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15121
Phenotyping sarcoidosis: a single institution retrospective analysis
Published 2025-05-01“…For instance, finding a relationship between symptom burden, race, gender, HRQoL, and pulmonary function could have therapeutic ramifications, influence clinical practice, and aid in selecting patients for specific clinical studies.MethodsA comprehensive statistical evaluation was conducted using the JMP partitioning algorithm which explores all potential divisions to identify the most predictive variables.ResultsWith our analysis, we tried to categorize patients from a single Institution respiratory unit to delineate clinical phenotypes in sarcoidosis.ConclusionsLarger studies using appropriate methodology should surely be carried out to address this issue and help clarify the varying contributions of genetics, socioeconomic status, environmental exposures, and other sociodemographic factors to illness severity and phenotypic presentation. …”
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15122
Preoperative imaging and intraoperative navigation of the parathyroid glands neoplasms in primary hyperparathyroidism
Published 2022-02-01“…The results allowed us to develop an algorithm for preoperative topical diagnosis of parathyroid glands in patients with laboratory-verified primary hyperparathyroidism and indications for surgical treatmen. …”
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15123
SAHVAI‐3D and 4D: Automated AI Volumetric Measurement of Subarachnoid Hemorrhage on Noncontrast Head CT
Published 2025-05-01“…The SAHVAI deep learning algorithm generated automated SAHV values in cubic centimeters. …”
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15124
Combining Super-Resolution Imaging and Shear Wave Elastography for Enhanced Risk Assessment of Moderate-to-Severe Renal Fibrosis in Chronic Kidney Disease Patients
Published 2025-06-01“…Furthermore, the nomogram, which integrated clinical factors and ultrasound composite parameters, exhibited excellent predictive performance (AUC = 0.878, 95% CI 0.782– 0.974). …”
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15125
Clinical characteristics of COVID-19 in children and adolescents: insights from an Italian paediatric cohort using a machine-learning approach
Published 2025-06-01“…First, we apply an unsupervised machine-learning algorithm to cluster individuals into groups. Second, we classify new patient risk groups using a random forest classifier model based on sociodemographic information, pre-existing medical conditions, vaccination status and the VOC as predictive variables. …”
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15126
Neuromorphic, physics-informed spiking neural network for molecular dynamics
Published 2025-01-01“…The results indicate that NP-SNN provides a robust Sci-ML framework that can make accurate predictions across diverse scientific molecular applications. …”
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15127
Pilot Protection of New Energy Transmission Line in Active Distribution Network Based on 5G Communication
Published 2024-11-01“…Traditional pilot differential protection will have the problem of reliability reduction or even failure to operate after the access of new energy stations. …”
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15128
Development of an interpretable model for foot soft tissue stiffness based on gait plantar pressure analysis
Published 2025-01-01“…A backpropagation neural network, optimized by integrating particle swarm optimization and genetic algorithm, was constructed to predict foot soft tissue stiffness using plantar pressure data collected during walking. …”
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15129
Improved Smart Power Socket for Monitoring and Controlling Electrical Home Appliances
Published 2018-01-01“…A 24-min implementation of the proposed energy management algorithm shows a reduction of 0.811 kWmin (0.0134 kWh) in energy usage after the use of the smart sockets as load controllers. …”
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15130
Identification of water sources of mine water bursts based on the FPS-DT model
Published 2025-07-01“…The fuzzy C-means (FCM) clustering method is employed to classify water sample data, followed by principal component analysis (PCA) for dimensionality reduction to extract key features. The SMOTE algorithm is then applied to address the issue of class imbalance. …”
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15131
Improved UAV Target Detection Model for RT-DETR
Published 2025-01-01“…In light of the shortcomings pertaining to UAV small target detection, the detection of complex scenes, and the detection of multi-scale targets, a time-frequency dual-domain feature extraction algorithm, TF-DETR, has been proposed. This algorithm has been optimized for RT-DETR.Firstly, a time-frequency domain feature extraction module, TF-CSPNet, has been introduced into the backbone network. …”
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15132
In-Silico discovery of novel cephalosporin antibiotic conformers via ligand-based pharmacophore modelling and de novo molecular design
Published 2025-09-01“…This research aims to predict new compounds using ligand-based pharmacophore models while optimizing existing drugs. …”
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15133
DEPDC1B, CDCA2, APOBEC3B, and TYMS are potential hub genes and therapeutic targets for diagnosing dialysis patients with heart failure
Published 2025-01-01“…We constructed a ceRNA regulatory network, and found that 4 hub genes (TYMS, CDCA2 and DEPDC1B) might be regulated by 4 miRNAs (hsa-miR-1297, hsa-miR-4465, hsa-miR-27a-3p, hsa-miR-129-5p) and 21 lncRNAs (such as HCP5, CAS5, MEG3, HCG18). 24 small molecule drugs were predicted based on TYMS through DrugBank website. Finally, qRT-PCR experiments showed that the expression trend of biomarkers was consistent with the results of transcriptome sequencing.DiscussionOverall, our results reveal the molecular mechanism of HF in patients with MHD and provide insights into potential diagnostic markers and therapeutic targets.…”
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15134
Optimal vaccination model of airborne infection under variable humidity and demographic heterogeneity for hybrid fractional operator technique
Published 2025-04-01“…Our system’s best-fit parameter settings were detected using the Markov Chain Monte Carlo (M-C-M-C) technique with influenza information collected in Spain. We predict a basic reproduction number of 1.3645 (96% C.I: (1.3644, 1.3646)). …”
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15135
At-Home Evaluation of Both Wearable and Touchless Digital Health Technologies for Measuring Nocturnal Scratching in Atopic Dermatitis: Analytical Validation Study
Published 2025-07-01“…Within-night agreement of DHT-predicted scratching events versus the Reference was assessed by sensitivity, precision, and F1 ResultsCharacterization of human-annotated scratching revealed a basal level of scratching in both healthy volunteers (13.1 seconds per hour) and in participants with AD on nights when no itch was reported (10.2 seconds per hour). …”
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15136
Bioinformatics‑Based Analysis Reveals Diagnostic Biomarkers and Immune Landscape in Atopic Dermatitis
Published 2025-05-01“…Potential microRNA (miRNA)-messenger RNA (mRNA) and miRNA-long non-coding RNA (lncRNA) interactions were predicted using miRanda and TargetScan tools.Results: We identified 381 DEGs (217 upregulated, 164 downregulated). …”
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15137
The underlying molecular mechanisms and biomarkers of Hip fracture combined with deep vein thrombosis based on self sequencing bioinformatics analysis
Published 2025-05-01“…Conclusions In conclusion, five feature genes (RGS1, HSF2, ARL4A, AAED1, and WDR81) were identified, and functional enrichment analyses were conducted, providing a foundation for predicting the diagnosis of fractures associated with thrombosis.…”
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15138
Single cell transcriptomic analysis reveals tumor immune infiltration by macrophage cells gene signature in lung adenocarcinoma
Published 2025-03-01“…High TGS tumors exhibited enrichment in TGF-β signaling and hypoxia pathways, suggesting their potential utility in predicting prognosis and immune responses in patients with LUAD. …”
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15139
Identifying mating events of group-housed broiler breeders via bio-inspired deep learning models
Published 2025-07-01“…The DLM framework included a bird detection model, data filtering algorithms based on mating duration, and logic frameworks for mating identification based on bird count changes. …”
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15140
Comparative performance evaluation of quartz and snail shell powders modified concrete: Mechanical, machine learning, and microstructural assessments
Published 2025-05-01“…Later, the extreme gradient boosting ML algorithm provided a nominal coefficient of determination of 0.988 in the prediction of compressive strength of concrete compared to the gradient boosting and random forest model. …”
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