The extra-islet pancreas supports autoimmunity in human type 1 diabetes by Graham L Barlow, Christian M Schürch, Salil S Bhate, Darci J Phillips, Arabella Young, Shen Dong, Hunter A Martinez, Gernot Kaber, Nadine Nagy, Sasvath Ramachandran, Janet Meng, Eva Korpos, Jeffrey A Bluestone, Garry P Nolan, Paul L Bollyky

“…Finally, we identify lymphoid structures away from islets enriched in CD45RA+ T cells — a population also enriched in one of the inflamed islet sub-states. …”
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Evaluating the Feasibility and Effectiveness of an Interdisciplinary Verbal De-Escalation and Implicit Bias Check Training for Agitation Management in the Emergency Department by Carreras Tartak JA, Rodriguez G, Schwid M, Meeker MA, Thomas MD, Roy HJ, Dadabhoy FZ, Molina M, Chary A, Bukhman AK, Im DD, Temin ES, Macias-Konstantopoulos WL

“…We implemented an interdisciplinary educational program that integrates discussions about the role of bias in physical restraint use with workplace violence (WPV) prevention strategies to increase awareness of implicit bias and comfort with verbal de-escalation among ED staff.Patients and Methods: In partnership with hospital security at a large urban academic medical center, we developed a 1-hour online WPV prerequisite course followed by a 2-hour multi-modal, in-person training consisting of 40 minutes each of didactics, an interactive defensive skills workshop, and case-based simulations with structured debriefings. …”
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Real-world experience with nucleos(t)ide analogue therapy and patient survival rates in chronic viral hepatitis B treatment centers in Eritrea by Michael Berhe Solomon, Ghirmay Ghebrekidan Ghebremeskel, Oliver Okoth Achila, Aron Rezene Mebrahtu, Mohammed Elfatih Hamida, Araia Berhane Mesfin

“…Demographic, clinical, and laboratory information was collected from medical records using a structured checklist. Relevant parametric and nonparametric statistics were employed to explore treatment outcomes and to evaluate differences between groups. …”
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Atividades Físicas de Lazer sistematizadas assíncronas em período de pandemia COVID-19 (Systematized asynchronous physical leisure activities during the COVID-19 pandemic) (Activ... by Junior Vagner Pereira da Silva

“…This manuscript aims to present and describe the planning/preparation and implementation of the offer of Systematized Physical Leisure Activities and asynchronous guidelines during the pandemic. Structured in three phases (diagnosis, elaboration and implementation) it was carried out using Information and Communication Technologies, with asynchronous assistance - video classes. …”
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Analisis Dukungan Petugas Kesehatan Dalam Optimalisasi Competence Baby Care Pada Ibu muda Melalui Pendekatan Maternal Sensitivity Models Berbasis Keluarga (Analysis of Health Of... by diyan indriyani

“…Discussion: It is suggested to the health officials to have more effective and well structured program design in building public perception of baby care, including the training of cadres on an ongoing basis so that the activities of table 5 on Maternal and Child Health services can be improved.   …”
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Analisis Dukungan Petugas Kesehatan Dalam Optimalisasi Competence Baby Care Pada Ibu muda Melalui Pendekatan Maternal Sensitivity Models Berbasis Keluarga (Analysis of Health Of... by diyan indriyani

“…Discussion: It is suggested to the health officials to have more effective and well structured program design in building public perception of baby care, including the training of cadres on an ongoing basis so that the activities of table 5 on Maternal and Child Health services can be improved.   …”
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Modelling POLG mutations in mice unravels a critical role of POLγΒ in regulating phenotypic severity by Samantha Corrà, Alessandro Zuppardo, Sebastian Valenzuela, Louise Jenninger, Raffaele Cerutti, Sirelin Sillamaa, Emily Hoberg, Katarina A. S. Johansson, Urska Rovsnik, Sara Volta, Pedro Silva-Pinheiro, Hannah Davis, Aleksandra Trifunovic, Michal Minczuk, Claes M. Gustafsson, Anu Suomalainen, Massimo Zeviani, Bertil Macao, Xuefeng Zhu, Maria Falkenberg, Carlo Viscomi

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Adaptation, Feasibility, and Acceptability of a Health Insurance Literacy Intervention for Caregivers of Pediatric Cancer Patients (CHAT-C) by Amy Chevrier, Perla L. Vaca Lopez, Katie Rogers, Monique Stefanou, Karely M. van Thiel Berghuijs, Douglas Fair, Elyse R. Park, Anne C. Kirchhoff, Echo L. Warner

“…We conducted engagement studios to adapt the program. Feedback was evaluated using a rapid qualitative analysis framework and included content preferences, navigator preferences, logistics/structure, timing of delivery, and feasibility/acceptability. …”
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International society of liquid biopsy (ISLB) perspective on minimal requirements for ctDNA testing in solid tumors by Nicola Fusco, Konstantinos Venetis, Francesco Pepe, Omshree Shetty, Silvia Calabuig Farinas, Simon Heeke, Julia V. Burnier, Simon J. Patton, Ellen Heitzer, Giovanni Nigita, Paul Hofman, Maria Jose Serrano, Massimo Cristofanilli, Eloisa Jantus-Lewintre, David R. Gandara, Christian Rolfo, Umberto Malapelle

“…Through initiatives led by the Quality Control and Accreditation Committee, educational programs, and multidisciplinary stakeholder workshops, ISLB provides a structured framework to promote standardization and foster innovation. …”
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Quasi Fe MIL-53 nanozyme inducing ferroptosis and immunogenic cell death for cancer immunotherapy by Zihui Yan, Yang Bai, Songtao Zhang, Lingyi Kong, Yu Wang, Huilin Sun, Yi Li, Lin Qiu, Ruijie Zhang, Pengju Jiang, Donghui Zhao, Zhongyan Chen, Yafei Li, Huan Pang, Jianhao Wang

“…Quasi-metal-organic framework is a class of metal-organic framework-derived nanomaterials with a transition state from metal-organic frameworks towards metal oxide featuring porous structure and high activity. Herein an iron-based quasi-metal-organic framework nanozyme Q-MIL-53(Fe) is reported via a controlled deligandation strategy, exhibiting enhanced peroxidase-/catalase-mimic activity and glutathione depletion capacity, whose underlying mechanisms are studied via density functional theory calculations. …”
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The dual role of PGAM5 in inflammation by Yuxin Qi, Bhavana Rajbanshi, Ruihan Hao, Yifan Dang, Churong Xu, Wei Lu, Liming Dai, Bingjun Zhang, Xiaoling Zhang

“…Phosphoglycerate mutase family member 5 (PGAM5) is a novel modulator of mitochondrial homeostasis in response to mechanical stimulation. Here we review the structure and sublocalization of PGAM5, introduce its importance in programmed cell death and summarize its crucial roles in the development and progression of inflammatory diseases such as pneumonia, hepatitis, neuroinflammation and aging. …”
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Cardiac Magnetic Resonance in the Assessment of Atrial Cardiomyopathy and Pulmonary Vein Isolation Planning for Atrial Fibrillation by Nicola Pegoraro, Serena Chiarello, Riccardo Bisi, Giuseppe Muscogiuri, Matteo Bertini, Aldo Carnevale, Melchiore Giganti, Alberto Cossu

“…Advanced imaging techniques, particularly cardiac magnetic resonance (CMR) imaging, have emerged as pivotal in the detailed assessment of atrial structure and function. CMR facilitates the precise measurement of left atrial volume and morphology, which are critical predictors of AF recurrence post-intervention. …”
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Conservation and valorization of Italian potato biodiversity through genotype-by-sequencing (GBS) by M. Martina, R. Natale, R. Natale, E. Vergnano, A. M. Milani, S. Biricolti, L. Andrenelli, E. Portis

“…Genetic diversity was analyzed using genotyping-by-sequencing (GBS), and comparisons were made with a global reference panel of 106 genotypes.ResultsGBS data revealed marked genetic differentiation among the Italian landraces, with three main genetic clusters showing internal structure and minimal overlap with commercial varieties. …”
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MANAJEMEN BOARDING SCHOOL DI SMAIT AL-FITYAN KUBU RAYA DALAM MENINGKATKAN KOMPETENSI PEDAGOGIK GURU by Masrupah Masrupah, Luhur Wicaksono, Tulus Junanto, Usman Radiana, Eni Rosnija

“…Analysis model with data reduction, data presentation and drawing conclusions.The research findings of boarding school management at SMAIT Al-Fityan Kubu Raya in aspect 1) planning show that the annual work plan and financing plan are the implementation of the institution's vision, mission and objectives containing efforts to increase teacher pedagogical competence. 2) The organizational aspect is that the Institution has an organizational structure, a Decree and a schedule of activity programs that describes efforts to increase teacher pedagogical competence. 3) Controlling includes routine monitoring and evaluation activities 4) Reporting aspects in the form of activity and financial reports which are made routinely after activities are completed and submitted to related parties           Keywords: Total Quality Management, School Quality     Abstrak Penelitian ini bertujuan mendeskripsikan fungsi manajemen boarding school pada aspek perencanaan, pengorganisasian, pengawasan dan pelaporan dalam meningkatkan kompetensi pedagogik guru di SMAIT Al-Fityan Kubu Raya. …”
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Promoting effects of campus football activities on the enhancement of adolescents' psychological qualities and the underlying mechanisms by Wanting Zheng, Wenzi Wang, Chenglin Zhou, Chenglin Zhou, Bin Zhang, Bin Zhang

“…The Sport Behavior Scale, Sport Cognitive Level Psychological Assessment Scale, Trait Sport Confidence Scale, and Adolescent Willpower Quality Scale were used to construct a structural equation model. This model revealed the effects of campus football on promoting adolescents' sports behavior, sports cognitive levels, confidence in sports, and willpower qualities, as well as their internal relationships.ResultsSignificant differences in campus football behaviors, sports cognitive levels, sports self-confidence, and willpower qualities existed among adolescents following campus football activities. …”
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Drought Amplifies the Suppressive Effect of Afforestation on Net Primary Productivity in Semi-Arid Ecosystems: A Case Study of the Yellow River Basin by Futao Wang, Ziqi Zhang, Mingxuan Du, Jianzhong Lu, Xiaoling Chen

“…However, mixed forest structural optimization in the Three-North Shelterbelt Forest Program core area achieved local carbon-sink gains, demonstrating that vegetation configuration alleviates water competition pressure. …”
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Barriers to healthcare professionals screening, recognizing, and managing delirium in the adult patients receiving specialist palliative care: a mixed-methods systematic review by Fang Qian, Danyang Yao, Huanhuan Shi, Tao-Hsin Tung, Dongjun Bi

“…Four themes were identified from the includes studies: (1) Individual level: knowledge and understanding gaps among healthcare professionals; (2) Operational level: implementation challenges in clinical practice; (3) Organizational level: structural and resource deficiencies; (4) Contextual level: specific impacts of situational factors. …”
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Psychological health and safety of criminal justice workers: a scoping review of strategies and supporting research by Christopher Canning, Tyler Szusecki, N. Zoe Hilton, Elnaz Moghimi, Ashley Melvin, Matthew Duquette, Jolene Wintermute, Nicole Adams

“…Fewer records discussed the need to address structural and policy considerations such as labor shortages, patchy mental health benefits, underfunding, and discrimination. …”
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Genomic and proteomic characterization of four novel Schitoviridae family phages targeting uropathogenic Escherichia coli strain by Hira Niaz, Mikael Skurnik, Fazal Adnan

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Assessment of Risk Factors of Chronic Kidney Disease among Patients Attending Medical City Complex by Nabaa Wisam Sabri, Buthaina Ateyah Rashid, Raheem Saber Shwiehk, Azad H. Mahdy

“… Chronic kidney disease is a worldwide health problem that is defined as structural abnormalities or progressive or permanent loss of renal function for 3 months or more, which is usually associated with a decrease in glomerular filtration rate (GFR) of less than 60 mL/min/1.73 m2 or persistent proteinuria, which can lead to end-stage renal disease (ESRD) or kidney failure. …”
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