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Identification of M2 macrophage-related genes associated with diffuse large B-cell lymphoma via bioinformatics and machine learning approaches
Published 2025-04-01“…Using the Least Absolute Shrinkage and Selection Operator (LASSO), Support Vector Machine Recursive Feature Elimination (SVM-RFE), and Random Forest (RF) algorithms, we screened for seven potential diagnostic biomarkers with strong diagnostic capabilities: SMAD3, IL7R, IL18, FAS, CD5, CCR7, and CSF1R. …”
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1362
Integrating equity, diversity, and inclusion throughout the lifecycle of artificial intelligence for healthcare: a scoping review.
Published 2025-07-01“…Previous research has shown that AI models improve when socio-demographic factors such as gender and race are considered. …”
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1363
Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke
Published 2025-08-01“…Functional enrichment, gene set enrichment analysis (GSEA), and protein–protein interaction (PPI) analyses were performed. Hub genes were screened using LASSO, RandomForest, and SVM-RFE algorithms. …”
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1364
Identification of markers correlating with mitochondrial function in myocardial infarction by bioinformatics.
Published 2024-01-01“…The 10 MI-related hub MitoDEGs were then obtained by eight different algorithms. Immunoassays showed a significant increase in monocyte macrophage and T cell infiltration. …”
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1365
Locating and quantifying CH<sub>4</sub> sources within a wastewater treatment plant based on mobile measurements
Published 2025-04-01“…We utilized a multi-source Gaussian plume model combined with a genetic algorithm inversion framework, designed to locate major sources within the plant and quantify the corresponding <span class="inline-formula">CH<sub>4</sub></span> emission fluxes. …”
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1366
Schizophrenia Detection and Classification: A Systematic Review of the Last Decade
Published 2024-11-01“…Additionally, the analysis underscores common challenges, including dataset limitations, variability in preprocessing approaches, and the need for more interpretable models. Conclusions: This study provides a comprehensive evaluation of AI-based methods in SZ prognosis, emphasizing the strengths and limitations of current approaches. …”
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1367
Health inequities in medical crowdfunding: a systematic review
Published 2025-06-01“…In regions with high medical debt or limited insurance coverage, more crowdfunding campaigns appeared, but with lower overall success. …”
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1368
Computer-assisted analysis of routine EEG to identify hidden biomarkers of epilepsy: A systematic review
Published 2024-12-01“…The computed biomarkers were based on linear (43%), non-linear (27%), connectivity (38%), and convolutional neural networks (10%) models. The risk of bias was high or unclear in all studies, more commonly from spectrum effect and data leakage. …”
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1369
Identification of aging-related biomarkers and immune infiltration analysis in renal stones by integrated bioinformatics analysis
Published 2025-07-01“…Using logistic regression, SVM, and LASSO regression algorithms, a successful early-diagnosis model for RS was developed, yielding 7 key genes: CNR1, KIT, HTR2A, DES, IL33, UCP2, and PPT1. …”
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1370
Identification of potential metabolic biomarkers and immune cell infiltration for metabolic associated steatohepatitis by bioinformatics analysis and machine learning
Published 2025-05-01“…Protein-Protein Interaction (PPI) network and machine learning algorithms, including Least Absolute Shrinkage and Selection Operator (LASSO) regression, Support Vector Machine-Recursive Feature Elimination (SVM-RFE), and Random Forest (RF), were applied to screen for signature MRDEGs. …”
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1371
Shared pathogenic mechanisms linking obesity and idiopathic pulmonary fibrosis revealed by bioinformatics and in vivo validation
Published 2025-07-01“…Functional enrichment (GO/KEGG), protein-protein interaction (PPI) networks, and machine learning algorithms were applied to screen hub genes, validated by ROC curves. …”
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1372
Prediction and validation of anoikis-related genes in neuropathic pain using machine learning.
Published 2025-01-01“…We also used rats to construct an NP model and validated the analyzed hub genes using hematoxylin and eosin (H&E) staining, real-time polymerase chain reaction (PCR), and Western blotting assays.…”
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1373
Prognostic, oncogenic roles, and pharmacogenomic features of AMD1 in hepatocellular carcinoma
Published 2024-12-01“…Univariate Cox regression analysis and Pearson correlation were used to screen for AMD1-related genes (ARGs). Multidimensional bioinformatic algorithms were utilized to establish a risk score model for ARGs. …”
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1374
Identification of glucocorticoid-related genes in systemic lupus erythematosus using bioinformatics analysis and machine learning.
Published 2025-01-01“…Furthermore, we utilized least absolute shrinkage and selection operator (LASSO) regression and Random Forest (RF) algorithms to screen for hub genes. We then validated the expression of these hub genes and constructed nomograms for further validation. …”
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1375
Multi-Omics Identification of <i>Fos</i> as a Central Regulator in Skeletal Muscle Adaptation to Long-Term Aerobic Exercise
Published 2025-05-01“…Key feature genes were screened using Lasso regression, SVM-RFE, and Random Forest machine learning algorithms, validated by RT-qPCR, and refined through PPI network analysis. …”
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1376
DEPDC1B, CDCA2, APOBEC3B, and TYMS are potential hub genes and therapeutic targets for diagnosing dialysis patients with heart failure
Published 2025-01-01“…In addition, we further explored potential mechanism and function of hub genes in HF of patients with MHD through GSEA, immune cell infiltration analysis, drug analysis and establishment of molecular regulatory network.ResultsTotally 23 candidate genes were screened out by overlapping 673 differentially expressed genes (DEGs) and 147 key module genes, of which four hub genes (DEPDC1B, CDCA2, APOBEC3B and TYMS) were obtained by two machine learning algorithms. …”
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1377
Exploration of biomarkers for predicting the prognosis of patients with diffuse large B-cell lymphoma by machine-learning analysis
Published 2025-08-01“…Moreover, four hub genes (CXCL9, CCL18, C1QA and CTSC) were significantly screened from the three datasets using RF algorithms. …”
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1378
Identification of clinical diagnostic and immune cell infiltration characteristics of acute myocardial infarction with machine learning approach
Published 2025-07-01“…Machine learning algorithms (Support Vector Machine (SVM), Random Forest (RF) and Least Absolute Shrinkage and Selection Operator (LASSO)) were applied to identify hub genes. …”
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1379
Leveraging Artificial Intelligence and Data Science for Integration of Social Determinants of Health in Emergency Medicine: Scoping Review
Published 2024-10-01“…With a significant focus on the ED and notable NLP model performance, there is an imperative to standardize SDOH data collection, refine algorithms for diverse patient groups, and champion interdisciplinary synergies. …”
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1380
MSGEGA: Multiscale Gaussian Enhancement and Global-Aware Network for Infrared Small Target Detection
Published 2025-01-01“…Specifically, the proposed method demonstrates significant advantages on the screened dataset, achieving an AUC of 0.992. At a detection rate of 0.871, it maintains a false alarm rate of 0.9<italic>e</italic>-5, outperforming all comparison algorithms. …”
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