A Clinically Interpretable Approach for Early Detection of Autism Using Machine Learning With Explainable AI by Oishi Jyoti, Hafsa Binte Kibria, Zareen Tasnim Pear, Md Nahiduzzaman, Md. Faysal Ahamed, Khandaker Reajul Islam, Jaya Kumar, Muhammad E. H. Chowdhury

“…Three different publicly available datasets have been used based on the age group to create the best predicting model for each case. After handling missing values, balancing the dataset, and analyzing the classifier’s performance, it is found that tree-based algorithms, particularly RF, perform better for all the datasets. …”
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Evaluation of the shielding initiative in Wales (EVITE Immunity): protocol for a quasiexperimental study by Stephen Jolles, Ashley Akbari, Andrew Carson-Stevens, Helen Snooks, Alan Watkins, Adrian Edwards, Ann John, Alison Porter, Victoria Williams, Bridie Angela Evans, Ronan Lyons, Bernadette Sewell, Mark Rhys Kingston, Tony Whiffen, Jane Lyons, Rowena Bailey, Catherine A Thornton, Lesley Bethell, Samantha Bufton, Lucy Dixon

“…Introduction Shielding aimed to protect those predicted to be at highest risk from COVID-19 and was uniquely implemented in the UK during the COVID-19 pandemic. …”
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Artificial Intelligence–Enabled ECG Screening for LVSD in LBBB by Hak Seung Lee, MD, Sooyeon Lee, MD, Sora Kang, MS, Ga In Han, MS, Ah-Hyun Yoo, MS, Jong-Hwan Jang, PhD, Yong-Yeon Jo, PhD, Jeong Min Son, MD, Min Sung Lee, MD, MS, Joon-myoung Kwon, MD, MS, Kyung-Hee Kim, MD, PhD

“…Conclusions: Our findings indicate that a broad AI-ECG model reliably detects LVSD in LBBB patients, and transfer learning offers modest improvements without requiring curated LBBB data sets. Evaluating algorithms in representative clinical populations is essential.…”
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Causes of embryo implantation failure: A systematic review and metaanalysis of procedures to increase embryo implantation potential by Francesco M. Bulletti, Romualdo Sciorio, Alessandro Conforti, Roberto De Luca, Carlo Bulletti, Antonio Palagiano, Marco Berrettini, Giulia Scaravelli, Roger A. Pierson

“…Subsequent studies ought to concentrate on modulating endometrial responses immunologically and developing algorithms to improve the precision of predicting implantation success; as well as the timing of endometrial receptivity and the occurrence of dormant embryo phenomena also warrants further investigation.…”
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Comprehensive profiling of chemokine and NETosis-associated genes in sarcopenia: construction of a machine learning-based diagnostic nomogram by Yingwei Wang, Le Wang, Yan Zhang, Minghui Wang, Huaying Zhao, Cheng Huang, Huaiyang Cai, Shuangyang Mo

“…Two machine learning algorithms and univariate analysis were integrated to screen signature genes, which were subsequently used to construct diagnostic nomogram models for sarcopenia. …”
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Investigating Transcriptional Age Acceleration in Inflammatory Skin Diseases by Richie Jeremian, Melissa Galati, Rayyan Fotovati, Kaiyang Li, Carolyn Jack, David O. Croitoru, Stephan Caucheteux, Philippe Lefrançois, Vincent Piguet

“…We investigated the role of transcriptional clocks in patients with hidradenitis suppurativa (n = 37), those with atopic dermatitis (n = 27), those with plaque psoriasis (n = 28), and healthy subjects (n = 38) using 7 clock algorithms, to improve the understanding of underlying pathophysiology and disease trajectory. …”
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Pre-treatment tumour PET metrics and clinical outcomes of anal cancer in patients living with and without HIV by Michael Pennock, N. Patrik Brodin, Christian Velten, Megi Gjini, Nitin Ohri, Chandan Guha, Shalom Kalnicki, Wolfgang A. Tome, Madhur K. Garg, Rafi Kabarriti

“…Pre-treatment PET metrics were validated as significantly predicting outcomes for the entire cohort and HIV-negative patients, not PLWH. …”
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Bioinformatics analysis of comorbid mechanisms between ischemic stroke and end stage renal disease by Shuhong Wang, Zhongda Li, Xiao Wang, Jiexue Zhou, Shandong Meng, Jinyang Zhuang, Yan Zhou, Qin Zhao, Chunli Zhu, Yusheng Zhang, Sheng Shen

“…Protein-protein interaction networks were constructed using STRING with clustering algorithms. Immune cell infiltration analysis was performed via CIBERSORT. …”
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Enhancing ovarian cancer prognosis with an artificial intelligence-derived model: Multi-omics integration and therapeutic implications by You Wu, Kunyu Wang, Yan Song, Bin Li

“…Results: The AIDPI model demonstrated superior accuracy in predicting ovarian cancer prognosis compared to existing models. …”
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Classification of SERS spectra for agrochemical detection using a neural network with engineered features by Mateo Frausto-Avila, Monserrat Ochoa-Elias, Jose Pablo Manriquez-Amavizca, María del Carmen González-López, Gonzalo Ramírez-García, Mario Alan Quiroz-Juárez

“…Compared to other machine-learning algorithms, our approach offers reduced computational complexity while maintaining or exceeding the accuracy of more complex models. …”
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Structural and social determinants of health: The multi-ethnic study of atherosclerosis. by Lilah M Besser, Sarah N Forrester, Milla Arabadjian, Michael P Bancks, Margaret Culkin, Kathleen M Hayden, Elaine T Le, Isabelle Pierre-Louis, Jana A Hirsch

“…Forty-seven (11%) of the papers combined MESA with other cohorts for cross-cohort comparisons and replication/validation (e.g., validating algorithms).<h4>Conclusions</h4>Overall, MESA has made significant contributions to the field and the published literature, with 20% of its published papers focused on SSDOH. …”
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Machine learning for epithelial ovarian cancer platinum resistance recurrence identification using routine clinical data by Li-Rong Yang, Mei Yang, Liu-Lin Chen, Yong-Lin Shen, Yuan He, Zong-Ting Meng, Wan-Qi Wang, Feng Li, Zhi-Jin Liu, Lin-Hui Li, Yu-Feng Wang, Xin-Lei Luo

“…Following this screening process, five machine learning algorithms were employed to develop predictive models based on the selected variables. …”
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Identification and validation of key biomarkers associated with immune and oxidative stress for preeclampsia by WGCNA and machine learning by Tiantian Yu, Tiantian Yu, Tiantian Yu, Guiying Wang, Guiying Wang, Guiying Wang, Xia Xu, Xia Xu, Xia Xu, Jianying Yan, Jianying Yan, Jianying Yan

“…This involved integrating WGCNA, GO and KEGG pathway analyses, constructing PPI networks, applying machine learning algorithms, performing gene GSEA, and conducting immune infiltration analysis to identify the key hub genes related to oxidative stress. …”
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Expression Characteristics and Prognostic Value of KLRG2 in Endometrial Cancer: A Comprehensive Analysis Based on Multi-Omics Data by Xiaoyan Huang, Ailian Li, Dianbo Xu

“…High KLRG2 expression independently predicted worse overall survival (HR = 3.08, 95% CI = 1.92–4.96) and progression-free interval (HR = 1.98, 95% CI = 1.37–2.87). …”
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Combining a Risk Factor Score Designed From Electronic Health Records With a Digital Cytology Image Scoring System to Improve Bladder Cancer Detection: Proof-of-Concept Study by Sandie Cabon, Sarra Brihi, Riadh Fezzani, Morgane Pierre-Jean, Marc Cuggia, Guillaume Bouzillé

“…MethodsThe first step relied on designing a predictive model based on clinical data (ie, risk factors identified in the literature) extracted from the clinical data warehouse of the Rennes Hospital and machine learning algorithms (logistic regression, random forest, and support vector machine). …”
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Mechanisms of drug resistance to neoadjuvant chemotherapy in breast cancer by K. A. Aliev, E. Yu. Zyablitskaya, T. P. Makalish, L. E. Sorokina, E. R. Asanova

“…The presented results can serve as the basis for the creation of diagnostic algorithms that have predictive value regarding the effectiveness of NCT, and also to help identify new targets to justify the use of combined breast cancer treatments in the early stage.…”
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The UK Biobank mental health enhancement 2022: Methods and results. by Katrina A S Davis, Jonathan R I Coleman, Mark Adams, Gerome Breen, Na Cai, Helena L Davies, Kelly Davies, Alexandru Dregan, Thalia C Eley, Elaine Fox, Jo Holliday, Christopher Hübel, Ann John, Aliyah S Kassam, Matthew J Kempton, William Lee, Danyang Li, Jared Maina, Rose McCabe, Andrew M McIntosh, Sian Oram, Marcus Richards, Megan Skelton, Fenella Starkey, Abigail R Ter Kuile, Laura M Thornton, Rujia Wang, Zhaoying Yu, Johan Zvrskovec, Matthew Hotopf

“…It includes established measures, such as the PHQ-9 for current depression and CIDI-SF for lifetime panic, as well as bespoke questions. Algorithms and R code were developed to facilitate analysis.…”
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Deployment of real-time particle detection monitoring system in operating theatres for airborne contamination assessments: a methodological evaluation by Frans Stålfelt, Johan Tenghamn, Henrik Malchau, Karin Svensson Malchau

“…Future research should focus on integrating predictive algorithms and machine-learning to enhance clinical utility and drive improvements in surgical safety. …”
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Digital Self-Management Intervention Paths for Early Breast Cancer Patients: Results of a Pilot Study by Paula Poikonen-Saksela, Evangelos Karademas, Leena Vehmanen, Meri Utriainen, Haridimos Kondylakis, Konstadina Kourou, Georgios C. Manikis, Eleni Kolokotroni, Panagiotis Argyropaidas, Berta Sousa, Ruth Pat Horenczyk, Ketti Mazzocco, Johanna Mattson

“…Based on these answers and predictive algorithms for anxiety and depression, they were guided onto one or several digital intervention paths. …”
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Identification and validation of biomarkers, construction of diagnostic models, and investigation of immunological infiltration characteristics for idiopathic frozen shoulder by Han-tao Jiang, Li-ping Shen, Meng-Qi Pang, Min-jiao Wu, Jiang Li, Wei-jie Gong, Gang Jin, Rang-teng Zhu

“…At the outset, we conducted differential expression analysis, weighted gene co-expression network analysis (WGCNA), and utilized the cytoHubba plugin, complemented by two machine learning algorithms, receiver operating characteristic (ROC) analysis, and expression level evaluation to identify biomarkers for FS. …”
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