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  1. 20481

    Type 1 diabetes prevention clinical trial simulator: Case reports of model‐informed drug development tool by Juan Francisco Morales, Marian Klose, Yannick Hoffert, Jagdeep T. Podichetty, Jackson Burton, Stephan Schmidt, Klaus Romero, Inish O'Doherty, Frank Martin, Martha Campbell‐Thompson, Michael J. Haller, Mark A. Atkinson, Sarah Kim

    Published 2024-08-01
    “…To increase the size of the population pool, we generated virtual populations using multivariate normal distribution and ctree machine learning algorithms. As an output, power was calculated, which summarizes the probability of success, showing a statistically significant difference in the time distribution until the T1D diagnosis between the two arms. …”
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  2. 20482

    Plasma FGF2 and YAP1 as novel biomarkers for MCI in the elderly: analysis via bioinformatics and clinical study by Yejing Zhao, Yejing Zhao, Xiang Wang, Jie Zhang, Yanyan Zhao, Yi Li, Ji Shen, Ying Yuan, Jing Li

    Published 2025-08-01
    “…To address this gap, datasets GSE29378 and GSE12685 were selected to screen differentially expressed genes (DEGs), and hub genes were identified by different algorithms. A total of 350 DEGs were identified in bioinformatics data mining. …”
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  3. 20483

    Dynamic Dwell Time Adjustment in Wire Arc-Directed Energy Deposition: A Thermal Feedback Control Approach by Md Munim Rayhan, Abderrachid Hamrani, Fuad Hasan, Tyler Dolmetsch, Arvind Agarwal, Dwayne McDaniel

    Published 2025-04-01
    “…Future work should focus on integrating multi-axis thermal sensors, extending the framework to multi-material deposition scenarios and implementing machine learning algorithms for predictive thermal modeling.…”
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  4. 20484

    Evaluating Material Parameter Influence on Drapability Using VStitcher by Malin Schiller, Soraya Flohr, Jeanne Marisol Delmas, Anja Krüger, Anne-Marie Miene, Patrizia Zimmermann, Lena Wolf, Miriam Seffers, Michelle-Sophie Ruchay-Drammeh, Ulrike Reinhardt, Lilia Sabantina

    Published 2025-01-01
    “…It is a matter not only of generating photo-realistic images in 3D garment simulations, but also of making reliable predictions about the physical behavior of textile materials in order to achieve realistic outcomes. …”
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  5. 20485

    Machine learning identifies lipid-associated genes and constructs diagnostic and prognostic models for idiopathic pulmonary fibrosis by Xingren Liu, Junmei Song, Shujin Guo, Yi Liao, Jun Zou, Liqing Yang, Caiyu Jiang

    Published 2025-07-01
    “…Genes from this module were used to construct diagnostic and prognostic models, which demonstrated strong predictive performance across multiple validation datasets. …”
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  6. 20486

    The role of LAMA5 in breast cancer progression and its potential in immunotherapy by Xiaoli Zhang, Hongfang Yan, Lihan Bie, Zheng Xu, Xiaoyang Yao, Zhilan Li, Chengshan He, Zhouhong Xiang, Xiudi Jiang

    Published 2025-07-01
    “…Immune infiltration was evaluated using CIBERSORT and ESTIMATE algorithms. Single-cell RNA sequencing and spatial transcriptomics were used to explore the spatial distribution and cellular localization of LAMA5. …”
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  7. 20487

    Preoperative digital 6-minute walk test reveals risk of postoperative pulmonary complications in patients undergoing heart valve surgery: a pilot feasibility study by Lixuan Li, Yuqiang Wang, Zhengbo Zhang, Zeruxin Luo, Wenqing Wang, Jiachen Wang, Xiaoli Liu, Ying Shi, Tian Yuan, Yong Fan, Hong Liang, Yingqiang Guo, Buqing Wang, Jing Wang, Jiaoxue Deng

    Published 2025-07-01
    “…We extracted 94 physiological features across 6MWT phases (baseline, walking, recovery) and clinical variables, developing predictive models using five machine learning algorithms evaluated through rigorous five-fold cross-validation. …”
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    Article
  8. 20488

    Mapping the global risk of chikungunya virus endemicity and autochthonous transmission following importation by Yu-Feng Yang, Yun-Bo Qiu, Qiang Xu, Rui-Cheng Gao, Tian Tang, Yao Tian, Yan-He Wang, Sheng-Hong Lin, Yun-Dong Shi, Long-Tao Chen, Yan Zhang, Jun Ma, Chen-Long Lv, Guo-Lin Wang, Hai-Feng Pan, Wei Liu, Li-Qun Fang

    Published 2025-09-01
    “…Three machine learning algorithms were utilized to analyze the ecological factors associated with CHIKV occurrences in regions characterized by endemic or autochthonous transmission following importation. …”
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  9. 20489

    Applications of molecular dynamics in nanomaterial design and characterization - A review by Md. Aminul Islam, S M Maksudur Rahman, Juhi Jannat Mim, Safiullah Khan, Fardin Khan, Md. Ahadul Islam Patwary, Nayem Hossain

    Published 2025-05-01
    “…In addition, MD is a powerful method for predicting mechanical, thermal, and electronic properties of nanomaterials in different environments. …”
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    Article
  10. 20490

    METTL1-driven nucleotide metabolism reprograms the immune microenvironment in hepatocellular carcinoma: a multi-omics approach for prognostic biomarker discovery by Xie Weng, Yangyue Huang, Zhuoya Fu, Xingli Liu, Fuli Xie, Jiale Wang, Qiaohua Zhu, Dayong Zheng, Dayong Zheng

    Published 2025-04-01
    “…Moreover, the prognostic model integrating METTL1 expression and immune checkpoint profiles shows strong predictive performance across independent cohorts, highlighting its potential clinical utility.ConclusionThis study highlights the innovative role of METTL1-driven nucleotide metabolism reprogramming in reshaping the immune microenvironment of HCC. …”
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  11. 20491

    Experimental validation of cuproptosis-associated molecular signatures and their immunological implications in pulmonary tuberculosis by Xiaofang Liu, Xiaofang Liu, Qianqian Ma, Zhiming Li, Yong Xue, Jie Mi, Yuxi Li, Chunfeng Bai, Donglin Guo, Yinping Liu, Yan Liang, Jianqin Liang, Xueqiong Wu

    Published 2025-07-01
    “…Hub CRGs were screened out via least absolute shrinkage and selection operator (LASSO) regression and random forest (RF) algorithms. Diagnostic models were subsequently constructed and validated. …”
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  12. 20492
  13. 20493

    Development of a robust FT-IR typing system for Salmonella enterica, enhancing performance through hierarchical classification by Diego Fredes-García, Javiera Jiménez-Rodríguez, Alejandro Piña-Iturbe, Pablo Caballero-Díaz, Tamara González-Villarroel, Fernando Dueñas, Aniela Wozniak, Aiko D. Adell, Andrea I. Moreno-Switt, Patricia García

    Published 2025-07-01
    “…The IR Biotyper was used to acquire spectra from these isolates. Machine learning algorithms, including support vector machines, were trained to classify the isolates. …”
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  14. 20494

    Pharmacological potential of 6,11-dihydro[1,2,4]triazolo[4’,3’:1,6]-pyrido[3,4-b]-5-carboxylic acid and its esters by S. O. Fedotov, A. S. Hotsulia

    Published 2025-03-01
    “…The molecular docking method, based on computational algorithms, has been used to predict and study interactions, including the identification of potential binding sites, estimation of energy parameters and spatial configuration of molecules. …”
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  15. 20495

    Molecular subtype of recurrent implantation failure reveals distinct endometrial etiology of female infertility by Jing Yang, Lingtao Yang, Ying Zhou, Fengyang Cao, Hongkun Fang, Huan Ma, Jun Ren, Chunyu Huang, Lianghui Diao, Qiyuan Li, Qionghua Chen

    Published 2025-07-01
    “…A molecular classifier (MetaRIF) was developed using the optimal F-score from 64 combinations of machine learning algorithms. Candidate therapeutic compounds were predicted using the Connectivity Map (CMap) database. …”
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  16. 20496
  17. 20497
  18. 20498
  19. 20499

    The role of artificial intelligence in managing hospitalized patients with mental illness: a scoping review by Md Samiun, Moustaq Karim Khan Rony, Sumaiya Yeasmin, Mia Md Tofayel Gonee Manik, Anupom Debnath, Mustakim Bin Aziz, Afia Fairooz Tasnim, Sadia Islam Nilima

    Published 2025-07-01
    “…Despite these advancements, challenges were noted, such as algorithmic biases due to non-diverse training data, privacy and security risks for sensitive patient information, and clinician resistance stemming from concerns about autonomy and ethical implications of AI-supported clinical decisions. …”
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    Article
  20. 20500

    Towards accurate L4 ocean colour products: Interpolating remote sensing reflectance via DINEOF by Christian Marchese, Simone Colella, Vittorio Ernesto Brando, Maria Laura Zoffoli, Gianluca Volpe

    Published 2024-12-01
    “…Our outcomes show that this “upstream interpolation” method can generate a consistent Rrs dataset, thereby improving the accuracy of L4 Chl predictions when used as input in algorithms for remote Chl estimation. …”
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