Mesenchymal Stem Cells after Polytrauma: Actor and Target by Markus Huber-Lang, Rebecca Wiegner, Lorenz Lampl, Rolf E. Brenner

“…This in turn leads to complement opsonization, lysis, clearance by macrophages, and reduced migratory and regenerative abilities which culminate in impaired tissue repair. …”
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Soft law for unintentional empathy: addressing the governance gap in emotion-recognition AI technologies by Andrew McStay, Vian Bakir

“…This paper asks: should international soft law mechanisms, such as ethical standards, complement hard law in addressing governance gaps in emotion recognition and empathy-emulating AI technologies? …”
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Pathogenesis and detection methods of anti-acetylcholine receptor antibodies in myasthenia gravis by Shigeaki Suzuki

“…The main pathogenic mechanism of MG is the activation of the complement system caused by the attack of anti-AChR antibodies. …”
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The Production of Supplementary Learning Materials of Arabic Grammatology Based on The Curriculum 2013 with Scientific Approach at The First State Islamic Senior Hight School Malan... by Abdurrahman Shobirin, Wildana Wargadinata, Nur Hasan

“…So, the book need supplementary learning materials to complete teaching complement. This research is development research use Borg and Gall model that it consist of 10 steps. …”
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Evolving Lattices for Analyzing Behavioral Dynamics of Characters in Literary Text by Eugene S Kitamura, Yukio-Pegio Gunji

“…The resulting lattice provides information such as complementarity (lattice complement existence rate) and distributivity (lattice complement possession rate). …”
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A Holistic Approach to the Measurement of Physical Function in Clinical Research by Jennifer C. Richards, Shelby L. Bachman, Krista Leonard-Corzo, Suvekshya Aryal, Jennifer M. Blankenship, Ieuan Clay, Kate Lyden

“…Lastly, we discuss how successful implementation of digital tools within clinical research requires patient input. …”
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Implementasi Kebijakan Pembebasan Biaya Kesehatan Dasar by Akadun Akadun

“…This study aims to analisys the role organization communication in implementing public policy of free-cost of basic health service. …”
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Anti-GD2 IgA kills tumors by neutrophils without antibody-associated pain in the preclinical treatment of high-risk neuroblastoma by Stefan Nierkens, Niels Eijkelkamp, Maaike Nederend, Jeanette Leusen, Mitchell Evers, Marjolein Stip, Kaylee Keller, Hanneke Willemen, Marco Jansen, Chilam Chan, Kevin Budding, Thomas Valerius, Friederike Meyer-Wentrup

“…This novel reformatted IgA is unable to activate the complement system but efficiently activates leukocytes through the FcαRI (CD89).Results IgA GD2 did not activate the complement system in vitro nor induced pain in mice. …”
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Bioimpedance analysis in determining body composition in women with systemic lupus erythematosus: a pilot study by L. V. Kondratyeva, T. A. Panafidina, T. V. Popkova, Yu. R. Varaeva, A. V. Starodubova

“…There is a direct correlation of visceral fat content and inflammatory markers (CRP, complement component C3) and an inverse correlation of those with the SLEDAI-2K.…”
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Transcriptomic Analysis of Non-Specific Immune Responses in the Rice Field Eel (<i>Monopterus albus</i>) Infected with <i>Pallisentis (Neosentis) celatus</i> by Qin Lei, Xiaoling Li, Hao Wu, Yiwen Wan, Yukun Xie, Jinwei Gao, Wenwen Suo, Ming Zeng, Lingli Liu, Dongsheng Ou, Zhonggui Xie, Rui Song

“…Fluorescein-labeled <i>C9</i> antibody assays confirmed reduced complement <i>C9</i> levels in the infected tissues. …”
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Dietary Malondialdehyde Impair Intestinal Health and Fillet Quality of Hybrid Grouper (<i>Epinephelus fuscoguttatus</i>♀ <i>× E. lanceolatus</i>♂) by Xuehan Wang, Jiongting Fan, Xiaohui Dong, Shuang Zhang, Qihui Yang, Shuyan Chi, Haitao Zhang, Junming Deng, Beiping Tan

“…Dietary inclusion of 4.43 mg/kg MDA significantly decreased serum complement 4 content and lysozyme activity, along with intestinal complement 3, complement 4, and immunoglobulin M contents. …”
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Neuroprotective role of sialic-acid-binding immunoglobulin-like lectin-11 in humanized transgenic mice by Tawfik Abou Assale, Negin Afrang, Jannis Wissfeld, German Cuevas-Rios, Christine Klaus, Bettina Linnartz-Gerlach, Harald Neumann

“…Brains of 24-month-old Siglec-11 tg mice also exhibited lower gene transcription of complement components 3, 4, and integrin alpha M (C3, C4, and Itgam), along with the complement C1q subcomponents a-c (C1qa, C1qb, and C1qc). …”
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Beneath the surface in autoimmune hemolytic anemia: pathogenetic networks, therapeutic advancements and open questions by Alessandro Costa, Alessandro Costa, Olga Mulas, Olga Mulas, Angela Maria Mereu, Mercede Schintu, Marianna Greco, Giovanni Caocci, Giovanni Caocci

“…Glucocorticoids remain the standard first-line therapy for warm AIHA; in contrast, CAD/CAS is increasingly managed with agents targeting B-cell function or complement activation, including rituximab and sutimlimab. …”
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Evaluation of the Stability of Performance of the Analytical Test Method Used for Determination of Anticomplementary Activity of Human Immunoglobulin Preparations by O. G. Kornilova, E. A. Khusnatdinova, E. S. Konovalova, R. A. Volkova

“…Materials and methods: anticomplementary activity was determined by the complement fixation test in accordance with the general monograph of the State Pharmacopoeia of the Russian Federation (14th ed.) …”
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Exosome‐Mediated Lectin Pathway and Resistin‐MIF‐AA Metabolism Axis Drive Immune Dysfunction in Immune Thrombocytopenia by Jin Li, Xiaoqian Wang, Yaoyao Chen, Xianlei Sun, Liyan Fu, Qingxuan Xin, Huilin Zhang, Bo Qin, Nannan Sun, Yingmei Li, Yan Xu, Hui Yang, Dawei Huo, Yong Dong, Shuya Wang, Mengyun Zhao, Quande Lin, Fang Wang, Baohong Yue, Yanxia Gao, Yong Jiang, Rongqun Guo

“…In this study, using flow cytometry (FCM), proteomics, and single‐cell RNA sequencing of samples from patients with ITP, it is shown that exosome‐mediated lectin complement pathway is involved in the pathogenesis of ITP, which triggers and enlarges the complement activation cascade without effective regulation because of downregulated CD55. …”
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Determinants of response to daratumumab in Epstein-Barr virus-positive natural killer and T-cell lymphoma by Jennifer Yang, Anand D Jeyasekharan, Joanne Lee, Wee Joo Chng, Tae-Hoon Chung, Nurulhuda Mustafa, Adina Huey Fang Nee, Jing Yuan Chooi, Sabrina Hui Min Toh, Viknesvaran Selvarajan, Shuangyi Fan, Siok Bian Ng, Michelle Poon, Esther Chan, Yen Lin Chee, Longen Zhou

“…Increasing the CD38:CIP ratio through sequential CIP knockdown, followed by CD38 upregulation via All-Trans Retinoic Acid treatment, potently augments complement-mediated lysis in cells previously resistant to daratumumab. …”
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Serum adipsin levels in rheumatic diseases: defining its role in disease activity and progression in rheumatoid arthritis and axial spondyloarthritis by Marta Novella-Navarro, Marta Novella-Navarro, Laura González-Sánchez, Laura González-Sánchez, Borja Hernández-Breijo, Rebeca Pérez De Diego, Pilar Sánchez-Corral, Margarita López-Trascasa, Margarita López-Trascasa, Maria-Eugenia Miranda-Carús, Maria-Eugenia Miranda-Carús, Alejandro Villalba, Alejandro Villalba, Alejandro Balsa, Alejandro Balsa, Eugenio De Miguel, Eugenio De Miguel, Chamaida Plasencia-Rodríguez, Chamaida Plasencia-Rodríguez, Fernando Corvillo

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Artificial Intelligence in Medical Education: A Practical Guide for Educators by Nivritti Gajanan Patil, Nga Lok Kou, Daniel T. Baptista‐Hon, Olivia Monteiro

“…Despite existing discussions on AI in education, there is a lack of practical guidance on how medical educators can effectively and responsibly implement AI tools in teaching. This perspective provides a practical guide for medical educators to effectively incorporate AI tools to complement their teaching strategies, generate student assessments and to adapt assignments suitable for the AI era. …”
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The influence of IS1301 in the capsule biosynthesis locus on meningococcal carriage and disease. by Elisabeth Kugelberg, Bridget Gollan, Christopher Farrance, Holly Bratcher, Jay Lucidarme, Ana Belén Ibarz-Pavón, Martin C J Maiden, Ray Borrow, Christoph M Tang

“…Previously we have shown that insertion of IS1301 in the sia/ctr intergenic region (IGR) of serogroup C Neisseria meningitidis (MenC) isolates from Spain confers increased resistance against complement-mediated killing. Here we investigate the significance of IS1301 in the same location in N. meningitidis isolates from the UK. …”
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Role of differential gene expression in the occurrence and development of diabetic nephropathy by Chen Li-ting, Yue Rui, Wang Xi-yue, Kong Fan-wu

“…Objective The pathogenesis of diabetic nephropathy is rather complex.It is an abnormal metabolic process involving multiple genes and multiple steps.Therefore it is necessary to search for genes playing a key role in the occurrence and development of diabetic kidney disease（DKD）.Methods Bioinformatic was utilized for selecting the relevant data of DKD.And R software was employed for conducting differential gene screening for locating the key genes affecting DKD.Results There were 133 differential genes screened in GSE30528,704 differential genes in GSE1009 and 134 differential genes in GSE30529.Moreover, these genes are generally involved in renal development, collagen trimer aggregation, complement and coagulation cascade and AGE-RAGE signaling.Conclusion The genes VEGFA,MAGI2 and NPHS1 involved in the differentiation of glomerular filtering cells affect the glomerular structural changes in DKD;Genes S100 A9,FCER1 G,C3 AR1,CXCL1,ITGB2,COL1 A2 and LUM involved in tubulointerstitial inflammatory cell activation and collagen formation affect tubulointerstitial fibrosis in DKD;COL4 A3 and its family genes of AGE-RAGE signaling pathway, as well as F2 R,F5,F3,C3 genes of complement and coagulation cascade reaction are involved in the development of DKD.…”
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