Candidiasis: Insights into Virulence Factors, Complement Evasion and Antifungal Drug Resistance by Nidaa Riaz Gaffar, Nisha Valand, Umakhanth Venkatraman Girija

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Clinical values of serum Gd-IgA1， complement factor H and complement regulatory proteins in IgA nephropathy by Zou Mei, Xue Hen, Lu Fang-cao, Zheng Guang-yi, Zhao Min

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The specific contributions of factor H and factor I in controlling fluid phase activation of the alternative complement pathway by Nancy A. Turner, Joel L. Moake

“…Abstract The immediate defense provided by the alternative complement pathway (AP) is under constant control by fluid phase regulators, factor H (FH) and factor I (FI), to prevent nonessential activation. …”
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A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion. by Quynh Huong Nguyen, Chun Heng Royce Lai, Michael J Norris, Dixon Ng, Megha Shah, Christine Chieh-Lin Lai, David E Isenman, Trevor F Moraes

“…Here, we report that PmSLP binds host complement factor I (FI) and facilitates cleavage of complement components C3b and C4b independently of any cofactors (e.g., FH, C4BP), thereby allowing the pathogen to evade host defence. …”
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Rheumatoid Factor, Complement, and Mixed Cryoglobulinemia by Peter D. Gorevic

“…Low serum level of complement component 4 (C4) that occurs in mixed cryoglobulinemia (MC) may be due to in vivo or ex vivo activation of complement by the classical pathway. …”
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Factor H-related 1 and heparan sulfate architecture contribute to complement dysregulation in C3 glomerulopathy by Amanda K. Slagle, Amanda K. Slagle, Nicolo Ghiringhelli Borsa, Kai Wang, Amanda O. Taylor, Nicole C. Meyer, Michael B. Jones, William D. Walls, Angela F. M. Nelson, Sarah M. Roberts, Mingyao Sun, Elena Goicoechea de Jorge, Santiago Rodriguez de Cordoba, Diana I. Jalal, Diana I. Jalal, Carla M. Nester, Yuzhou Zhang, Richard J. H. Smith, Richard J. H. Smith

Subjects: “…Factor H…”
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Complement factor H in molecular regulation of angiogenesis by Li Jiang, Wang Kaili, Starodubtseva Maria N., Nadyrov Eldar, Kapron Carolyn M., Hoh Josephine, Liu Ju

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Correlation of the Complement Decay Accelerating Factor, Tumour Necrosis Factors-alpha, and Interleukin-1 Beta with the Response to Rituximab in Rheumatoid Arthritis Patients by Haidar Mohammed Hussein, Ali Abdulhussein Kasim

“…The study aims to investigate the potential association of serum levels of the complement decay accelerating factor (DAF), as well as the pro-inflammatory cytokines, tumour necrosis factor-alpha (TNF-α) and interleukin-1 Beta (IL-1β); with response to RTX treatment in rheumatoid arthritis patients. …”
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Sequential Increase in Complement Factor I, iC3b, and Cells Expressing CD11b or CD14 in Cutaneous Vasculitis by Dina Rahkola, Tiina Lipitsä, Hanna Siiskonen, Anita Naukkarinen, Ilkka T. Harvima

“…Mast cells contribute to the pathogenesis of cutaneous vasculitis through complement C3 that is cleaved to C3b and then to iC3b by complement factor I. …”
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Factor-H-related protein 1 (FHR1), a promotor of para-inflammation in age-related macular degeneration by Andjela Sekulic, Sarah M. Herr, Kelly Mulfaul, Inga-Marie Pompös, Silvia Winkler, Carola Dietrich, Benedikt Obermayer, Robert F. Mullins, Thomas Conrad, Peter F. Zipfel, Florian Sennlaub, Christine Skerka, Olaf Strauß

“…Abstract Age-related macular degeneration (AMD), a multifactorial type of retinal degeneration represents the most common cause for blindness in elderly. Polymorphisms in complement factor-H increase, while absence of factor-H-related protein-1 (FHR1) decreases the AMD risk, currently explained by their opposing relationship. …”
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Regulation of anti-microbial autophagy by factors of the complement system by Christophe Viret, Aurore Rozières, Rémi Duclaux-Loras, Gilles Boschetti, Stéphane Nancey, Mathias Faure

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Complements and Allergic Asthma by Ching-Yuang Lin, Yi-Giien Tsai

“…Complement regulatory protein CD46 was shown to stimulate the development of IL-10 producing Tr1 cells. …”
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Factor H-related 2 levels dictate FHR dimer composition by Bert R. J. Veuskens, Mieke C. Brouwer, Gerard van Mierlo, Judy Geissler, Karin van Leeuwen, Maaike Derlagen, Nadia C. H. Keijzer, Mark Hoogenboezem, Taco W. Kuijpers, Richard B. Pouw

“…Dimerization is hypothesized to further increase their antagonistic function with complement regulator factor H (FH). So far, only FHR-1 homodimers and FHR-1/2 heterodimers could be quantified in a direct way. …”
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Complete recovery after complement factor I deficiency associated fulminant acute hemorrhagic leukoencephalitis: a case report by Fanni Szumutku, Léna Szabó, Zoltán Liptai, Edit Varga, Tímea Seszták, Péter Barsi, Ádám Goschler, Gábor Szarvas, Klára Horváth, Simon Péter Nagy, Zoltán Prohászka, Ágnes Szilágyi, Sarolta Dobner

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Apobec-1 complementation factor regulates cell migration and apoptosis through Dickkopf1 by acting on its 3′ untranslated region in MCF7 cells by Xin Yan, Qianyin Li, Dongsheng Ni, Yajun Xie, Qingling He, Qianya Wan, Yamin Liu, Zhongshi Lyu, Zhaomin Mao, Qin Zhou

“…A1CF (apobec-1 complementation factor) acts as a component of the apolipoprotein-B messenger RNA editing complex. …”
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Complete Complement Factor I (CFI) deficiency: a systematic review of forty-nine patients including three novel cases by Erta Rajabi, Mahsa Choroom Kheirabadi, Nasrin Alipour Olyaei, Anne Molitor, Mohadese Sadat Mousavi Khorshidi, Morteza Heidari, Arash Abbasi, Parastoo Rostami, Mohadese Mahdavi, Raphael Carapito, Mohammad Shahrooei, Seiamak Bahram, Nima Parvaneh

Subjects: “…Complement Factor I…”
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Glycoproteomics analysis of complement factor H and its complement-regulatory function during Streptococcus pneumoniae-associated hemolytic uremic syndrome by Laura M. Baas, Kioa L. Wijnsma, Fokje Zijlstra, Nicole C. A. J. van de Kar, Lieke ter Steeg, Antonia H. M. Bouts, Marloes A. H. M. Michels, Marloes A. H. M. Michels, Jeroen D. Langereis, Dirk Lefeber, Dirk Lefeber, Hans J. C. T. Wessels, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel

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Outer membrane protein OMP76 of Riemerella anatipestifer contributes to complement evasion and virulence by binding to duck complement factor vitronectin by Sen Li, Yanhua Wang, Rongkun Yang, Xiaotong Zhu, Hongying Bai, Xiaojian Deng, Jiao Bai, Yang Zhang, Yuncai Xiao, Zili Li, Zhengfei Liu, Zutao Zhou

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Complement component C1q initiates extrinsic coagulation via the receptor for the globular head of C1q in adventitial fibroblasts and vascular smooth muscle cells by Christopher T. Freda, Wei Yin, Berhane Ghebrehiwet, David A. Rubenstein

Subjects: “…complement…”
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Unique target binding by the C-terminal region of FHR1 provides a new perception of aHUS pathology by Luce Perie, Selina Stippa, Christoph Saffer, Christoph Saffer, Andrea Hartmann, Mathias Mörgelin, Svante L. H. Zipfel, Marc Thilo Figge, Marc Thilo Figge, Thorsten Wiech, Christine Skerka, Peter F. Zipfel, Peter F. Zipfel

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