Analysis of prognostic factors and risk prediction in brain metastases: a SEER population-based study by Qiang Ji, Qiang Ji, Zixuan Yang, Zixuan Yang, Xun Kang, Lili Zhou, Feng Chen, Wenbin Li, Wenbin Li

“…Overall survival (OS) was evaluated using Kaplan-Meier curves and log-rank tests, complemented by multivariate Cox regression analysis. …”
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PD-1/PD-L1 and coronary heart disease: a mendelian randomization study by Liangjia Zeng, Liangjia Zeng, Liangjia Zeng, Yinglan Liang, Yinglan Liang, Ruoyun Zhou, Ruoyun Zhou, Wenting Yang, Wenting Yang, Kexin Chen, Kexin Chen, Baixin He, Baixin He, Yuqing Qiu, Yuqing Qiu, Linglong Liu, Linglong Liu, Deyang Zhou, Deyang Zhou, Zhaolin Xiao, Zhaolin Xiao, Haowen Liang, Haowen Liang, Binghua Zhang, Binghua Zhang, Renyu Li, Renyu Li, Lihong Yu, Min Yi, Xiaozhen Lin

“…Thus, we conducted this mendelian randomization analysis (MR) to estimate the causal relationship between PD-1/PD-L1 and 5 specific CHDs (chronic ischemic heart disease, acute myocardial infarction, angina pectoris, coronary atherosclerosis, and unstable angina pectoris), complemented by gene set enrichment analysis (GSEA) for further validation.MethodsPublicly available summary-level data were attained from the UK Biobank with genetic instruments obtained from the largest available, nonoverlapping genome-wide association studies (GWAS). …”
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CuddleCard: Protocol for a randomized controlled trial evaluating the effect of providing financial support to low-income mothers of preterm infants on parental caregiving in the n... by Margaret McConnell, Alya Alsager, Plyce Fuchu, Shrivaths Sriprasad, Lindsey Simoncini, Mari-Lynn Drainoni, Erika G. Cordova-Ramos, Michelle-Marie Peña, Laura Madore, Nikita S. Kalluri, Michael Silverstein, Heather Schofield, Martha J. Farah, Günther Fink, Margaret G. Parker

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Circ_0001944 Targets the miR-1292-5p/FBLN2 Axis to Facilitate Sorafenib Resistance in Hepatocellular Carcinoma by Impeding Ferroptosis by Jing F, Shi Y, Jiang D, Li X, Sun J, Guo Q

“…Furthermore, mRNA-Seq, Gene Ontology (GO) function and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis for the downstream genes involved in the “circRNA-miRNA-mRNA” network was implemented. Iron detection assay, Lipid peroxidation quantification assay, ROS measurement assay, CCK-8 assay, and tumor challenge in vivo were used to determine the mechanisms promoting sorafenib resistance in HCC, where the “circRNA-miRNA-mRNA” network is clearly involved in.Results: : circ_0001944 and circ_0078607 with upregulation and 2 downregulated expressed circRNAs (circ_0002874 and circ_0069981), as well as 11 upregulated miRNAs including miR-193a-5p, miR-197-3p, miR-27a-5p, miR-551b-5p, miR-335-3p, miR-767-3p, miR-767-5p, miR-92a-1-5p, miR-92a-3p, miR-3940-3p, and miR-664b-3p and 3 downregulated expressed miRNAs (miR-1292-5p, let-7c-5p, and miR-99a-5p) in sorafenib-resistant HCC cells were determined. …”
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The effect of minimum volume standards in hospitals (MIVOS): a systematic review by Dawid Pieper, Tim Mathes, Stefanie Pfisterer-Heise, Julia Scharfe, Charlotte Mareike Kugler, Alexander Pachanov, Zhentian Zhang, Johannes Morche

“…As a policy response to this, several countries have implemented minimum volume standards. However, there is currently a lack of systematically compiled evidence assessing their impact. …”
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Navigating the Ethical Terrain of AI-Generated Text Tools: A Review by Yasir Abdelgadir Mohamed, Abdul Hakim H. M. Mohamed, Akbar Khanan, Mohamed Bashir, Mousab A. E. Adiel, Muawia A. Elsadig

“…The study provides precise guidelines for the ethical development and implementation of AI, highlighting the need to strike a balance between technical progress and ethical concerns to guarantee that AI technologies have a beneficial effect on society while protecting human values. …”
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Research on adaptability of fracturing technologies for CBM horizontal wells based on the viewpoint of “unblocking and channeling” by Yuhang XIAO, Qingzhong ZHU, Qun ZHAO, Meizhu WANG, Yang ZHAO, Qinping SUN, Sanshuai WANG, Zongyuan LI, Qing DONG, Zihan WANG, Zhi ZHOU, Jigang GUO

“…The results show: With the increase of burial depth and geo-stress, the difficulty of coal reservoir stimulation has shifted from easy to filter out, prone to excessive opening of natural fractures near the wellbore, making it difficult to create dominant main fracturing fractures, to difficulty in gradually opening natural fractures around the dominant main fracturing fractures, insufficient opening of secondary fractures, and difficulty in transporting fracturing sand, making it easy for desanding and sand-block.Due to the excessive pressure loss along the wellbore, the bottom sealing drag fracturing technology is unable to meet the needs of “unblocking and channeling”fracturing stimulation at depths of more than 1 000 meters.The continuous tubing fracturing technology has the problem of insufficient carrying capacity for fracturing sand after at depths exceeding 1 200 meters.The bridge shooting combined fracturing technology can not only meet the needs of the “Unblocking and Channeling” fracturing stimulation of coal reservoirs with a depth of 1 250 meters, but also has the potential to further increase the scale of fracturing stimulation, which can meet the construction and implementation of the“unblocking and channeling”fracturing stimulation of coal reservoirs under deeper conditions. …”
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Impacto de la Telerehabilitación en Fibromialgia: Ejercicio, Educación y su Influencia en Dolor, Calidad de Vida, Catastrofización y Sueño (Impact of Telerehabilitation in Fibromya... by Wilson Francisco Pasten Hidalgo, Diego Huerta Iglesias, Felioe Gillies Herreros, Paula Moreno Reyes, Sergio Jimenez Torres, Aldo Vera Calzaretta

“…Objective: This study aimed to investigate the combined effects of physical exercise and pain management education, implemented through telerehabilitation, in women with fibromyalgia. …”
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Cognitive-bias modification intervention to improve physical activity in patients following a rehabilitation programme: protocol for the randomised controlled IMPACT trial by Stéphane Cullati, Axel Finckh, Delphine S Courvoisier, Boris Cheval, Matthieu P Boisgontier, Reinout W Wiers, Silvio Maltagliati, Layan Fessler, David Sander, Malte Friese, Christophe Luthy

“…Recent research on automatic factors (eg, automatic approach tendencies) may provide additional targets for interventions. However, the implementation and evaluation of intervention designed to change these automatic bases of PA are rare. …”
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GENDER PECULIARITIES OF THE SPECTRUM OF CHROMOSOMAL ABERRATIONS IN PERIPHERAL BLOOD LYMPHOCYTES OF HEALTHY PERSONS AND PATIENTS WITH GENERALIZED PERIODONTITIS by M. I. Khomyk, L. Ye. Kovalchuk, H. M. Melnychuk

“…The presence of dicentric chromosomes (dicentrics) in patients with GP of II-III degree of men and women showed instability of the genotype, which caused the violation of the implementation of genetic information. An increase in the number of CA in the GP may indicate a slight weakening of the protective forces of the patients’ bodies, because this precludes the elimination of cells with a broken genetic apparatus. …”
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Diagnostic properties of differing BP thresholds for adverse pregnancy outcomes in standard-risk nulliparous women: A secondary analysis of SCOPE cohort data. by Laura Slade, Maya Blackman, Hiten D Mistry, Jeffrey N Bone, Milly Wilson, Nuhaat Syeda, Lucilla Poston, Peter von Dadelszen, Laura A Magee, SCOPE Consortium

“…This study does not support implementation of lower BP values as abnormal in nulliparous pregnant women.…”
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Building Epidemiological Capacity for Health Security in Liberia by Muhammad Shakir Balogun, Maame Amo Addae, Himiede Wede Wilson

“…The first paper in this supplement is a report of the implementation of this critical capacity building and health systems strengthening effort. …”
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Engagement With Digital Adherence Technologies as Measures of Intervention Fidelity Among Adults With Drug-Susceptible Tuberculosis and Health Care Providers: Descriptive Analysis... by Jason Alacapa, Amare Worku Tadesse, Natasha Deyanova, Tanyaradzwa Dube, Andrew Mganga, Rachel Powers, Job van Rest, Norma Madden, Egwuma Efo, Salome Charalambous, Kristian van Kalmthout, Degu Jerene, Katherine Fielding

“…ConclusionsThere was considerable variation in DAT engagement across countries and DAT types, reflecting differences in how the intervention was implemented. Further refinement of the intervention and improvements in its delivery may be necessary to enhance outcomes.…”
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التحديات التي تواجه التنمية الاقتصادية في العراق وسبل معالجتها by ناجي ساري فارس

“…وكذلك تدهور الوضع الأمني بعد سقوط النظام السابق ولحد الان.كل ذلك أدى إلى زیادة التحدیات وتعددها، مما أثر سلباً على الاقتصاد الع ا رقي بمختلف قطاعاته الاقتصادیة.ویعد الاقتصاد الع ا رقي من الاقتصادات الریعیة فلابد من توظیف الموارد النفطیة في بناء اقتصاد قوي یؤدي الى زیادة مستمرة في التشغیل والقدرة على القطاعات الاقتصادیة المختلفة في زیادة الإنتاج وعدم الاعتماد على القطاع النفطي، وكذلك الاعتماد على التخطیط الشامل في القطاعات الاقتصادیة المختلفة.وهذا ما یؤدي إلى معالجة التحدیات من أجل تحقیق أهداف التنمیة الاقتصادیة في الع ا رق Abstract The goal of the economic development process of the elimination Of the causes of underdevelopment and the reduction of Unemployment,A radical change in the community,By improving Citizens to achieve their Hopes of a decent life in accordance with Health, education and social Standards.After I finished many heavy Government intervention in Economic life strategies countries,and the Concomitant administrative Procedures for the public sectorin order to Influence a simple, Government intervention on the economic Sectors of the state,Which Led to many cons in these strategies, has Had a direct impact on the Incidence and socioeconomic and political Changes in these countries Have implemented these strategies in the Wake of the political Independence of those countries, including Iraq.Challenges facing the Iraqi economy because of the wrong economic policies has begun, and You do not specify the errors and structural Imbalances various economic Sectors,As the decline in oil prices has Caused a significant decline in Financial returns, leaving raised in Development plans for Iraq, has Economic sanctions on Iraq have Contributed to the deepening of the Failure of the Iraqi economy,Which led to the obstruction of the Development process because of the Failure of economic, performance Indicators of economic sectors, and The prevalence of the phenomenon Of unemployment and inflation and Economic and financial corruption.As well as the deterioration of the Security situation after the fall of the Former regime and until now. …”
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Investigation of the efficiency of different reprocessing methods on disposable laryngeal masks contaminated with HBV DNA by Gökahmetoğlu, Günhan, Renders, Duygu Perçin, Gökahmetoğlu, Selma, Biçer, Cihangir, Aksu, Recep, Çevik, Şerife

“…Also, thermal disinfection (A3000) +5 minutes steam sterilization at 134°C was implemented only to reusable LM. At least three LM were used for each group. …”
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Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis. by Tom G Richardson, Eleanor Sanderson, Tom M Palmer, Mika Ala-Korpela, Brian A Ference, George Davey Smith, Michael V Holmes

“…Using genetic instruments for lipoprotein lipid traits implemented through multivariable Mendelian randomisation (MR), we sought to compare their causal roles in the aetiology of CHD.…”
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Deteksi Dan Klasifikasi Hama Potato Beetle Pada Tanaman Kentang Menggunakan YOLOV8 by Daniel Geoffrey Manurung, Mohammad Ryan Pinasthika, Muhammad Azka Obila Vasya, Rania Aprilia Dwi Setya Putri, Agustinus Parasian Tampubolon, Rakan Fadhil Prayata, Septia Khoirin Nisa, Novanto Yudistira

“…The YOLOv8 (You Only Look Once) model is implemented to detect objects in images, identifying the position and class of potato beetles. …”
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PSYCHOANALYTIC DIMENSIONS OF IVAN FRANKO’S GREAT PROSE OF 1887–1893 by Svitlana M. Lutsak, Nataliia M. Vivcharyk

“…The following tasks arise from the objective: To analyze the key vectors of the twin myth in the novel “Lel and Polel”; characterize the ambivalent manifestations of the Great Mother archetype in the image of the main heroine in the novel “For the Home Hearth”; identify transformations of Freudian ideas in the artistic structure of the novel “Foundations of Society”, considering their animistic component. The implementation of the set tasks necessitated the use of such methods as receptive-interpretative, psychoanalytic, mythopoetic, hermeneutic, and biographical. …”
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User-Driven Development of a Digital Behavioral Intervention for Chronic Pain: Multimethod Multiphase Study by Afra Selma Taygar, Sara Laureen Bartels, Rocío de la Vega, Ida Flink, Linnéa Engman, Suzanne Petersson, Sophie I Johnsson, Katja Boersma, Lance M McCracken, Rikard K Wicksell

“…The Consolidated Framework for Implementation Research was used to structure analyses of end-user feedback. …”
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Fatores de risco psicossocial em terapia intensiva neonatal: repercussões para a saúde do enfermeiro [Psychosocial risk factors in neonatal intensive care unit: impact to the nurse... by Elias Barbosa de Oliveira, Alexandre Vicente da Silva, Eugenio Fuentez Perez Junior, Helena Figueiredo da Costa, Luana Pedro Nascimento, Luciana Aparecida Moraes de Souza

“…Conclusions show that therefore preventive actions and changes need to me implemented by the organization so that it could improve the work environment. …”
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