Implementation of an intervention to scale up coverage of pneumonia management in children younger than 5 years in a north Indian district: protocol for a quasi-experimental, mixed-methods, pre-post implementation study by Shamim Qazi, Sarmila Mazumder, Naveen Garg, Yasir Bin Nisar, Barsha Gadapani Pathak, Tarun Madhur

“…The Government of India revised their Childhood Pneumonia Management Guidelines in 2019 to improve under-five pneumonia prevention and management. This implementation study aims to achieve a high population-based coverage of pneumonia treatment for under 5 yearold children in the Palwal district of India.Method and analysis This implementation study uses a quasi-experimental pre-post design and a mixed-methods approach, conducted in three phases: (i) formative research, (ii) model optimisation through iterative testing in a learning block and (iii) scale-up and concurrent evaluation. …”
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Pulse oximetry and oxygen services for under-five children with community-acquired pneumonia attending primary and secondary level health facilities in Lagos, Nigeria (INSPIRING-Lagos): a pre-implementation and post implementation study by Hamish R Graham, Adegoke G Falade, Tim Colbourn, Eric D McCollum, Ayobami Adebayo Bakare, Carina King, Marco Ricci, James Beard, Christine Cassar, Obioma C Uchendu, Agnese Iuliano, Adamu Isah, Adams Osebi, Tahlil Ahmed, Rochelle Ann Burgess, Samy Ahmar, Paula Valentine, Ibrahim Haruna, Abdullahi Magama, Ibrahim Seriki, Temitayo Folorunso Olowookere, Matt MacCalla, Obioma Uchendu, Julius Salako, Funmilayo Shittu, Damola Bakare, Omotayo Olojede, Omotayo Emmanuel Olojede

“…Oxygen use for children with hypoxaemia increased from baseline 10/105 (10%) to 13/55 (24%) during implementation (aOR 3.01 (95% CI 1.05, 8.65), p=0.040). …”
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Barriers and facilitators to implementing a task-sharing mental health intervention for Sickle Cell Disease populations in low- and middle-income countries: a qualitative analysis using the Consolidated Framework for Implementation Research (CFIR) by John Patena, Leah Elster, Tania Hameed, Sumedha Kulkarni, Alden Yuanhong Lai, Annika C. Sweetland, Joyce Gyamfi, Temitope Ojo, Angela Odoms-Young, Charmaine Royal, Emmanuel Peprah

“…One solution is the implementation of task-sharing interventions such as the Friendship Bench which utilizes concepts of problem-solving therapy (PST). …”
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Subnational introduction of the RTS,S/AS01E malaria vaccine into routine immunization: experience and lessons from the three pilot countries by Rose Jalang’o, Kwame Amponsa-Achiano, Mike Chisema, Keziah Malm, Lydiah Khalayi, Brenda Mhone, Wahjib Mohammed, Franklin Asiedu-Bekoe, Adam Haji, Josephine Njoroge, Boston Zimba, Esther Chirwa, Peter O. Tweneboah, Jackson Sillah, Mgaywa G. M. D. Magafu, Cynthia Bergstrom, Tracey Goodman, Jenny Walldorf, Kristen Kelleher, Eliane Pellaux-Furrer, Mary J. Hamel, Michael R. Adjei, Rafiq N. A. Okine

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Understanding school frontline workers’ early implementation behavior: insights from the generation healthy kids study in Denmark by Jonas Vestergaard Nielsen, Sofie Koch, Tine Hyldahl Henriksen, Rikke Fredenslund Krølner, Line Lund, Louise Ayoe Sparvath Brautsch, Line Kattai Ulrikkeholm, Camilla Trab Damsgaard, Malte Nejst Larsen, Thomas Skovgaard

Subjects: “…implementation research…”
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A pragmatic randomized trial to compare strategies for implementing primary HPV testing for routine cervical cancer screening in a large healthcare system by Chun R. Chao, Nancy Cannizzaro, Erin E. Hahn, Ernest Shen, Chunyi Hsu, Quyen Ngo-Metzger, Michael K. Gould, Corrine E. Munoz-Plaza, Michael H. Kanter, Patricia Wride, Lena H. Ajamian, Melissa Hodeib, Benjamin I. Broder, Ivette T. Curiel, Alicia Castaneda, Stephanie K. Ong, Krishnansu Tewari, Ramez N. Eskander, Devansu Tewari, Brian S. Mittman

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Study protocol for a stepped-wedge implementation study investigating the intersectoral collaboration of implementing the TREAT INTERACT intervention for primary school teachers and the mhGAP for health care workers for child mental health promotion in Uganda by Ane-Marthe Solheim Skar, Ingunn Marie S. Engebretsen, Nora Braathu, Harriet Aber, Harald Bækkelund, Melf-Jakob Kühl, Marjorie Mukisa, Joyce Sserunjogi Nalugya, Norbert Skokauskas, Vilde Skylstad, Tore Wentzel-Larsen, TREAT research consortium, Juliet Ndimwibo Babirye

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Implementation of a COVID-19 Genomic Surveillance Regional Network for Latin America and Caribbean region. by Juliana Almeida Leite, Andrea Vicari, Enrique Perez, Marilda Siqueira, Paola Resende, Fernando Couto Motta, Lucas Freitas, Jorge Fernandez, Barbara Parra, Andrés Castillo, Rodrigo Fasce, Alexander Augusto Martinez Caballero, COVID-19 Genomic Surveillance Regional Network, Lionel Gresh, Sylvain Aldighieri, Jean-Marc Gabastou, Leticia Franco, Jairo Mendez-Rico

“…Here we describe the implementation of the COVID-19 Genomic Surveillance Regional Network in the Americas region during the beginning of the pandemic. …”
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Watershed-scale dispersal patterns of juvenile Chinook Salmon (Oncorhynchus tshawytscha) revealed through genetic parentage analysis by Matthew J. Kaylor, Lindsy R. Ciepiela, Melody Feden, Joseph T. Lemanski, Casey Justice, Benjamin A. Staton, Jonathan B. Armstrong, Stefan Kelly, Shawn R. Narum, Ian A. Tattam, Seth M. White

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Identification of FANCG as a prognostic factor for prostate cancer by Wenlong Gao, Peng Liu, Han Xinyue, Yuanjie Niu, Wu Yi

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Single-cell transcriptome analysis reveals cellular heterogeneity in the aortas of Takayasu arteritis by Na Gao, He Tang, Taotao Li, Yi Yang, Honglei Zhao, Longfei Wang, Yanqiu Guo, Bokang Qiao, Lili Pan

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Outcome of Patients Transplanted for C3 Glomerulopathy and Primary Immune Complex-Mediated Membranoproliferative Glomerulonephritis by Matthieu Halfon, Patrick Taffé, Christian Bucher, Fadi Haidar, Uyen Huynh-do, Laila-Yasmin Mani, Thomas Schachtner, Caroline Wehmeier, Jean-Pierre Venetz, Manuel Pascual, Fadi Fakhouri, Dela Golshayan, Patrizia Amico, John-David Aubert, Vanessa Banz, Sonia Beckmann, Guido Beldi, Christoph Berger, Ekaterine Berishvili, Isabelle Binet, Pierre-Yves Bochud, Sanda Branca, Heiner Bucher, Emmanuelle Catana, Yves Chalandon, Sabina De Geest, Sophie De Seigneux Michael Dickenmann, Joëlle Lynn Dreifuss, Michel Duchosal, Thomas Fehr, Sylvie Ferrari-Lacraz, Christian Garzoni, Christophe Gaudet, Déla Golshayan, Nicolas Goossens, Jörg Halter, Dominik Heim, Christoph Hess, Sven Hillinger, Hans H. Hirsch, Patricia Hirt, Günther Hofbauer, Uyen Huynh-Do, Franz Immer, Michael Koller, Mirjam Laager, Bettina Laesser, Frédéric Lamoth, Roger Lehmann, Alexander Leichtle, Oriol Manuel, Hans-Peter Marti, Michele Martinelli, Valérie McLin, Katell Mellac, Aurelia Mercay, Karin Mettler, Nicolas J. Mueller, Antonia Müller, Ulrike Müller-Arndt, Beat Müllhaupt, Mirjam Nägeli, Graziano Oldani, Manuel Pascual, Jakob Passweg, Klara Posfay-Barbe, Juliane Rick, Anne Rosselet, Simona Rossi, Silvia Rothlin, Frank Ruschitzka, Thomas Schachtner, Urs Schanz, Stefan Schaub, Simon Schwab, Aurelia Schnyder, Macé Schuurmans, Thierry Sengstag, Federico Simonetta, Jürg Steiger, Guido Stirniman, Ueli Stürzinger, Christian Van Delden, Jean-Pierre Venetz, Jean Villard, Julien Vionnet, Madeleine Wick, Markus Wilhlem, Patrick Yerly

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Protection against prolonged pneumococcal infection involves structural changes in C-reactive protein and subsequent binding to both phosphocholine and amyloids on the bacterial su... by Alok Agrawal, Donald N. Ngwa, J. Paul Simons, Sanjay K. Singh

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Pilot Study of sC5b-9 and Bb Fragment Plasma Levels in Crescentic Immunoglobulin A Nephropathy by Gabriella Guzzo, Salima Sadallah, Valentin Rousson, Francisco Herrera-Gómez, Giuseppe Pantaleo, Manuel Pascual, Daniel Teta

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The Generation of a H9N2 Avian Influenza Virus with HA and C3d-P29 Protein Fusions and Vaccine Development Applications by Xue Pan, Fan Zhou, Xiaona Shi, Qinfang Liu, Dawei Yan, Qiaoyang Teng, Chunxiu Yuan, Bangfeng Xu, Zhifei Zhang, Minghao Yan, Zejun Li

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Obesity enhances ovarian cancer chemotherapy efficacy through C1q-mediated tumor targeting and immune activation by Shiyi Xu, Nana Bie, Xinzhuang Su, Xiaojuan Zhang, Shiyu Li, Haojie Liu, Tuying Yong, Qing Chen, Xiangliang Yang, Lu Gan

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Common Solutions to Stein Inequalities by Birgül Aksoy, Şerife Yılmaz

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Genetic markers involved in neuroinflammation in Down syndrome: a systematic review by Marina Nascimento Silva, Mariana Dias Lula, Lucas Reis Felício, Bárbara Santos, Lívia Silva Nassif, Marcus Carvalho Borin, Juliana Alvares-Teodoro, Francisco de Assis Acurcio, Augusto Afonso Guerra Júnior

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Phenotypic manifestation of homozygous partial deletion of the chromosome 1 segment spanning <i>CFHR3</i> region by I. A. Tuzankina, M. A. Bolkov, N. S. Zhuravleva, Yu. O. Vaseneva, Kh. Shinvari, O. V. Schipacheva

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Expert consensus on the management of pharmacodynamic breakthrough-hemolysis in treated paroxysmal nocturnal hemoglobinuria by David Dingli, Carlos De Castro III, Jamie Koprivnikar, Austin Kulasekararaj, Jaroslaw Maciejewski, Brian Mulherin, Jens Panse, Vinod Pullarkat, Alexander Röth, Jamile Shammo, Louis Terriou, Ilene Weitz, Irina Yermilov, Sarah Gibbs, Michael Broder, David Beenhouwer, David Kuter

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