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421
Pan-cancer analysis identifies CD155 as a promising target for CAR-T cell therapy
Published 2025-06-01“…Targeting CD155 with CAR-T cells provides an effective approach to treating both solid and hematologic malignancies.…”
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422
Profiling of gastric cancer cell-surface markers to achieve tumour–normal discrimination
Published 2020-12-01“…Promising candidates from this analysis were validated orthogonally using multispectral immunohistochemistry (mIHC) with automated quantitative analysis using the Vectra platform. mIHC was performed on a tissue microarray containing matched normal, marginal and tumour tissues. …”
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423
Transcriptional response to deletion of the phosphatidylserine decarboxylase Psd1p in the yeast Saccharomyces cerevisiae.
Published 2013-01-01“…To study the genome wide effect of an unbalanced cellular and mitochondrial PE level and in particular the contribution of Psd1p to this depletion we performed a DNA microarray analysis with a ∆psd1 deletion mutant. …”
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424
Nanofiber Alignment Regulates NIH3T3 Cell Orientation and Cytoskeletal Gene Expression on Electrospun PCL+Gelatin Nanofibers.
Published 2016-01-01“…A microarray of cyotoskeleton regulators was probed to examine differences in gene expression between cells grown on an aligned and randomly oriented substrates. …”
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425
Establishing an induced pluripotent stem cell bank using urine cells from pediatric patients with neurogenetic diseases
Published 2025-08-01“…The genomic stability of the iPSCs was assessed using chromosomal microarray (CMA). Results UCs were successfully isolated from patients with various early-onset neurogenetic diseases and reprogrammed into iPSCs. …”
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426
The Functions and Mechanism of a New Oligopeptide BP9 from Avian Bursa on Antibody Responses, Immature B Cell, and Autophagy
Published 2019-01-01“…These results suggested that BP9 might be a strong bursal-derived active peptide on antibody response, B cell differentiation, and autophagy in immature B cells, which provided the linking among humoral immunity, B cell differentiation, and autophagy and offered the important reference for the effective immunotherapeutic strategies and immune improvement.…”
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427
Integrated analysis of hub genes and intrinsically disordered regions in triple-negative breast cancer
Published 2024-12-01“…Two microarray datasets were used to identify possible targets for TNBC, GSE38959 and GSE45827, retrieved from the Gene Expression Omnibus (GEO) database. …”
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428
Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma.
Published 2016-01-01“…A microarray expression analysis and functional annotation of differentially expressed genes identified several biological pathways where serglycin may be important. …”
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429
Integration of the transcriptome and glycome for identification of glycan cell signatures.
Published 2013-01-01“…The model further elucidated limitations in the two analytical platforms including a defect in the microarray for detecting the GnTV (MGAT5) enzyme. Our results demonstrate the potential of systems glycobiology tools for elucidating key glycan biomarkers and potential therapeutic targets. …”
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430
Inhibition of ATG5-mediated autophagy maintains PMAIP1 stability to promote cell apoptosis and suppress triple-negative breast cancer progression
Published 2025-05-01“…Methods TNBC-related datasets were retrieved from The Cancer Genome Atlas and selected by Prediction Analysis of Microarray 50 analysis to assess the expression of PMAIP1 in the samples. …”
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431
Exosomal miR-93-3p targets EIF4EBP1 to regulate macrophage polarization and accelerate wound healing post-anal fistula surgery
Published 2025-08-01“…Total RNA was extracted through the TRIzol method, followed by miRNA microarray analysis to identify differentially expressed miRNAs (DEMs). …”
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432
Peroxisome proliferator-activated receptor gamma coactivator-1 alpha acts as a tumor suppressor in hepatocellular carcinoma
Published 2017-04-01“…In addition, the expression levels of 21,400 genes in tissues and cells were detected by microarray. It was shown that peroxisome proliferator-activated receptor gamma coactivator-1 alpha expression was significantly downregulated in hepatocellular carcinoma compared with normal liver tissues. …”
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433
Gene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver
Published 2010-01-01“…Thiazolidinediones are a class of Peroxisome Proliferator Activated Receptor γ (PPARγ) agonists that reduce insulin resistance in type 2 diabetic patients. Although no detectable hepatic toxicity has been evidenced in animal studies during preclinical trials, these molecules have nevertheless induced hepatic adverse effects in some treated patients. …”
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434
Clinical case of distal arthrogryposis in combination with epilepsy due to an unbalanced translocation
Published 2022-07-01“…This clinical observation demonstrates an opportunity of using innovative molecular cytogenetic technologies in the search for disease-related genetic causes in the absence of mutations detected by whole exome sequencing.…”
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435
A retrospective analysis of 6942 amniocentesis cases
Published 2025-08-01“…Among the single-method cases, Chromosomal Microarray Analysis (CMA) was the most frequently selected technique (14.18%). …”
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436
Comprehensive computational analysis reveals H5N1 influenza virus-encoded miRNAs and host-specific targets associated with antiviral immune responses and protein binding.
Published 2022-01-01“…H5N1 virus (H5N1V) is highly contagious among birds and it was first detected in humans in 1997 during a poultry outbreak in Hong Kong. …”
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437
The Correlation Analysis Between m6A Methylation Modification and Ferroptosis Induced by Cigarette Smoke in Human Bronchial Epithelium
Published 2024-12-01“…The ROS, GSH, MDA, and total iron content were detected by relevant detection kits. The expression levels associated with ferroptosis and m6A methylation modification‐related genes were determined via reverse transcription‐quantitative polymerase chain reaction and western blot. …”
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438
Noninvasive prediction of fetal growth restriction using maternal plasma cell-free RNA: a case-control study
Published 2025-07-01“…Differentially expressed genes (DEGs) between FGR and controls groups were identified through the analysis of cell-free RNA and placental microarray dataset which downloaded from the Gene Expression Omnibus database. …”
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439
Integrated analysis of genomic and transcriptomic profiles identified a prognostic immunohistochemistry panel for esophageal squamous cell cancer
Published 2020-01-01“…Abstract Background The poor outcome of patients with esophageal squamous cell carcinoma (ESCC) highlights the importance of the identification of novel effective prognostic biomarkers. We aimed to identify a clinically applicable prognostic immunohistochemistry (IHC) panel for ESCC. …”
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440
ASSOCIATION OF THE COMBINATION OF STEMNESS GENE AMPLIFICATIONS AND COPY NUMBER ABERRATIONS OF WNT-SIGNALING GENES IN BREAST TUMORS WITH METASTASIS
Published 2020-07-01“…The tumor DNA was examined using a CytoScanHD Array microarray (Affymetrix, USA).Results. By subtracting amplification and deletion frequencies in 852 cytobands between groups with metastases and without metastases, 21 cytobands were identified with the largest difference in deletion and amplification frequencies. …”
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