Machine learning-driven multi-targeted drug discovery in colon cancer using biomarker signatures by Tingting Liu, Lifan Zhong, Xizhe Sun, Zhijiang He, Witiao Lv, Liyun Deng, Yanfei Chen

“…The artificial intelligence model personalizes therapy by leveraging patient-specific molecular profiles, optimizing drug selection and dosage while minimizing side effects. …”
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A Composite Network for CS ISAR Integrating Deep Adaptive Sampling and Imaging by Lianzi Wang, Ling Wang, Miguel Heredia Conde, DaiYin Zhu

“…However, the existing CS ISAR imaging methods based on deep learning (DL) mainly focus on improving the performance of the reconstruction algorithm while ignoring the potential room for improvement given by the design of the measurement matrix. …”
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Energetically self-sufficient robot group study kit by M. A. Rovbo, A. A. Malyshev

“…In addition to performing the target task, ancillary tasks such as maintaining the battery level, communication with other team members in a multi-agent system, should be considered in the control algorithm of the robot, which allows to study the distribution of priorities between these objectives, as shown in the example of multicriteria optimization. …”
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Study on the calculation of surface residual deformation in goaf based on the Gudermann time function by Haiguang Du, Wenchang Wang, Zhilin Dun, Lianwei Ren, Yakun Nan

“…In order to comprehensively and effectively grasp the dynamic evolution process of surface movement and deformation, and realize the scientific and accurate residual deformation calculation of each key point of the surface in goaf, the Gudermann time function for dynamic anticipation is established by introducing the Gudermann function and optimizing it, the spatial and temporal characteristics of this function in the subsidence prediction are analyzed, and the influence law of parameter changes on the surface subsidence, subsidence velocity and subsidence acceleration curve patterns of the Gudermann time function is discussed, and the method of extracting the optimal values of the function parameters by Simulated Annealing Algorithm (SAA) is presented. …”
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Immunogenic cell death-related genes as prognostic biomarkers and therapeutic insights in uterine corpus endometrial carcinoma: an integrative bioinformatics analysis by Tianfei Yi, Zhenglun Yang, Peng Shen, Yan Huang

“…The ICD score exhibited positive correlations with immune cell infiltration, as verified by ESTIMATE, xCell, TIMER, MCPcounter, EPIC, and IPS algorithms. Finally, we found that hyper-immunogenicity may be sensitive to immunotherapy and certain drugs (AZD5991, Ibrutinib, Osimertinib, AGI-5198, Savolitinib, Sapitinib, AZ960, AZD3759 and Ruxolitinib), while PCI-34051 and Vorinostat showed sensitivity in patients with hypo-immunogenicity.DiscussionOur results demonstrate that ICD plays an important role in UCEC progression, suggesting that ICD-related markers could serve as potential targets for prognosis and treatment.…”
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A seismic random noise suppression method based on CNN-Mamba by Xiujuan WEI, Xingye LIU, Huailai ZHOU

“…The hardware-aware parallel algorithm of Mamba was employed to reduce the computational resource consumption, thus ensuring the denoising performance while enhancing computational efficiency. …”
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Machine learning and the nomogram as the accurate tools for predicting postoperative malnutrition risk in esophageal cancer patients by Zhenmeng Lin, Zhenmeng Lin, Hao He, Mingfang Yan, Xiamei Chen, Hanshen Chen, Jianfang Ke

“…While RF showed marginally higher predictive performance, the nomogram offers superior clinical interpretability, making it a practical option for individualized risk stratification.…”
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Aryana-bs: context-aware alignment of bisulfite-sequencing reads by Hassan Nikaein, Ali Sharifi-Zarchi, Afsoon Afzal, Saeedeh Ezzati, Farzane Rasti, Hamidreza Chitsaz, Govindarajan Kunde-Ramamoorthy

“…It outperforms existing methods, such as BSMAP, bwa-meth, Bismark, BSBolt, and abismal, particularly in robustness against genomic biases and alignment of longer, higher-error reads, demonstrating suitability for cancer research and cell-free DNA studies. While the Expectation-Maximization (EM) algorithm provides only modest initial improvements, it establishes a valuable framework for future refinement and potential enhancements in sensitive applications.…”
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A Framework for Autonomous UAV Navigation Based on Monocular Depth Estimation by Jonas Gaigalas, Linas Perkauskas, Henrikas Gricius, Tomas Kanapickas, Andrius Kriščiūnas

“…The solution utilizes a depth image estimation model to create an occupancy grid map of the surrounding area and uses an A* path planning algorithm to find optimal paths to end goals while navigating around the obstacles. …”
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Designing of Loss Optimum Regulator for Control of D.C. Electric Drive with Varying Inertia Moment in CoDeSys Programming System by S. O. Novikov, A. V. Paschenko

“…The given software is the most suitable for simulation and development of control system algorithms and execution of semi-full-scale tests without involvement of an actual object. …”
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Toward Digital Twin of Off-Road Vehicles Using Robot Simulation Frameworks by Arianna Rana, Antonio Petitti, Angelo Ugenti, Rocco Galati, Giulio Reina, Annalisa Milella

“…The paper presents the details of model design and implementation while investigating the best choice in developing the digital twin of off-road vehicles operating in the field. …”
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Developing and validating a machine learning-based model for predicting in-hospital mortality among ICU-admitted heart failure patients: A study utilizing the MIMIC-III database by De Su, Jie Zheng, Yue-kai Shao, Jun-ya Liu, Xin-xin Liu, Kun Yu, Bang-hai Feng, Hong Mei, Song Qin

“…LASSO regression was employed for feature selection, and various machine learning algorithms were utilized to train models, including logistic regression (LR), random forest (RF), and gradient boosting (GB), among others. …”
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A machine learning model revealed that exosome small RNAs may participate in the development of breast cancer through the chemokine signaling pathway by Jun-luan Mo, Xi Li, Lin Lei, Ji Peng, Xiong-shun Liang, Hong-hao Zhou, Zhao-qian Liu, Wen-xu Hong, Ji-ye Yin

“…We used machine learning algorithms to analyze small RNAs with significant differences between the two groups, fit the model through training sets, and optimize the model through testing sets. …”
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In-Memory Versus Disk-Based Computing with Random Forest for Stock Analysis: A Comparative Study by Chitra Joshi, Chitrakant Banchorr, Omkaresh Kulkarni, Kirti Wanjale

“…Background: The advancement of big data analytics calls for careful selection of processing frameworks to optimize machine learning effectiveness. Choosing the appropriate framework can significantly influence the speed and accuracy of data analysis, ultimately leading to more informed decision making. …”
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Monitoring and Comparative Analysis of NO₂ and HCHO in Shanghai Using Dual-Azimuth Scanning MAX-DOAS and TROPOMI by Hongmei Ren, Ang Li, Zhaokun Hu, Nannan Shao, Xinyan Yang, Hairong Zhang, Jiangman Xu, Jinji Ma

“…These findings not only reveal the spatiotemporal distribution characteristics of regional pollutants but optimize the sampling time and distance parameters for satellite–ground observation validation, providing data support for improving and enhancing the accuracy of satellite retrieval algorithms.…”
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Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study by Yunlin Yang, Jinfeng Liu, Yi Hou, Yuxun Wei, Liang Huang, Liang Huang, Wei Wei

“…Primary outcomes were in-hospital and ICU mortality, while 30-day and 90-day all-cause mortality served as secondary endpoints. …”
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Estimation of gas hydrate and free gas saturation using the rock physics model based on constrained least squares and trust region method in the Shenhu Area, South China Sea by Dajiang Meng, Dajiang Meng, Ruwei Zhang, Ruwei Zhang, Yuan Gu, Yuan Gu, Baojin Zhang, Baojin Zhang, Yunqian Lu, Yunqian Lu, Jiangnan Lin, Jiangnan Lin, Lijie Wang, Lijie Wang

“…We formulated the inversion as a multi-parameter constrained least squares problem and then used the trust region algorithm to find the optimal least-squares solution. …”
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Joint Lagrangian Relaxation and Dynamic Programming Approach for a Multi-Period Multi-Product Location-Inventory Problem by Claudio Araya-Sassi, German Paredes-Belmar, Gabriel Gutierrez-Jarpa, Ricardo Gatica Escobar

“…We propose a Lagrangian relaxation algorithm and the subgradient approach as a solution method. …”
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MAPE-ViT: multimodal scene understanding with novel wavelet-augmented Vision Transformer by Muhammad Waqas Ahmed, Touseef Sadiq, Hameedur Rahman, Sulaiman Abdullah Alateyah, Mohammed Alnusayri, Mohammed Alatiyyah, Dina Abdulaziz AlHammadi

“…The feature discrimination capability is further enhanced through optimization using the Gray Wolf algorithm. The processed features then flow into a dual-stream architecture, where an extreme learning machine handles multi-object classification, while conditional random fields (CRF) manage scene-level categorization. …”
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Enhanced Inverse Model Predictive Control for EV Chargers: Solution for DC–DC Side by Abdullah Berkay Bayindir, Ali Sharida, Sertac Bayhan, Haitham Abu-Rub

“…To address this challenge, the proposed method employs an adaptive estimation strategy utilizing a recursive least square algorithm for online dynamic model estimation. This real-time estimated model enables IMPC to predict optimal switching states with improved reliability. …”
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