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    Case Report: Failure of eculizumab to block complement to prevent relapse of anti-phospholipid syndrome in kidney transplant recipient by Thibault Laban, Fredéric Pigneur, Constance Guillaud, Marie Agnès Dragon Durey, Marie Agnès Dragon Durey, Houcine Hamidi, Caroline Pilon, Caroline Pilon, Marc Michel, Nizar Joher, Philippe Grimbert, Philippe Grimbert, Philippe Grimbert, Hamza Sakhi, Hamza Sakhi, Antoine Morel, Marie Matignon, Marie Matignon, Marie Matignon

    Published 2025-06-01
    “…Catastrophic antiphospholipid syndrome (CAPS) leads to organ dysfunction due to thrombotic microangiopathy (TMA). Complement may play a role in CAPS, and its blockade could prevent antiphospholipid syndrome (APS) complications after kidney transplantation (KT). …”
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    A nanoluciferase complementation-based assay for monitoring β-arrestin2 recruitment to the dopamine D3 receptor by Viktor Burström, Kuiying Xu, Emilio Garro-Martínez, Robert H. Mach, Kristoffer Sahlholm, Nibal Betari

    Published 2025-06-01
    “…Luciferase complementation assays have emerged as a simple means of monitoring receptor-effector interactions in living cells in a time-resolved manner. …”
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    Astrocyte-derived complement C3 facilitated microglial phagocytosis of synapses in Staphylococcus aureus-associated neurocognitive deficits. by Haifang Zhang, Qiyuan Jin, Jijie Li, Jiali Wang, Mengqi Li, Qiao Yin, Qi Li, Yuwan Qi, Lingling Feng, Liang Shen, Yuan Qin, Qifei Cong

    Published 2025-04-01
    “…Our findings indicate that the complement C1q and C3 are upregulated, and astroglial release of C3 activates microglia to phagocytose synapses. …”
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    Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility. by Jian Zhao, Hui Wu, Melanie Khosravi, Huijuan Cui, Xiaoxia Qian, Jennifer A Kelly, Kenneth M Kaufman, Carl D Langefeld, Adrienne H Williams, Mary E Comeau, Julie T Ziegler, Miranda C Marion, Adam Adler, Stuart B Glenn, Marta E Alarcón-Riquelme, BIOLUPUS Network, GENLES Network, Bernardo A Pons-Estel, John B Harley, Sang-Cheol Bae, So-Young Bang, Soo-Kyung Cho, Chaim O Jacob, Timothy J Vyse, Timothy B Niewold, Patrick M Gaffney, Kathy L Moser, Robert P Kimberly, Jeffrey C Edberg, Elizabeth E Brown, Graciela S Alarcon, Michelle A Petri, Rosalind Ramsey-Goldman, Luis M Vilá, John D Reveille, Judith A James, Gary S Gilkeson, Diane L Kamen, Barry I Freedman, Juan-Manuel Anaya, Joan T Merrill, Lindsey A Criswell, R Hal Scofield, Anne M Stevens, Joel M Guthridge, Deh-Ming Chang, Yeong Wook Song, Ji Ah Park, Eun Young Lee, Susan A Boackle, Jennifer M Grossman, Bevra H Hahn, Timothy H J Goodship, Rita M Cantor, Chack-Yung Yu, Nan Shen, Betty P Tsao

    Published 2011-05-01
    “…Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins (CFHR1-CFHR5) within the chromosome 1q32 locus linked to SLE, have been associated with multiple human diseases and may contribute to dysregulated complement activation predisposing to SLE. …”
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    Impact of preoperative complement-dependent cytotoxicity crossmatch on postoperative outcomes in kidney transplant recipients: A retrospective analysis by Chonghe Xu, Siqi Xie, Meiyi Lu, Wei Xu, Mei Zhu

    Published 2025-04-01
    “…Objectives The aim of the present study was to compare the differences in clinical outcomes within 6 months postoperatively between a complement-dependent cytotoxicity <10% group of low-risk kidney transplant patients and a complement-dependent cytotoxicity ≥10% group of relatively high-risk patients. …”
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    Early crowd forecasting away from stations by geographically complemented regression using transit search and mobility logs by Soto Anno, Kota Tsubouchi, Masamichi Shimosaka

    Published 2025-07-01
    “…To address this issue, this paper presents an early crowd forecasting method capable of predicting crowding a week in advance in both station vicinities and areas away from stations by introducing an innovative crowd forecasting model called geographically complemented multi-task Poisson regression (GCPR). Our method infers the flows of people after they arrive at railroad stations based on GPS-based mobility logs and transit search logs by leveraging the heterogeneous characteristics of nearby stations. …”
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