Association of MSX1 gene polymorphisms and maxillary lateral incisor agenesis in Non-syndromic cleft lip and/or palate individuals by Dhanyashri Kamalakannan, Vignesh Kailasam, Sridevi Padmanaban, Solomon F.D. Paul, Gnanasambandan Ramanathan

“…Results: The three SNPs, rs12532, rs1042484 and rs11726039 of MSX1 gene exhibited polymorphism. rs12532 was associated with reduced risk of maxillary lateral incisor agenesis in NSCL/P subjects. rs1042484 had significant association with the NSCL/P without maxillary lateral incisor agenesis (full complement of teeth) subjects. rs11726039 showed significant association with NSCL/P with or without maxillary lateral incisor agenesis. …”
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Coronavirus disease 2019 (COVID-19) and immune-mediated inflammatory rheumatic diseases: at the crossroads of thromboinflammation and autoimmunity by E. L. Nasonov, T. V. Beketova, T. M. Reshetnyak, A. M. Lila, L. P. Ananieva, T. A. Lisitsyna, S. K. Soloviev

“…Delineating the autoimmune subtype of thromboinflammation, identification of genetic (i.e., genes encoding the complement system and others) and molecular-biologic biomarkers associated with higher occurrence of COVID-19-coagulopathy are the most relevant undertakings for the current practice. …”
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Manipulating adenovirus hexon hypervariable loops dictates immune neutralisation and coagulation factor X-dependent cell interaction in vitro and in vivo. by Jiangtao Ma, Margaret R Duffy, Lin Deng, Rachel S Dakin, Taco Uil, Jerome Custers, Sharon M Kelly, John H McVey, Stuart A Nicklin, Andrew H Baker

“…FX "coating" also protects the virus from host IgM and complement-mediated neutralisation. However, the contribution of FX in determining Ad liver transduction whilst simultaneously shielding the virus from immune attack remains unclear. …”
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Systematic mutagenesis of genes encoding predicted autotransported proteins of Burkholderia pseudomallei identifies factors mediating virulence in mice, net intracellular replicati... by Natalie R Lazar Adler, Mark P Stevens, Rachel E Dean, Richard J Saint, Depesh Pankhania, Joann L Prior, Timothy P Atkins, Bianca Kessler, Arnone Nithichanon, Ganjana Lertmemongkolchai, Edouard E Galyov

“…The bpaC mutant, which demonstrated attenuation for virulence and net intracellular replication, was sensitive to complement-mediated killing via the classical and/or lectin pathway. …”
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Tea Polyphenol Protects the Immune Barrier and Inhibits TLR2/NF-κB/MLCK Signal Activation to Prevent Inflammatory Injury in the Intestines of Common Carp (<i>Cyprinus carpio</i> L.... by Man Qian, Jie Yang, Yao Xue, Jiawei Wu, Ziyi Li, Jilong Luo, Bing Zhao, Xuejiao Gao

“…The qPCR and ELISA results showed that TP increased the levels of lysozyme (LZ), alkaline phosphatase (ALP), complement component 3 (C3), complement component 4 (C4), immunoglobulin T (IgT), immunoglobulin D (IgD), and immunoglobulin M (IgM) to activate intestinal immune ability. …”
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Exploring virulence and stress response in Entamoeba histolytica: insights from clinical strains by Yasuaki Yanagawa, Manu Sharma, Shinji Izumiyama, Upinder Singh

“…Functional assays demonstrated that the overexpression of these genes contributed to key virulence traits, including increased adhesion, complement resistance, and enhanced starch phagocytosis. …”
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Role of a New Walk Test in Pulmonary Arterial Hypertension: A Retrospective Cohort Study by Junhao Jin, Yao Mi, Aqian Wang, Bo Li, Kaiyu Jiang, Hai Zhu, Ting Liang, Hongling Su, Yunshan Cao

“…This study aimed to investigate the clinical utility of a new walk test, the 18‐meter walk test (18MWT), in patients with pulmonary arterial hypertension (PAH) as a complement to the 6MWT. In summary, a total of 117 patients with PAH from January 2018 to December 2022 were included. …”
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Effects of butyric acid and Protoxin probiotic in the feeding of Siberian sturgeon (Acipenser baerii) by Rasool Zare, Abdolmohammad Abedian Kenari

“…Materials and Methods: In this experiment, the effects of butyric acid and probiotic supplements (Protexin) and their combination on the growth performance, body composition, intestinal microbiota, and immune responses (lysozyme and complement) in juvenile Siberian sturgeon (Acipenser baerii) were investigated. …”
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Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules. by Steven Johnson, Lionel Tan, Stijn van der Veen, Joseph Caesar, Elena Goicoechea De Jorge, Rachel J Harding, Xilian Bai, Rachel M Exley, Philip N Ward, Nicola Ruivo, Kaushali Trivedi, Elspeth Cumber, Rhian Jones, Luke Newham, David Staunton, Rafael Ufret-Vincenty, Ray Borrow, Matthew C Pickering, Susan M Lea, Christoph M Tang

“…Factor H binding protein (fHbp) is a key antigen that elicits protective immunity against the meningococcus and recruits the host complement regulator, fH. As the high affinity interaction between fHbp and fH could impair immune responses, we sought to identify non-functional fHbps that could act as effective immunogens. …”
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Antifouling Surface‐Attached Hydrogel Nanocoatings Redefined: Green Solvent‐Based, Degradable, and High‐Performance Protection Against Foulants by Jenny Englert, Marc Palà, Jonas Quandt, Hannah Sieben, Oliver Grottke, Bernd Marx, Gerard Lligadas, Cesar Rodriguez‐Emmenegger

“…Despite significant advancements in antifouling coatings, like those based on zwitterionic monomers and hydroxyl‐functionalized (meth)acrylamides, limitations like decreased antifouling properties after functionalization and complement system activation hinder their application in blood. …”
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Host-adaptation of Francisella tularensis alters the bacterium's surface-carbohydrates to hinder effectors of innate and adaptive immunity. by Tiffany M Zarrella, Anju Singh, Constantine Bitsaktsis, Tabassum Rahman, Bikash Sahay, Paul J Feustel, Edmund J Gosselin, Timothy J Sellati, Karsten R O Hazlett

“…These capsules impede recognition of bacterial outer membrane constituents by antibody, complement, and Toll-Like Receptor 2. These changes in the host-pathogen interface have profound implications for pathogenesis and vaccine development.…”
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Genome editing for scalable production of alloantigen‐free lentiviral vectors for in vivo gene therapy by Michela Milani, Andrea Annoni, Sara Bartolaccini, Mauro Biffi, Fabio Russo, Tiziano Di Tomaso, Andrea Raimondi, Johannes Lengler, Michael C Holmes, Friedrich Scheiflinger, Angelo Lombardo, Alessio Cantore, Luigi Naldini

“…Altogether, these advances support scalable manufacturing of alloantigen‐free LV with higher purity and increased complement resistance that are better suited for in vivo gene therapy.…”
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An inactivated bivalent vaccine effectively protects Carassius auratus against Aeromonas caviae and Aeromonas veronii by Dongpeng Gao, Luotao Tao, Han Lu, Tonghao Suo, Jing Xiong, Xiaofeng Shan, Dongxing Zhang, Hao Dong, Ruoming Li

“…The serum levels of SOD, CAT, IgM, AKP, LZM, ACP, complement C3 and complement C4 were determined. Real-time fluorescence quantitative PCR was used to measure gene expression in the liver, spleen, kidney, and intestinal tissues. …”
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External Aspect of the Transport and Infrastructure Situation in ASEAN: New Opportunities and Risks for the EAEU Countries by Oleg Paramonov

“…However, the ASEAN states often face serious difficulties because of lack of modern railways as a necessary complement to the port infrastructure. Under current conditions, new opportunities are opening up for Russia both in the international market for transport services and in the implementation of infrastructure projects. …”
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Flexibilité adaptative et gestion du risque : étude de cas des inondations dans l’estuaire de la Gironde (France) by Nabil Touili, Jean-Paul Vanderlinden

“…Governance-based measures, previously perceived as a complement to structural measures, appear today prominent and, especially, are playing a dominant role in flood risk management. …”
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Réformes territoriales et modifications des rapports ville-montagne dans les Alpes-Maritimes by Lauranne Jacob

“…The creation of large coastal and alpine intermunicipal authorities signifies that links between urban and mountainous regions need to be addressed in order to ensure they complement each other.However, development policy for mountainous regions could result in a form of ‘disneyfication’ (Crettaz 1993) in mountainous regions.…”
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The Impact of Market Discipline on Banks’ Capital Adequacy: Evidence From an Emerging Economy by Ayesha Afzal

“…These findings have important implications for policymakers as market discipline could complement the role of regulators, which would eventually lower the cost of supervision. …”
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Multilateral trading system and regional economic integrations by Savić Biljana

“…WTO rules could and should be modified to ensure that regional agreements are designed and implemented so to complement the multilateral process and not to undermine it. …”
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Territorial Reforms and Changing Relationships Between Urban and Mountainous Regions in the Alpes-Maritimes département by Lauranne Jacob

“…The creation of large coastal and alpine intermunicipal authorities signifies that links between urban and mountainous regions need to be addressed in order to ensure they complement each other.However, development policy for mountainous regions could result in a form of ‘disneyfication’ (Crettaz 1993) in mountainous regions.…”
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Approche culturelle et écriture réflexive pour un public Lansad by Isabelle Salengros‑Iguenane

“…Our approach deals with both navigating the cultural difficulties incoming students to the École des Ponts ParisTech may experience, and designing and implementing a module using Internet. A central part of the module was journal writing by the students. …”
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