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Immune Evasion Mechanism Mediated by ITPRIPL1 and Its Prognostic Implications in Glioma
Published 2025-08-01“…Ninety‐eight machine learning algorithm combinations were screened to identify the optimal predictive model. …”
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Association of estimated glucose disposal rate with atrial fibrillation, heart failure and cardiovascular mortality in patients with diabetes: a prospective cohort study from the U...
Published 2025-07-01“…Polygenic Risk Score (PRS) analysis evaluated the joint effects of eGDR and PRS. Boruta algorithm filtered key predictive variables. Subgroup analysis was performed using cardiovascular high-risk factors, and mediation analysis explored the relationships of eGDR with the outcomes.ResultsSubjects with higher eGDR were more likely to be female, younger, more physically active, non-smoker, and non-drinker. …”
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PDT-regulated immune gene prognostic model reveals tumor microenvironment in colorectal cancer liver metastases
Published 2025-04-01“…Subsequently, utilizing single-cell sequencing data about liver metastasis, the colorectal cancer immune microenvironment reflected in the predictive model was analyzed, and a key gene set of the model was identified. …”
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Type 1 diabetes prevention clinical trial simulator: Case reports of model‐informed drug development tool
Published 2024-08-01“…Using individual‐level data collected from the TrialNet Pathway to Prevention and The Environmental Determinants of Diabetes in the Young natural history studies, we previously developed a quantitative joint model to predict the time to T1D onset. We then applied trial‐specific inclusion/exclusion criteria, sample sizes in treatment and placebo arms, trial duration, assessment interval, and dropout rate. …”
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Multimodal identification of a rare head and neck cancer patient cohort in the clinical data warehouse of Greater Paris Teaching Hospital
Published 2025-06-01“…It showed a 91% sensitivity and a 95% specificity when relying on multiple data sources, with a 76% positive predictive value observed for rare histology identification compared with 43% for rare topography. …”
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Scalable Precision Psychiatry With an Objective Measure of Psychological Stress: Prospective Real-World Study
Published 2025-07-01“…Algorithm predictions were compared against the efficacy of the individual’s self-selected sessions. …”
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Machine learning-driven design of rare metal doped niobium alloys with enhanced strength and ductility
Published 2025-05-01“…A comprehensive database of niobium alloys' properties was analyzed using feature engineering, and a high-accuracy prediction model, Gray Wolf Optimization-Extreme Learning Machine (GWO-ELM), was constructed, achieving R2 values of 0.95 and 0.88 for tensile strength and elongation, respectively. …”
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Deep learning-based framework for Mycobacterium tuberculosis bacterial growth detection for antimicrobial susceptibility testing
Published 2025-01-01“…Using 4,018 plate images from the CRyPTIC (Comprehensive Resistance Prediction for Tuberculosis: An International Consortium) dataset to train models and refine the framework, TMAS achieved an essential agreement of 98.8%, significantly outperformed the 90% threshold established by the International Organization for Standardization (ISO). …”
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AI-Powered Identification of Osteoporosis in Dental Panoramic Radiographs: Addressing Methodological Flaws in Current Research
Published 2024-10-01“…Initially, the YOLOv8 object detection model was employed to predict the regions of interest. Subsequently, the predicted regions of interest were extracted from the PRs and processed by the EfficientNet classification model. …”
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Analysis of the molecular nature associated with microsatellite status in colon cancer identifies clinical implications for immunotherapy
Published 2020-10-01“…A more homogeneous highly expressed pattern of PD1 was observed in CD8+ T cells from MSI colon cancer; however, a small subgroup of CD8+ T cells with high expression of checkpoint molecules was identified in MSS patients. A random forest algorithm predicted important mutations that were associated with MSI status in the TCGA colon cancer cohort, and our in-house cohort validated higher frequencies of BRAF, ARID1A, RNF43, and KM2B mutations in MSI colon cancer. …”
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Enhancing personalized learning: AI-driven identification of learning styles and content modification strategies
Published 2024-01-01“…In the rapidly advancing era of educational technology, customized learning materials have the potential to enhance individuals’ learning capacities. …”
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CECT-Based Radiomic Nomogram of Different Machine Learning Models for Differentiating Malignant and Benign Solid-Containing Renal Masses
Published 2025-01-01“…Among the various radiomic models, the LR model demonstrated superior predictive efficiency and robustness, yielding an AUC of 0.952 in the training cohort and 0.887 in the test cohort. …”
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Deciphering the heterogeneity of epithelial cells in pancreatic ductal adenocarcinoma: implications for metastasis and immune evasion
Published 2025-04-01“…A prognostic model incorporating five key genes, including KLF6, was developed and demonstrated strong predictive accuracy for patient outcomes. Notably, KLF6 emerged as a critical prognostic marker associated with immune modulation, particularly through interactions with M2 macrophages. …”
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Dehydrotanshinone II A alleviates osteoarthritis via activating PPARγ to inhibit ferroptosis in chondrocytes
Published 2025-08-01“…Bioinformatics analysis identified five key genes (CDKN1A, HMOX1, DPP4, GJA1, and PPARγ), among which PPARγ and HMOX1 exhibited strong predictive potential with AUC values > 0.8. Molecular docking analysis revealed that DHT IIA exhibited the lowest binding energy with PPARγ (-8.15 kcal/mol), indicating it as the most likely therapeutic target. …”
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Association Between Social Distancing Compliance and Public Place Crowding During the COVID-19 Pandemic: Cross-Sectional Observational Study Using Computer Vision to Analyze Survei...
Published 2025-04-01“…We automatized the analysis of this footage using a computer vision algorithm designed for pedestrian detection and estimation of metric distances between individuals in the video still frames. …”
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The Social Construction of Categorical Data: Mixed Methods Approach to Assessing Data Features in Publicly Available Datasets
Published 2025-01-01“…ResultsOur quantitative study suggests scattered effects of including categorical data for machine learning model training across predictive classes. Our qualitative analysis gives insights into how the categorical data were collected and why they were published, explaining some of the quantitative effects that we observed. …”
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Projecting Forest Fire Probability in South Korea Under Climate Change, Population, and Forest Management Scenarios Using AI & Process-Based Hybrid Model (FLAM-Net)
Published 2025-01-01“…Enhancements included improving backpropagation for optimization and introducing algorithms for national-specific fire ignition dynamics. …”
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