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11681
Clarification and Prioritization of Omnichannel Marketing Antecedents: A Meta-Synthesis Approach
Published 2024-12-01“…Recognizing the significance of this topic, a qualitative framework for implementing omnichannel marketing was developed through this study. …”
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11682
Optimal Temperature Calculation for Multicriteria Optimization of the Hydrogenation of Polycyclic Aromatic Hydrocarbons by NSGA-II Method
Published 2024-03-01“…The research objective is to create a program implementing the multicriteria optimization non-dominated sorting genetic algorithm-II (NSGA-II). …”
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11683
STRATEGIC COMPETENCE AS A GUARANTEE OF PROFESSIONAL ACTIVITY OF A MODERN IT SPECIALIST
Published 2023-07-01“…The importance of shaping strategic competence in three main sections is substantiated including: elemental (a set of components, the interaction between which ensures the implementation of the relevant activity); functional (methodology for adopting strategies); and procedural (technology for developing and implementing a strategy in the existing environment). …”
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11684
The possibility of using e-learning tools for the development of the cognitive activity of students
Published 2018-05-01“…E-learning tools not only complement the educational process, but also become an integral part to increase efficiency and learning outcome. …”
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11685
Delayed Onset of Thrombotic Microangiopathy (TMA) upon Prolonged Carfilzomib Therapy in Multiple Myeloma: A Case Report and Comprehensive Review
Published 2024-12-01“…An immediate workup raised a strong suspicion for TMA, confirmed by laboratory findings of schistocytosis and complement activation. Following the immediate discontinuation of carfilzomib, the patient underwent 18 plasmapheresis (PEX) sessions and received supportive fresh frozen plasma transfusions, which resulted in the complete remission of TMA symptoms without the need for complement inhibitory therapy. …”
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11686
Atheroembolic Kidney Disease and Atypical Hemolytic Uremic Syndrome: Two Sides of the Same Coin?
Published 2025-01-01“…The embolization of cholesterol crystals in the renal artery activates the complement and triggers an inflammatory reaction. Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy caused by the hyperactivation of the alternative complement pathway, leading to a prothrombotic and proinflammatory state on the endothelial surface. …”
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11687
Atypical Hemolytic Uremic Syndrome Triggered by COVID‐19 Infection in a Pediatric Patient With CD46 Mutation
Published 2025-03-01“…This case highlights the potential of COVID‐19 to trigger complement‐mediated TMA and emphasizes the importance of prompt diagnosis, genetic assessment, and targeted complement inhibition in managing aHUS.…”
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11688
A Novel Way to Relate Ontology Classes
Published 2015-01-01“…As a result, there is a possibility that the tools will produce error prone inference results for relations, namely, sub-, union, intersection, equivalent relations, and those dependent on these relations, namely, complement. To verify whether a class is complement of other involves utilization of sub- and equivalent relations. …”
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11689
Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of ALXN1820 (Tarperprumig) in Healthy Adults: Results of a Phase I Study
Published 2025-04-01“…ABSTRACT Properdin is an endogenous positive regulator of the complement alternative pathway (AP). Tarperprumig (ALXN1820), a novel humanized bispecific antibody, binds properdin and albumin and is being developed to treat complement‐mediated diseases. …”
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11690
Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis.
Published 2017-03-01“…Unlike its native counterpart, rSALO(P) does not inhibit the classical pathway of complement; however, antibodies to rSALO(P) inhibit the anti-complement activity of sand fly salivary gland homogenate. …”
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11691
C1 esterase inhibitor reduces lower extremity ischemia/reperfusion injury and associated lung damage.
Published 2013-01-01“…C1 INH did not primarily act via inhibition of the complement system, but via the kinin and coagulation cascade. …”
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11692
Renal Transplant Patients Biopsied for Cause and Tested for C4d, DSA, and IgG Subclasses and C1q: Which Humoral Markers Improve Diagnosis and Outcomes?
Published 2017-01-01“…Cumulative DSA above 10,000 MFI were associated with C4d deposition and complement fixation. There was no significant correlation between graft loss and C1q positivity, and IgG subclass analysis seemed to be a better correlate for complement fixing antibodies in the C4d+ patient group.…”
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11693
Urinary V‐Set Ig Domain‐Containing Protein 4 and Immune Complexes for Tracking Lupus Nephritis and Renal Pathology
Published 2025-05-01“…Objective This study aims to investigate whether V‐set Ig domain‐containing protein 4 (VSIG4; also known as complement receptor of the Ig superfamily [CRIg]) forms immune complexes (ICxs) with IgG and complement component 3 (C3) in the kidneys of patients with lupus nephritis (LN) and to assess the potential of urinary VSIG4 and VSIG4‐ICx as noninvasive biomarkers of LN. …”
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11694
A Digital Photo Activity Intervention for Nursing Home Residents With Dementia and Their Carers: Mixed Methods Process Evaluation
Published 2025-04-01“…ObjectiveBy tracing facilitators and barriers to implementation, the study also aimed to inform future implementation of the photo activity intervention. …”
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11695
Time for change is now: Experiences of participants in a community-based approach for iron and folic acid supplementation in a rural county in Kenya, a qualitative study.
Published 2020-01-01“…Using Community Health Volunteers (CHVs) to distribute IFAS has not been implemented in Kenya before.<h4>Methods</h4>Following an intervention study implementing a community-based approach for IFAS in five public health facilities in Lari Sub-County, 19 interviews were conducted among CHVs, nurses and pregnant women participating to describe their experiences. …”
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11696
Strengthening research preparedness for crises: lessons from Norwegian government agencies in using randomized trials and quasi-experimental methods to evaluate public policy inter...
Published 2025-01-01“…Abstract During public health crises such as pandemics, governments must rapidly adopt and implement wide-reaching policies and programs (“public policy interventions”). …”
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11697
Plasma biomarkers of brain atrophy in Alzheimer's disease.
Published 2011-01-01“…These proteins are complement components C3 and C3a, complement factor-I, γ-fibrinogen and alpha-1-microglobulin. …”
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11698
<p>Glandular and non-glandular cuticular organs on the idiosoma of Gamasina mites (Acari: Mesostigmata)</p>
Published 2025-01-01“… The idiosoma of orthoadenic Gamasina (Mesostigmata) bears a maximum complement of 47 pairs of discernible cuticular organs that are distinct from setae. …”
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11699
Protective role for properdin in progression of experimental murine atherosclerosis.
Published 2014-01-01“…Deficiency of Factor B of the alternative pathway (AP) of complement is beneficial in LDLR(-/-) mice fed a high fat diet. …”
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11700
Proteasome inhibitors related thrombotic microangiopathy: a systematic and comprehensive review
Published 2024-11-01“…Comprehensive evaluation of the complement system, including genetic mutations, function, and associated complement inhibitory factor antibodies, should be included in the assessment of PI-TMA. …”
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