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17041
Association between hemoglobin glycation index and the risk of cardiovascular disease in early-stage cardiovascular-kidney-metabolic syndrome: evidence from the China health and re...
Published 2025-05-01“…Additionally, the SHAP plot revealed that HGI were the more important features than traditional risk factors such as FBG for predicting CVD.ConclusionHGI is associated with an elevated risk of CVD in participants with early-stage CKM syndrome. …”
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17042
Machine-learning assisted discovery unveils novel interplay between gut microbiota and host metabolic disturbance in diabetic kidney disease
Published 2025-12-01“…Finally, the predicted functional capability of a DKD-specific biomarker, Gemmiger spp. is enriched in carbohydrate metabolism and branched-chain amino acid (BCAA) biosynthesis. …”
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17043
Multiplicity dependence of charged-particle intra-jet properties in pp collisions at $$\sqrt{{{\varvec{s}}}}$$ s = 13 TeV
Published 2024-10-01“…The results are compared with predictions of QCD-inspired event generators, PYTHIA 8 with Monash 2013 tune and EPOS LHC. …”
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17044
High-Resolution Mapping of Litter and Duff Fuel Loads Using Multispectral Data and Random Forest Modeling
Published 2024-11-01“…The results revealed moderate determination coefficients between observed and predicted fuel loads with R<sup>2</sup> = 0.32, RMSE = 0.53 Mg/ha for litter and R<sup>2</sup> = 0.38, RMSE = 13.14 Mg/ha for duff fuel loads, both with significant <i>p</i>-values of 0.018 and 0.015 for litter and duff fuel loads, respectively. …”
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17045
A Multi-Omics Prognostic Model Capturing Tumor Stemness and the Immune Microenvironment in Clear Cell Renal Cell Carcinoma
Published 2024-09-01“…Recognizing tumor stemness helps to predict treatment efficacy, recurrence, and drug resistance, informing treatment strategies and enhancing ccRCC patient outcomes.…”
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17046
Strategic optimization of engine performance and emissions with bio-hydrogenated diesel and biodiesel: A RVEA-GRNNs framework
Published 2024-12-01“…The Generalized Regression Neural Networks model demonstrated high accuracy in predicting engine performance and emissions, with coefficient of determination (R2) values exceeding 0.98 and mean absolute percentage errors below 5 %. …”
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17047
Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity
Published 2025-01-01“…Here we use SolubiS and dTANGO, computational algorithm-based methods, to predict mutations within the IL2 structure to improve protein production yield in muteins with altered cellular selectivity, to generate combined muteins with elevated therapeutic potential. …”
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17048
Multi-omics analyses of the heterogenous immune microenvironment in triple-negative breast cancer implicate UQCRFS1 potentiates tumor progression
Published 2025-06-01“…Particularly, IL32high Treg imparted an essential effect on tumor evasion and predicted a worsened prognosis of TNBC patients. Furthermore, MCI model enabled to notify the inferior prognosis and immunotherapy resistance in TNBC. …”
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17049
A cloud-metaheuristic-based framework for stochastic optimization of a hybrid wind/hydrogen based-Fuel cell system in distribution network considering uncertainty
Published 2025-08-01“…An improved Fire Hawks Optimization (IFHO) algorithm is utilized in solving the optimization problem by determining the optimal installation locations and sizes of HRES components. …”
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17050
Preliminary evaluation of ShallowHRD performance compared to HRDetect in familial breast cancer tumors
Published 2025-08-01“…Abstract Determining the Homologous Recombination Deficiency (HRD)-status of a malignant tumor is central in predicting patient response to specific treatments. …”
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17051
Serum Lipid Biomarkers for the Diagnosis and Monitoring of Neuromyelitis Optica Spectrum Disorder: Towards Improved Clinical Management
Published 2025-03-01“…Additionally, a combination of these lipid biomarkers was found to predict relapse with the AUC of 0.861. A user-friendly smartphone application was developed to facilitate the straightforward “input-index, output-answer” screening process, enhancing both clinical decision-making and patient care.Conclusion: The diagnostic model based on the serum lipid-related indexes (TC, TG, LDL, HDL, ApoA1, and ApoB) may be the useful tool for NMOSD in diagnosis and monitoring of disease stage, thereby improving the treatment outcome for patients. …”
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17052
Experimental Study on Compressive Capacity Behavior of Helical Anchors in Aeolian Sand and Optimization of Design Methods
Published 2025-07-01“…The compressive capacity of helical anchors constitutes a pivotal performance parameter in geotechnical design. To precisely predict the compressive bearing behavior of helical anchors in aeolian sand, this study integrates in situ testing with finite element numerical analysis to systematically elucidate the non-linear evolution of its load-bearing mechanisms. …”
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17053
Immunotyping of thyroid cancer for clinical outcomes and implications
Published 2025-05-01“…Furthermore, the prognostic model’s utility in predicting immunotherapy response was analyzed. The potential therapeutic drugs were obtained. …”
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17054
Simplification of the diagnostic approach and treatment of Hepatitis C Virus.
Published 2025-04-01“…Fibrosis was calculated using the APRI algorithm, finding 53/130 with >1.5 and 60/130 with >3.25, which predicted F3-4. …”
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17055
Potential Metabolic Markers in the Tongue Coating of Chronic Gastritis Patients for Distinguishing Between Cold Dampness Pattern and Damp Heat Pattern in Traditional Chinese Medici...
Published 2025-07-01“…The model quality was evaluated by 7-fold cross-validation, and the model validity was evaluated based on R²Y (interpretability of categorical variable Y) and Q² (predictability of the model), and the permutation test was used for further verification. …”
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17056
Novel computational One-Health analysis of fibrinogen-binding protein A in Streptococcus agalactiae Isolated from fish and human cases
Published 2025-05-01“…Three-dimensional structures were predicted through ColabFold and validated using Ramachandran plots. …”
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17057
Klasifikasi Kinerja Akademik Siswa Menggunakan Neighbor Weighted K-Nearest Neighbor dengan Seleksi Fitur Information Gain
Published 2022-06-01“…Neighbor Weighted K-Nearest Neighbor algorithm with Information Gain method will be applied to this study to help predict student performance. …”
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17058
Development of policy research-evidence organizer and public health-policy evaluation tool (prophet): a computing paradigm for promoting evidence-informed policymaking in Nigeria
Published 2024-12-01“…It strategically evaluates and assess level of evidence content, and predict implementation prospects of health policy documents.…”
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17059
Loneliness, insomnia symptoms, social jetlag, and vitamin D deficiency in relation to mental health problems in Japanese female university students: a cross-sectional study
Published 2025-07-01“…Loneliness was assessed using the Three-Item Loneliness Scale. Factors predicting mental health problems with a K6 score ≥ 5 were explored using the Mann–Whitney U test, Fisher’s exact probability test, and classification and regression tree (CART) analysis. …”
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17060
Clinical portrait of an "ordinary" patient with benign prostatic hyperplasia and the efficacy of treating lower urinary tract symptoms
Published 2023-04-01“…Indicators of IPSS, Q max and PVR after 3 months of therapy allow predicting the effectiveness of therapy, or suspect the need for surgical treatment.…”
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