Inhibition of complement activation, myeloperoxidase, NET formation and oxidant activity by PIC1 peptide variants. by Pamela S Hair, Adrianne I Enos, Neel K Krishna, Kenji M Cunnion

“…<h4>Background</h4>A product of rational molecular design, PA-dPEG24 is the lead derivative of the PIC1 family of peptides with multiple functional abilities including classical complement pathway inhibition, myeloperoxidase inhibition, NET inhibition and antioxidant activity. …”
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Plasmin Cascade Mediates Thrombotic Events in SARS-CoV-2 Infection via Complement and Platelet-Activating Systems by Kavitha Mukund, Kalai Mathee, Shankar Subramaniam

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Activity-based contracting for optimization of the mass distribution of insecticide-treated nets in the Democratic Republic of Congo: pilot implementation in Kwilu province by Losimba Likwela J, Kalonji Ntumba A, Ndolerire Isingoma C, Mukomena Sompwe E, Tsasa Mbuku E, Mbuse Angembo F, Mbuyu Lukunde E, Lukanu Ngwala P., N.’siala Kumbi A, Panou I, Masoswa L, Mashako P, Kanku‑Ka‑Lukusa P, Kulimushi Ndahambara G, Luntadila Kiamenga M, Minuku Kinzonzi F, Ngoma Kintaudi L, Wierzynska A, Erskine M

“…An innovative activity-based contracting (ABC) approach has been implemented in Kwilu Province, Democratic Republic of Congo to optimize ITN mass distribution campaigns, with payments based on contractually defined programmatic outcomes for key campaign activities following independent verification of results. …”
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Implementation of MobileNet Architecture for Skin Cancer Disease Classification by Haniifa Aliila Faudyta, Jesica Trivena Sinaga, Egia Rosi Subhiyakto

“…As the number of occurrences of skin cancer increases year, it becomes more and more crucial to identify the disease accurately and effectively. This study aims to implement and evaluate the MobileNet architecture for classifying nine types of skin lesions using the ISIC 2020 dataset and to compare MobileNet's performance with other CNN architectures, such as VGG-16 and LeNet, in terms of accuracy and computational efficiency. …”
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NRICM101 in combatting COVID-19 induced brain fog: Neuroprotective effects and neurovascular integrity preservation in hACE2 mice by Cher-Chia Chang, Yea-Hwey Wang, Jiin-Cherng Yen, Chia-Ching Liaw, Keng-Chang Tsai, Wen-Chi Wei, Wen-Fei Chiou, Chun-Tang Chiou, Kuo-Tong Liou, Yuh-Chiang Shen, Yi-Chang Su

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FUNCTIONAL ACTIVITY OF COMPLEMENT CLASSIC WAY ACTIVATION COMPONENTS AND ART1CULAS DAMAGE IN RHEUMATOID ARTRITIS by D. L. Goryachev, T. V. Lebedeva

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Complement Activation in Association with Markers of Neutrophil Extracellular Traps and Acute Myocardial Infarction in Stable Coronary Artery Disease by Karsten E. Kluge, Miriam S. Langseth, Trine B. Opstad, Alf Å. Pettersen, Harald Arnesen, Theis Tønnessen, Ingebjørg Seljeflot, Ragnhild Helseth

“…Complement activation and neutrophil extracellular traps (NETs) have both been suggested to drive atherosclerotic plaque progression. …”
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Evaluation of COVID-19 vaccine implementation in a large safety net health system by Jennifer C. Chen, Jennifer C. Chen, Griselda Gutierrez, Griselda Gutierrez, Rachel Kamran, Jill Terry, Jill Terry, Armenui Telliyan, Armenui Telliyan, Camilo Zaks, Savanna L. Carson, Arleen Brown, Karen Kim, Karen Kim

“…ObjectivesTo evaluate rapid COVID-19 vaccine clinic implementation from January-April 2021 in the Los Angeles County Department of Health Services (LACDHS), the second-largest US safety net health system. …”
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Provider readiness and implementation barriers for lung cancer screening in a safety-net system by Maria C. Mejia, Yu-Heng Hilary Ma, Lisa M. Lowenstein, Kiara K. Spooner, Gabrielle Duhon, Elisa E. Douglas, Viola Leal, Robert J. Volk

“…Objective: Lung cancer screening (LCS) with low-dose computed tomography is a critical preventive strategy, yet implementation remains complex, particularly in safety-net settings. …”
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Activated Immune and Complement C3 Are Potential Contributors in MASH via Stimulating Neutrophil Extracellular Traps by Ao Liu, Xiaoling Deng, Shuhui Hou, Yuwen Xi, Keshu Xu

“…Immunity systems were activated in MASH and elevated IgG activated C3 to stimulate the production of NETs, thus exacerbating MASH.…”
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RMIS-Net: a fast medical image segmentation network based on multilayer perceptron by Binbin Zhang, Guoliang Xu, Yiying Xing, Nanjie Li, Deguang Li

“…The network incorporates layer normalization and dropout regularization to ensure training stability, complemented by Gaussian error linear unit (GELU) activation functions for improved non-linear modeling. …”
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A wavelet CNN with appropriate feed-allocation and PSO optimized activations for diabetic retinopathy grading by Chandrasekaran Raja, Santhosh Krishna B V, Balaji Loganathan, Sanjay Kumar Suman, L. Bhagyalakshmi, Mubarak Alrashoud, Jayant Giri, T. Sathish

“…The authors re-architecture 3 different CNNs published in the Retinal Image analysis field, with spatial and wavelet inputs with optimized activations. The highest accuracy of 96% is attained with the AlexNet re-architecture, with 35,126 fundus images secured from the Kaggle dataset. …”
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TAX ALTERNATIVES TO IMPLEMENT THE TAX CAPACITY OF INTERNET ACTIVITY IN UKRAINE by I. O. Tsymbaliuk, T. O. Shmatkovska, Y. V. Shulyk

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Implementation of Explainable Ai in Deep Learning Methods for Multiclass Classification of Plant Diseases in Mango Leaves by Menaka Radhakrishnan

“…Further, Grad-CAM (Gradient-weighted Class Activation Mapping) has been implemented to highlight important regions in the leaf images which improves visualization. …”
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Payment Scheduling Problem with Multiple Modes for Activities to Maximize the Net Present Value of a Project by Somayeh Ghasedi, Behrouz Afshar-Nadjafi

“…In this paper, the multimode payment scheduling project is studied, which aims to maximize the net present value (NPV) of a project by deciding on payments and the start times of its activities. …”
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Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia by Alex Ramos, Alex Ramos, Lina Youssef, Lina Youssef, Patricia Molina, Sergi Torramadé-Moix, Julia Martinez-Sanchez, Julia Martinez-Sanchez, Ana Belen Moreno-Castaño, Miquel Blasco, Miquel Blasco, Elena Guillén-Olmos, Blanca De Moner, Blanca De Moner, Blanca De Moner, Marc Pino, Marta Tortajada, Marta Camacho, Maria Borrell, Francesca Crovetto, Maria Jose Ramirez-Bajo, Pedro Ventura-Aguiar, Pedro Ventura-Aguiar, Elisenda Banon-Maneus, Jordi Rovira, Gines Escolar, Enric Carreras, Enric Carreras, Eduard Gratacos, Eduard Gratacos, Maribel Diaz-Ricart, Maribel Diaz-Ricart, Fatima Crispi, Fatima Crispi, Marta Palomo, Marta Palomo

“…Whereas EVs trigger a pro-oxidant and proinflammatory state, NETs potentiate the activation of the complement system, as already described in PE.…”
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High-Quality Text-to-Speech Implementation via Active Shallow Diffusion Mechanism by Junlin Deng, Ruihan Hou, Yan Deng, Yongqiu Long, Ning Wu

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Targeting mucosal immunity in malaria control: the underexplored role of IgA by Haruna Muwonge, Haruna Muwonge, Isaac Ssewanyana, Adoke Yeka, Pauline Byakika-Kibwika, Pauline Byakika-Kibwika

“…Evidence suggests that IgA can block parasite entry, activate complement, and modulate inflammation, although its protective efficacy has yet to be established. …”
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Experiences of general practice teams and their patients with clinical research—a mixed-methods process evaluation of the Bavarian Research Practice Network (BayFoNet) by Linda Sanftenberg, Anna-Lena Schnaidt, Stefanie Eck, Antonius Schneider, Eva Bucher, Peter Konstantin Kurotschka, Ildikó Gágyor, Merle Klanke, Stefanie Stark, Thomas Kühlein, Fabian Walter, Marco Roos, Tobias Dreischulte, Jochen Gensichen, for the BayFoNet study group

“…Therefore, the aim of this study was to evaluate the perspectives of the GP teams and their patients on the set up of BayFoNet during the implementation of the two pilot cluster-randomized trials to improve this collaboration on a sustainable basis. …”
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Physiotherapy in Parkinson’s Disease: Building ParkinsonNet in Czechia by Ota Gal, Martin Srp, Romana Konvalinkova, Martina Hoskovcova, Vaclav Capek, Jan Roth, Evzen Ruzicka

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