Complement factor H in molecular regulation of angiogenesis by Li Jiang, Wang Kaili, Starodubtseva Maria N., Nadyrov Eldar, Kapron Carolyn M., Hoh Josephine, Liu Ju

Subjects: “…complement factor h…”
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Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility. by Jian Zhao, Hui Wu, Melanie Khosravi, Huijuan Cui, Xiaoxia Qian, Jennifer A Kelly, Kenneth M Kaufman, Carl D Langefeld, Adrienne H Williams, Mary E Comeau, Julie T Ziegler, Miranda C Marion, Adam Adler, Stuart B Glenn, Marta E Alarcón-Riquelme, BIOLUPUS Network, GENLES Network, Bernardo A Pons-Estel, John B Harley, Sang-Cheol Bae, So-Young Bang, Soo-Kyung Cho, Chaim O Jacob, Timothy J Vyse, Timothy B Niewold, Patrick M Gaffney, Kathy L Moser, Robert P Kimberly, Jeffrey C Edberg, Elizabeth E Brown, Graciela S Alarcon, Michelle A Petri, Rosalind Ramsey-Goldman, Luis M Vilá, John D Reveille, Judith A James, Gary S Gilkeson, Diane L Kamen, Barry I Freedman, Juan-Manuel Anaya, Joan T Merrill, Lindsey A Criswell, R Hal Scofield, Anne M Stevens, Joel M Guthridge, Deh-Ming Chang, Yeong Wook Song, Ji Ah Park, Eun Young Lee, Susan A Boackle, Jennifer M Grossman, Bevra H Hahn, Timothy H J Goodship, Rita M Cantor, Chack-Yung Yu, Nan Shen, Betty P Tsao

“…Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins (CFHR1-CFHR5) within the chromosome 1q32 locus linked to SLE, have been associated with multiple human diseases and may contribute to dysregulated complement activation predisposing to SLE. …”
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Glycoproteomics analysis of complement factor H and its complement-regulatory function during Streptococcus pneumoniae-associated hemolytic uremic syndrome by Laura M. Baas, Kioa L. Wijnsma, Fokje Zijlstra, Nicole C. A. J. van de Kar, Lieke ter Steeg, Antonia H. M. Bouts, Marloes A. H. M. Michels, Marloes A. H. M. Michels, Jeroen D. Langereis, Dirk Lefeber, Dirk Lefeber, Hans J. C. T. Wessels, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel

Subjects: “…complement factor H…”
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Clinical values of serum Gd-IgA1， complement factor H and complement regulatory proteins in IgA nephropathy by Zou Mei, Xue Hen, Lu Fang-cao, Zheng Guang-yi, Zhao Min

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The specific contributions of factor H and factor I in controlling fluid phase activation of the alternative complement pathway by Nancy A. Turner, Joel L. Moake

“…Abstract The immediate defense provided by the alternative complement pathway (AP) is under constant control by fluid phase regulators, factor H (FH) and factor I (FI), to prevent nonessential activation. …”
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Differential modulation of SARS-CoV-2 infection by complement factor H and properdin by Uday Kishore, Uday Kishore, Praveen M. Varghese, Chandan Kumar, Susan Idicula-Thomas, Martin Mayora Neto, Anthony G. Tsolaki, Pretty Ponnachan, Pretty Ponnachan, Khaled Masmoudi, Basel Al-Ramadi, Basel Al-Ramadi, Manu Vatish, Taruna Madan, Taruna Madan, Nigel Temperton, Nazar Beirag, Nazar Beirag

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Relationship of gene polymorphisms for complement components C3 and factor H and kidney allograft function by Marija Milinkovic, Vladimir Perovic, Stefan Maksimovic, Irena Vukovic, Milica Kravljaca, Voin Brkovic, Iman Assi Milosevic, Milan Radovic, Mirjana Lausevic

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Complement-Inhibiting Therapy of Atypical Haemolytic Uremic Syndrome in a Patient With Factor H Mutation by Irina N. Lupan, Alexander Yu. Pischalnikov, Hadizha M. Emirova, Ekaterina S. Stolyarevich, Alexander M. Volyansky, Larisa V. Glukhova

“…This article presents a clinical observation of a patient with aHUS who had an identified heterozygous factor H (CFH) mutation — c.3653G>A(p.Cys1218Tyr), and two heterozygous variants of polymorphism in the same gene — c.2016A>G; c.2808G>T. …”
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Factor H-related 2 levels dictate FHR dimer composition by Bert R. J. Veuskens, Mieke C. Brouwer, Gerard van Mierlo, Judy Geissler, Karin van Leeuwen, Maaike Derlagen, Nadia C. H. Keijzer, Mark Hoogenboezem, Taco W. Kuijpers, Richard B. Pouw

“…Dimerization is hypothesized to further increase their antagonistic function with complement regulator factor H (FH). So far, only FHR-1 homodimers and FHR-1/2 heterodimers could be quantified in a direct way. …”
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Target complement factor H / serum amyloid a signaling in trichloroethylene-induced immune kidney injury by Haibo Xie, Bo Liang, Jingyi Zhao, Chen You, Qirui Bai, Rui Li, Jian Chen, Pengcheng Zhou, Luolun Dong, Ruixuan Cheng, Jiaxiang Zhang, Qixing Zhu

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Complement factor h gene abnormalities in haemolytic uraemic syndrome: from point mutations to hybrid gene. by Marina Noris, Giuseppe Remuzzi

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Moss-derived human complement factor H modulates retinal immune response and attenuates retinal degeneration by Mandy Hector, Verena Behnke, Paulina Dabrowska-Schlepp, Andreas Busch, Andreas Schaaf, Thomas Langmann, Anne Wolf

Subjects: “…Complement factor H…”
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Structural analysis of the C-terminal region (modules 18-20) of complement regulator factor H (FH). by Hugh P Morgan, Haydyn D T Mertens, Mara Guariento, Christoph Q Schmidt, Dinesh C Soares, Dmitri I Svergun, Andrew P Herbert, Paul N Barlow, Jonathan P Hannan

“…Factor H (FH) is a soluble regulator of the human complement system affording protection to host tissues. …”
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Factor H-related 1 and heparan sulfate architecture contribute to complement dysregulation in C3 glomerulopathy by Amanda K. Slagle, Amanda K. Slagle, Nicolo Ghiringhelli Borsa, Kai Wang, Amanda O. Taylor, Nicole C. Meyer, Michael B. Jones, William D. Walls, Angela F. M. Nelson, Sarah M. Roberts, Mingyao Sun, Elena Goicoechea de Jorge, Santiago Rodriguez de Cordoba, Diana I. Jalal, Diana I. Jalal, Carla M. Nester, Yuzhou Zhang, Richard J. H. Smith, Richard J. H. Smith

Subjects: “…Factor H…”
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Complement factor H levels are decreased and correlated with serum C-reactive protein in late-onset Alzheimer's disease by Guo LU, Weihong LIU, Xinying HUANG, Yanxin ZHAO

Subjects: “…complement factor H…”
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Susceptibility to invasive meningococcal disease: polymorphism of complement system genes and Neisseria meningitidis factor H binding protein. by Declan T Bradley, Thomas W Bourke, Derek J Fairley, Raymond Borrow, Michael D Shields, Peter F Zipfel, Anne E Hughes

“…Polymorphism of Complement Factor H (CFH) is associated with altered risk of invasive meningococcal disease (IMD). …”
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Autoantibodies Against Factor B and Factor H Without Pathogenic Effects in a Patient with Immune Complex-Mediated Membranoproliferative Glomerulonephritis by Alexandra T. Matola, Dorottya Csuka, Ágnes Szilágyi, Michael Rudnicki, Zoltán Prohászka, Mihály Józsi, Barbara Uzonyi

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Hemolytic uremic syndrome with multiple organ involvement secondary to complement factor H p.Arg1215X mutation by Osman Yeşilbaş, Esra Şevketoğlu, Mey Talip Petmezci, Hasan Serdar Kıhtır, Meryem Benzer, Afig Berdeli

Subjects: “…complement factor H gene…”
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SARS-CoV-2 hijacks host CD55, CD59 and factor H to impair antibody-dependent complement-mediated lysis by Laura Gebetsberger, Zahra Malekshahi, Aron Teutsch, Gabor Tajti, Frédéric Fontaine, Nara Marella, André Mueller, Lena Prantl, Hannes Stockinger, Heribert Stoiber, Anna Ohradanova-Repic

“…Here, we demonstrate that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hijacks host cellular RCA members CD55 and CD59 and serum-derived Factor H (FH) to resist antibody-dependent complement-mediated lysis triggered by immunized human sera. …”
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Catastrophic antiphospholipid syndrome accompanied by complement regulatory gene mutation by Serim Pul, Betül Sözeri, Cemile Pehlivanoğlu, Deniz Filinte, Özde Nisa Türkkan, Mehtap Sak, Neslihan Çiçek, Serçin Güven, Ece Demirci Bodur, İbrahim Gökçe, Harika Alpay

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