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Specific surface-modified iron oxide nanoparticles trigger complement-dependent innate and adaptive antileukaemia immunity
Published 2024-11-01“…Mechanistically, IONP-COOH indirectly binds to C3b after activating the complement alternative pathway, subsequently enhancing phagocytosis of macrophages and activating adaptive immunity mediated by complement corona. …”
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Complement-Mediated Hemolytic Uremic Syndrome Due to MCP/CD46 Mutation: A Case Report
Published 2025-01-01“…Thrombotic microangiopathy (TMA) is a severe condition characterized by microangiopathic hemolytic anemia, thrombocytopenia, and end-organ damage, often involving the kidneys. Complement-mediated hemolytic uremic syndrome (cHUS), a rare form of TMA, arises from dysregulated alternative complement pathway activation, frequently due to genetic mutations. …”
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The Study of Serum Complement C3, C4 and Immunoglobulin E IgE in Psoriasis Patients
Published 2015-12-01“…The present study was aimed to find out the role of humoral immunity in the pathogenesis of psoriasis. Complements C3, C4 and immunoglobulin IgE .The study included 55 Iraqi patients with psoriasis 30 (15 females ,15 males) were untreated with any drugs. …”
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Venom from Bothrops lanceolatus, a Snake Species Native to Martinique, Potently Activates the Complement System
Published 2018-01-01“…Here, we investigated the ability of B. lanceolatus venom to activate the Complement system (C) in order to improve the understanding of venom-induced local inflammation. …”
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Factor H-related 1 and heparan sulfate architecture contribute to complement dysregulation in C3 glomerulopathy
Published 2025-05-01Subjects: Get full text
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Leptospira interrogans endostatin-like outer membrane proteins bind host fibronectin, laminin and regulators of complement.
Published 2007-11-01“…Infectious leptospires are resistant to killing by their hosts' alternative pathway of complement-mediated killing, and interact with various host extracellular matrix (ECM) components. …”
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A Prospective Study on Complement Activation Distinguishes Focal Segmental Glomerulosclerosis from Minimal Change Disease
Published 2024-03-01Subjects: “…complement activation…”
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Classical Complement (CH 50 ) activity among children with some bacterial and parasitic infections in Sokoto, Nigeria
Published 2018-12-01Subjects: “…complement activity, children, elisa, microbial infection…”
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KLF4 overexpression protects against complement-mediated endothelial injury in transplant-associated thrombotic microangiopathy
Published 2025-08-01“…Although complement blockade benefits some patients, effective prophylactic and therapeutic strategies remain scarce. …”
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THE VERTEX DISTANCE COMPLEMENT SPECTRUM OF SUBDIVISION VERTEX JOIN AND SUBDIVISION EDGE JOIN OF TWO REGULAR GRAPHS
Published 2021-07-01Subjects: “…distance matrix, vertex distance complement spectrum, subdivision vertex join, subdivision edge join…”
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Estimation of Complement Components (C3 and C4) and hs-CRP Level in Kidney Failure Patients
Published 2019-12-01Subjects: “…complement;…”
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Bead arrays for antibody and complement profiling reveal joint contribution of antibody isotypes to C3 deposition.
Published 2014-01-01“…Here, we present a bead array-based assay for a multiplexed determination of antigen-specific antibody levels in parallel with their properties for complement activation. We measured the deposition of C3 fragments from serum samples to reflect the degree of complement activation via all three complement activation pathways. …”
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Context, mechanisms and community engagement in implementation strategies: a systematic review protocol of implementation strategies designed using implementation mapping
Published 2024-11-01“…Introduction Implementation Mapping (IM) has increasingly been used for the design and/or selection and tailoring implementation strategies to promote the effective translation of evidence-based interventions into practice. …”
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