A novel and rapid method to purify the human complement opsonin C3b from human plasma by Jannik Sichau, Christoph Q. Schmidt

Subjects: “…complement - immunological terms…”
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A diachronic study on the Mandarin complex directional complement guòlái ‘come over’ from the macro-event perspective by Yang Yuhang, Li Fuyin Thomas

Subjects: “…complex directional complements…”
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Astrocyte-derived complement C3 facilitated microglial phagocytosis of synapses in Staphylococcus aureus-associated neurocognitive deficits. by Haifang Zhang, Qiyuan Jin, Jijie Li, Jiali Wang, Mengqi Li, Qiao Yin, Qi Li, Yuwan Qi, Lingling Feng, Liang Shen, Yuan Qin, Qifei Cong

“…Our findings indicate that the complement C1q and C3 are upregulated, and astroglial release of C3 activates microglia to phagocytose synapses. …”
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Complement C3 inhibitor in patients with paroxysmal nocturnal hemoglobinuria with suboptimal response to C5 inhibitor therapy by M. V. Marchenko, O. U. Klimova, E. V. Anikina, A. V. Lapina, T. A. Rudakova, T. I. Ksenzova, A. D. Kulagin

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Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility. by Jian Zhao, Hui Wu, Melanie Khosravi, Huijuan Cui, Xiaoxia Qian, Jennifer A Kelly, Kenneth M Kaufman, Carl D Langefeld, Adrienne H Williams, Mary E Comeau, Julie T Ziegler, Miranda C Marion, Adam Adler, Stuart B Glenn, Marta E Alarcón-Riquelme, BIOLUPUS Network, GENLES Network, Bernardo A Pons-Estel, John B Harley, Sang-Cheol Bae, So-Young Bang, Soo-Kyung Cho, Chaim O Jacob, Timothy J Vyse, Timothy B Niewold, Patrick M Gaffney, Kathy L Moser, Robert P Kimberly, Jeffrey C Edberg, Elizabeth E Brown, Graciela S Alarcon, Michelle A Petri, Rosalind Ramsey-Goldman, Luis M Vilá, John D Reveille, Judith A James, Gary S Gilkeson, Diane L Kamen, Barry I Freedman, Juan-Manuel Anaya, Joan T Merrill, Lindsey A Criswell, R Hal Scofield, Anne M Stevens, Joel M Guthridge, Deh-Ming Chang, Yeong Wook Song, Ji Ah Park, Eun Young Lee, Susan A Boackle, Jennifer M Grossman, Bevra H Hahn, Timothy H J Goodship, Rita M Cantor, Chack-Yung Yu, Nan Shen, Betty P Tsao

“…Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins (CFHR1-CFHR5) within the chromosome 1q32 locus linked to SLE, have been associated with multiple human diseases and may contribute to dysregulated complement activation predisposing to SLE. …”
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Impact of preoperative complement-dependent cytotoxicity crossmatch on postoperative outcomes in kidney transplant recipients: A retrospective analysis by Chonghe Xu, Siqi Xie, Meiyi Lu, Wei Xu, Mei Zhu

“…Objectives The aim of the present study was to compare the differences in clinical outcomes within 6 months postoperatively between a complement-dependent cytotoxicity <10% group of low-risk kidney transplant patients and a complement-dependent cytotoxicity ≥10% group of relatively high-risk patients. …”
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Decreased concentrations of C5a complement receptor antibodies are associated with relapse in eosinophilic granulomatosis with polyangiitis (EGPA) by Gabriela Riemekasten, Sebastian Klapa, Antje Müller, Andreas Koch, Harald Heidecke, Peter Lamprecht, Wataru Kaehler, Sabrina Arnold, Anja Staehle, Christian M Karsten

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Complement Activation in Association with Markers of Neutrophil Extracellular Traps and Acute Myocardial Infarction in Stable Coronary Artery Disease by Karsten E. Kluge, Miriam S. Langseth, Trine B. Opstad, Alf Å. Pettersen, Harald Arnesen, Theis Tønnessen, Ingebjørg Seljeflot, Ragnhild Helseth

“…Complement activation and neutrophil extracellular traps (NETs) have both been suggested to drive atherosclerotic plaque progression. …”
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Early crowd forecasting away from stations by geographically complemented regression using transit search and mobility logs by Soto Anno, Kota Tsubouchi, Masamichi Shimosaka

“…To address this issue, this paper presents an early crowd forecasting method capable of predicting crowding a week in advance in both station vicinities and areas away from stations by introducing an innovative crowd forecasting model called geographically complemented multi-task Poisson regression (GCPR). Our method infers the flows of people after they arrive at railroad stations based on GPS-based mobility logs and transit search logs by leveraging the heterogeneous characteristics of nearby stations. …”
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Real-World Outcomes with Complement Inhibitors for Geographic Atrophy: A Comparative Study of Pegacetacoplan versus Avacincaptad Pegol by Rush RB, Klein W, Reinauer RM

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Complement mediated signaling on pulmonary CD103(+) dendritic cells is critical for their migratory function in response to influenza infection. by Matheswaran Kandasamy, Poon C Ying, Adrian W S Ho, Hermi R Sumatoh, Andreas Schlitzer, Timothy R Hughes, David M Kemeny, B Paul Morgan, Florent Ginhoux, Baalasubramanian Sivasankar

“…Collectively, our findings show that complement has a profound impact on immune regulation by controlling tissue DC trafficking and highlights a potential utility for complement as an adjuvant in novel vaccine strategies.…”
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Cobalt Protoporphyrin IX Attenuates Antibody-Mediated, Complement-Dependent Podocyte Injury: Role of Cobalt and Porphyrin Moieties by Elias A. Lianos, Gia Nghi Phung, Jianping Zhou, Mukut Sharma

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Structure-function analysis of CNGA3-associated achromatopsia patient variants complements clinical genomics in pathogenicity determination by Ditte K. Rasmussen, Young Joo Sun, Joel A. Franco, Aarushi Kumar, Jennifer T. Vu, Alexander G. Bassuk, Vinit B. Mahajan

“…Conclusion Thus, proteoform-based analysis can be a valuable approach for assessing novel variants and complement clinical genomics in its utilization.…”
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Fc-modification of anti-PcrV gene-encoded antibodies modulates complement-mediated killing of Pseudomonas aeruginosa by Jillian Eisenhauer, Jillian Eisenhauer, Spencer Dublin, Jihae Choi, Abigail R. Trachtman, Jacqueline D. Chu, David Custodio-Zegarra, Suman Bharti, Bhavya Bhardwaj, Shuangyi Bai, William T. Witt, Maria de la Paz Gutierrez, Sarah J. Miller, Kaitlyn Flowers, Trevor R. F. Smith, Bronwyn M. Gunn, Mariette Barbier, Elizabeth M. Parzych, David B. Weiner, Ami Patel

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Complementing but Not Replacing: Comparing the Impacts of GPT-4 and Native-Speaker Interaction on Chinese L2 Writing Outcomes by Zhaoyang Shan, Zhangyuan Song, Xu Jiang, Wen Chen, Luyao Chen

“…This study suggests that LLMs should be used to complement and not replace human language partners in the L2 pre-writing phase.…”
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Introducing multiple factor analysis (MFA) as a diagnostic taxonomic tool complementing principal component analysis (PCA) by L. Lee Grismer

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Urine Complement Factor Ba Identifies Persistent Acute Kidney Injury and Organ Failures in Critically Ill Adults by Erin K. Stenson, Charles E. Edelstein, Zhiying You, Anna Ostrow, Zoltan Endre, Shinobu Miyazaki-Anzai, Bradley P. Dixon, Halden Scott, Neil Aggarwal, Joshua M. Thurman, Jessica Kendrick

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WCN25-2419 COMPLEMENT COMPONENT 4d(C4d) DEPOSITION AND PROGNOSIS IN LUPUS NEPHRITIS by Riyadh Al-Saegh, Haider J. Kehiish, Ghadeer S. Noah, Ameer R. Al-Saegh, Maha A. Al-Mukhtar, Aya R. Al-Saegh

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Correlation between serum complement C3 levels and cognitive dysfunction in patients with end-stage renal disease by Wu Si-yang, Zhang Jin, Wang Ying, Zhang Pei, Qi Xiang-ming, Wu Yong-gui

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Susceptibility to invasive meningococcal disease: polymorphism of complement system genes and Neisseria meningitidis factor H binding protein. by Declan T Bradley, Thomas W Bourke, Derek J Fairley, Raymond Borrow, Michael D Shields, Peter F Zipfel, Anne E Hughes

“…<h4>Background</h4>Neisseria meningitidis can cause severe infection in humans. Polymorphism of Complement Factor H (CFH) is associated with altered risk of invasive meningococcal disease (IMD). …”
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