experience in studying a procalcitonin assay in the evaluation of the activity of a mycobacterial population in chil...
Published 2015-01-01“…Drug resistance in MBT was determined by a microarray test in only 16 (23.5%) out of 68 patients for lack or paucity of DNA in the diagnostic material. …”
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506
Association between a specific monocyte subset and heart failure with preserved ejection fraction in patients with uremia
Published 2025-01-01“…Conclusions: Specific gene detections can be an important early warning indicator and guide physicians in evaluating the risk of HFpEF in ESRD.…”
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507
TLR3 Plays Significant Roles against HBV-Associated HCC
Published 2015-01-01“…The apoptosis of tumor cells was also detected by TUNEL stain. Correlations between TLR3 expression and HBV infection, interstitial immunoreactive cells, and cells apoptosis in HCC were investigated. …”
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508
A long non-coding RNA lncRNA-PE promotes invasion and epithelial–mesenchymal transition in hepatocellular carcinoma through the miR-200a/b-ZEB1 pathway
Published 2017-05-01“…However, the detailed mechanisms underlying their activities are not fully understood. Using microarray technology, a number of long non-coding RNAs were previously identified to be aberrantly expressed in hepatocellular carcinoma. …”
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509
iSubgraph: integrative genomics for subgroup discovery in hepatocellular carcinoma using graph mining and mixture models.
Published 2013-01-01“…We defined a method to transform microarray data into graph representation that encodes miRNA and gene expression levels and the interactions between them as well. …”
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510
Immortalized Human Schwann Cell Lines Derived From Tumors of Schwannomatosis Patients.
Published 2015-01-01“…Cell morphology was retained following multiple passaging and freeze/ thaw cycles. Gene expression microarray analysis was used to compare the cell lines with their respective parent tumors. …”
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511
Ubiquitin Specific Protease 26 (USP26) expression analysis in human testicular and extragonadal tissues indicates diverse action of USP26 in cell differentiation and tumorigenesis.
Published 2014-01-01“…Immunofluorescence colocalization studies were performed with formalin-fixed/paraffin-embedded and frozen tissues using primary and secondary antibodies to detect USP26 and AR protein expression. Human microarray dot blots were used to identify protein expression in extra-gonadal tissues. …”
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512
Molecular diagnosis of Usher syndrome: application of two different next generation sequencing-based procedures.
Published 2012-01-01“…We analyzed a total of 12 patients, most of which were negative for previously described mutations in known USH genes upon primer extension-based microarray genotyping. We enriched the NGS template either by whole exome capture or by Long-PCR of the known USH genes. …”
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513
Neutrophil Extracellular Traps Drive Kidney Stone Formation
Published 2025-01-01“… Introduction: This study aims to explore the contribution of neutrophil extracellular traps (NETs) to kidney stones. Methods: The microarray data from GSE73680 and bioinformatic analysis were applied to identify differentially expressed genes in patients with kidney stones. …”
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514
Transcriptomics of the interaction between the monopartite phloem-limited geminivirus tomato yellow leaf curl Sardinia virus and Solanum lycopersicum highlights a role for plant ho...
Published 2014-01-01“…Here we present the first microarray study of transcriptional changes induced by the phloem-limited geminivirus TYLCSV infecting tomato, its natural host. …”
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515
Alternative splicing of NURF301 generates distinct NURF chromatin remodeling complexes with altered modified histone binding specificities.
Published 2009-07-01“…By comparing microarray expression profiles and phenotypes of null Nurf301 mutants with mutants that remove the C-terminal PHD fingers and bromodomain, we show that full-length NURF301 is not essential for correct expression of the majority of NURF gene targets in larvae. …”
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516
Global gene expression profiling of myeloid immune cell subsets in response to in vitro challenge with porcine circovirus 2b.
Published 2014-01-01“…Furthermore, PCV2 has been detected in bone-marrow samples, potentially enabling an easy spread and reservoir for the virus. …”
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517
The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer.
Published 2011-01-01“…In order to obtain a global view of the impact of Snail and Slug expression, we performed a microarray experiment using the MCF-7 breast cancer cell line, which does not express detectable levels of Snail or Slug. …”
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518
Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome-associated coronavirus infection.
Published 2010-01-01“…Thus, a comprehensive evaluation of the complex epithelial signaling to SARS-CoV is crucial for paving the way to better understand SARS pathogenesis. Based on microarray-based functional genomics, we report here the global gene response of 2B4 cells, a cloned bronchial epithelial cell line derived from Calu-3 cells. …”
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519
Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate.
Published 2011-01-01“…In addition, GRFT appears to retain antiviral activity once bound to the surface of PBMC. Finally, RNA microarray studies show that, while CV-N and ConA regulate expression of a multitude of cellular genes, GRFT treatment effects only minimal alterations in the gene expression profile of a human ectocervical cell line. …”
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520
Evaluating IL22RA1 expression as a predictive indicator in human colon cancer progression
Published 2025-08-01“…Methods In this study, we utilized a multi-color immunohistochemistry (mIHC) assay to examine the expression patterns of IL22RA1, IL22, CD155, and IL22BP in a tissue microarray (TMA) comprising 90 colon cancer samples. …”
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