Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice by Onno Kranenburg, Hergen Spits, Julien Villaudy, Madalina Cercel, Miriam Koopman, Cornelis J A Punt, Jamila Laoukili, Andre Verheem, Inne H M Borel Rinkes, Emre Küçükköse, Balthasar A Heesters, Susan van Hal, Sylvia F Boj, Jeanine M L Roodhart

“…Therapy efficacy correlated with the formation of tertiary lymphoid structures (TLS)—containing B cells and juxtaposed T cells—and with expression of an interferon-γ signature together with the B cell chemoattractant CXCL13. …”
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RNA-Seq-based analysis of transcriptomic signatures elicited by mutations conferring salt tolerance in Cucurbita pepo by Keshav Gautam, Sonsoles Alonso, Alicia García, María Segura, Álvaro Benítez, Cecilia Martínez, Manuel Jamilena

“…Improving salinity tolerance in plant breeding programs requires not only donor tolerant genotypes but also a thorough knowledge of the genes controlling the trait. …”
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Biopolymer from <i>Annona muricata</i> Residues as a Potential Sustainable Raw Material for Industrial Applications by Igor F. S. Ramos, Samuel C. Dias, Talissa B. C. Lopes, Francisco T. dos S. Silva Júnior, Ricardo de Araújo, Stanley J. C. Gutierrez, Claudia Pessoa, Josy A. Osajima, Marcia S. Rizzo, Edson C. Silva-Filho, Manuela Amorim, Óscar Ramos, Alessandra B. Ribeiro, Marcilia P. Costa

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Crucial areas of the economic analysis of public cancer care by D. A. Andreev, K. I. Polyakova, A. A. Zavyalov, T. N. Ermolaeva, A. G. Fisun, A. D. Ermolaeva, V. A. Dubovtseva, T. E. Maksimova

“…In addition, we focused on significant studies conducted either on the national or international level.Results and discussion. In principle, the structure of total costs is determined by the health policy regarding the cancer care system. …”
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Functional annotation of the Hippo pathway somatic mutations in human cancers by Han Han, Zhen Huang, Congsheng Xu, Gayoung Seo, Jeongmin An, Bing Yang, Yuhan Liu, Tian Lan, Jiachen Yan, Shanshan Ren, Yue Xu, Di Xiao, Jonathan K. Yan, Claire Ahn, Dmitry A. Fishman, Zhipeng Meng, Kun-Liang Guan, Ruxi Qi, Ray Luo, Wenqi Wang

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RETRACTED: Effects of Gallotannin-Enriched Extract of Galla Rhois on the Activation of Apoptosis, Cell Cycle Arrest, and Inhibition of Migration Ability in LLC1 Cells and LLC1 Tumo... by Mi Ju Kang, Ji Eun Kim, Ji Won Park, Hyun Jun Choi, Su Ji Bae, Sun Il Choi, Jin Tae Hong, Dae Youn Hwang

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Measuring how healthcare organizations respond after patients experience harm: perspectives and next steps by Lauge Sokol-Hessner, Lauge Sokol-Hessner, John Adams, Carole Hemmelgarn, Beth Miller, Diane O'Connor, Melissa Parkerton, Leilani Schweitzer, J. Matthew Austin, J. Matthew Austin

“…To inform implementation efforts, enable accountability, and promote innovation, it is critical to develop standardized performance measures assessing CRPs’ structure, process, and outcomes. To advance CRP measurement, an interdisciplinary workgroup from the Pathway to Accountability, Compassion, and Transparency (PACT) Leadership and Innovation Network—a group of leading healthcare organizations with CRPs—explores meaningful approaches to measurement and proposes a set of next steps. …”
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Development of genome-wide insertion/deletion markers and genetic diversity in Sipunculus nudus along the Beibu Gulf of China by Yuzhu Ni, Chunli Han, Yating Liu, Manman Li, Weijie He, Jialin Yang, Jie Zou, Huijing Peng, Pengliang Wang

“…The number of alleles, effective number of alleles, observed heterozygosity, expected heterozygosity, Shannon’s index and polymorphic information content ranged from 4 to 15 (mean of 8.875), 2.110 to 6.009 (mean of 4.110), 0.009 to 0.768 (mean of 0.232), 0.526 to 0.834 (mean of 0.734), 0.919 to 2.085 (mean of 1.576), and 0.440 to 0.816 (mean of 0.692), respectively. Population structure analysis revealed four genetically distinct subpopulations within the Beibu Gulf population. …”
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A review of circular RNAs in colorectal cancer: insights into biomarker discovery and therapeutic targeting by Sibin Nambidi, Karunakaran Bhuvaneswari Shruthi, Sujatha Padmanaban Kanimozhe, Antara Banerjee, Suresh Babu Kondaveeti, Asim K. Duttaroy, Surajit Pathak

“…Circular RNAs (circRNAs), a subclass of endogenous ncRNAs characterized by their covalently enclosed loop structure, demonstrate greater stability than linear RNAs, making them potential candidates for clinical applications. …”
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Perceptions regarding rabies prevention and control in two different community settings in Vietnam using a Q-sorting approach by Doan Hoang Phu, Trang Phuong Thao, Mai Duong Tieu, Dung Nguyen Thi Thuy, Trang Nguyen Thi Phuong, Pawin Padungtod, Dinh Bao Truong

“…Although awareness of rabies is high, structural limitations – particularly inadequate access to veterinary services – hinder effective control. …”
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Astragaloside IV attenuates podocyte apoptosis via regulating TXNIP/NLRP3/GSDMD signaling pathway in diabetic nephropathy by Zhibo Hu, Yu Zhou, Cailing Gao, Junfen Liu, Congqing Pan, Jun Guo

“…Results In vitro, AS-IV led to a significant reduction in blood urea nitrogen (BUN), urine albumen-to-creatinine ratio (UACR), serum creatinine (CREA), and hyperglycemia in db/db mice and lessen the pathological alterations in the kidney. Moreover, pyrin structural domain of the NLR family pyrin domain containing 3 (NLRP3), cleaved-caspase-1, gasdermin D (GSDMD), IL-18, and IL-1β were down-expressed and podocyte markers podocin and nphs1 were up-regulated following AS-IV intervention. …”
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Applications of Multiplex Immunohistochemistry in Evaluating Spatiotemporal Heterogeneity of T Cells by Mercedes Machuca-Ostos, Tim de Martines, Kanako Yoshimura, Junichi Mitsuda, Sumiyo Saburi, Alisa Kimura, Hiroki Morimoto, Koichi Yoshizawa, Nana Sakurai, Nanako Murakami, Kayo Kitamoto, Makoto Yasuda, Yoichiro Sugiyama, Hiroshi Ogi, Saya Shibata, Aya Miyagawa-Hayashino, Eiichi Konishi, Kyoko Itoh, Takahiro Tsujikawa, Shigeru Hirano

“…However, challenges remain in understanding the spatial and temporal profiles of T cells with differential phenotypes due to difficulties in single-cell analysis with preserved tissue structures. Here, we provide an optimized 12-marker multiplex immunohistochemical (IHC) panel and single-cell-based quantitative assessment to identify the spatial distributions of T cell phenotypes in formalin-fixed paraffin-embedded sections. …”
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Systemic biological mechanisms underpin poor post-discharge growth among severely wasted children with HIV by Evans O. Mudibo, Jasper Bogaert, Caroline Tigoi, Moses M. Ngari, Benson O. Singa, Christina L. Lancioni, Abdoulaye Hama Diallo, Emmie Mbale, Ezekiel Mupere, John Mukisa, Johnstone Thitiri, Molline Timbwa, Elisha Omer, Narshion Ngao, Robert Musyimi, Eunice Kahindi, Roseline Maïmouna Bamouni, Robert H. J. Bandsma, Paul Kelly, Andrew J. Prendergast, Christine J. McGrath, Kirkby D. Tickell, Judd L. Walson, James A. Berkley, James M. Njunge, Gerard Bryan Gonzales

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Sintesis Grafena Oksida Tereduksi Terdoping Nitrogen Dan Sulfur Dari Amonium Tiosianat Sebagai Elektroda Lawan Pada Sistem Dye Sensitized Solar Cell (DSSC) by Sayekti Wahyuningsih, Ari Handono Ramelan, Mochammad Fuad, Qonita Awliya Hanif

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Methods to improve teaching effciency for students from the People’s Republic of China at technical universities by K. P. Baslyk, V. P. Pechnikov, N. A. Tukhtarova

“…The research materials include printed works for which the appropriate methods of analysis of scientific texts are used: ● excerpts from the development programs of space industry and joint educational programs of Russia and China – aspect and diachronic method of analysis of priority areas of development of the higher school of China and promising areas of cooperation; ● the curricula of professional education in various areas and specialties of Bauman Moscow State Technical University – aspect analysis of the general provisions of engineering training programs; ● manuals on the “Basics of Rocket and Space Technology” (BRST) of Russia (USSR) and China – critical, comparative and conceptual analysis of the content features, methods and style of presentation of the material; ● BRST – aspect and phenomenological analysis of the structure and content of a special technical discipline; ● scientific works on pedagogy and psychology – aspect and system analysis of features of the education system, educational behavior and bilingual opportunities of students from China.The paper applied the problem analysis method to tackle the task in the context of publications’ shortage on teaching special technical disciplines to foreigners. …”
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Diversity and distribution of helminth communities of the rodent Akodon montensis Thomas, 1913 (Rodentia: Cricetidae: Sigmodontinae) in preserved and altered environments in the At... by Camila dos Santos Lucio, Thiago dos Santos Cardoso, Rosana Gentile, Viviane Brito Dias, Milton Cezar Ribeiro, Bernardo Rodrigues Teixeira, Paulo Sérgio D'Andrea

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United States cattle market location and annual market sales estimate dataDryad by Samuel M. Smith, Clayton Hallman, Tom Lindström, Stefan Sellman, Ryan S. Miller, Katie Portacci, Colleen T. Webb, Lindsay M. Beck-Johnson

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Identification of Genomic Regions Related to Litter Size With Divergent Selection between Iranian Indigenous Sheep Breeds and Iceland Sheep Breed using FST Unbiased Statistics by Parviz Azizi, Hossein Moradi Shahrbabak, Mohammad Moradi Shahrbabak, Mahdi Mokhber

“…It was confirmed by further population structure analysis, with FST analysis and phylogeny tree extracted from the genetic distance determination information. …”
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Evaluation of porosity, permeability, and reservoir quality of the Asmari Formation using sedimentary facies and diagenesis data in the Ahvaz oil field by Akbar Heidari, Narges Shokri, Milad Faraji

“…The extensive pore spaces within reef structures, coupled with lower cementation, contribute to these favorable properties in microfacies Mf6 and Mf7. …”
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Assessment of Early Fuchs Endothelial Corneal Dystrophy and CTG Trinucleotide Expansion Positivity Using Scheimpflug Imaging by Stanley S.J. Poh, MBBS, Kai Yuan Tey, MBBS, Gary S.L. Peh, PhD, Dawn J.H. Neo, MSc, Hla Myint Htoon, PhD, Evan K.L. Lee, Yu Qiang Soh, MBBS, V Vinod Mootha, MD, Jodhbir S. Mehta, PhD

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