The role of complement in the immunopathogenesis of acetylcholine receptor antibody-positive generalized myasthenia gravis: bystander or key player? by Iliana Michailidou, Anastasia Patsiarika, Evangelia Kesidou, Marina Kleopatra Boziki, Marina Kleopatra Boziki, Dimitrios Parisis, Christos Bakirtzis, Elisabeth Chroni, Nikolaos Grigoriadis, Nikolaos Grigoriadis

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WCN24-550 SINGLE DOSE OF IPTACOPAN TREATMENT RAPIDLY DESCREASES PLASMA COMPLEMENT Bb LEVELS by Robert Schmouder, Guido Junge, Julie Milojevic, Prasanna Kumar Nidamarthy, Kenneth Kulmatycki

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Systematic Review of the Link Between Oxford MEST-C Classification and Complement Activation in IgA Nephropathy by Gabriel Ștefan, Eric Alamartine, Christophe Mariat, Nicolas Maillard

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Influence of Cow Dung Extract Complemented with Nutrient Solution on the Growth Performance of Lettuce (Lactuca sativa L) by Abu Raihan, Md. Jahedur Rahman, Chand Sultana Chandni, Sabina Yasmin, Md. Shahajahan Ali, M. Mokbul Hossain

“…Limited studies have focused on plant growth performance using organic-based solutions complemented with mineral elements in a hydroponic system. …”
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Influenza-specific antibody-mediated and complement-dependent cellular cytotoxicity-inducing antibodies in vaccinated and infected pigs by Mithilesh Singh, Gabriela Mansano do Nascimento, Sankar Renu, Dina Bugybayeva, Olaitan C. Shekoni, Raksha Suresh, Jennifer Schrock, Sara Dolatyabi, Diego G. Diel, Prosper N. Boyaka, Gourapura J. Renukaradhya

“…In addition to neutralizing activity, antibodies can contribute to protection against viral infections through antibody-dependent cellular cytotoxicity (ADCC) and antibody-mediated complement-dependent cell cytotoxicity (CDC) mediated via Fcy receptors. …”
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Moss-derived human complement factor H modulates retinal immune response and attenuates retinal degeneration by Mandy Hector, Verena Behnke, Paulina Dabrowska-Schlepp, Andreas Busch, Andreas Schaaf, Thomas Langmann, Anne Wolf

Subjects: “…Complement factor H…”
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Complementing muscle regeneration—fibro-adipogenic progenitor and macrophage-mediated repair of elderly human skeletal muscle by Jonas Brorson, Lin Lin, Jakob Wang, Amanda Bæk, Tine Borum Billeskov, Frederik Forsberg Thybo, Jesper Just, János Haskó, Christen Ravn, Rehne L. Hansen, Mats Bue, Jens Otto Lunde Jørgensen, Yonglun Luo, Niels Jessen, Jean Farup

“…Spatial correlation analysis unveils FAPs and monocytes/macrophages co-localization and intercellular communication, mediated by complement factor C3. Immunostaining confirms C3 expression in FAPs and FAP secretion of C3, suggesting a role in phagocytosis of necrotic muscle cells. …”
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Plasma complement proteins as biomarkers and therapeutic targets in chronic kidney disease: a Mendelian randomization analysis by Yu-Peng Xu, Zheng-Qi Song, Ming-Li Chen, Yang-Li Fang, Hui-Di Zhang

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Correction: Complement activity and autophagy are dysregulated in the lungs of patients with nonresolvable COVID‑19 requiring lung transplantation by Pooja Shivshankar, Stacey L. Mueller‑Ortiz, Aleksey Y. Domozhirov, Weizhen Bi, Scott D. Collum, Marie-Francoise Doursout, Manish Patel, Isabella N. LeFebvre, Bindu Akkanti, Simon Yau, Howard J. Huang, Rahat Hussain, Harry Karmouty-Quintana

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Isolation and Characterization of a New Peroxisome Deficient CHO Mutant Cell Belonging to Complementation Group 12 by K. Ghaedi

“…By this method, we have isolated one CHO cell mutant, ZPEG403, which was found to belong to complementation group G (CG-G). Expression of the human peroxin, Pex3p cDNA encoding a 373-amino-acid peroxisomal membrane protein morphologically and biochemically restored peroxisome biogenesis, including peroxisomal membrane assembly, in ZPEG403 cells. …”
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The predictive value of NLR, SII, and complement 3 in treatment response for systemic lupus erythematosus with immune thrombocytopenia by Ziqiang Zheng, Ziqiang Zheng, Jiali Liu, Taoyuan He, Taoyuan He, Chang Liu

“…The median SII values were 145.7 (43.7-238.7) for the CR group, 57.2 (20.5-90.2) for the PR group, and 117.8 (80.7-238.6) for the NR group. Additionally, complement 3 levels were significantly lower in the CR group compared to the PR and NR groups (P=0.010). …”
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Assessing Patients with Chronic Pain Using the Basic Personality Inventory as a Complement to the Multidimensional Pain Inventory by Howard J Burton, Stephen A Kline, Robin Hargadon, Barry S Cooper, Roger D Shick, May C Ong-Lam

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FUNCTIONAL ACTIVITY OF COMPLEMENT CLASSIC WAY ACTIVATION COMPONENTS AND ART1CULAS DAMAGE IN RHEUMATOID ARTRITIS by D. L. Goryachev, T. V. Lebedeva

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Structural analysis of the C-terminal region (modules 18-20) of complement regulator factor H (FH). by Hugh P Morgan, Haydyn D T Mertens, Mara Guariento, Christoph Q Schmidt, Dinesh C Soares, Dmitri I Svergun, Andrew P Herbert, Paul N Barlow, Jonathan P Hannan

“…Factor H (FH) is a soluble regulator of the human complement system affording protection to host tissues. …”
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Visualizing interactions along the Escherichia coli twin-arginine translocation pathway using protein fragment complementation. by Jan S Kostecki, Haiming Li, Raymond J Turner, Matthew P DeLisa

“…To visualize these interactions, we have adapted bimolecular fluorescence complementation (BiFC) to detect protein-protein interactions along the Tat pathway of living cells. …”
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The specific contributions of factor H and factor I in controlling fluid phase activation of the alternative complement pathway by Nancy A. Turner, Joel L. Moake

“…Abstract The immediate defense provided by the alternative complement pathway (AP) is under constant control by fluid phase regulators, factor H (FH) and factor I (FI), to prevent nonessential activation. …”
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Successful targeting of the alternative complement cascade with iptacopan for the treatment of IgA nephropathy: a case report by Leonore Ingold, Michael Dickenmann, Thomas Menter, Helmut Hopfer, Patricia Hirt-Minkowski

“…Iptacopan is an oral inhibitor of complement factor B that effectively blocks the alternative complement pathway. …”
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WCN24-2270 COMPLEMENT SYSTEM IS OVERACTIVATED IN PATIENTS WITH IGA NEPHROPATHY AFTER COVID-19 INFECTION by Hong Cheng, Wei-yi Guo, Guo-qin Wang, Ling-qiang Kong, Li-jun Sun, Xiao-yi Xu, Wen-rong Cheng, Hongrui Dong

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Genotypic and phenotypic diversity of Lactobacillus rhamnosus clinical isolates, their comparison with strain GG and their recognition by complement system. by Eija Nissilä, François P Douillard, Jarmo Ritari, Lars Paulin, Hanna M Järvinen, Pia Rasinkangas, Karita Haapasalo, Seppo Meri, Hanna Jarva, Willem M de Vos

“…The capacity of the L. rhamnosus strains to activate serum complement was studied using immunological assays for complement factor C3a and the terminal pathway complement complex (TCC). …”
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Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective by Didar Murad, Rehan Zafar Paracha, Maryum Nisar

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