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Complement Activation: An Emerging Player in the Pathogenesis of Cardiovascular Disease
Published 2012-01-01“…An increasing body of evidence supports a functional role for complement activation in the pathogenesis of CVD through pleiotropic effects on endothelial and haematopoietic cell function and haemostasis. …”
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ORGANIZATION OF INTERACTION AT IMPLEMENTATION OF SALE OF GOODS IN CRIMINAL AND EXECUTIVE SYSTEM
Published 2017-10-01“…Establishments of criminal and executive system regarding the ensuring protection of the rights, freedoms and legitimate interests condemned, accused, suspects and persons who are held in custody are urged to provide them with the necessary range of commodity stocks, food, things and necessities. …”
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Complement C3 inhibition reduces complement activation in clinical platelet concentrates but does not counteract platelet storage lesions
Published 2025-12-01“…While C3 inhibition effectively reduced complement activation in stored platelet concentrates, it did not mitigate platelet storage lesions.…”
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Zinc supplementation inhibits complement activation in age-related macular degeneration.
Published 2014-01-01“…Furthermore, we investigated the effect of zinc on complement activation in vitro. …”
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Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury
Published 2024-12-01“…Using human neutrophils, we showed that absence of C3 or C1q caused a reduction in the volume of necrotic debris that is phagocytosed, indicating that complement promotes effective debris uptake in mice and humans. …”
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Analysis of the use of the electronic document management system in federal executive authorities
Published 2021-09-01“…In this regard, many companies begin to review their activities and move away from paper document management to electronic…”
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Complement activation by the artificial surface of cardiopulmonary bypass is a persistent clinical problem
Published 2025-07-01“…Circuit exposure time was a predictor of only C3a concentration in multivariable generalized linear mixed-effects models. Despite modern biocompatibility technology, there is significant alternative complement activation during ex-vivo sanguineous CPB prime preparation. …”
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Ensuring food security as a field of activity of executive authorities
Published 2025-05-01“…The conceptual provisions of legal acts on the activities of federal executive authorities in the field of food security have been analyzed, and the main directions of their activities in this area have been identified. …”
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The stability of complement-mediated bactericidal activity in human serum against Salmonella.
Published 2012-01-01“…Up to three freeze-thaw cycles had no effect on the persistence of bactericidal activity and hemolytic complement assays confirmed no effect on complement function. …”
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Plasma and complement proteins are essential for the antimicrobial activity of canine platelet lysate
Published 2025-07-01“…Additionally, platelets possess antimicrobial properties, which can be influenced by their manufacturing process, platelet and leukocyte concentration, activation method, and the presence of plasma and complement. …”
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Luciferase complementation based-detection of G-protein-coupled receptor activity
Published 2018-07-01“…Protein complementation assays (PCA) are used as pharmacological tools, enabling a wide array of applications, ranging from studies of protein–protein interactions to second messenger effects. …”
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Effectiveness of school-based active breaks on classroom behavior, executive functions and physical fitness in children and adolescent: a systematic review
Published 2025-01-01“…However, the effects of active breaks on executive functions and physical fitness are unclear. …”
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Tocilizumab modulates the activity of the classical and alternative complement pathways in rheumatoid arthritis patients
Published 2025-01-01“…The decrease in the alternative pathway was significant at weeks 12 and 24, but not at week 52 of TCZ treatment. TCZ had no effect on the lectin cascade throughout the follow-up.ConclusionTCZ reduces the activity of the classical and alternative pathways of the complement system in RA patients regardless of the improvement in disease activity. …”
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The Effectiveness of Implementing the Independent Curriculum in Shaping an Innovative Generation in Indonesia
Published 2025-05-01“…This study aims to analyze the effectiveness of the implementation of the Independent Curriculum in shaping an innovative generation in Indonesia. …”
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Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause Release and Complement Activation in KRAS‐mutant Cancers
Published 2024-11-01“…Co‐targeting of CDK9 and KRAS/MAPK signaling pathways eliminates ERK‐MYC activation and prevents feedback activation mediated by receptor tyrosine kinases, leading to more effective control of KRAS‐mutant cancers and overcoming KRASi resistance. …”
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The risks arising at execution and the termination of legal relationship in the field of town-planning activity
Published 2020-01-01“…On the basis of the analysis of the acting federal and regional legislation, and also jurisprudence the risks arising at execution and the termination oflegal relationship in the field of town-planning activity are classified by cases of town-planning disputes and also problems of protection of the rights of citizens are shown, at implementation of so-called dot building.…”
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Cost-effectiveness of support for health professionals to implement physical activity promotion: a protocol for within-trial and modelled economic evaluations of the PROMOTE-PA effectiveness-implementation hybrid trial
Published 2025-04-01“…Promotion of Physical Activity by Health Professionals is a hybrid type 1 effectiveness-implementation cluster randomised trial designed to evaluate the impact of physical activity promotion by health professionals (n=30 clusters) on physical activity participation in their patients (n=720). …”
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