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    A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion. by Quynh Huong Nguyen, Chun Heng Royce Lai, Michael J Norris, Dixon Ng, Megha Shah, Christine Chieh-Lin Lai, David E Isenman, Trevor F Moraes

    Published 2025-05-01
    “…This is the first time that a bacterial protein has been shown to directly activate FI independent of complement cofactors and target all arms of the complement cascade.…”
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  3. 283

    In trans complementation of lethal factor reveal roles in colonization and dissemination in a murine mouse model. by David E Lowe, Jason Ya, Ian J Glomski

    Published 2014-01-01
    “…Decreases of the LF producing strains to 10% or 0.3% of the population led to increased host survival and decreased trans complementation of the LF mutants. A library with 10% LF producing clones could replicate and disseminate, but fewer clones disseminated and the mutant clones were less competitive than wild type. …”
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    Using Virtual Reality to Complement Traditional Wheelchair Skills Training Methods: A Literature Review by Chantal Zorzi, Alexandra Covaci, Gianluca Marcelli

    Published 2024-12-01
    “…However, the effectiveness of VR in complementing real-life training remains underexplored. …”
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  7. 287

    Multi-functional mechanisms of immune evasion by the streptococcal complement inhibitor C5a peptidase. by Nicola N Lynskey, Mark Reglinski, Damien Calay, Matthew K Siggins, Justin C Mason, Marina Botto, Shiranee Sriskandan

    Published 2017-08-01
    “…The complement cascade is crucial for clearance and control of invading pathogens, and as such is a key target for pathogen mediated host modulation. …”
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    Entrepreneurial opportunity decisions under uncertainty: Recognizing the complementing role of personality traits and cognitive skills by Emmanuel Kwasi Mensah, Lawrence Adu Asamoah, Vahid Jafari-Sadeghi

    Published 2021-01-01
    “…However, no integrated approach is offered in the literature to study how cognitive skills and personality traits complement each other.…”
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    Article
  11. 291

    BBK32 attenuates antibody-dependent complement-mediated killing of infectious Borreliella burgdorferi isolates. by Alexandra D Powell-Pierce, Charles E Booth, Payton G Smith, Brittany L Shapiro, Shannon S Allen, Brandon L Garcia, Jon T Skare

    Published 2025-07-01
    “…Borreliella burgdorferi, the causative agent of Lyme disease, has evolved unique complement evasion proteins that promote its ability to establish and maintain infection in mammalian hosts. …”
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  12. 292

    Prediction of activity of low-molecular inhibitors of the classic complement pathway using computational screening approach by D. M. Karlinsky, A. P. Kaplun, M. E. Popov

    Published 2009-06-01
    “…Using the molecular docking we estimated the free energy of binding of low-molecular ligands with the first component of complement protein C1q. The theoretically predicted values of IC50 allow selecting ligands with the highest inhibitory potential for further in vitro experiments…”
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    A role for LHC1 in higher order structure and complement binding of the Cryptococcus neoformans capsule. by Yoon-Dong Park, Soowan Shin, John Panepinto, Jeanie Ramos, Jin Qiu, Susana Frases, Patricia Albuquerque, Radames J B Cordero, Nannan Zhang, Uwe Himmelreich, David Beenhouwer, John E Bennett, Arturo Casadevall, Peter R Williamson

    Published 2014-05-01
    “…These changes in the capsular structure resulted in LHC1-dependent alterations of antibody binding patterns, reductions in human and mouse complement binding and phagocytosis by the macrophage-like cell line J774, as well as increased virulence in mice. …”
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    Clinical features of patients with homozygous complement C4A or C4B deficiency. by Inka Liesmaa, Riitta Paakkanen, Asko Järvinen, Ville Valtonen, Marja-Liisa Lokki

    Published 2018-01-01
    “…<h4>Introduction</h4>Homozygous deficiencies of complement C4A or C4B are detected in 1-10% of populations. …”
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