Calamities and Counterfactuals: A Historical View of Polarity Reversal by Debra Ziegeler

“…In the present study, the historical development of the two adverbs will be considered in investigating recent data from Late Modern English, in which a majority of counterfactual uses appear with a complement referring to undesirable events, sometimes expressed hyperbolically. …”
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An Approach to Neutrosophic Hyper Soft Rough Matrix and its Application by J. Boobalan, E. Mathivadhana

“…We discuss various operators on NHSRM such as addition, multiplication, scalar multiplication and complement. Additionally, we develop several properties, including associativity, distributivity and De Morgan’s laws, utilizing operators such as union, intersection, complement, arithmetic mean, weighted arithmetic mean, geometric mean, weighted geometric mean, harmonic mean and weighted harmonic mean. …”
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Some Results on Pure Submodules Relative to Submodule by Baghdad Science Journal

“…In this paper, the properties of the following concepts were studied: Pure essential submodules relative to submodule T of M (Simply T-pure essential),Pure closed submodules relative to submodule T of M (Simply T-pure closed) and relative pure complement submodule relative to submodule T of M (Simply T-pure complement) and T-purely extending. …”
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Age-Related Macular Degeneration in the Aspect of Chronic Low-Grade Inflammation (Pathophysiological ParaInflammation) by Małgorzata Nita, Andrzej Grzybowski, Francisco J. Ascaso, Valentín Huerva

“…The complement system, mainly alternative pathway, mediates chronic autologous pathophysiological parainflammation in dry and exudative AMD, especially in the Y402H gene polymorphism, which causes hypofunction/lack of the protective complement factor H (CFH) and facilitates chronic inflammation mediated by C-reactive protein (CRP). …”
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Macrophage Depletion Reduces Disease Pathology in Factor H-Dependent Immune Complex-Mediated Glomerulonephritis by Alexander Jacob, Michael Phelps, Shane Fraher, Marcos Lopez, Anthony Chang, Richard J. Quigg, Jessy J. Alexander

“…Complement factor H (FH) is a key regulator of the alternative pathway of complement, in man and mouse. …”
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Clinicopathological features of 60 cases of asymptomatic hematuria and/or proteinuria by GUO Chun-hua, LIN Chong-yun

“…Objective To investigate the clinicopathological features of asymptomatic hematuria and/or proteinuria.Methods The clinicopathological features were analyzed and correlated in 60 cases of asymptomatic hematuria and/or proteinuria.According to 24-h urine protein excretion >150 mg,60 cases were divided into simple hematuria group(n= 14,6 males and 8 females) and proteinuria groupCsimple proteinuria or proteinuria with hematuria)(n = 46,18 males and 28 females).The study population also was divided into IgA nephropathy group(n = 36,11 males and 25 females) and nonIgA nephropathy group(n=24,13 males and 11 females) by mesangial IgA deposition,and the statistical analysis was carried out respectively.Results The pathological features in proteinuria group were more severe and serum uric acid was higher in proteinuria group than in simple hematuria group[(305.5 ± 90.8) vs.(376.7 + 86.7) μmol/L,t=-2.27,P = 0.03],showed statistical significant difference,but there were no differences in serum creatinine,Cystatin C(CysC),serum IgA and complement C3.The creatinine levels of IgA nephropathy group was higher than Non-IgA nephropathy[(71.5 + 21.6) vs.(59.2 ± 14.8) μmol/L,t = 2.09,P = 0.04],but no differences in Cys C,serum uric acid,serum IgA Complement C3 and 24-hour urinary protein.Moreover,except 24-hour urinary protein,all the values were within the normal range of reference values.Conclusions Renal lesion can not be sensitively marked by clinical features,such as serum creatinine,Cys C,serum uric acid,serum IgA,Complement C3,24-hour urinary protein:renal biopsy is the criteria for diagnosis.So far,there is a lack of uniform scoring system to assess renal lesion.…”
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РОЛЬ ТРОМБОЦИТОВ В ПАТОГЕНЕЗЕ БАКТЕРИАЛЬНЫХ ИНФЕКЦИЙ by N. B. Serebryannaya, P. P. Yakutseni, N. N. Klimko

“…In the antibacterial immunity, platelets attract neutrophils, monocytes and activate the complement system. In this case, platelets act together with these cells and proteins, promoting the full disclosure of the microbicidal potential of phagocytes and complement. …”
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Methods to evaluate the performance of a multicomponent meningococcal serogroup B vaccine by Ray Borrow, Laura Tomasi Cont, Daniela Toneatto, Stefania Bambini, Shravani Bobde, Woo-Yun Sohn, Alessia Biolchi, Vega Masignani, Peter T. Beernink, Maria Lattanzi

“…A new method, the endogenous complement hSBA assay, has been developed to evaluate a vaccine’s ability to induce a bactericidal immune response in clinical trials, in conditions that approximate real-world settings through the use of each vaccinee’s serum as a source of complement and by testing against a panel of 110 epidemiologically representative MenB strains. …”
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The Plausibility of Distance and Computer-Assisted Learning in an era of Fuel Subsidy Removal: a Case Study of the Main Campus of Lagos State University by Мохаммед Акінола Акомолафе, Оладжиде Абіодун Обі

“…Hence, the present research offers distance computer-assisted learning via Open and Distance Learning (ODL) as a complement to traditional or conventional learning in tertiary institutions in Nigeria. …”
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Resolution of the Expert council “Unsolved problems of targeted therapy for paroxysmal nocturnal hemoglobinuria in Russia” by A. D. Kulagin, E. A. Lukina, V. V. Ptushkin, M. P. Kostinov, E. G. Arshanskaya, T. N. Babaeva, T. I. Ksenzova, Z. T. Fidarova, M. V. Marchenko

“…During the Expert Council, the following aspects of targeted APG therapy were considered: • criteria for the suboptimal response of patients with APG to therapy with inhibitors of the 5th component of complement (C5); • efficacy and safety of the use of pegcetacoplan in APG in patients with insufficient efficacy of inhibitors of the C5 component of complement; • vaccination issues before starting therapy with complement inhibitors and the possibility of conducting treatment with pegcetacoplan at home.…”
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Phospholipid Binding Protein C Inhibitor (PCI) Is Present on Microparticles Generated In Vitro and In Vivo. by Katrin Einfinger, Sigrun Badrnya, Margareta Furtmüller, Daniela Handschuh, Herbert Lindner, Margarethe Geiger

“…Among the proteins co-precipitating with protein C inhibitor, complement factors, especially complement factor 3, were most striking. …”
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Analysis of Factors Influencing Digital Transformation of Tourism Villages: Evidence from Bogor, Indonesia by Isbandriyati Mutmainah, Iis Anisa Yulia, Foni Agus Setiawan, Aditya Sugih Setiawan, Immas Nurhayati, Bambang Hengky Rainanto, Sri Harini, Endri Endri

“…The intention to implement digital transformation became a perfect part of the technological context of the commitment to implement digital transformation. …”
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Global aHUS Registry Analysis of Patients Switching to Ravulizumab From Eculizumab by Franz Schaefer, Imad Al-Dakkak, Katerina Anokhina, David Cohen, Larry A. Greenbaum, Gema Ariceta

“…Ravulizumab, a next-generation terminal complement inhibitor, provides immediate, complete, and sustained complement C5 inhibition. …”
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Exploration of plasma exosomal miR-122-5p and its related targets KNG1 and C3 in the diagnosis of drug-resistant tuberculosis by Xinyi Yao, Lahong Zhang

“…Furthermore, we employed liquid biopsy techniques to quantify miR-122-5p expression in plasma exosomes from DR-TB patients, alongside measuring plasma levels of KNG1, complement C3, and other coagulation and immune function parameters. …”
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Antibody-dependent enhancement of SARS-CoV-2, the impact of variants and vaccination by Swapna Thomas, Maria K. Smatti, Hebah Atef Mohammad AlKhatib, Yaman Tayyar, Muna Nizar, Hadeel T. Zedan, Allal Ouhtit, Asmaa A. Althani, Gheyath K. Nasrallah, Hadi M. Yassine

“…ADE was associated with reduced neutralizing antibody activity and elevated complement activation in severe infections, though the specific role of complement in ADE remains unclear. …”
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Could plasma based therapies still be considered in selected cases with atypical hemolytic uremic syndrome? by Sare Gülfem Özlü, Oğuz Söylemezoğlu, Rezan Topaloğlu, Zeynep Birsin Özçakar, Banu Acar, Mehmet Taşdemir, Elif Çomak, Elif Bahat Özdoğan, Gönül Parmaksız, Ali Delibaş, Emine Atayar, Özlem Aydoğ, Bora Gülhan, Fatih Özaltın

“…Atypical hemolytic uremic syndrome (aHUS) occurs due to defective regulation of the alternative complement pathway (ACP) on vascular endothelial cells. …”
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Severe pregnancy-associated atypical hemolytic uremia syndrome in the context of the COVID-19 pandemic: a novel survival case report by Yan Yang, Xiao-jin Li, Hua-Yan Yuan, Jing-Jing Xiong, Peng-Fei Li, Zhen Wang

“…Abstract Background Pregnancy-associated atypical hemolytic uremic syndrome (aHUS) is a form of thrombotic microangiopathy (TMA) caused by uncontrolled activation of the complement system during pregnancy or the postpartum period. …”
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Efficacy and safety of telitacicept in systemic lupus erythematosus with lupus nephritis and nephrotic syndrome: a 12-month retrospective cohort study by Min-Ying Liu, Min-Ying Liu, Min-Ying Liu, Liu-Jun Li, Ting Li, Hao-Sen Zhu, Hao-Sen Zhu, Chang-Song Lin, Chang-Song Lin, Chang-Song Lin, Qiang Xu, Qiang Xu, Qiang Xu, Qing-Ping Liu, Qing-Ping Liu, Qing-Ping Liu

“…Primary endpoints include changes in Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) scores, 24-h urinary protein excretion (24hUpr), complement levels (Complement Component 3/Complement Component 4), anti-double-stranded DNA antibodies (anti-dsDNA) titers, immunoglobulin profiles, serum creatinine, and hemoglobin (HGB) at baseline, 3-month, and 12-month intervals. …”
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Mediating role of psychological resilience between depression and humoral immunological biomarkers in medical staff by Yunyun MA, Yanshuan WEI, Lili QIAN, Xiufeng ZUO, Dechao WANG, Shanfa YU

“…Serum immunoglobulin (Ig) M (IgM), IgG, IgA, complement 3 (C3), and complement 4 (C4) were detected in fasting venous blood samples. …”
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Atypical Hemolytic Uremic Syndrome Precipitated by Recurrent Pancreatitis by Nivine El-Hor, Kyle Kondrat, Suresh Balasubramanian

“…Here, we report a case of complement-mediated atypical hemolytic uremic syndrome likely precipitated by recurrent alcohol-induced pancreatitis.…”
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