Urine complement analysis implies complement activation is involved in membranous nephropathy by Yingxue Xu, Yingxue Xu, Yi Li, Yong Zhang, Guisen Li, Guisen Li

“…BackgroundThe onset and progression of membranous nephropathy (MN) have been associated with complement activation, yet the overall characteristics of this activation in the kidneys remain unclear. …”
Get full text

Two complementing in vivo selection systems based on CCA-trimming exonucleases as a tool to monitor, select and evaluate enzymatic features of tRNA nucleotidyltransferases by Karolin Wellner, Josefine Gnauck, Dorian Bernier, Stephan H. Bernhart, Heike Betat, Mario Mörl

Get full text

Zinc supplementation inhibits complement activation in age-related macular degeneration. by Dzenita Smailhodzic, Freekje van Asten, Anna M Blom, Frida C Mohlin, Anneke I den Hollander, Johannes P H van de Ven, Ramon A C van Huet, Joannes M M Groenewoud, Yuan Tian, Tos T J M Berendschot, Yara T E Lechanteur, Sascha Fauser, Chris de Bruijn, Mohamed R Daha, Gert Jan van der Wilt, Carel B Hoyng, B Jeroen Klevering

“…Furthermore, we investigated the effect of zinc on complement activation in vitro. AMD patients with high levels of complement catabolism at baseline exhibited a steeper decline in serum complement activation (p<0.001) during the three month zinc supplementation period compared to patients with low complement levels. …”
Get full text

Association between circulatory complement activation and hypertensive renal damage: a case–control study by Zhongli Wang, Tingting Zhang, Xinyu Wang, Jianlong Zhai, Lili He, Sai Ma, Qingjuan Zuo, Guorui Zhang, Yifang Guo

“…Objective The aim of this study was to investigate the potential importance of complement system activation, with particular emphasis on the complement alternative pathway (AP), in the pathogenesis of hypertensive renal damage.Methods Serum complement C3, complement Factor H (CFH) and AP activation were assessed in 66 participants with established essential hypertension with renal damage (RD). …”
Get full text

SELECTION OF INVESTMENT PROJECTS IMPLEMENTATION OPTIONS by A. V. Kozlovsky, N. A. Moiseenko, O. E. Astafieva

Get full text

SELECTED ASPECTS OF THE IMPLEMENTATION OF ACTIVE MARKETING CAMPAIGN TO RAISE AWARENESS AND PROMOTE PUBLIC TRANSPORT SERVICES IN RURAL AREAS by Katarzyna NOSAL, Urszula DUDA

“…The article presents selected aspects of the implementation of the EU’s SmartMove project, which aims to promote feeder public transport systems in rural areas through the implementation of an active marketing campaign (AMC). …”
Get full text

Optimizing Telepractice Selection and Implementation for Persons with Aphasia by Elizabeth O. Tibus, Maryanne Weatherill, Amy D. Rodriguez

Get full text

Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause Release and Complement Activation in KRAS‐mutant Cancers by Yafang Wang, Lansong Xu, Lijun Ling, Mingyue Yao, Shangxuan Shi, Chengcheng Yu, Yingnian Li, Jie Shen, Hualiang Jiang, Chengying Xie

“…Mechanistically, CDK9 inhibition leads to compensatory activation of ERK‐MYC signaling, accompanied by the recovery of proto‐oncogenes, upregulation of immediate early genes (IEGs), stimulation of the complement C1r‐C3‐C3a cascade, and induction of tumor immunosuppression. …”
Get full text

Systematic Review of the Link Between Oxford MEST-C Classification and Complement Activation in IgA Nephropathy by Gabriel Ștefan, Eric Alamartine, Christophe Mariat, Nicolas Maillard

“…Methods: We adhered to the Preferred Reporting Items for Systematic Review and Meta-analysis guidelines and conducted a systematic review, utilizing databases like MEDLINE (PubMed), Embase, Scopus, and Cochrane from January 2016 (year of updated MEST-C classification) to January 2023. We specifically selected studies that employed established methods to evaluate complement activation and the MEST-C classification. …”
Get full text

Prediction of activity of low-molecular inhibitors of the classic complement pathway using computational screening approach by D. M. Karlinsky, A. P. Kaplun, M. E. Popov

Get full text

IMPLEMENTATION OF FUZZY SELECTION OF EQUIPMENT IN INFORMATION NETWORK DESIGN SYSTEM by Elena Nikolayevna Chuykova

“…The implementation of the equipment selection process in the information network design system on the basis of fuzzy criteria is considered. …”
Get full text

Complement and Coagulation Cascade Activation Regulates the Early Inflammatory Mechanism of Resistance of Suckling Lambs Against <i>Haemonchus contortus</i> by José Gabriel G. Lins, Alessandro F. T. Amarante

“…Our data identified potential markers for resistance trait selection in sheep, such as C3 (complement C3), F3 (tissue factor), F5 (coagulation factor V), CFB (complement factor B), and CFI (complement factor I). …”
Get full text

C3d-targeted complement inhibitors to correct complement dysregulation in aHUS patients by Valeria Guaschino, Donata Santarsiero, Sara Gastoldi, Joshua M. Thurman, V. Michael Holers, Shelia M. Violette, Fei Liu, Kelly C. Fahnoe, Chiara Guarinoni, Ariela Benigni, Giuseppe Remuzzi, Marina Noris, Sistiana Aiello

“…Atypical hemolytic uremic syndrome (aHUS) is a rare and severe thrombotic microangiopathy caused by genetic or acquired abnormalities leading to activation of the complement alternative pathway on cell surfaces. …”
Get full text

Development of an organizational and economic mechanism for the implementation of a product selection recommendation system by B.V. Kosogovskii

Get full text

Mapping autoantibody targets of full-length C-reactive protein in systemic lupus erythematosus: importance for neutrophil function and classical complement activation by Jesper Karlsson, Lina Wirestam, Hanna Duàn, Suhana Ahmad, Daniel Appelgren, Helena Enocsson, Jonas Wetterö, Christopher Sjöwall

“…Furthermore, we show that patients with anticardiolipin IgG and/or anti-β2GPI IgG antibodies have a higher number of positive CRP epitopes, and some CRP autoantibody-specificities associate with antiphospholipid antibodies, disease activity, and classical complement activation. In addition, one identified motif was selected, synthesized, and used for studying neutrophil function. …”
Get full text

Trust as a factor activating implementation abilities – from theory to practice of a flexible company by Nogalski Bogdan, Niewiadomski Przemysław

Get full text

Scene categorization by Hessian-regularized active perceptual feature selection by Junwu Zhou, Fuji Ren

“…A notable advantage of RDAL is the robustness to label noise, which is implemented by a carefully-designed sparse penalty term. …”
Get full text

Understanding the active ingredients, barriers, and facilitators to implement brief psychological interventions for substance misuse in Indian prisons: A qualitative study by Abhishek Ghosh, Renjith R. Pillai, Jatina Vij, Pallab K. Maulik, Blessy B. George, Debasish Basu

Get full text

The stability and modulation of if-then rules versus prospective planning in movement selection under dual-tasking conditions by S. E. M. Stoll, A. Wenzel, B. Hitzler, J. Randerath

Get full text

Active Multifunctional Frequency Selective Surfaces: An Insight Into Design, Behavior Analysis, and Applications by Harienthiran Maheswaran, Gulam Nabi Alsath Mohammed, Geethanjali Govindarajan, Malathi Kanagasabai, Kirubaveni Savarimuthu, Sandeep Kumar Palaniswamy, Sachin Kumar, Bhawna Goyal, Mousa I. Hussein

“…This investigation provides a critical review of the design methodologies for multifunctional active frequency selective surfaces (MAFSSs) and reconfigurable frequency selective surfaces (RFSSs), collectively referred to as active multifunctional frequency selective surfaces (AMFSSs). …”
Get full text