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361
Identification of potential biomarkers for 2022 Mpox virus infection: a transcriptomic network analysis and machine learning approach
Published 2025-01-01“…This study aimed to identify the differentially expressed genes (DEGs) induced by the 2022 MPXV infection through comprehensive bioinformatics analyses of microarray and RNA-Seq datasets from post-infected cell types with different MPXV clades. …”
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362
Integrating single-cell RNA sequencing, WGCNA, and machine learning to identify key biomarkers in hepatocellular carcinoma
Published 2025-04-01“…Abstract The microarray and single-cell RNA-sequencing (scRNA-seq) datasets of hepatocellular carcinoma (HCC) were downloaded from the Gene Expression Omnibus (GEO) database. …”
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363
A novel computational approach for predicting complex phenotypes in Drosophila (starvation-sensitive and sterile) by deriving their gene expression signatures from public data.
Published 2020-01-01“…We utilised available microarray gene-expression data for two phenotypes (starvation-sensitive and sterile) in Drosophila. …”
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364
Amogel: a multi-omics classification framework using associative graph neural networks with prior knowledge for biomarker identification
Published 2025-03-01“…Abstract The advent of high-throughput sequencing technologies, such as DNA microarray and DNA sequencing, has enabled effective analysis of cancer subtypes and targeted treatment. …”
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365
Global gene expression profiling reveals SPINK1 as a potential hepatocellular carcinoma marker.
Published 2013-01-01“…Six genes identified by microarray as highly expressed in HH-HCC were confirmed by RT qPCR. …”
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366
Distinctive profile of IsomiR expression and novel microRNAs in rat heart left ventricle.
Published 2013-01-01“…The expression of known miRNAs in the heart has been studied at length by microarray and quantitative PCR but it is becoming evident that microRNA isoforms (isomiRs) are potentially physiologically important. …”
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367
TRIM22 promotes glioblastoma development by ubiquitinating Bcl-2
Published 2025-12-01“…A TRIM22-overexpressing ubiquitination microarray identified TRIM22 as a potential activator of Bcl-2. …”
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368
Predictive and prognostic significance of loss of heterozygosity in ABC transporter genes in breast cancer
Published 2022-11-01“…Material and methods. a total of 130 breast cancer patients were included in the study. microarray analysis was performed on Affymetrix Cytoscantm HD Array high-density DNA chips to assess LOH status. …”
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369
Enhanced leukemia prediction using hybrid ant colony and ant lion optimization for gene selection and classification
Published 2025-06-01“…The proposed model, which identifies the optimal feature set for classification using Support Vector Machine (SVM), has achieved an impressive prediction accuracy of 93.94 %. Results on microarray datasets for leukemia prediction show that the hybrid approach outperforms other methods in terms of both effectiveness and efficiency. …”
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370
FAM111B knockdown attenuates tumorigenesis of ovarian cancer via the downregulation of MYC
Published 2025-08-01“…Immunohistochemical analyses conducted on tissue-microarray samples obtained from patients with serous ovarian cancer indicated that elevated levels of FAM111B expression were associated with unfavorable prognostic outcomes. …”
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371
Bioinformatics and network pharmacology-based study to elucidate the multi-target pharmacological mechanism of the indigenous plants of Medina valley in treating HCV-related hepato...
Published 2023-06-01“…Following that, this study combines network pharmacology with bioinformatics approaches to potentially revolutionize HCV-related HCC treatment by identifying effective phytochemicals of indigenous plants of Medina valley. …”
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372
Global challenges and solutions to achieving and sustaining measles and rubella elimination
Published 2024-12-01“…Progress will be supported through technological innovations such as microarray patch vaccines. Whether this holistic approach will be more effective than vertical initiatives at achieving measles and rubella elimination remains to be seen. …”
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373
Investigation on the Electron Emission Regularity of Sputtered Boron Nitride Thin Films and Microstructured Array Surfaces
Published 2025-03-01“…The results of laser etching on the BN bulk surface to form microarray structures show that the EEC of BN bulk decreases significantly with the increase of the average aspect ratio of the microstructures. …”
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374
Poly-β-D-(1,6)-N-acetyl-glucosamine (PNAG) glycan vaccines with broad spectrum neutralizing activities
Published 2025-07-01“…Glycan microarray analysis shows that dPNAG glycans with DP8 and DP12 are optimal, with corresponding protein conjugates eliciting the highest IgG titers. …”
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375
Genetic testing for oral clefts: reflections based on a single Brazilian public genetics service
Published 2025-08-01“…They also show the need to improve public health policies for genetic evaluation, diagnostic tests, and genetic counseling for an effective NPCCPRD.…”
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376
Comparative Study of PPARγ Targets in Human Extravillous and Villous Cytotrophoblasts
Published 2020-01-01“…Visualizations were prepared in Cytoscape. From our microarray data, 139 DEGs were detected in rosiglitazone-treated EVCTs (RT-EVCTs) and 197 DEGs in rosiglitazone-treated VCTs (RT-VCTs). …”
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377
Identification of Novel Molecular Panel as Potential Biomarkers of PAN-Gastrointestinal Cancer Screening: Bioinformatics and Experimental Analysis
Published 2025-07-01“…In the present study, using integrated transcriptomics, RNA-Seq and microarray data, from the TCGA and GEO databases, respectively, were combined to discover and validate a global biomarker panel for PAN-gastrointestinal cancers. …”
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378
Metformin inhibits high glucose‐induced apoptosis of renal podocyte through regulating miR‐34a/SIRT1 axis
Published 2024-01-01“…A conditionally immortalized human podocyte cell line was cultivated in d‐glucose (30 mM). Results Microarray and RT‐qPCR revealed that miR‐34a was downregulated in HG‐treated podocytes. …”
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379
Prenatal Diagnosis of Fetal Visceral Situs Abnormalities: A Retrospective Study
Published 2025-07-01“…Moreover, for fetuses diagnosed with visceral situs abnormalities and pregnant women with normal chromosomal results, WES remains essential to improve the detection rates of PCD or other genetic abnormalities.…”
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380
Potential role of SLC6A3 in neurodevelopmental impairments associated with corpus callosum abnormalities: insights from CNV analysis and clinical phenotyping
Published 2025-08-01“…Methods From January 2021 to July 2023, 13 children with MRI-confirmed CCAs underwent chromosomal microarray analysis (CMA) for CNV detection. We performed bioinformatic analyses (Gene Ontology, STRING network) to identify neurodevelopmental genes within pathogenic CNVs, and clinical follow up assessed neurobehavioral outcomes. …”
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