Clinical characteristics and genetic profile of complement system in renal thrombotic microangiopathy in patients with severe forms of arterial hypertension by Mariam I. Akaeva, Natalia L. Kozlovskaya, Larisa A. Bobrova, Olga A. Vorobyeva, Ekaterina S. Stoliarevich, Petr A. Shatalov, Tatiana V. Smirnova, Anastasiia O. Anan'eva

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Characterization of the bispecific VHH antibody tarperprumig (ALXN1820) specific for properdin and designed for low-volume administration by Paul Tamburini, Dennis Vestergaard Pedersen, Denise Devore, Josh Cone, Rekha Patel, Todd Hunter, Fang Sun, Gregers Rom Andersen, Jeffrey Hunter

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SARS-CoV-2 hijacks host CD55, CD59 and factor H to impair antibody-dependent complement-mediated lysis by Laura Gebetsberger, Zahra Malekshahi, Aron Teutsch, Gabor Tajti, Frédéric Fontaine, Nara Marella, André Mueller, Lena Prantl, Hannes Stockinger, Heribert Stoiber, Anna Ohradanova-Repic

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THSD7A-associated membranous nephropathy involves both complement-mediated and autonomous podocyte injury by Jing Liu, Deepak Malhotra, Yan Ge, William Gunning, Lance Dworkin, Rujun Gong

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Correlation between serum level of complement C3 and abdominal aortic calcification in maintenance hemodialysis patients by Zhao Xin, Bi Chun-sheng

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Study the Serum Complement C3, C4 and Some Hematology Parameters in COVID-19 Disease by Mushtaq Karim Mash Abbas, Ibrahim Hadi Muhammed

“…All samples (from infected patients and healthy patients) were already identified by using Reverse Transcriptase Polymerase Chain Reaction (RT-PCR). Complement C3, C4 and white blood cells, lymphocytes and platelets were determined for all samples. …”
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Complement C4 exacerbates astrocyte-mediated neuroinflammation and promotes α-synuclein pathology in Parkinson’s disease by Wenkai Zou, Liang Kou, Yiming Wang, Zongjie Jin, Nian Xiong, Tao Wang, Yun Xia

“…Abstract Complement C4, implicated in neuroinflammation and synaptic dysfunction, plays a poorly defined role in Parkinson’s disease (PD). …”
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Effectiveness of Iptacopan Versus C5 Inhibitors in Complement Inhibitor‐Naive Patients With Paroxysmal Nocturnal Haemoglobinuria by Matthew Holt, Richard J. Kelly, Jilles M. Fermont, Soudeh Ansari, Marion Dahlke, Isabelle Brindel, Lynda Maafa, Flore Sicre deFontbrune, Régis Peffault deLatour

“…The single‐arm phase 3 APPOINT‐PNH trial (NCT04820530) investigating iptacopan monotherapy in complement inhibitor‐naive patients demonstrated significant haemoglobin concentration improvements. …”
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Target complement factor H / serum amyloid a signaling in trichloroethylene-induced immune kidney injury by Haibo Xie, Bo Liang, Jingyi Zhao, Chen You, Qirui Bai, Rui Li, Jian Chen, Pengcheng Zhou, Luolun Dong, Ruixuan Cheng, Jiaxiang Zhang, Qixing Zhu

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Complement factor h gene abnormalities in haemolytic uraemic syndrome: from point mutations to hybrid gene. by Marina Noris, Giuseppe Remuzzi

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Participatory science to complement professional data: Towards conservation of declining native freshwater fish, the crucian carp by Kiran Thomas, Lukáš Kalous, Marek Brabec, Petr Velenský, Milan Gottwald, Daniel Bartoň, Sandip Tapkir, Yevdokiia Stepanyshyna, Zuzana Šmejkalová, Marek Šmejkal

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Gut microbial dysbiosis activates the classical complement pathway in a short-term morphine treatment model by Nicolas Vitari, Richa Jalodia, Junyi Tao, Udhghatri Kolli, Salma Singh, Lily V. Rodriguez, Umakant Sharma, Sabita Roy

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An RNase H‐Like gene complements resistance to Bean common mosaic necrosis virus in Phaseolus vulgaris by Alvaro Soler‐Garzón, Phillip N. Miklas

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Evolving understanding of Guillain-Barré syndrome pathophysiology and the central role of the classical complement pathway in axonal injury by Kenneth C. Gorson

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Activated Immune and Complement C3 Are Potential Contributors in MASH via Stimulating Neutrophil Extracellular Traps by Ao Liu, Xiaoling Deng, Shuhui Hou, Yuwen Xi, Keshu Xu

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Contribution of Neurons and Glial Cells to Complement-Mediated Synapse Removal during Development, Aging and in Alzheimer’s Disease by Celia Luchena, Jone Zuazo-Ibarra, Elena Alberdi, Carlos Matute, Estibaliz Capetillo-Zarate

“…Microglial cells are involved in synapse pruning during development via the complement pathway. Moreover, recent evidence points towards a key role played by glial cells in synapse loss during AD. …”
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Differential dependencies of monocytes and neutrophils on dectin-1, dectin-2 and complement for the recognition of fungal particles in inflammation. by Jacqueline U McDonald, Marcela Rosas, Gordon D Brown, Simon A Jones, Philip R Taylor

“…We have re-investigated the role of the complement system and the non-opsonic pattern recognition receptors dectin-1 and dectin-2 in the recognition of fungal particles by inflammatory neutrophils, monocytes and macrophages. …”
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The role of complement C1q in atrial fibrillation: a marker for disease progression and surgical outcomes by Yuefeng Ju, MaoJing Wang, Yang Ji, Zhihui Wang, Wenzhuo Wang, Feiyue Liu, Qing Zhao

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Levodopa / opicapone as a complement to STN-DBS in clinical practice. A retrospective single-centre analysis. by Moritz A. Loeffler, Philipp Klocke, Idil Cebi, Alireza Gharabaghi, Daniel Weiss

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Increased Autoreactivity of the Complement-Activating Molecule Mannan-Binding Lectin in a Type 1 Diabetes Model by Jakob Appel Østergaard, Marieta Milkova Ruseva, Talat Habib Malik, Ingeborg Torp Hoffmann-Petersen, Matthew Caleb Pickering, Steffen Thiel, Troels Krarup Hansen

“…Identification of new drug targets is therefore of paramount importance. The complement system is emerging as a potential new target. …”
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