Novel Insights from Comprehensive Bioinformatics Analysis Utilizing Large-Scale Human Transcriptomes and Experimental Validation: The Role of Autophagy in Periodontitis by Liu F, Zhu Z, Zou H, Huang Z, Xiao S, Li Z

“…Subsequently, a comprehensive analysis of immune cell infiltrate utilizing the CIBERSORT algorithm was performed. Finally, leveraging the DSigDB database, potential candidate drugs for periodontitis treatment targeting autophagy were predicted.Results: A total of 79 genes have been identified as DEARGs in periodontitis. …”
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Utility of positron emission tomography–computed tomography in the evaluation of fever of unknown origin in a resource-limited tropical nation by Sohini Das, Sowmya Sathyendra, Julie Hephzibah, Reka Karuppusami, Karthik Gunasekaran, Nylla Shanthly, Angel Miraclin, Ramya Iyadurai

“…We also looked at laboratory parameters as predictors of contributory PET-CT scans and propose an algorithm for evaluation of FUO in resource-limited tropical regions. …”
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Relationship Between Sepsis Phenotypes and Treatment Characteristics of Patients with Viral and Bacterial Pneumonia by I. A. Ruslyakova, E. Z. Shamsutdinova, L. B. Gaikovaya

“…Sepsis phenotypes were identified using algorithm proposed by Seymour C.W. et al. In SCAP cases associated with COVID-19 infection (n=293, 51.6%) patients received genetically engineered biological therapy (GIBT). …”
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Immunogenic cell death-related genes as prognostic biomarkers and therapeutic insights in uterine corpus endometrial carcinoma: an integrative bioinformatics analysis by Tianfei Yi, Zhenglun Yang, Peng Shen, Yan Huang

“…The immune landscape was characterized through multiple bioinformatics approaches, and immunotherapy response was predicted using the Tumor Immune Dysfunction and Exclusion (TIDE) algorithm. …”
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Single-cell and bulk transcriptome analyses reveal elevated amino acid metabolism promoting tumor-directed immune evasion in colorectal cancer by Tianyue Sun, Yan Chen, Ying-Xuan Chen

“…Additionally, LASSO and Cox regression analyses were conducted to construct an AA metabolism-related risk score for predicting prognosis and drug sensitivity across multiple bulk transcriptome cohorts.ResultsThis study identified a link between elevated amino acid metabolism in CRC epithelial cells and resistance to PD-1 blockade therapy. …”
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Comparative Analysis of Single‐ and Dual‐Marker Strategies for Rapid Non–ST‐Segment–Elevation Myocardial Infarction Rule‐Out Using Cardiac Myosin‐Binding Protein C, Copeptin, and H... by Mustafa Yildirim, Christian Salbach, Matthias Mueller‐Hennessen, Norbert Frey, Evangelos Giannitsis

“…DMS protocols showed negative predictive values of 99.1% to 100%, comparable with the European Society of Cardiology algorithms (99.3%–100%). …”
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An explainable GeoAI approach for the multimodal analysis of urban human dynamics: a case study for the COVID-19 pandemic in Rio de Janeiro by David Hanny, Dorian Arifi, Steffen Knoblauch, Bernd Resch, Sven Lautenbach, Alexander Zipf, Antonio Augusto de Aragão Rocha

“…We introduce a feature selection algorithm based on Chatterjee’s Xi measure of dependence to identify relevant features on an Área Programática da Saúde (health area) and city-wide level. …”
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Simulation and Modelling of C+L+S Multiband Optical Transmission for the OCATA Time Domain Digital Twin by Prasunika Khare, Nelson Costa, Marc Ruiz, Antonio Napoli, Jaume Comellas, Joao Pedro, Luis Velasco

“…In view of that, the fourth-order Runge–Kutta in the interaction picture (RK4IP) method, complemented with an adaptive step size algorithm to further reduce the computation time, is evaluated as an alternative to reduce time complexity. …”
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Interpretable machine learning for depression recognition with spatiotemporal gait features among older adults: a cross-sectional study in Xiamen, China by Shaowu Lin, Sicheng Li, Ya Fang

“…The developed machine learning models with high predictive accuracy, suggest the potential of Kinect-based gait assessment as a real-time and cost-effective screening tool for older adults with depressive symptoms.…”
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Artificial Intelligence ECG Diastolic Dysfunction and Survival in Cardiac Intensive Care Unit Patients by Jacob C. Jentzer, Eunjung Lee, Zachi Attia, Dustin Hillerson, Garvan C. Kane, Francisco Lopez‐Jimenez, Peter A. Noseworthy, Paul A. Friedman, Jae K. Oh

“…An artificial intelligence enhanced ECG (AIECG) algorithm can predict LVDD and mortality in general populations but has not been examined in cardiac intensive care units. …”
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Market and cadastral data comparison for the real estate market value forecasting by M. B. Laskin, P. A. Cherkesova

“…The theoretical significance of the work is the proposed algorithm for estimating the most probable trajectory of the market value of the investigated object, based on the conditional multivariate log-normal distribution for a given value of the cadastral value. …”
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Stepwise autonomous orbit determination of large LEO constellations by GNSS observations with partial inter-satellite ranging by Yuanxi Yang, Xiaoyong Song

“…The difference of the adaptive stepwise OD algorithm is that the covariance matrix of the predicted orbit parameters based on the dynamic model is modified by an adaptive factor. …”
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Artificial intelligence based surgical support for experimental laparoscopic Nissen fundoplication by Holger Till, Ciro Esposito, Chung Kwong Yeung, Dariusz Patkowski, Sameh Shehata, Steve Rothenberg, Georg Singer, Tristan Till

“…For 3/5 classifiers the results remained identical; detection of incomplete and too loose LNFs showed a slight decline in predictive power.ConclusionThis experimental study demonstrates that an AI/CV algorithm can effectively detect VQIs in digital images of Nissen fundoplications. …”
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Research on Non-Random Vibration Analysis of Concrete Pump Truck Boom Based on Dynamic Excitation by Weixin Zhou, Wubin Xu, Bing Li, Yuanbin Xiao, Xianyu Liu, Hanwen Zhang, Bo Xu

“…The technique can reliably predict the dynamic displacement boundary and control the casting position deviation within a predefined range by accurately predicting the dynamic displacement range of the pump truck’s boom end and efficiently constructing the displacement envelope under uncertain dynamic excitation. …”
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Full-chain comprehensive assessment and multi-scenario simulation of geological disaster vulnerability based on the VSD framework: a case study of Yunnan province in China by Li Xu, Shucheng Tan, Runyang Li

“…Thus, scientifically assessing and predicting geological disasters and formulating disaster prevention and mitigation policies are of critical importance for promoting regional sustainable development. …”
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Multi-objective optimization of sustainable cement-zeolite improved sand based on life cycle assessment and artificial intelligence [version 1; peer review: 1 approved, 2 approved... by Hossein MolaAbasi, Satinder Kaur Brar, Amin Tanhadoust, Sepideh Nasrollahpour, Omolbanin Ataee, Moncef L. Nehdi

“…This study proposes a multi-objective optimization approach using back-propagation neural network (BPNN) to predict the mechanical strength, along with an adaptive geometry estimation-based multi-objective evolutionary algorithm (AGE-MOEA) to identify the best parameters for cement-zeolite-improved sand, filling a long-lasting research gap. …”
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A novel mitochondrial quality regulation gene signature for anticipating prognosis, TME, and therapeutic response in LUAD by multi-omics analysis and experimental verification by Lijun Zeng, Sixuan Wu, Zhimin Li, Yuanbin Tang, Yeru Tan, Renji Liang, Yuehua Li

“…Utilizing the LASSO algorithm and multivariate COX regression, a predictive risk model was created. …”
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Increasing Systemic Resilience to Socioeconomic Challenges: Modeling the Dynamics of Liquidity Flows and Systemic Risks Using Navier–Stokes Equations by Davit Gondauri, Nino Chedia, Vakhtang Tsintsadze

“…The methodology is based on a mixed approach: econometric testing, Fourier analysis, stochastic simulations, and AI-algorithm tuning, which together provide dynamic testing, calibration, and forecasting capabilities of the model. …”
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Risk analysis of the association between EASIX and all-cause mortality in critical ill patients with atrial fibrillation: a retrospective study from MIMIC-IV database by Yu Xia, Anfeng Liang, Mei Wang, Jianlin Zhang

“…EASIX was calculated as lactate dehydrogenase (U/L) × creatinine (mg/dL)/platelets (109 cells/L) and log2-transformed for statistical analysis. The Boruta algorithm and Least Absolute Shrinkage and Selection Operator (Lasso) Regression were used for feature selection. …”
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Cer(d18:1/16:0) as a biomarkers for acute coronary syndrome in Chinese populations by Liang Zhang, Yang Zhang, YaoDong Ding, Tong Jin, Yi Song, Lin Li, XiaoFang Wang, Yong Zeng

“…Diagnostic performance assessments showed that Cer(d18:1/16:0) had superior accuracy in detecting ACS compared to other ceramides tested. The Boruta algorithm identified 8 significant variables related to ACS. …”
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