The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE". by Peter Savas, Zhi Ling Teo, Christophe Lefevre, Christoffer Flensburg, Franco Caramia, Kathryn Alsop, Mariam Mansour, Prudence A Francis, Heather A Thorne, Maria Joao Silva, Nnennaya Kanu, Michelle Dietzen, Andrew Rowan, Maik Kschischo, Stephen Fox, David D Bowtell, Sarah-Jane Dawson, Terence P Speed, Charles Swanton, Sherene Loi

“…Other alterations that could define subclones such as structural variants or epigenetic modifications were not assessed.…”
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STATIC AND DYNAMIC CHARACTERISTIC ANALYSIS AND MULTI-OBJECTIVE TOPOLOGY OPTIMIZATION OF GEARBOX by LIU Wei, ZHU Xiang, GAO Ting, FANG Weidong, LI Hao, CHEN Xuehui, HAO Shuai

“…At the same time，the iterative curves of the optimization results of the three weighting methods were compared to verify the advantages of the combination weighting method.Then, the compromise programming method was used to normalize the sub objectives to obtain the comprehensive objective function.Finally, based on the topology optimization results, stress displacement nephogram，and modal shapes, the box structure was improved.Compared with the original box，the improved box reduces the mass by 11.2%, the maximum stress of the box decreases by 39.6%, the displacement decreases by 5.1%, the node displacement amplitude response decreases by 82.8%, and the all first four-order frequencies increase.The proposed weight allocation method improves the disadvantages of low reliability of sub objective weight value allocation and ignoring subjective judgment, realizes the lightweight of the box. …”
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Defining the functional domain of programmed cell death 10 through its interactions with phosphatidylinositol-3,4,5-trisphosphate. by Christopher F Dibble, Jeremy A Horst, Michael H Malone, Kun Park, Brenda Temple, Holly Cheeseman, Justin R Barbaro, Gary L Johnson, Sompop Bencharit

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Five axis Virtual Machining of Asymmetric Double Cone Expansion Wheel by ZHAO Yan-ling, QIN Sheng, YAN Zhao

“…The structure characteristics, working principle and forming mechanism of the unfolding wheel are analyzed, and the layered cutting point following milling principle is put forward. …”
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INSTITUTE OF MANAGERS OF EDUCATIONAL PROGRAMS OF THE JUDICIARY, IMPROVE THE EFFICIENCY OF SCIENTIFIC RESEARCH AND MANAGEMENT TRAINING (FOR EXAMPLE, SOUTHERN FEDERAL UNIVERSITY) by Tatiana Anopchenko

“…It is undoubted that during an era of development of Internet technologies use of new institutes is a determinant of development of society and therefore in the modern world the tendency to merge of educational structures, integration ofrequirements to quality ofresults of education, formation of the new educational integrated technologies of training takes place. …”
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Occupational Health Risks and HIV Prevention Programming for Informal Extractive Miners in Sub-Saharan Africa: A Narrative Review of Interventions, Challenges, and Lessons Learned by Tafadzwa Dzinamarira, Enos Moyo, Diego F. Cuadros, Helena Herrera, Oscar Mano, Ferris T. Munyonho, Malizgani Mhango, Godfrey Musuka

“…To improve intervention effectiveness and sustainability, stakeholders should focus on community engagement, strengthening health systems, and addressing structural barriers. A multi-sectoral approach is necessary to tackle the broader determinants of health in mining communities.…”
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Improving the robustness of retail workforce management with a labor flexibility strategy and consideration of demand uncertainty by Andrés Felipe Porto, Amaia Lusa, Sebastián A. Herazo, César Augusto Henao

“…To address this problem, a two-stage stochastic optimization model is developed to determine the optimal workforce size, structure a targeted training program using a 2-chaining approach, and allocate weekly working hours, both regular and overtime, while explicitly considering demand variability. …”
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Privacy-preserving ADP for secure tracking control of AVRs against unreliable communication by Kun Zhang, Kezhen Han, Zhijian Hu, Guoqiang Tan

“…Building on a simplified single-network framework, the Hamilton-Jacobi-Bellman equation is approximately solved, avoiding the complexity of dual-network structures and reducing the computational costs. The input-constrained issue is successfully handled using a non-quadratic value function. …”
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A Radiologist's Perspective of Medical Annotations for AI Programs: The Entire Journey from Its Planning to Execution, Challenges Faced by Anuradha Rao

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A systematic review of robotic colorectal surgery programs worldwide and a comprehensive description of local robotic training programme by Valentin Butnari, Harpreet Kaur Sekhon Inderjit Singh, Eshtar Hamid, Shady Gaafar Hosny, Sandeep Kaul, Joseph Huang, Richard Boulton, Nirooshun Rajendran

“…This systematic review aimed to evaluate the structure currently employed worldwide in RACS training programs for colorectal surgery trainees. …”
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Reform Logic and Governance Trends of Teacher Education in High-Level Universities for the "National Excellent Teachers Program" in the New Era by HU Dexin, GUO Hongcong

“…The research shows that the formation of National Excellent Teachers Program has resulted from the complex interplay of multiple factors, including national strategic demands, structural optimization in education, and quality enhancement initiatives. …”
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Perspectives on syringe services programs among patients hospitalized with injection drug use-associated endocarditis: a qualitative study by Bailey McInnes, Eunice A. Okumu, Maisun M. Ansary, Bayla Ostrach, Vivian H. Chu, Li-Tzy Wu, Carol Golin, David L. Rosen, Asher J. Schranz

“…Methods: The research team conducted semi-structured interviews with 16 participants at a large academic hospital from June 2021 to May 2022. …”
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For the security of telecommunication networks on the application program package OPNET Modeler v.14.5 and the use of the «NetDoctor» module by М.З. Якубова, Т.Г. Сериков

“…Detection of used erroneous technologies in the process of building and modeling of telecommunication networks ensures the security of their functioning and predicts their reliable building structure at their design. In our work we use the NetDoctor module of the program package of OPNET Modeler v.14.5 to test the security of the built wireless network. …”
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Complex regulatory network of programmed death-ligand 1 in cancer: Cancer immunomodulation from molecular mechanisms to clinical applications by Yifei Zhang, Keyu Yin, Runsheng Ma, Yuxiao Sun, Longlong Wang, Detao Yin

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Rank revealing‐based tensor completion using improved generalized tensor multi‐rank minimization by Wei Z. Sun, Peng Zhang, Bo Zhao

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Assessment of Artificial Intelligence-Driven Fitness and Health Management Programs for Adolescents Using the SuperHyperSoft Set Framework by Di Wu, Ali Khatibi, Jacquline Tham

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A decision support approach for sustainability management using multiple criteria decision making and statistical techniques by Ana B. Ruiz, Sandra González-Gallardo, Mariano Luque, Pedro M. Fernández-Rodero, Francisco Ruiz

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ITP Adjuster 1.0: A New Utility Program to Adjust Charges in the Topology Files Generated by the PRODRG Server by Diogo de Jesus Medeiros, Wilian Augusto Cortopassi, Tanos Celmar Costa França, André Silva Pimentel

“…Usually additional steps of structure optimization and charges calculation, followed by a tedious manual replacement of atomic charges in the *.itp file, are needed. …”
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AAscan, PCRdesign and MutantChecker: a suite of programs for primer design and sequence analysis for high-throughput scanning mutagenesis. by Dawei Sun, Martin K Ostermaier, Franziska M Heydenreich, Daniel Mayer, Rolf Jaussi, Joerg Standfuss, Dmitry B Veprintsev

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Aligning Public Policy with REPowerEU Program Objectives by Adopting EESS Solutions: A Technology Acceptance Model Approach by Ion Popa, Marian Mihai Cioc, Ștefan Cătălin Popa, Daniel Botez, Marius-Ioan Pantea

“…To validate the research hypotheses, a survey was organised between January and March 2023, and structural equation modelling was used to highlight the effects of the determining factors on adoption intention. …”
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