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    Cost-effectiveness of support for health professionals to implement physical activity promotion: a protocol for within-trial and modelled economic evaluations of the PROMOTE-PA effectiveness-implementation hybrid trial by Kirsten Howard, Anne Tiedemann, Catherine Sherrington, Michael Noetel, Marina Pinheiro, Leanne Hassett, Sakina Chagpar, Belinda Wang, Georgina Clutterbuck, Jennifer N Baldwin, Daniel Cheung, Kate Purcell, Roslyn Savage

    Published 2025-04-01
    “…Promotion of Physical Activity by Health Professionals is a hybrid type 1 effectiveness-implementation cluster randomised trial designed to evaluate the impact of physical activity promotion by health professionals (n=30 clusters) on physical activity participation in their patients (n=720). …”
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    Reduced hemolytic complement activity in the classical pathway (CH50) is a risk factor for poor clinical outcomes of patients with infections: a retrospective analysis of health insurance claims in Japan by Hiroyuki Koami, Hiroyuki Koami, Yutaro Furukawa, Yuri Hirota, Akira Sasaki, Hirotaka Ogawa, Ayaka Matsuoka, Kota Shinada, Kento Nakayama, Ryota Sakurai, Sachiko Iwanaga, Takayuki Onohara, Shogo Narumi, Mayuko Koba, Hirotaka Mori, Hirotaka Mori, Yutaka Umemura, Yutaka Umemura, Kazuma Yamakawa, Kazuma Yamakawa, Kohji Okamoto, Kohji Okamoto, Yuichiro Sakamoto, Yuichiro Sakamoto

    Published 2025-06-01
    “…PurposeTo evaluate whether low CH50 (a comprehensive measure of hemolytic activity of the classical complement pathway) is associated with infection-related coagulopathy, organ dysfunction, and poor clinical outcomes.MethodsThis was a retrospective study using Japanese health insurance claim data (2014-2023). …”
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