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Analysis of immune characteristics and inflammatory mechanisms in COPD patients: a multi-layered study combining bulk and single-cell transcriptome analysis and machine learning
Published 2025-07-01“…Inflammatory-related COPD feature genes were selected using Lasso regression and random forest algorithms, and a COPD risk prediction model was constructed. …”
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662
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663
"Non-destructive and rapid determination of bound styrene content of styrene-butadiene rubber latex using near-infrared spectroscopy"
Published 2024-12-01“…A non-destructive and rapid determination of bound styrene content in styrene-butadiene rubber latex was studied using near-infrared spectroscopy diffuse transmission method combined with chemometrics, bound styrene content in styrene-butadiene rubber latex was determined by refractive index method, near-infrared spectral data of styrene-butadiene rubber latex were collected using Fourier transform near-infrared spectrometer, Kennard-Stone algorithm was used to divide the calibration set and validation set, partial least squares regression quantitative analysis model was established by combining the spectral preprocessing methods, such as multiple scattering correction method, second-order derivatives and Norris smoothing, etc, and the influence of screening spectral feature variables by interval partial least squares algorithm on the quantitative ana-lysis model was finally investigated. …”
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664
Characterization of lactylation modification subtypes and the promoting role of CCL20 in hepatocellular carcinoma progression
Published 2025-07-01“…The CIBERSORT algorithm was utilized to analyze immune cell infiltration. …”
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665
Machine learning prediction model with shap interpretation for chronic bronchitis risk assessment based on heavy metal exposure: a nationally representative study
Published 2025-05-01“…Methods Weighted logistic regression was used to assess the association of 14 blood and urine heavy metals with CB based on nationally representative samples from the 2005–2015 National Health and Nutrition Examination Survey (NHANES). The Boruta algorithm was further applied to screen the characteristic variables and construct 10 ML models. …”
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666
Glypican-3 regulated epithelial mesenchymal transformation-related genes in osteosarcoma: based on comprehensive tumor microenvironment profiling
Published 2025-05-01“…The least absolute shrinkage and selection operator (LASSO) algorithm was applied to screen candidate genes for developing a prognostic model. …”
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667
Identification of potential pathogenic genes associated with the comorbidity of rheumatoid arthritis and renal fibrosis using bioinformatics and machine learning
Published 2025-07-01“…Subsequently, functional enrichment analysis was performed to clarify the biological functions of these genes. Machine learning algorithms were used to screen for the hub RA-RF differential expression genes, and then a Logistic Regression (LR) model was constructed. …”
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668
Development of a machine learning prognostic model for early prediction of scrub typhus progression at hospital admission based on clinical and laboratory features
Published 2025-12-01“…Eighteen objective clinical and laboratory features collected at admission were screened using various feature selection algorithms, and used to construct models based on six machine learning algorithms.Results The model based on Gradient Boosting Decision Tree using 14 features screened by Recursive Feature Elimination was evaluated as the optimal one. …”
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669
Genome-wide expression in human whole blood for diagnosis of latent tuberculosis infection: a multicohort research
Published 2025-05-01“…A Naive Bayes (NB) model incorporating these two markers demonstrated robust diagnostic performance: training set AUC: median = 0.8572 (inter-quartile range 0.8002, 0.8708), validation AUC = 0.5719 (0.51645, 0.7078), and subgroup AUC = 0.8635 (0.8212, 0.8946).ConclusionOur multicohort analysis established an NB-based diagnostic model utilizing S100A12/S100A8, which maintains diagnostic accuracy across diverse geographic, ethnic, and clinical variables (including HIV co-infection), highlighting its potential for clinical translation in LTBI/ATB differentiation.…”
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670
Identification and Validation of Circadian Rhythm‐Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning
Published 2025-06-01“…Results Six hub genes related to CRs (CCND1, FOXO1, FRMD8, NTRK2, PRRT1, and TFPI) were screened out. Immune infiltration analysis revealed that the IVDD group had significantly more M0 macrophages and significantly fewer follicular helper T cells than those of the control group. …”
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671
AI-based Assessment of Risk Factors for Coronary Heart Disease in Patients With Diabetes Mellitus and Construction of a Prediction Model for a Treatment Regimen
Published 2025-06-01“…Conclusions: Using machine-learning algorithms, we built a prediction model of a treatment plan for patients with concomitant DM and CHD by integrating patients' information and screened the best feature set containing 15 features, which provides help and strategies to develop the best treatment plan for patients with concomitant DM and CHD.…”
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672
Low-cost and scalable machine learning model for identifying children and adolescents with poor oral health using survey data: An empirical study in Portugal.
Published 2025-01-01“…Such a model could enable scalable and cost-effective screening and targeted interventions, optimizing limited resources to improve oral health outcomes. …”
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673
A novel prediction model for the prognosis of non-small cell lung cancer with clinical routine laboratory indicators: a machine learning approach
Published 2024-11-01“…Finally, critical variables in the optimal model were screened based on the interpretable algorithms to build a decision tree to facilitate clinical application. …”
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674
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An efficient hybrid Hopfield convolutional neural network for detecting spam bots in Twitter platform
Published 2025-12-01“…The extracted features are then subjected to feature selection, where a meta-heuristic-based optimization algorithm called the Binary Golden Search Optimization algorithm (BGSO) is used. …”
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676
A Dual-Variable Selection Framework for Enhancing Forest Aboveground Biomass Estimation via Multi-Source Remote Sensing
Published 2025-07-01“…The dual-variable selection strategy integrates SHAP with the Pearson correlation coefficient (PC), RF, EN, and Lasso to enhance feature screening robustness and interpretability. The results of the study showed that Lasso-SHAP dual-variate screening was more stable than SHAP univariate screening. …”
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677
Mitochondrial autophagy-related gene signatures associated with myasthenia gravis diagnosis and immunity
Published 2025-12-01“…Multiple machine learning algorithms were applied to screen and verify the diagnostic genes of intersection genes. …”
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678
Development and validation of an early predictive model for hemiplegic shoulder pain: a comparative study of logistic regression, support vector machine, and random forest
Published 2025-06-01“…ObjectiveIn this study, we aim to identify the predictive variables for hemiplegic shoulder pain (HSP) through machine learning algorithms, select the optimal model and predict the occurrence of HSP.MethodsData of 332 stroke patients admitted to a tertiary hospital in Zhejiang Province from January 2022 to January 2023 were collected. …”
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679
Machine Learning-Assisted NIR Spectroscopy for Dynamic Monitoring of Leaf Potassium in Korla Fragrant Pear
Published 2025-07-01“…By measuring leaf potassium content at the fruit setting, expansion, and maturity stages (decreasing from 1.60% at fruit setting to 1.14% at maturity), this study reveals its dynamic change pattern and establishes a high-precision prediction model by combining near-infrared spectroscopy (NIRS) with machine learning algorithms. …”
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680
Exploring patterns in pediatric type 1 diabetes care and the impact of socioeconomic status
Published 2025-04-01“…Higher socioeconomic status is associated with care that more closely adheres to clinical guidelines.…”
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